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The map label for this gene is glpD [H]

Identifier: 134301341

GI number: 134301341

Start: 229118

End: 230650

Strand: Direct

Name: glpD [H]

Synonym: FTW_0222

Alternate gene names: 134301341

Gene position: 229118-230650 (Clockwise)

Preceding gene: 134301340

Following gene: 134301342

Centisome position: 12.07

GC content: 33.92

Gene sequence:

>1533_bases
ATGAAAAAAGAATACGATATAATAATAATTGGTGGTGGCGCAACTGGCTTTGGTTGTGCTATTGAAGCAGTTTCTCGAGG
TTACAAAACTCTACTTCTAGAAGCGAGTGATTTTGGTAAAGGAACCTCTTCGAAGTCAACAAAATTGATTCATGGTGGTT
TAAGGTATCTAGAGAACTTTGACTTTGCTTTAGTTAAGGAAGGCTTAGAAGAGAGATTCTCTTTTTTACATAATGCGCCA
CATTTGACACATAAACAATCTTATCTTATTCCAACGCGTAGCTATTTTGAAACTATTAAATATACTATTGGTGTTAAGCT
TTATGAGTTTTTATCAGGTAAGTATAAAATTGGTAAAAGTTATAATCTAAACAAACATCAAACATTAGCAGAGTTACCAA
ATATAGAAGCATCAAAGCTTAAAAAAAGCCTTGTGTATTATGATGGTCAATTTGATGATACTAGGTTGCTTATTTCTTTG
ATGAAAACTTTTGAAGCAAAAGGCGGTGTTGCTCTTAATTATCATAAAGTAGAAAAGATATTTAGTTCAACAGATTCAAA
ATTAGATACTGTAAAAGTTGTAGATACTTTATCGGGTGAACAAAAAGAATTTACAGCTAAACATATAATCAATGCTACAG
GTACATTTAGCGATAAAACTATAAGCTTAGCAAATCAGCAAGATGCGCATAAGTATGTCTCTGTTGCACAGGGAACGCAT
ATTGTTTTTGATAGAGAGAAGTTTCCAACAGAGCACGCAATCTTAATCCCAGAAACAGAAGATGGCAGGGTATTATTTAT
TTTGCCTTGGCACGATCATCTAATAGTTGGTACTACTGATATCAAAAAAGAAGTACCAAGTCTTGAGCCGAGAGCTGATA
AATCTGAGATTGATTTTATCTTAAAGACTTTTAATCAATATGCAAAAGACAAGGCAACTATCGTAGATATTAAGTCAGTT
TACTGTGGTCAGCGTCCTTTGGTAACTCCAAAAAAAGCTAAAAATTCCGCAAAAATATCGCGCAAGCATGAAATTGTAGA
GTCAAAAGATGGCTTAATAACAGTTGTTGGAGGTAAGTGGACTATTTTTAGAAGAATGGGGCAAGATACTCTAGATTATA
TAGAAACTAAAAAAATAGCACAGAAAATATCTAAAACATCGGATCAGTTACTTATAGATGCTATTGAGCCAAAAGATACG
TATCCTCTAAAAGTTTATGGTAAAAATGCTGAAGATATCAAAACTATTCAAAATGAGCTTGATAATTTTGAGCTTTTGGC
GAGAGGTCTACCATACTATCAGGCAGAGGTTGTATATCATGTACGACATGAAAAAGCCAAAACTATAGAGGATGTTCTTG
CGCGTCGAACTAGAGCAGCATTTTTGGATATCAAAGCAAGTATTGATGCTGCACCAAAGGTAGCTGAGCTTATGGCAAAG
GAGCTTGGTAAAGATGAGGTTTGGCAAAACCAGCAAATTGATAGTTTCATAGAATTTTCTAAAAACTTTAATGTTGAAGA
GCTGTATAAGTAG

Upstream 100 bases:

>100_bases
AAATAAAATCAACTCCTTTCAAGATTATTAAAATGAGTTGACGATACAAGAACAGTGGTGATAAGCCTAGATTAAATTTT
TAATAAAAGACTATAAACAA

Downstream 100 bases:

>100_bases
AGGAAGTTTATGTTAACAGCATGTATAGCAGAATTAATAGGCACAATGCTACTTATCTTATTGGGTAATGGTGTTGTTGC
TGGAGTAGTTTTAAATAAGA

Product: FAD -dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKKEYDIIIIGGGATGFGCAIEAVSRGYKTLLLEASDFGKGTSSKSTKLIHGGLRYLENFDFALVKEGLEERFSFLHNAP
HLTHKQSYLIPTRSYFETIKYTIGVKLYEFLSGKYKIGKSYNLNKHQTLAELPNIEASKLKKSLVYYDGQFDDTRLLISL
MKTFEAKGGVALNYHKVEKIFSSTDSKLDTVKVVDTLSGEQKEFTAKHIINATGTFSDKTISLANQQDAHKYVSVAQGTH
IVFDREKFPTEHAILIPETEDGRVLFILPWHDHLIVGTTDIKKEVPSLEPRADKSEIDFILKTFNQYAKDKATIVDIKSV
YCGQRPLVTPKKAKNSAKISRKHEIVESKDGLITVVGGKWTIFRRMGQDTLDYIETKKIAQKISKTSDQLLIDAIEPKDT
YPLKVYGKNAEDIKTIQNELDNFELLARGLPYYQAEVVYHVRHEKAKTIEDVLARRTRAAFLDIKASIDAAPKVAELMAK
ELGKDEVWQNQQIDSFIEFSKNFNVEELYK

Sequences:

>Translated_510_residues
MKKEYDIIIIGGGATGFGCAIEAVSRGYKTLLLEASDFGKGTSSKSTKLIHGGLRYLENFDFALVKEGLEERFSFLHNAP
HLTHKQSYLIPTRSYFETIKYTIGVKLYEFLSGKYKIGKSYNLNKHQTLAELPNIEASKLKKSLVYYDGQFDDTRLLISL
MKTFEAKGGVALNYHKVEKIFSSTDSKLDTVKVVDTLSGEQKEFTAKHIINATGTFSDKTISLANQQDAHKYVSVAQGTH
IVFDREKFPTEHAILIPETEDGRVLFILPWHDHLIVGTTDIKKEVPSLEPRADKSEIDFILKTFNQYAKDKATIVDIKSV
YCGQRPLVTPKKAKNSAKISRKHEIVESKDGLITVVGGKWTIFRRMGQDTLDYIETKKIAQKISKTSDQLLIDAIEPKDT
YPLKVYGKNAEDIKTIQNELDNFELLARGLPYYQAEVVYHVRHEKAKTIEDVLARRTRAAFLDIKASIDAAPKVAELMAK
ELGKDEVWQNQQIDSFIEFSKNFNVEELYK
>Mature_510_residues
MKKEYDIIIIGGGATGFGCAIEAVSRGYKTLLLEASDFGKGTSSKSTKLIHGGLRYLENFDFALVKEGLEERFSFLHNAP
HLTHKQSYLIPTRSYFETIKYTIGVKLYEFLSGKYKIGKSYNLNKHQTLAELPNIEASKLKKSLVYYDGQFDDTRLLISL
MKTFEAKGGVALNYHKVEKIFSSTDSKLDTVKVVDTLSGEQKEFTAKHIINATGTFSDKTISLANQQDAHKYVSVAQGTH
IVFDREKFPTEHAILIPETEDGRVLFILPWHDHLIVGTTDIKKEVPSLEPRADKSEIDFILKTFNQYAKDKATIVDIKSV
YCGQRPLVTPKKAKNSAKISRKHEIVESKDGLITVVGGKWTIFRRMGQDTLDYIETKKIAQKISKTSDQLLIDAIEPKDT
YPLKVYGKNAEDIKTIQNELDNFELLARGLPYYQAEVVYHVRHEKAKTIEDVLARRTRAAFLDIKASIDAAPKVAELMAK
ELGKDEVWQNQQIDSFIEFSKNFNVEELYK

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=533, Percent_Identity=35.2720450281426, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI285002231, Length=533, Percent_Identity=35.2720450281426, Blast_Score=322, Evalue=6e-88,
Organism=Escherichia coli, GI2367226, Length=462, Percent_Identity=28.1385281385281, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788574, Length=403, Percent_Identity=23.8213399503722, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17509253, Length=541, Percent_Identity=34.3807763401109, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI115534726, Length=540, Percent_Identity=33.3333333333333, Blast_Score=266, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6322036, Length=588, Percent_Identity=32.8231292517007, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI161077125, Length=543, Percent_Identity=33.7016574585635, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24653942, Length=543, Percent_Identity=33.7016574585635, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24653944, Length=543, Percent_Identity=33.7016574585635, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI20130025, Length=543, Percent_Identity=33.7016574585635, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24586295, Length=540, Percent_Identity=30.7407407407407, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI19921278, Length=535, Percent_Identity=29.3457943925234, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI45550977, Length=400, Percent_Identity=26.75, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57800; Mature: 57800

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEYDIIIIGGGATGFGCAIEAVSRGYKTLLLEASDFGKGTSSKSTKLIHGGLRYLENF
CCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCC
DFALVKEGLEERFSFLHNAPHLTHKQSYLIPTRSYFETIKYTIGVKLYEFLSGKYKIGKS
CHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCC
YNLNKHQTLAELPNIEASKLKKSLVYYDGQFDDTRLLISLMKTFEAKGGVALNYHKVEKI
CCCCHHHHHHHCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHH
FSSTDSKLDTVKVVDTLSGEQKEFTAKHIINATGTFSDKTISLANQQDAHKYVSVAQGTH
HHCCCCCCCEEEEHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCE
IVFDREKFPTEHAILIPETEDGRVLFILPWHDHLIVGTTDIKKEVPSLEPRADKSEIDFI
EEEECCCCCCCCEEEEECCCCCEEEEEEECCCEEEEECHHHHHHCCCCCCCCCHHHHHHH
LKTFNQYAKDKATIVDIKSVYCGQRPLVTPKKAKNSAKISRKHEIVESKDGLITVVGGKW
HHHHHHHHCCCCEEEEEHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCEEEEECCCE
TIFRRMGQDTLDYIETKKIAQKISKTSDQLLIDAIEPKDTYPLKVYGKNAEDIKTIQNEL
EEHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHH
DNFELLARGLPYYQAEVVYHVRHEKAKTIEDVLARRTRAAFLDIKASIDAAPKVAELMAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
ELGKDEVWQNQQIDSFIEFSKNFNVEELYK
HCCHHHHCCCCCHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MKKEYDIIIIGGGATGFGCAIEAVSRGYKTLLLEASDFGKGTSSKSTKLIHGGLRYLENF
CCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCC
DFALVKEGLEERFSFLHNAPHLTHKQSYLIPTRSYFETIKYTIGVKLYEFLSGKYKIGKS
CHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCC
YNLNKHQTLAELPNIEASKLKKSLVYYDGQFDDTRLLISLMKTFEAKGGVALNYHKVEKI
CCCCHHHHHHHCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHH
FSSTDSKLDTVKVVDTLSGEQKEFTAKHIINATGTFSDKTISLANQQDAHKYVSVAQGTH
HHCCCCCCCEEEEHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCE
IVFDREKFPTEHAILIPETEDGRVLFILPWHDHLIVGTTDIKKEVPSLEPRADKSEIDFI
EEEECCCCCCCCEEEEECCCCCEEEEEEECCCEEEEECHHHHHHCCCCCCCCCHHHHHHH
LKTFNQYAKDKATIVDIKSVYCGQRPLVTPKKAKNSAKISRKHEIVESKDGLITVVGGKW
HHHHHHHHCCCCEEEEEHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCEEEEECCCE
TIFRRMGQDTLDYIETKKIAQKISKTSDQLLIDAIEPKDTYPLKVYGKNAEDIKTIQNEL
EEHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHH
DNFELLARGLPYYQAEVVYHVRHEKAKTIEDVLARRTRAAFLDIKASIDAAPKVAELMAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
ELGKDEVWQNQQIDSFIEFSKNFNVEELYK
HCCHHHHCCCCCHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA