Click here to switch to the map view.

The map label for this gene is dnaA [H]

Identifier: 134301170

GI number: 134301170

Start: 46

End: 1521

Strand: Direct

Name: dnaA [H]

Synonym: FTW_0001

Alternate gene names: 134301170

Gene position: 46-1521 (Clockwise)

Preceding gene: NA

Following gene: 134301171

Centisome position: 0.0

GC content: 31.17

Gene sequence:

>1476_bases
ATGACTACATGGGATAAATGTTTAAAAAAAATAAAAAAAAACCTTTCTACGTTTGAGTATAAGACGTGGATAAAGCCTAT
CCATGTGGAGCAAAATAGTAACTTATTCACAGTTTACTGTAACAATGAATATTTCAAAAAACATATAAAATCTAAGTATG
GAAATCTTATTTTATCAACAATCCAAGAGTGTCATGGTAATGATTTAATTATTGAATATTCTAATAAAAAATTCTCTGGC
GAAAAAATTACTGAGGTTATCACAGCTGGACCACAAGCTAATTTTTTTAGCACAACAAGTGTTGAGATAAAAGATGAATC
AGAAGATACAAAAGTAGTACAAGAACCTAAAATATCAAAGAAGTCTAATAGTAAAGACTTTTCTTCATCACAAGAGTTAT
TCGGTTTTGACGAAGCTATGCTAATTACAGCAAAAGAAGATGAGGAATACTCTTTTGGTTTACCGTTAAAAGAAAAATAT
GTTTTTGATAGTTTTGTTGTTGGAGATGCTAACAAAATTGCTAGAGCAGCGGCTATGCAGGTATCGATAAATCCAGGTAA
ATTACATAACCCTTTATTCATTTATGGTGGTAGTGGTTTAGGTAAAACTCACTTAATGCAAGCAATAGGTAATCATGCAA
GAGAAGTTAATCCTAATGCCAAAATTATTTATACAAATTCAGAACAATTTATTAAAGATTATGTAAATTCTATTCGTTTA
CAAGATCAAGATGAGTTTCAAAGAGTTTATAGATCTGCGGATATACTTTTGATTGATGATATTCAATTTATCGCTGGTAA
AGAGGGTACTGCTCAGGAGTTTTTCCATACTTTTAATGCATTGTATGAAAATGGTAAACAGATAATTCTAACTAGTGATA
AGTATCCAAATGAAATAGAAGGGCTTGAAGAAAGACTAGTTTCGCGTTTTGGTTATGGTTTAACAGTTTCTGTTGATATG
CCAGATTTAGAAACCAGAATTGCTATCTTGCTCAAAAAAGCTCATGATTTAGGTCAGAAATTACCTAACGAAACAGCAGC
TTTTATTGCTGAGAATGTACGTACTAATGTCAGAGAACTAGAAGGTGCTCTAAATAGGGTTCTTACTACCTCTAAATTTA
ATCATAAAGATCCTACTATCGAAGTAGCACAAGCTTGCTTAAGAGATGTTATAAAAATACAAGAAAAGAAAGTAAAAATA
GATAATATCCAAAAGGTTGTTGCTGATTTTTATAGAATCAGGGTAAAAGATTTAACTTCTAATCAAAGAAGTAGAAATAT
AGCTAGACCAAGACAGATAGCAATGAGTTTAGCACGTGAACTAACATCACATAGTTTGCCAGAAATAGGCAATGCTTTTG
GTGGTAGAGACCATACGACAGTTATGCATGCTGTCAAAGCTATAACTAAATTAAGACAAAGCAATACTTCAATATCGGAT
GATTATGAGTTGCTTTTAAATAAAATTTCTCGTTAA

Upstream 100 bases:

>100_bases
ATTTATTTTTATTGCAATAAAATCTTATCCATTCAATTGATAGTTTTGCCTACATTTGGCTATCCTTTATATTTTAAGGG
TTATTAGGATATTTTTTATT

Downstream 100 bases:

>100_bases
ATAAAATTAGTAACTTTATCAAAGGGGTTTTAAAAAATGAATTTTGTACTAAATAGAGATGACTTACTAAAGCCTTTGCA
ATCTATGCTCTCAGTTGCAA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILSTIQECHGNDLIIEYSNKKFSG
EKITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISKKSNSKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKY
VFDSFVVGDANKIARAAAMQVSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRL
QDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIEGLEERLVSRFGYGLTVSVDM
PDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVRELEGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKI
DNIQKVVADFYRIRVKDLTSNQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISD
DYELLLNKISR

Sequences:

>Translated_491_residues
MTTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILSTIQECHGNDLIIEYSNKKFSG
EKITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISKKSNSKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKY
VFDSFVVGDANKIARAAAMQVSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRL
QDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIEGLEERLVSRFGYGLTVSVDM
PDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVRELEGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKI
DNIQKVVADFYRIRVKDLTSNQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISD
DYELLLNKISR
>Mature_490_residues
TTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILSTIQECHGNDLIIEYSNKKFSGE
KITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISKKSNSKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKYV
FDSFVVGDANKIARAAAMQVSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRLQ
DQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIEGLEERLVSRFGYGLTVSVDMP
DLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVRELEGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKID
NIQKVVADFYRIRVKDLTSNQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISDD
YELLLNKISR

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=491, Percent_Identity=45.6211812627291, Blast_Score=443, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 55813; Mature: 55682

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILST
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHH
IQECHGNDLIIEYSNKKFSGEKITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISK
HHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCEECEEEEEECCCCCHHHHCCCCCCC
KSNSKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKYVFDSFVVGDANKIARAAAMQ
CCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHEEECCHHHHHHHHHEE
VSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRL
EECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCC
QDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIE
CCHHHHHHHHHCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
GLEERLVSRFGYGLTVSVDMPDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVREL
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKIDNIQKVVADFYRIRVKDLTS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
NQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISD
CHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCH
DYELLLNKISR
HHHHHHHHHCC
>Mature Secondary Structure 
TTWDKCLKKIKKNLSTFEYKTWIKPIHVEQNSNLFTVYCNNEYFKKHIKSKYGNLILST
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHH
IQECHGNDLIIEYSNKKFSGEKITEVITAGPQANFFSTTSVEIKDESEDTKVVQEPKISK
HHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCEECEEEEEECCCCCHHHHCCCCCCC
KSNSKDFSSSQELFGFDEAMLITAKEDEEYSFGLPLKEKYVFDSFVVGDANKIARAAAMQ
CCCCCCCCCCHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHEEECCHHHHHHHHHEE
VSINPGKLHNPLFIYGGSGLGKTHLMQAIGNHAREVNPNAKIIYTNSEQFIKDYVNSIRL
EECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCC
QDQDEFQRVYRSADILLIDDIQFIAGKEGTAQEFFHTFNALYENGKQIILTSDKYPNEIE
CCHHHHHHHHHCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
GLEERLVSRFGYGLTVSVDMPDLETRIAILLKKAHDLGQKLPNETAAFIAENVRTNVREL
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EGALNRVLTTSKFNHKDPTIEVAQACLRDVIKIQEKKVKIDNIQKVVADFYRIRVKDLTS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
NQRSRNIARPRQIAMSLARELTSHSLPEIGNAFGGRDHTTVMHAVKAITKLRQSNTSISD
CHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCH
DYELLLNKISR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA