LOCUS       NC_014749              58717 bp    DNA     circular BCT 05-JUL-2011
DEFINITION  Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete
            sequence.
ACCESSION   NC_014749
VERSION     NC_014749.1  GI:313652020
DBLINK      Project: 60821
KEYWORDS    .
SOURCE      Calditerrivibrio nitroreducens DSM 19672
  ORGANISM  Calditerrivibrio nitroreducens DSM 19672
            Bacteria; Deferribacteres; Deferribacterales; Deferribacteraceae.
REFERENCE   1  (bases 1 to 58717)
  AUTHORS   Pitluck,S., Sikorski,J., Zeytun,A., Lapidus,A., Nolan,M., Lucas,S.,
            Hammon,N., Deshpande,S., Cheng,J.F., Tapia,R., Han,C., Goodwin,L.,
            Liolios,K., Pagani,I., Ivanova,N., Mavromatis,K., Pati,A., Chen,A.,
            Palaniappan,K., Hauser,L., Chang,Y.J., Jeffries,C.D., Detter,J.C.,
            Brambilla,E., Djao,O.D., Rohde,M., Spring,S., Goker,M., Woyke,T.,
            Bristow,J., Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C.,
            Klenk,H.P. and Land,M.
  TITLE     Complete genome sequence of Calditerrivibrio nitroreducens type
            strain (Yu37-1)
  JOURNAL   Stand Genomic Sci 4 (1), 54-62 (2011)
   PUBMED   21475587
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58717)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-DEC-2010) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 58717)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Bruce,D., Goodwin,L.,
            Pitluck,S., Kyrpides,N., Mavromatis,K., Ivanova,N., Mikhailova,N.,
            Zeytun,A., Brettin,T., Detter,J.C., Tapia,R., Han,C., Land,M.,
            Hauser,L., Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T.,
            Wu,D., Spring,S., Schroeder,M., Brambilla,E., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (18-NOV-2010) US DOE Joint Genome Institute, 2800
            Mitchell Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CP002348.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4087656
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
                      David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            
            ##MIGS-Data-START##
            investigation_type  :: bacteria_archaea
            project_name        :: Calditerrivibrio nitroreducens Yu37-1, DSM
                                   19672
            collection_date     :: Missing
            lat_lon             :: 36.829513 138.217163
            depth               :: Missing
            alt_elev            :: Missing
            country             :: Japan
            environment         :: Host
            num_replicons       :: 2
            ref_biomaterial     :: DSM 19672, NBRC 101217
            biotic_relationship :: Free living
            trophic_level       :: Missing
            rel_to_oxygen       :: Anaerobe
            isol_growth_condt   :: 18599715
            sequencing_meth     :: WGS
            assembly            :: Newbler v. 2.3 (pre-release)
            finishing_strategy  :: Finished
            GOLD Stamp ID       :: Gi04007
            Type Strain         :: Yes
            Funding Program     :: DOE-GEBA 2009
            Gene Calling Method :: Prodigal 1.4, GenePRIMP
            Isolation Site      :: Terrestrial hot spring; Japan, Nagano,
                                   Yumata
            Cell Shape          :: Vibrio-shaped
            Motility            :: Motile
            Sporulation         :: Nonsporulating
            Temperature Range   :: Thermophile
            Temperature Optimum :: 55C
            pH                  :: 7.0 - 7.5
            Gram Staining       :: Gram-
            Diseases            :: None
            ##MIGS-Data-END##
            
            ##Genome-Assembly-Data-START##
            Finishing Goal           :: Finished
            Current Finishing Status :: Finished
            Assembly Method          :: Newbler v. 2.3
            Genome Coverage          :: 30x
            Sequencing Technology    :: Illumina, 454
            ##Genome-Assembly-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..58717
                     /organism="Calditerrivibrio nitroreducens DSM 19672"
                     /mol_type="genomic DNA"
                     /strain="DSM 19672"
                     /isolation_source="terrestrial hot spring"
                     /db_xref="taxon:768670"
                     /plasmid="pCALNI01"
                     /country="Japan: Nagano, Yumata"
                     /lat_lon="36.829514 N 138.217163 E"
     gene            273..617
                     /locus_tag="Calni_2069"
                     /pseudo
                     /db_xref="GeneID:10004330"
     gene            complement(679..906)
                     /locus_tag="Calni_2070"
                     /db_xref="GeneID:10004271"
     CDS             complement(679..906)
                     /locus_tag="Calni_2070"
                     /note="KEGG: act:ACLA_065780 sugar transporter, putative;
                     SPTR: Sugar transporter, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter, putative"
                     /protein_id="YP_004046699.1"
                     /db_xref="GI:313652021"
                     /db_xref="GeneID:10004271"
                     /translation="MQSANEGLGKKVTKYAGWGITLVATIYTITGYIDIASDASTRAY
                     APLIFIEGGFFIAIGLVVLWLGYRNTNKPKD"
     gene            complement(1147..1653)
                     /locus_tag="Calni_2071"
                     /pseudo
                     /db_xref="GeneID:10004272"
     gene            complement(1818..3566)
                     /locus_tag="Calni_2072"
                     /db_xref="GeneID:10004273"
     CDS             complement(1818..3566)
                     /locus_tag="Calni_2072"
                     /note="InterPro IPR002917;
                     KEGG: dap:Dacet_0622 GTP-binding protein HSR1-related
                     protein;
                     PFAM: GTP-binding protein HSR1-related;
                     SPTR: GTP-binding protein HSR1-related protein;
                     PFAM: Dynamin family"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein HSR1-related protein"
                     /protein_id="YP_004046700.1"
                     /db_xref="GI:313652022"
                     /db_xref="GeneID:10004273"
                     /translation="MSFSTILNFLYRVFFGKNFKRMYEEISVEYDKLRKKYSNLISEN
                     KKLEDEYKNLNIKLIELQLKYSNLLTDYEEIGNLNKKLNDTIEILGKEKETYKIELED
                     LKKIHDNQTLVLKNLHSKYNEIEEERDTFMNKCADLADKIQTLEEEKEKLDEENQKKE
                     REIKILTNERNDLGKKLQAISLILSKEEKQDNSPEKLINLLEKDFVELINKIPYKEEA
                     KTIIKLKSIIERIEFVLSFKDKFSKNIVAICGGFSTGKSSFINSVFFSNDNSNFQLST
                     NITPTTAIPTYVVHGDSLNIKAASINNTLKEIKPEYTSMFDHYNIKDFGFHMRTLVQF
                     LIVSNPFKDYKNICFIDTPGYNPGGSISVEDHEITLKYIDEANVILWLIGIDVNGTIP
                     KSDIDFLRGINSSNKKIYIALNKADTRSLPDIEKIGEAVKNELEKNGIKVEGISAFSS
                     INNQELWYHGKSLFQFLKEEDRPSDLKDSLREELKSIFRDYETFLKSDIKEAESFLSS
                     FKSMELDIFQVGKDEKLAKSTSFYDRLDSLKTKFQSKIAENKKNLADLKNLEEIVLKE
                     FDNLFFKEKRLSLKKI"
     misc_feature    complement(<2832..>3497)
                     /locus_tag="Calni_2072"
                     /note="Chromosome segregation ATPases [Cell division and
                     chromosome partitioning]; Region: Smc; COG1196"
                     /db_xref="CDD:31389"
     misc_feature    complement(2199..>2522)
                     /locus_tag="Calni_2072"
                     /note="Era (E. coli Ras-like protein)-like.  This family
                     includes several distinct subfamilies (TrmE/ThdF, FeoB,
                     YihA (EngG), Era, and EngA/YfgK) that generally show
                     sequence conservation in the region between the Walker A
                     and B motifs (G1 and G3 box motifs)...; Region: Era_like;
                     cd00880"
                     /db_xref="CDD:133256"
     misc_feature    complement(order(2442..2444,2502..2519))
                     /locus_tag="Calni_2072"
                     /note="Switch II region; other site"
                     /db_xref="CDD:133256"
     misc_feature    complement(2505..2516)
                     /locus_tag="Calni_2072"
                     /note="G3 box; other site"
                     /db_xref="CDD:133256"
     misc_feature    complement(2316..2327)
                     /locus_tag="Calni_2072"
                     /note="G4 box; other site"
                     /db_xref="CDD:133256"
     misc_feature    complement(2223..2231)
                     /locus_tag="Calni_2072"
                     /note="G5 box; other site"
                     /db_xref="CDD:133256"
     gene            complement(3689..5941)
                     /locus_tag="Calni_2073"
                     /db_xref="GeneID:10004274"
     CDS             complement(3689..5941)
                     /locus_tag="Calni_2073"
                     /note="KEGG: dap:Dacet_0621 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Dynamin family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046701.1"
                     /db_xref="GI:313652023"
                     /db_xref="GeneID:10004274"
                     /translation="MELLKLFREVEAVVDKNYTILKDDAENLKEDLALEKLEDLEKQL
                     ADLDRDSKTLTIGIVGRVKAGKSSLLNALLFEGESILPKAATPMTASLTLLSYDDKIS
                     AEVEFYTQKDVKEIKKKHDEYLTKLNDLKEKYIEQFKNDEKELQSGNIEKKAEDMAKK
                     ELFEKYIHLQAAYEHYNDMENKGLNQNFSNNEVISADSLEELSKKLLDYVGSQGKYTP
                     YTKSVRIKAPLESLKGVEIVDTPGINDPVVSREARTRELLKNADVVFILSNAGQFLSE
                     EDLDLMDRITMKEGIRELFLVGSQVDLQLHGDEKIKSRGNLFTALENIKKNLADYTRR
                     TIKDLKRNSPEIGDTYNQLIEESKERMFLSSGACYSLYKLFDNKQLWDDNMKIVWKNL
                     TNNYPDFFSEDNKDIALENLKLLSGIVEIVEALEKVKERKQEILKKRSEEIMKAKSQS
                     LRKYIDGLIKAVEERLTKIQSTEIKDLEKNIQELQKKTSNSGVVEHKYDELVEELIDD
                     IKKISRKITMDISKSIYDLQNVGEGYKTEPKNEGRGGLLGFLADFLFGEKKVEENVRI
                     LKTGYVEAELVKSVNNQKISTEEKLEEAIKQWKVKLRRELTSTIREVVGDEFIDKDIM
                     IKSITSIEKSEIDFPSLDDITIPSSLRRRGILKNEDEIEDYRSKLTDFLDDLESEFKD
                     NLNEFSKTIKKNLGEKGSKVIKSIFDKYRIEIENLRKDIESKQFMIDKLNNTSKELKN
                     LKKKVLLQEV"
     misc_feature    complement(5051..5776)
                     /locus_tag="Calni_2073"
                     /note="Ras-like GTPase superfamily. The Ras-like
                     superfamily of small GTPases consists of several families
                     with an extremely high degree of structural and functional
                     similarity. The Ras superfamily is divided into at least
                     four families in eukaryotes: the Ras...; Region:
                     Ras_like_GTPase; cl10444"
                     /db_xref="CDD:195960"
     misc_feature    complement(<4394..>4675)
                     /locus_tag="Calni_2073"
                     /note="Orbivirus outer capsid protein VP5; Region:
                     Orbi_VP5; pfam00901"
                     /db_xref="CDD:189762"
     gene            complement(5954..7654)
                     /locus_tag="Calni_2074"
                     /db_xref="GeneID:10004275"
     CDS             complement(5954..7654)
                     /locus_tag="Calni_2074"
                     /note="KEGG: dap:Dacet_0620 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Dynamin family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046702.1"
                     /db_xref="GI:313652024"
                     /db_xref="GeneID:10004275"
                     /translation="MKVKENMVEFLSILDSQIKSDQELHDSISSIDLNIDELKEDILQ
                     REIIVPIIGPFSAGKSSLINSFLETDYLPVGITPETSLATEIRYSENERIECIMSDNS
                     DKPDIYSLSDFEKIKEKANAYEYMVVYLNNPNLKRIQPAVLVDMPGFESPVDIHNKAI
                     LNYLGKGIFYVVVISVESGTLPRSFLNRLKGLESLQRDFEVILNKVNLKSEKDVLAIK
                     EKIEEDIKTYLNFDKEVHLVGENGGKILEKILTSLNTDELIKKMYLPDLKYKTFQVVD
                     TIETIISSMQKTVEQNDKEIKALEKEIESLIKEKDKKIREIESKHSSTNVNRILSSIE
                     REMIAQKDYLANIAVSSPDKFSKIVNDMVVNVLSVDVPNIISDIGSEIIDDVGVHLKS
                     IQNSSDLGVNIPTNWISEKATQLKDNLLFSITNKLEQYKNTARAAAVILAVTTNFIAP
                     VLELIIIALPDIVNKLLSSSIEQKQKEKAKSIIMTQIIPSLKAELRPKLLEIVNNEIK
                     KLTTNVINEYENMLRLKKDSIEQAQKNLKEKAEEISVKISKYQNIKKNIVDSYNKYLS
                     "
     misc_feature    complement(7037..7504)
                     /locus_tag="Calni_2074"
                     /note="Ras-like GTPase superfamily. The Ras-like
                     superfamily of small GTPases consists of several families
                     with an extremely high degree of structural and functional
                     similarity. The Ras superfamily is divided into at least
                     four families in eukaryotes: the Ras...; Region:
                     Ras_like_GTPase; cl10444"
                     /db_xref="CDD:195960"
     gene            7954..8061
                     /locus_tag="Calni_2075"
                     /db_xref="GeneID:10004276"
     CDS             7954..8061
                     /locus_tag="Calni_2075"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046703.1"
                     /db_xref="GI:313652025"
                     /db_xref="GeneID:10004276"
                     /translation="MRMSLKIELEFDEDELLKNKKGKIYVLLNHVPILG"
     gene            8179..8586
                     /locus_tag="Calni_2076"
                     /db_xref="GeneID:10004277"
     CDS             8179..8586
                     /locus_tag="Calni_2076"
                     /note="COGs: COG1943 Transposase and inactivated
                     derivatives;
                     InterPro IPR002686;
                     KEGG: aar:Acear_1998 transposase IS200-family protein;
                     PFAM: transposase IS200-family protein;
                     SPTR: Transposase IS200-family protein;
                     PFAM: Transposase IS200 like"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS200-family protein"
                     /protein_id="YP_004046704.1"
                     /db_xref="GI:313652026"
                     /db_xref="GeneID:10004277"
                     /translation="MSKINIKHGRTVVYNVNYHIVWSTKYRKKVLTGNIEQRLRVLMN
                     EITKDKGFEIKSMKIMPDHIHVFVTAHPKYSPSYIYKMLKGISGRKLFIEFPDLKKQS
                     WRGHLWNPSTYIETIGHISEETIKKYIEDQKKK"
     misc_feature    8215..8574
                     /locus_tag="Calni_2076"
                     /note="Transposase IS200 like; Region: Y1_Tnp; cl00848"
                     /db_xref="CDD:154036"
     gene            8586..9791
                     /locus_tag="Calni_2077"
                     /db_xref="GeneID:10004278"
     CDS             8586..9791
                     /locus_tag="Calni_2077"
                     /note="COGs: COG0675 Transposase and inactivated
                     derivatives;
                     InterPro IPR010095: IPR001959;
                     KEGG: cyc:PCC7424_2948 transposase, IS605 OrfB family;
                     PFAM: transposase IS891/IS1136/IS1341 family; transposase
                     IS605 OrfB;
                     SPTR: Transposase, IS605 OrfB family;
                     TIGRFAM: transposase, IS605 OrfB family;
                     PFAM: Helix-turn-helix domain; Putative transposase
                     DNA-binding domain; Probable transposase;
                     TIGRFAM: transposase, IS605 OrfB family, central region"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase, IS605 OrfB family"
                     /protein_id="YP_004046705.1"
                     /db_xref="GI:313652027"
                     /db_xref="GeneID:10004278"
                     /translation="MVLKAYKYRLYPTKEQAELIERHFGCCRFVWNYFLSLRKETWDK
                     EKKHLSFYEIKKLLPELKKQNPWLKEVNSQSLQEVVIELERSYQRFFKGICNFPLFKK
                     KKKSQSFSIPQHFRIESDRVYLPKFKTGIKFKKHREFTGLPKRLYITRTPSGKYFLLV
                     VCETEINVLPENKYIAGVDLGIKNFVTIARVNKDNTLIKTEKVPHPKTLQKYEKRIKR
                     LQRQLSRKQKGSKNRQKARIKLAKIWEKAKNVKYDYLHKLSSRLINENQVICLEDLNI
                     KGMIKNRKLSKNIWDSAWYEFIRQLRYKAMWYGRKIATIPLFYPSSKTCSNCGWIFSD
                     MDLSVREWECPCCGAKHDRDINASINVVKVGMEQPEFMPVEETTRVFSMRRQVVPVKQ
                     EAMHGISIP"
     misc_feature    8589..9686
                     /locus_tag="Calni_2077"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG0675"
                     /db_xref="CDD:31019"
     misc_feature    8592..8726
                     /locus_tag="Calni_2077"
                     /note="Helix-turn-helix domain; Region: HTH_OrfB_IS605;
                     pfam12323"
                     /db_xref="CDD:192986"
     misc_feature    8781..9422
                     /locus_tag="Calni_2077"
                     /note="Probable transposase; Region: OrfB_IS605;
                     pfam01385"
                     /db_xref="CDD:189964"
     misc_feature    9465..9674
                     /locus_tag="Calni_2077"
                     /note="Putative transposase DNA-binding domain; Region:
                     OrfB_Zn_ribbon; pfam07282"
                     /db_xref="CDD:115907"
     gene            10100..10339
                     /locus_tag="Calni_2078"
                     /db_xref="GeneID:10004279"
     CDS             10100..10339
                     /locus_tag="Calni_2078"
                     /note="KEGG: fps:FP2181 hypothetical protein;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046706.1"
                     /db_xref="GI:313652028"
                     /db_xref="GeneID:10004279"
                     /translation="MPKYYCKYCGASASSVSSLTAGSCSRNPVKGGKHVLYEGSEKSQ
                     YVCKYCGIKASTISTLTAGTCYRHPNKGGRHEPML"
     gene            11137..12675
                     /locus_tag="Calni_2079"
                     /db_xref="GeneID:10004280"
     CDS             11137..12675
                     /locus_tag="Calni_2079"
                     /note="InterPro IPR018631: IPR012547;
                     KEGG: ddf:DEFDS_0353 hypothetical protein;
                     PFAM: AAA-ATPase-like; protein of unknown function
                     DUF1703;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Protein of unknown function (DUF1703); Predicted
                     AAA-ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA-ATPase"
                     /protein_id="YP_004046707.1"
                     /db_xref="GI:313652029"
                     /db_xref="GeneID:10004280"
                     /translation="MKKLPIGIQTFSKIREEGYIYIDKTEEAFELVNNFTYVFLSRPR
                     RFGKSLFVDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLTTLERVEDRA
                     IDIFKTNQRLLGIECENNKNPSSCFNELIQKAYEKYNQKVVILIDEYDKPILDVIENV
                     EQAKINRGFLRNLYSIIKDNDAYIRFAFLTGVSKFSKASIFSGLNMLTDISLNPKYGN
                     ICGYTQRDIETSFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPFDILQFISNGLVFDNY
                     WFETGTPSFLIKLLKERRYFLPNFSNIVVDKKLLSSFDVENIDLEVILFQSGYLTIEK
                     VIQTPRSIGYKLKIPNLEVQISLNDYILRYLFNYRESNDIQNQSYDAFYNGELDVIRD
                     NLTTLFSSIPYTNYTNNELKLYEGFYASVVYSYLASLGVDLIGEDVTNKGRIDLTVFV
                     SDKIYIMEFKVDGAKGEALSQIKQKNYAQKYMDRGKDIYLVGIEFSSSERNIVNFEWE
                     KLER"
     misc_feature    11149..11943
                     /locus_tag="Calni_2079"
                     /note="Predicted AAA-ATPase; Region: AAA-ATPase_like;
                     pfam09820"
                     /db_xref="CDD:192394"
     misc_feature    12373..12645
                     /locus_tag="Calni_2079"
                     /note="Protein of unknown function (DUF1703); Region:
                     DUF1703; pfam08011"
                     /db_xref="CDD:149218"
     gene            12894..14942
                     /locus_tag="Calni_2080"
                     /db_xref="GeneID:10004281"
     CDS             12894..14942
                     /locus_tag="Calni_2080"
                     /note="InterPro IPR006626;
                     KEGG: cbr:CBG18961 C. briggsae CBR-DRE-1 protein;
                     SPTR: Heat shock protein 70"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046708.1"
                     /db_xref="GI:313652030"
                     /db_xref="GeneID:10004281"
                     /translation="MFNLGRIVIGINIKDGDSVKCIKEVNEFKKYFKDEYLIYILKAY
                     ESGVLKQFFYGHGKDEISEMLEQAKLNGKPQFEVLNDLAKILGISEIKSESVLKNMRI
                     FDKEILLDNLLENGGEIYLMADTYDFKFQNSKLLKNIFLRGSGLNKTLINIGGELYLD
                     DDVEMIIENFDLKIIDSLKIENGKVIFRNVSIDGGSIDLTSTFAELDNVNVSSTINSY
                     SSNLIVSSSKIFGGESLNLINSQSEIKNSQIYKMNGNGIDAKSSNVIVDNSEIYENLK
                     NGIVIKESSTLTLTSSNIYKNGRKDEWYHQIWVENSYAEISDSRIFESKGGAGIYGVF
                     AKIVIKNSEIYENSGRGISIRESSMLILMSSNIYKNGRKDEWYHQIWVENSYAEISDS
                     KIHESKGGVGIYGNSAKIVIKNSEVYGNTGNGIGMIDSSTLTLTSSNIYENGMKDKSY
                     HQIYVEKSDAEISDSRIFESKGGSGIYGESAKLVIKNSEVYENLGNGINIKESSTLTL
                     ISSNIYKNGTEGKSYPQIWVEKSDAEVSDSRIFESKGRSGIYGESGKLVIKNSEVYEN
                     LWYGIEIKESSTLTLTSSNIYKNRFTQIYIEKSDAEISDSKIYENRSEGDGIYCISSK
                     IVIKNSEVFENQGVGINIRRDSDAYLYSVVTYKNKIGLKHYPSISKENCDFKDGYQYR
                     "
     misc_feature    <13845..14228
                     /locus_tag="Calni_2080"
                     /note="Pectate lyase superfamily protein; Region:
                     Pectate_lyase_3; pfam12708"
                     /db_xref="CDD:193184"
     misc_feature    14052..>14804
                     /locus_tag="Calni_2080"
                     /note="Nitrous oxidase accessory protein [Inorganic ion
                     transport and metabolism]; Region: NosD; COG3420"
                     /db_xref="CDD:33226"
     gene            14982..16511
                     /locus_tag="Calni_2081"
                     /db_xref="GeneID:10004282"
     CDS             14982..16511
                     /locus_tag="Calni_2081"
                     /note="COGs: COG0464 ATPase of the AAA+ class;
                     InterPro IPR003593: IPR003959;
                     KEGG: alv:Alvin_1450 AAA ATPase central domain protein;
                     PFAM: AAA ATPase central domain protein;
                     SMART: AAA ATPase;
                     SPTR: ATPase, AAA family;
                     PFAM: ATPase family associated with various cellular
                     activities (AAA)"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA ATPase central domain protein"
                     /protein_id="YP_004046709.1"
                     /db_xref="GI:313652031"
                     /db_xref="GeneID:10004282"
                     /translation="MMDYRRSWEKIKEKILTHINCDDYKLFYVSTIEETKVLKMLGEI
                     ADQKDVFLYTYDIASGLKCDKDKRIKNLSDDFKKDLSSVIEWVEGQKKGYLVFVNINQ
                     HIEQNYFLIRKIKNFVNSIIENNYYIKIFMVSQFVRIPDELQHEACFIDFPLPTRDEI
                     KDIVDNFFKIIQNEPTKEFREQIIDSLLGLREIDIVNALKFALYSGALDKGDVHTIID
                     IKSQIIKKESLLEFIKITENIENVGGMKNLKDWVLQKKKVIFNLSDAYNYGLENPKGI
                     LLFGMPGCGKSLVAKVISNEWKLPLLRLDIGMILGPYVGQSEENIRRAIKIAESIAPV
                     VLWIDELEKAFAGISDGNSGGSDVMKRVFGSFLTWMQEKTKPVFVVATANDISAIPPE
                     FLRKGRFDEIFYVDLPNKDGINEILKIHLRKRNKESWHEFFQEFMPKLSGFSGADIEA
                     LVKEIIELSFVNNMTNKKDDISKFIEKTIGDFKPITATMNSKIENLRNKMKEINAKSV
                     D"
     misc_feature    <15309..16475
                     /locus_tag="Calni_2081"
                     /note="Ycf46; Provisional; Region: ycf46; CHL00195"
                     /db_xref="CDD:177094"
     misc_feature    15789..16202
                     /locus_tag="Calni_2081"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes...; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    15819..15842
                     /locus_tag="Calni_2081"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    order(15822..15845,15996..15998,16131..16133)
                     /locus_tag="Calni_2081"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    15984..16001
                     /locus_tag="Calni_2081"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    16173..16175
                     /locus_tag="Calni_2081"
                     /note="arginine finger; other site"
                     /db_xref="CDD:99707"
     gene            16526..16840
                     /locus_tag="Calni_2082"
                     /db_xref="GeneID:10004283"
     CDS             16526..16840
                     /locus_tag="Calni_2082"
                     /note="KEGG: pfa:PF13_0047 conserved Plasmodium protein,
                     unknown function;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046710.1"
                     /db_xref="GI:313652032"
                     /db_xref="GeneID:10004283"
                     /translation="MKEISPEFIKEISRFADEITDEFMKNQDKDPLEFSIQLIMKYKD
                     ISYEEAKDYLKRIIEGILRYRNMDENISISEITKGEIKDEQLAEITEDLVDISKKMLE
                     SE"
     gene            16860..17300
                     /locus_tag="Calni_2083"
                     /db_xref="GeneID:10004284"
     CDS             16860..17300
                     /locus_tag="Calni_2083"
                     /note="KEGG: msi:Msm_0335 glutamyl-tRNA(Gln)
                     amidotransferase subunit E;
                     SPTR: Methyl-accepting chemotaxis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046711.1"
                     /db_xref="GI:313652033"
                     /db_xref="GeneID:10004284"
                     /translation="MNDKNEKNFTLEDIINSIALVRAQEAGLLGNEQIKPEDAGILGA
                     LSTDLLDIFNKVLKNEISKEKASIEIKEHTSKAFKALVSNVYDIATNFAVSATKKIPI
                     IGPVLSTTIKVVAERAKKPVVNKIVEAGMKIAKSVEKLFDSLFS"
     gene            17742..18872
                     /locus_tag="Calni_2084"
                     /db_xref="GeneID:10004285"
     CDS             17742..18872
                     /locus_tag="Calni_2084"
                     /note="InterPro IPR018631;
                     KEGG: ddf:DEFDS_1269 hypothetical protein;
                     PFAM: AAA-ATPase-like;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Predicted AAA-ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA-ATPase"
                     /protein_id="YP_004046712.1"
                     /db_xref="GI:313652034"
                     /db_xref="GeneID:10004285"
                     /translation="MKKLPIGIQTFSKIREEGYIYIDKTEEAFELVNNFTYVFLSRPR
                     RFGKSLFLDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLQTLESVKRVA
                     LYKFKSNQENLGISCDNTTDPGSYFSDLIHKAYKKYGKKVVILVDEYDKPILDVIDKI
                     DQVKIYMEFLKGLYSIIEDNEVYIRFAFLTGVSKFSKSCIFSDPDRLTDISLSPKFGN
                     ICSCTQREIETTFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPSDILNFIKNECKFDNY
                     WFETGTPSFLIKLIKERKYFIPNFANLIVDDKVLFSSDIENLGIEAILFQSGYLTIEK
                     AIQTPRGIEYKLKIPNFEVELSLNNYILRYLSGFEDSAANTM"
     misc_feature    17754..18548
                     /locus_tag="Calni_2084"
                     /note="Predicted AAA-ATPase; Region: AAA-ATPase_like;
                     pfam09820"
                     /db_xref="CDD:192394"
     gene            complement(19049..19462)
                     /locus_tag="Calni_2085"
                     /pseudo
                     /db_xref="GeneID:10004286"
     gene            complement(19472..19669)
                     /locus_tag="Calni_2086"
                     /db_xref="GeneID:10004287"
     CDS             complement(19472..19669)
                     /locus_tag="Calni_2086"
                     /note="KEGG: ddf:DEFDS_P065 hypothetical protein;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046713.1"
                     /db_xref="GI:313652035"
                     /db_xref="GeneID:10004287"
                     /translation="MEEKEKSYRVNVNEVNMKRITIIKALFSEETETLSDKEAINYIV
                     NKAIENYFKSEEIQNKLKNLQ"
     gene            19934..20890
                     /locus_tag="Calni_2087"
                     /db_xref="GeneID:10004288"
     CDS             19934..20890
                     /locus_tag="Calni_2087"
                     /note="COGs: COG4974 Site-specific recombinase XerD;
                     InterPro IPR002104;
                     KEGG: ddf:DEFDS_P066 site-specific recombinase, phage
                     integrase family;
                     PFAM: integrase family protein;
                     SPTR: Site-specific recombinase, phage integrase family;
                     PFAM: Phage integrase family"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase family protein"
                     /protein_id="YP_004046714.1"
                     /db_xref="GI:313652036"
                     /db_xref="GeneID:10004288"
                     /translation="MTPKPAENPIPILQKHKENFLNELKSQNYSKNTITAYSQEIDYF
                     IEFFRGFQDDMEIIDINRPFIQQSLIFREENSKTGKIATNTKKMYLKALYQFFVYLTD
                     AMNGIKDFTTLFSKIKIKAETRQKEYLNEVEIKRLLNYINVKKNKRMSFITCRNILLI
                     KILLYTGMRASEVINIKLSDITTYEQDKNIIQIRIIGKGNKEGFCYIDHLKISEELED
                     TLLFRKRLNITSEYLFTTKTGRQMTRQEAFLATANILKKAGINKKGLHLFRHTLGFHL
                     AQKGVRIEDIQEILRHSNINTTRIYVQRREADKINGIKKIDY"
     misc_feature    19985..20836
                     /locus_tag="Calni_2087"
                     /note="DNA breaking-rejoining enzymes, C-terminal
                     catalytic domain. The DNA breaking-rejoining enzyme
                     superfamily includes type IB topoisomerases and tyrosine
                     recombinases that share the same fold in their catalytic
                     domain containing six conserved active site...; Region:
                     DNA_BRE_C; cl00213"
                     /db_xref="CDD:193712"
     misc_feature    19985..20836
                     /locus_tag="Calni_2087"
                     /note="Site-specific recombinase XerD [DNA replication,
                     recombination, and repair]; Region: XerD; COG4974"
                     /db_xref="CDD:34580"
     misc_feature    order(20438..20443,20525..20527,20726..20728,20729..20731,
                     20834..20836)
                     /locus_tag="Calni_2087"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:29495"
     misc_feature    order(20438..20440,20525..20527,20729..20731,20738..20740,
                     20807..20809,20834..20836)
                     /locus_tag="Calni_2087"
                     /note="Int/Topo IB signature motif; other site"
                     /db_xref="CDD:29495"
     misc_feature    order(20438..20440,20729..20731,20738..20740,20807..20809,
                     20834..20836)
                     /locus_tag="Calni_2087"
                     /note="active site"
                     /db_xref="CDD:29495"
     gene            21039..22581
                     /locus_tag="Calni_2088"
                     /pseudo
                     /db_xref="GeneID:10004289"
     gene            22734..24029
                     /locus_tag="Calni_2089"
                     /db_xref="GeneID:10004290"
     CDS             22734..24029
                     /locus_tag="Calni_2089"
                     /note="COGs: COG1373 ATPase (AAA+ superfamily);
                     KEGG: dap:Dacet_1071 ATPase;
                     SPTR: ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="YP_004046715.1"
                     /db_xref="GI:313652037"
                     /db_xref="GeneID:10004290"
                     /translation="MRNDKIKDIFKRVIIDFIESSPKKVMARDYNIPLNSKKIVSLVG
                     VRRSGKSSILFDMINRLREKLPIENIIYINFEDDRLYPLDLKSLDFLLEAYYELYPSK
                     RDQKIYLFLDEIQAVQDWELYVRRIYDTLDVQIFITGSSAKLLSTDIATSLRGRTITY
                     EIFPFSFKEYLRYKNIDVNLHSSKSLSFIKNALANYIINGGFAETIDEDEQISRKILS
                     DYLELIVYKDIIDRYNIQNRSLLKVLNKYCFTNIATLVSFNKLYNEFKSQGYKLGKDT
                     IFQYISHLEDAYAIFTLPIYRNSIKEEQRNPKKIYAIDNGFKKIYDYAISEDISKLYE
                     NVVYLHLRSQTKNIYYFKQKHEVDFYAKFHDKEMLINVSVDIKDQKTRQRELEGLKEA
                     MEYFNLKQSYLITKDEESTEVIDSRKIYIIPLYKWLLLY"
     misc_feature    22755..24026
                     /locus_tag="Calni_2089"
                     /note="Predicted ATPase (AAA+ superfamily) [General
                     function prediction only]; Region: COG1373"
                     /db_xref="CDD:31564"
     gene            complement(24212..24952)
                     /locus_tag="Calni_2090"
                     /db_xref="GeneID:10004291"
     CDS             complement(24212..24952)
                     /locus_tag="Calni_2090"
                     /note="COGs: COG0790 FOG: TPR repeat SEL1 subfamily;
                     InterPro IPR006597;
                     KEGG: wsu:WS0385 hypothetical protein;
                     PFAM: Sel1 domain protein repeat-containing protein;
                     SPTR: Sel1 repeat-containing domain protein;
                     PFAM: Sel1 repeat"
                     /codon_start=1
                     /transl_table=11
                     /product="Sel1 domain protein repeat-containing protein"
                     /protein_id="YP_004046716.1"
                     /db_xref="GI:313652038"
                     /db_xref="GeneID:10004291"
                     /translation="MSKKLNFLLFGLIFLAICINSWAGLVEDGLKLLDQKKYKEAFQK
                     FKKACDGGDAKGCFILGVMYDNGQGVRQDYSKAVEFYQKACDGGEALGCFNLGFMYYN
                     GQGVGQDYSKAVEFYQKACDGGDAWGCYNLGVQYEKGQGVGQDNFKAVEFYQKACDGG
                     YALGCNNLGVMYAKGQGVGQDYFKAAEFYQKACDGGEAKGCYNLGVMYYEGQGVRQDY
                     FRAKELFGKACDMKLQKGCDAYKELNKK"
     misc_feature    complement(24689..24793)
                     /locus_tag="Calni_2090"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:194424"
     misc_feature    complement(24578..24685)
                     /locus_tag="Calni_2090"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:194424"
     misc_feature    complement(24470..24571)
                     /locus_tag="Calni_2090"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:194424"
     misc_feature    complement(24365..24469)
                     /locus_tag="Calni_2090"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:194424"
     misc_feature    complement(24257..24361)
                     /locus_tag="Calni_2090"
                     /note="Sel1 repeat; Region: Sel1; cl02723"
                     /db_xref="CDD:194424"
     gene            complement(25259..26230)
                     /locus_tag="Calni_2091"
                     /db_xref="GeneID:10004292"
     CDS             complement(25259..26230)
                     /locus_tag="Calni_2091"
                     /note="InterPro IPR004437: IPR003115;
                     KEGG: ddf:DEFDS_P213 hypothetical protein;
                     PFAM: ParB domain protein nuclease;
                     SMART: ParB domain protein nuclease;
                     SPTR: Putative uncharacterized protein;
                     TIGRFAM: parB-like partition protein;
                     PFAM: ParB-like nuclease domain;
                     TIGRFAM: ParB-like partition proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="parB-like partition protein"
                     /protein_id="YP_004046717.1"
                     /db_xref="GI:313652039"
                     /db_xref="GeneID:10004292"
                     /translation="MKKDNMFNKSRATNILSGDLYQTNMVKVPIDKIVADEQIRKKFD
                     EKGIEELAESIKKYGLINPILVELDDKTQMFKIIAGERRYLACKKLGINKITVHVLGS
                     RSENEKKIMQFEENVRREDLTLYEKSTAIFELMQDFLAEKVGIDKSIDNILSELIKIN
                     DGKSSLNLKVATIKEDIEKYFGMSLMSIIYLLYPLSFNIDHIKYMHEANIPITIFLLF
                     ISVKNDKEFIEECLDKYLEGKINAEKIKRLVSGKKDTNQKTEVKKRIRILQNIKTAVN
                     NFEKLKRTLEDENIIIREKDKVRNEIERLKRYINEIELKLKEDDNVV"
     misc_feature    complement(25880..26155)
                     /locus_tag="Calni_2091"
                     /note="ParB-like nuclease domain; Region: ParBc; cl02129"
                     /db_xref="CDD:154762"
     gene            complement(26217..27122)
                     /locus_tag="Calni_2092"
                     /db_xref="GeneID:10004293"
     CDS             complement(26217..27122)
                     /locus_tag="Calni_2092"
                     /note="COGs: COG1192 ATPase involved in chromosome
                     partitioning;
                     KEGG: ddf:DEFDS_P212 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046718.1"
                     /db_xref="GI:313652040"
                     /db_xref="GeneID:10004293"
                     /translation="MKTSIYIGNVKGGTGKTTLALMLGEYYRQIKNKKVLMIDLDYQQ
                     VNTCQYFAEQTLLADMRHKNLYTLLDYIINNINTVVDKYSETRMELEKKFLDSLIPFK
                     YNDENDELQIDYNFAVIASDIEFGEISNKMSKTIPLSHLVFKVLLEIAYKYYDVIIID
                     TPPGVDFLPSQFALMSVENLLTVTDVGEFGLTGLNKMIATFKSSSLINKNLNFVGVVI
                     NKVKQNSYDNDFVAFVKESYGDYIIDTVLNDYVDYKQALLERKYILTDYKQVRGQKSI
                     ENAKKLLNEIDSRVKWIRWDGDEKR"
     misc_feature    complement(26256..27122)
                     /locus_tag="Calni_2092"
                     /note="ATPases involved in chromosome partitioning [Cell
                     division and chromosome partitioning]; Region: Soj;
                     COG1192"
                     /db_xref="CDD:31385"
     misc_feature    complement(<26994..27110)
                     /locus_tag="Calni_2092"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following...; Region: ParA;
                     cd02042"
                     /db_xref="CDD:73302"
     misc_feature    complement(27072..27092)
                     /locus_tag="Calni_2092"
                     /note="P-loop; other site"
                     /db_xref="CDD:73302"
     misc_feature    complement(27072..27074)
                     /locus_tag="Calni_2092"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:73302"
     misc_feature    complement(26466..>26711)
                     /locus_tag="Calni_2092"
                     /note="ParA and ParB of Caulobacter crescentus belong to a
                     conserved family of bacterial proteins implicated in
                     chromosome segregation. ParB binds to DNA sequences
                     adjacent to the origin of replication and localizes to
                     opposite cell poles shortly following...; Region: ParA;
                     cd02042"
                     /db_xref="CDD:73302"
     misc_feature    complement(26643..26645)
                     /locus_tag="Calni_2092"
                     /note="Magnesium ion binding site [ion binding]; other
                     site"
                     /db_xref="CDD:73302"
     gene            complement(27132..28589)
                     /locus_tag="Calni_2093"
                     /db_xref="GeneID:10004294"
     CDS             complement(27132..28589)
                     /locus_tag="Calni_2093"
                     /note="COGs: COG0593 ATPase involved in DNA replication
                     initiation;
                     InterPro IPR003593: IPR020591: IPR013317;
                     KEGG: ddf:DEFDS_P211 hypothetical protein;
                     PFAM: Chromosomal replication initiator DnaA;
                     SMART: AAA ATPase;
                     SPTR: Chromosomal replication initiator protein dnaA;
                     PFAM: Bacterial dnaA protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Chromosomal replication initiator DnaA"
                     /protein_id="YP_004046719.1"
                     /db_xref="GI:313652041"
                     /db_xref="GeneID:10004294"
                     /translation="MGDKMEFSEYIEYIQNEIKKDGETYNEKYGILFIIGILSTKFTL
                     ENKKIIATASSFIIEKLKNEKEKMMDLLKDVIIAYDIEDIIFQAEKIINTIKTEDGFI
                     EKEYTLPKNIIISQADSFNTKYSFDNYLVDSTNHSAYMTMKSVAEGNYGGKIITLYGP
                     TGVGKTHLVSAMLNAFSEKYEGKSAYYFVKSYWVELIKKYSSMRQLEIFLREINKADI
                     IAIDDLSFICDTNRPVYIQLIYDLINLRVVKEKVTVITTPVQPDYIKLNKELADNATG
                     SYFELNKNGDVVLGSPFVSRLKSNMIYISEPSFNLKLLFAKRVLKYSLQIDFEELNKT
                     SQDILAIIIDSHRGDFRYINGIMNELLEKYTLHNNINSAIMELADNMGLKEKLKINNQ
                     NHRINYLVERMCEKFSIRLSEIQGRLKKGSELKIIRNAIIYVLNKYHDFSFQAISEVF
                     KISKVSAHSGYGEFEEEIEKNNEKHKEVLDIIIRV"
     misc_feature    complement(27237..28451)
                     /locus_tag="Calni_2093"
                     /note="ATPase involved in DNA replication initiation [DNA
                     replication, recombination, and repair]; Region: DnaA;
                     COG0593"
                     /db_xref="CDD:30938"
     misc_feature    complement(27774..28187)
                     /locus_tag="Calni_2093"
                     /note="The AAA+ (ATPases Associated with a wide variety of
                     cellular Activities) superfamily represents an ancient
                     group of ATPases belonging to the ASCE (for additional
                     strand, catalytic E) division of the P-loop NTPase fold.
                     The ASCE division also includes...; Region: AAA; cd00009"
                     /db_xref="CDD:99707"
     misc_feature    complement(28092..28115)
                     /locus_tag="Calni_2093"
                     /note="Walker A motif; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(order(27813..27815,27924..27926,28089..28112))
                     /locus_tag="Calni_2093"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:99707"
     misc_feature    complement(27921..27938)
                     /locus_tag="Calni_2093"
                     /note="Walker B motif; other site"
                     /db_xref="CDD:99707"
     gene            28981..29439
                     /locus_tag="Calni_2094"
                     /db_xref="GeneID:10004295"
     CDS             28981..29439
                     /locus_tag="Calni_2094"
                     /note="COGs: COG1943 Transposase and inactivated
                     derivatives;
                     InterPro IPR002686;
                     KEGG: cob:COB47_2235 transposase IS200-family protein;
                     PFAM: transposase IS200-family protein;
                     SPTR: Transposase IS200-family protein;
                     PFAM: Transposase IS200 like"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase IS200-family protein"
                     /protein_id="YP_004046720.1"
                     /db_xref="GI:313652042"
                     /db_xref="GeneID:10004295"
                     /translation="MTNNQFRIILFLINKVKLDTNKHSVYLLYYHLVLVVKYRKKVID
                     DRISNRLKEIFEYIQPNYNITLIEWSHDEDHVHILFKATPTSSLAKFINAYKSASSRL
                     IKKEFPKIKEKLWDKYFWSRSYCLLTSGGAPVDVIRKYIENQGKKNAKSV"
     misc_feature    29107..29412
                     /locus_tag="Calni_2094"
                     /note="Transposase IS200 like; Region: Y1_Tnp; cl00848"
                     /db_xref="CDD:154036"
     gene            29423..30631
                     /locus_tag="Calni_2095"
                     /db_xref="GeneID:10004296"
     CDS             29423..30631
                     /locus_tag="Calni_2095"
                     /note="COGs: COG0675 Transposase and inactivated
                     derivatives;
                     InterPro IPR010095: IPR001959;
                     KEGG: sul:SYO3AOP1_1391 transposase, IS605 OrfB family;
                     PFAM: transposase IS891/IS1136/IS1341 family; transposase
                     IS605 OrfB;
                     SPTR: Transposase, IS605 OrfB family;
                     TIGRFAM: transposase, IS605 OrfB family;
                     PFAM: Helix-turn-helix domain; Putative transposase
                     DNA-binding domain; Probable transposase;
                     TIGRFAM: transposase, IS605 OrfB family, central region"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase, IS605 OrfB family"
                     /protein_id="YP_004046721.1"
                     /db_xref="GI:313652043"
                     /db_xref="GeneID:10004296"
                     /translation="MLKAYRYRIYPDKEQEEFFTKTFGACRFVWNKMLEEKLKFLDRK
                     EKIPIITPANYKKEFLFLKEVDSLALANIQLQNEKAFRDYFRNPKHFKLPKFKNKKGK
                     QSYTTNNVKVDFEKGLLFLPKIKSGIKACFHRTFTGKIKSATITKTKTGKYFVSILVE
                     IEQQCNIQPPKNEVCGIDLGLKDFAIITNEKKETIKIPSPKHLVKAEKRLKRLQNQLS
                     KKQKGSKNREKHRVRLSKLHEHVSAARNDFLHKLSFAIIRDNQTIVVEDLNVKGLSQS
                     NLSKSVLDSSWGKFLNYLKYKAEWYGRTIIVVDKFYPSSKTCSVCNFINHRLTLKNRH
                     WTCEECGTYHDRDINASVNLMFYGMKKVGMEQPEFTPVDCALAAELKQFRSTSHHRMK
                     QEATTSISGW"
     misc_feature    29423..30523
                     /locus_tag="Calni_2095"
                     /note="Transposase and inactivated derivatives [DNA
                     replication, recombination, and repair]; Region: COG0675"
                     /db_xref="CDD:31019"
     misc_feature    29423..>29533
                     /locus_tag="Calni_2095"
                     /note="Helix-turn-helix domain; Region: HTH_OrfB_IS605;
                     pfam12323"
                     /db_xref="CDD:192986"
     misc_feature    29603..30247
                     /locus_tag="Calni_2095"
                     /note="Probable transposase; Region: OrfB_IS605;
                     pfam01385"
                     /db_xref="CDD:189964"
     misc_feature    30281..30487
                     /locus_tag="Calni_2095"
                     /note="Putative transposase DNA-binding domain; Region:
                     OrfB_Zn_ribbon; pfam07282"
                     /db_xref="CDD:115907"
     gene            30991..31239
                     /locus_tag="Calni_2096"
                     /db_xref="GeneID:10004297"
     CDS             30991..31239
                     /locus_tag="Calni_2096"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046722.1"
                     /db_xref="GI:313652044"
                     /db_xref="GeneID:10004297"
                     /translation="MEKILFPLFVNIVIYCMAKKRYLLAISCKFKYEFLIVKYEFWGV
                     KCEVLVVKTKNMASGVTFHSGGLDHGKFYFLSCESPWT"
     gene            31510..32616
                     /locus_tag="Calni_2097"
                     /db_xref="GeneID:10004298"
     CDS             31510..32616
                     /locus_tag="Calni_2097"
                     /note="COGs: COG3328 Transposase and inactivated
                     derivatives;
                     InterPro IPR001207;
                     KEGG: nth:Nther_2336 transposase mutator type;
                     PFAM: transposase mutator type;
                     SPTR: Transposase mutator type;
                     PFAM: Transposase, Mutator family"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase mutator type"
                     /protein_id="YP_004046723.1"
                     /db_xref="GI:313652045"
                     /db_xref="GeneID:10004298"
                     /translation="MDNIIINELSKYFKSMIQEIMLSEREKYLKEHSETRGNGYYIRT
                     PKTILGDMELEIPRTRDGNFKPSIIPERKRVTFMLDDVIRALFTAGLSSRKTGEVIRN
                     LMGTSVSASFVSSNLEISEEVISKFMNRELTENYPVIYIDATYISLKRDTVSKESVYV
                     VLGLSTDGRREILTYCLPGGDEKSSVWRDIFINLTNRGLRGVKMVISDDLPGIGEVIK
                     EVFPNADHQLCWFHLKKNIKNKVRKSDFDEILKELEYVFESNNEDEAKSRLHAFINKW
                     SKLYRYFNNLRDKINSYCYFFKFHPKLRSYFSTTNWLERCFKELKDNIRIRGYFHSEE
                     SANKFLYLFFSDKSLKYHERKLRYSNIIEETLNG"
     misc_feature    31549..32550
                     /locus_tag="Calni_2097"
                     /note="Transposase, Mutator family; Region:
                     Transposase_mut; pfam00872"
                     /db_xref="CDD:109910"
     misc_feature    31936..32223
                     /locus_tag="Calni_2097"
                     /note="MULE transposase domain; Region: MULE; pfam10551"
                     /db_xref="CDD:192624"
     gene            32609..32782
                     /locus_tag="Calni_2098"
                     /db_xref="GeneID:10004299"
     CDS             32609..32782
                     /locus_tag="Calni_2098"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046724.1"
                     /db_xref="GI:313652046"
                     /db_xref="GeneID:10004299"
                     /translation="MDKNASRVMVDTIKLTLPGVVIYFKYFGNLFIIILSILKSSFER
                     FFILFVVDKYCNS"
     repeat_region   33042..33333
                     /note="CRISPR"
     gene            complement(33539..33736)
                     /locus_tag="Calni_2099"
                     /db_xref="GeneID:10004300"
     CDS             complement(33539..33736)
                     /locus_tag="Calni_2099"
                     /note="KEGG: xla:380019 ADP-ribosylation factor GTPase
                     activating protein 3;
                     SPTR: Singapore isolate B (sub-type 7) whole genome
                     shotgun sequence assembly, scaffold_0"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylation factor GTPase activating
                     protein 3"
                     /protein_id="YP_004046725.1"
                     /db_xref="GI:313652047"
                     /db_xref="GeneID:10004300"
                     /translation="MAVKKSKKSSNEQTSQEQAKEPQNEERITFCGSVLLTDSEIESL
                     LQDLRMSYKILDMLESKQTQD"
     gene            34105..34971
                     /locus_tag="Calni_2100"
                     /db_xref="GeneID:10004301"
     CDS             34105..34971
                     /locus_tag="Calni_2100"
                     /note="COGs: COG0863 DNA modification methylase;
                     InterPro IPR001091: IPR017985: IPR018312: IPR002941;
                     KEGG: cyc:PCC7424_4192 DNA methylase N-4/N-6 domain
                     protein;
                     PFAM: DNA methylase N-4/N-6 domain protein;
                     SPTR: DNA methylase N-4/N-6 domain protein;
                     PFAM: DNA methylase"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase N-4/N-6 domain protein"
                     /protein_id="YP_004046726.1"
                     /db_xref="GI:313652048"
                     /db_xref="GeneID:10004301"
                     /translation="MLSKVYKCPNHTEYQSKNVNNEDIFNYLIEKLKAKTILHHKRAI
                     LLKGDVLNNNYFENDIFDLIVTSPPYNVDIKYNTHKDNISYEEYLQFSEAWLSNCYKW
                     SKKQARLCLNIPLDKNKGGQRSVGADLTILAQKVGWKYHSTIIWNEGNISRRTAWGSW
                     LSASAPYVIAPVELIVILYKEEWKKTQGTRISDISKDEFMQWTNGLWTFNGESKKRIG
                     HPAPFPLELPYRCIKLFSFVQDIVFDPFAGSGTTLIAANNTNRYSIGLEIDSSYCELS
                     KQRVLQESEMLF"
     misc_feature    34285..34938
                     /locus_tag="Calni_2100"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy)...; Region:
                     AdoMet_MTases; cl12011"
                     /db_xref="CDD:196296"
     gene            34987..35571
                     /locus_tag="Calni_2101"
                     /db_xref="GeneID:10004302"
     CDS             34987..35571
                     /locus_tag="Calni_2101"
                     /note="InterPro IPR003615: IPR002711;
                     KEGG: ele:Elen_0844 HNH endonuclease;
                     PFAM: HNH endonuclease;
                     SMART: HNH nuclease;
                     SPTR: HNH endonuclease domain protein;
                     PFAM: HNH endonuclease"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="YP_004046727.1"
                     /db_xref="GI:313652049"
                     /db_xref="GeneID:10004302"
                     /translation="MVKEKTITDLIIEFFKKHPKEDMPHGPVVDWVEEQYSKLYNRKP
                     RDTWRSIRRLHQEGFLIKVKKGIYRYDPDLVADKHLEEFSQELKNQILKRDNYKCVIC
                     GRTAKEGYELHIDHILPKDKGGKATLDNGQTLCSICNFRKKNYNQTESGKRMFIRLLK
                     IAKKIGDIETQKFCEEILKIYEKYNINGHIEWDD"
     misc_feature    35281..35412
                     /locus_tag="Calni_2101"
                     /note="HNH nucleases; HNH endonuclease signature which is
                     found in viral, prokaryotic, and eukaryotic proteins. The
                     alignment includes members of the large group of homing
                     endonucleases, yeast intron 1 protein, MutS, as well as
                     bacterial colicins, pyocins...; Region: HNHc; cl00083"
                     /db_xref="CDD:193649"
     gene            complement(36017..36358)
                     /locus_tag="Calni_2102"
                     /db_xref="GeneID:10004303"
     CDS             complement(36017..36358)
                     /locus_tag="Calni_2102"
                     /note="InterPro IPR001173;
                     KEGG: ant:Arnit_2325 family 2 glycosyl transferase;
                     PFAM: glycosyl transferase family 2;
                     SPTR: Glycosyl transferase family 2;
                     PFAM: Glycosyl transferase family 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="YP_004046728.1"
                     /db_xref="GI:313652050"
                     /db_xref="GeneID:10004303"
                     /translation="MFSCLIPAYNENNAVIEAICYKLLKYDIKEIIIIDDGSVNPVEL
                     TINSNLIKIIRKEKNSGKGNAIATDLKIKNNFFLSTMFIICRKKDQNFQRPCNLICVN
                     PDSSIYKINHL"
     gene            complement(36436..36624)
                     /locus_tag="Calni_2103"
                     /db_xref="GeneID:10004304"
     CDS             complement(36436..36624)
                     /locus_tag="Calni_2103"
                     /note="KEGG: pyo:PY01987 CCAAT-box DNA binding protein
                     subunit B;
                     SPTR: CCAAT-box DNA binding protein subunit B, putative"
                     /codon_start=1
                     /transl_table=11
                     /product="CCAAT-box DNA binding protein subunit B"
                     /protein_id="YP_004046729.1"
                     /db_xref="GI:313652051"
                     /db_xref="GeneID:10004304"
                     /translation="MRHVNKNHFVEKLLEKRIERDGFYYTKKKLRLEQIIGIIGTFFM
                     AICIPLFLYFVFSKINSF"
     gene            complement(36643..36807)
                     /locus_tag="Calni_2104"
                     /db_xref="GeneID:10004305"
     CDS             complement(36643..36807)
                     /locus_tag="Calni_2104"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046730.1"
                     /db_xref="GI:313652052"
                     /db_xref="GeneID:10004305"
                     /translation="MENGEIKKRKIRPGSLEDIVEYKSKLELQAYKFTLFAIILGFVL
                     GFLLFSIGKK"
     gene            37012..37248
                     /locus_tag="Calni_2105"
                     /db_xref="GeneID:10004306"
     CDS             37012..37248
                     /locus_tag="Calni_2105"
                     /note="KEGG: ecp:ECP_3803 hypothetical protein;
                     SPTR: Putative uncharacterized protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_004046731.1"
                     /db_xref="GI:313652053"
                     /db_xref="GeneID:10004306"
                     /translation="MIYEIAENVKRKILILTQNLNDYITRPQQKYLIEMVSGVFATKS
                     LNLTSIAGYLNERCGVKHPLKRLQRNTLSFQTSG"
     gene            37428..38966
                     /locus_tag="Calni_2106"
                     /db_xref="GeneID:10004307"
     CDS             37428..38966
                     /locus_tag="Calni_2106"
                     /note="InterPro IPR018631: IPR012547;
                     KEGG: ddf:DEFDS_0353 hypothetical protein;
                     PFAM: AAA-ATPase-like; protein of unknown function
                     DUF1703;
                     SPTR: Putative uncharacterized protein;
                     PFAM: Protein of unknown function (DUF1703); Predicted
                     AAA-ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA-ATPase"
                     /protein_id="YP_004046732.1"
                     /db_xref="GI:313652054"
                     /db_xref="GeneID:10004307"
                     /translation="MKKLPIGIQTFSKIREEGYIYIDKTEEAFELVNNFTYVFLSRPR
                     RFGKSLFLDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLTTLERVEDRA
                     IDIFKTNQRLLGIECENNKNPSSCFNELIQKAYEKYNQKVVILIDEYDKPILDVIENV
                     EQAKINRGFLRNLYSIIKDNDAYIRFAFLTGVSKFSKASIFSGLNMLTDISLNPKYGN
                     ICGYTQRDIETSFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPFDILQFISNGLVFDNY
                     WFETGTPSFLIKLLKERRYFLPNFSNIVVDKKLLSSFDVENIDLEVILFQSGYLTIEK
                     VIQTPRSIGYKLKIPNLEVQISLNDYILRYLFNYRESNDIQNQSYDAFYNGDLDVIRD
                     NLTTLFSSIPYTNYTKNELKLYEGFYASVVYSYLASLGFDLIGEDVTNKGRIDLTVFV
                     SDKVYIIEFKVDGVKGEALFQIKHKNYAQKYLDRGKDIYLVGIEFSSSERNIVNFEWE
                     KLER"
     misc_feature    37440..38234
                     /locus_tag="Calni_2106"
                     /note="Predicted AAA-ATPase; Region: AAA-ATPase_like;
                     pfam09820"
                     /db_xref="CDD:192394"
     misc_feature    38664..38936
                     /locus_tag="Calni_2106"
                     /note="Protein of unknown function (DUF1703); Region:
                     DUF1703; pfam08011"
                     /db_xref="CDD:149218"
     gene            39095..40642
                     /locus_tag="Calni_2107"
                     /db_xref="GeneID:10004308"
     CDS             39095..40642
                     /locus_tag="Calni_2107"
                     /note="InterPro IPR018631: IPR012547;
                     KEGG: saf:SULAZ_0529 conserved protein, with A weak
                     D-galactarate dehydratase/altronate hydrolase domain;
                     PFAM: AAA-ATPase-like; protein of unknown function
                     DUF1703;
                     SPTR: Conserved protein, with A weak D-galactarate
                     dehydratase/altronate hydrolase domain;
                     PFAM: Protein of unknown function (DUF1703); Predicted
                     AAA-ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA-ATPase"
                     /protein_id="YP_004046733.1"
                     /db_xref="GI:313652055"
                     /db_xref="GeneID:10004308"
                     /translation="MKKLPIGISTLQSIREDNCYYVDKTPFVKKLVDNGKYYFLSRPR
                     RFGKSLLVDTIKQAFLGNRELFKGLYLENNWDWEKKYPVIHIDFGGGVVQDAQDLKEW
                     IIKQLKRHMITYNVSVEEQNNARFIFTDLIISLKEIYKNPVVVLVDEYDKPILDNIDD
                     TEKAIEIREVLKDFYSVLKASDQYLKLVFLTGVSRFSKVSIFSGLNQLQDITLSPAFA
                     TICGYTQSELETVFSDRLEGVELEKLRYWYNGYSWLGDKVYNPFDVLLFLSEKIFRPY
                     WFETGTPTFLMEIILNNKVFLPKLEEIKASDEILANLDVDFLKIENLLFQSGYLTIKE
                     TKKLGLKTIYILTYPNFEVKMSFNNFFLSDILPVASDKEEVQNSIVEAIEENSLENLK
                     TALYSFFASIPNDWYRKNDLDSYEGFYASVVYALFTGSGLNTRSEDTTNLGKIDLTVL
                     YQDRAYIIEFKVVEKDSEGKALGQIKEKRYYEKYTDSCREINLIGIEFSKEKRNVVYF
                     EYETLER"
     misc_feature    39107..39904
                     /locus_tag="Calni_2107"
                     /note="Predicted AAA-ATPase; Region: AAA-ATPase_like;
                     pfam09820"
                     /db_xref="CDD:192394"
     misc_feature    40337..40618
                     /locus_tag="Calni_2107"
                     /note="Protein of unknown function (DUF1703); Region:
                     DUF1703; pfam08011"
                     /db_xref="CDD:149218"
     gene            complement(40869..41609)
                     /locus_tag="Calni_2108"
                     /db_xref="GeneID:10004309"
     CDS             complement(40869..41609)
                     /locus_tag="Calni_2108"
                     /note="InterPro IPR000412: IPR013526: IPR013525;
                     KEGG: ddf:DEFDS_2063 ABC transporter permease;
                     PFAM: ABC-2 type transporter;
                     SPTR: ABC transporter, permease;
                     PFAM: ABC-2 type transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 type transporter"
                     /protein_id="YP_004046734.1"
                     /db_xref="GI:313652056"
                     /db_xref="GeneID:10004309"
                     /translation="MINGFYGVYLRELLVLKSRLWKVILSSAISPLLFLLAFGYGVGR
                     NSEINGFSYLSFLLPGLITMSSMNQAYGISTEINISRFYFKVFDEFLLAPIPKWQIIL
                     GEVFYGITKGLMPGFIVIFYSFIIGVKLSINFYFFISLMMHLITFSLLGFIIALVVKN
                     HGDQFSFNTFFITPMIFLSGTFYPVDKMPSIIKYIAHIFPLTYSTHLIRSSLLLKTIS
                     TTDFCILLIMIIILSFIANKIVNKIETT"
     misc_feature    complement(41001..41555)
                     /locus_tag="Calni_2108"
                     /note="ABC-2 type transporter; Region: ABC2_membrane;
                     cl11417"
                     /db_xref="CDD:196223"
     gene            complement(41606..42457)
                     /locus_tag="Calni_2109"
                     /db_xref="GeneID:10004310"
     CDS             complement(41606..42457)
                     /locus_tag="Calni_2109"
                     /note="COGs: COG1131 ABC-type multidrug transport system
                     ATPase component;
                     InterPro IPR003593: IPR003439: IPR017871;
                     KEGG: ddf:DEFDS_2062 ABC transporter ATP-binding protein;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     SPTR: ABC transporter, ATP-binding protein;
                     PFAM: ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter related protein"
                     /protein_id="YP_004046735.1"
                     /db_xref="GI:313652057"
                     /db_xref="GeneID:10004310"
                     /translation="MQIKIINLMKKYGNSVALKNITFRIEDKTITALLGPNGAGKTTT
                     INILAGLLKPDDGEIYYGDLDFLTNSNKIKSIIGLVPQYNNIDKDLTLYQNLLIHSIL
                     FGVKKNEIKNRIEEILNFTGLTNHKNKEAGKLSGGMKRRLVIGRAILHRPKILFLDEP
                     TVGLDPATRRHIWDFVKNINKNFGCTVVLTTHYIEEAELLSDYVYFIDKGEIIKHGKP
                     ENLKNEMGKYALEIFIEGKTREEYFESKTEAIERLKQLTYVDMAKIREVNLEDVYLKL
                     TGKKIDI"
     misc_feature    complement(41792..42451)
                     /locus_tag="Calni_2109"
                     /note="P-loop containing Nucleoside Triphosphate
                     Hydrolases; Region: P-loop NTPase; cl09099"
                     /db_xref="CDD:158411"
     misc_feature    complement(41624..42430)
                     /locus_tag="Calni_2109"
                     /note="daunorubicin resistance ABC transporter ATP-binding
                     subunit; Region: drrA; TIGR01188"
                     /db_xref="CDD:130256"
     misc_feature    complement(42332..42355)
                     /locus_tag="Calni_2109"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(order(41882..41884,41981..41986,42212..42214,
                     42329..42337,42341..42346))
                     /locus_tag="Calni_2109"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(42212..42223)
                     /locus_tag="Calni_2109"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(42029..42058)
                     /locus_tag="Calni_2109"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(41981..41998)
                     /locus_tag="Calni_2109"
                     /note="Walker B; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(41963..41974)
                     /locus_tag="Calni_2109"
                     /note="D-loop; other site"
                     /db_xref="CDD:72971"
     misc_feature    complement(41876..41896)
                     /locus_tag="Calni_2109"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:72971"
     gene            42786..44120
                     /locus_tag="Calni_2110"
                     /db_xref="GeneID:10004311"
     CDS             42786..44120
                     /locus_tag="Calni_2110"
                     /note="COGs: COG1797 Cobyrinic acid a c-diamide synthase;
                     InterPro IPR004484: IPR017929: IPR011698;
                     KEGG: ddf:DEFDS_2061 cobyrinic acid a,c-diamide synthase;
                     PFAM: CobB/CobQ domain protein glutamine amidotransferase;
                     SPTR: Cobyrinic acid a,c-diamide synthase;
                     TIGRFAM: cobyrinic acid a,c-diamide synthase;
                     PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain;
                     CobB/CobQ-like glutamine amidotransferase domain;
                     TIGRFAM: cobyrinic acid a,c-diamide synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinic acid a,c-diamide synthase"
                     /protein_id="YP_004046736.1"
                     /db_xref="GI:313652058"
                     /db_xref="GeneID:10004311"
                     /translation="MVKKAVLIASDKSGSGKSLFTIFLSKYFTLKQKSVLPFKCGPDY
                     IDTLHLKNATGNNAYNLDTVLINKKKLRYNFLSKLNSYDMAVIEGVMGFYDGINYKTF
                     AGSTYEVAKMLNIPVLFILDTSSTSFTIAARIKGLVSLGEDINVAGVVLNNVGSEKHE
                     KMLINAIEYHTDLKVFGAIPKLKDFVLPSRHLGIYTAFEVKDNFYDDIVNTFSNYVDA
                     GKIYDNTDYIIDEITKDKKSITKDKKAYIAFDEAFNFYYHDNIDYLEENGFQVINFSP
                     LKGELPEKPDFIYFGGGYPELYAEQLSKNNNLKNYIKETSKKGLPIFAECGGMMFLSN
                     GIKVKNKFFEMCGVFDVNVEMTEKRQALGYVNVTSLKSTGFFEKDEEFIGHEFHYSKI
                     KECNENYVFKIKKVTDNSINYDGFVNNNTIASYTHFHFLSDNCIIKNIIKGV"
     misc_feature    42786..44111
                     /locus_tag="Calni_2110"
                     /note="cobyrinic acid a,c-diamide synthase; Validated;
                     Region: PRK01077"
                     /db_xref="CDD:179218"
     misc_feature    42795..43337
                     /locus_tag="Calni_2110"
                     /note="Ras-like GTPase superfamily. The Ras-like
                     superfamily of small GTPases consists of several families
                     with an extremely high degree of structural and functional
                     similarity. The Ras superfamily is divided into at least
                     four families in eukaryotes: the Ras...; Region:
                     Ras_like_GTPase; cl10444"
                     /db_xref="CDD:195960"
     misc_feature    43524..44108
                     /locus_tag="Calni_2110"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Cobyrinic Acid a,c-Diamide Synthase; Region:
                     GATase1_CobB; cd03130"
                     /db_xref="CDD:153224"
     misc_feature    order(43761..43763,44070..44072,44076..44078)
                     /locus_tag="Calni_2110"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153224"
     gene            44122..45111
                     /locus_tag="Calni_2111"
                     /db_xref="GeneID:10004312"
     CDS             44122..45111
                     /locus_tag="Calni_2111"
                     /EC_number="4.99.1.3"
                     /note="COGs: COG4822 Cobalamin biosynthesis protein CbiK
                     Co2+ chelatase;
                     InterPro IPR010388: IPR019758;
                     KEGG: ddf:DEFDS_2060 sirohydrochlorin cobaltochelatase;
                     PFAM: anaerobic cobalt chelatase;
                     PRIAM: Sirohydrochlorin cobaltochelatase;
                     SPTR: Sirohydrochlorin cobaltochelatase;
                     PFAM: Cobalt chelatase (CbiK)"
                     /codon_start=1
                     /transl_table=11
                     /product="Sirohydrochlorin cobaltochelatase"
                     /protein_id="YP_004046737.1"
                     /db_xref="GI:313652059"
                     /db_xref="GeneID:10004312"
                     /translation="MKKIIIFIFAALFLSKGVSMAQMEKKETEKNKTEKNAIVIASFG
                     TTYPSGLKSIINIINMVKNEFPDTEVRVTFTSNIIREIWQKRNKHPEEWIKKGVPKEI
                     LNVKGIVATLGELSDEGYKNIVIQSTHIYHGEEFSDLLEYARALNSIQTIKKRWKPFH
                     KITVSRPALGTYGDKINYHEDIKKAVKALKNDVELARKHNAALVYMGHGNEFYSTGIY
                     SETEKEFNIQYPDVKTFIGVVEGYPGLDDLMEKLKEQKVKKVILKPFMVVAGDHAIND
                     MAGDEPDSWKNVLNKEGIEVIPVIEGLGSNDDFARIFLEHLKDAINDGEIILK"
     misc_feature    44230..45087
                     /locus_tag="Calni_2111"
                     /note="Cobalt chelatase (CbiK); Region: CbiK; pfam06180"
                     /db_xref="CDD:148029"
     misc_feature    44230..44700
                     /locus_tag="Calni_2111"
                     /note="Class II Chelatase: a family of ATP-independent
                     monomeric or homodimeric enzymes that catalyze the
                     insertion of metal into protoporphyrin rings. This family
                     includes protoporphyrin IX ferrochelatase (HemH),
                     sirohydrochlorin ferrochelatase (SirB) and...; Region:
                     Chelatase_Class_II; cl02784"
                     /db_xref="CDD:186534"
     misc_feature    order(44248..44250,44524..44526)
                     /locus_tag="Calni_2111"
                     /note="active site"
                     /db_xref="CDD:48637"
     misc_feature    44722..45033
                     /locus_tag="Calni_2111"
                     /note="Anaerobic cobalamin biosynthetic cobalt chelatase
                     (CbiK), C-terminal domain. CbiK is part of the
                     cobalt-early path for cobalamin biosynthesis. It catalyzes
                     the insertion of cobalt into the oxidized form of
                     precorrin-2, factor II (sirohydrochlorin), the...; Region:
                     CbiK_C; cd03413"
                     /db_xref="CDD:48640"
     misc_feature    order(44743..44745,44755..44757,44935..44937)
                     /locus_tag="Calni_2111"
                     /note="active site"
                     /db_xref="CDD:48640"
     misc_feature    order(44758..44760,44770..44772,44782..44784,44914..44922,
                     44926..44928,44932..44934,45025..45027,45031..45033)
                     /locus_tag="Calni_2111"
                     /note="N-terminal domain interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:48640"
     gene            45108..46049
                     /locus_tag="Calni_2112"
                     /db_xref="GeneID:10004313"
     CDS             45108..46049
                     /locus_tag="Calni_2112"
                     /note="COGs: COG0609 ABC-type Fe3+-siderophore transport
                     system permease component;
                     InterPro IPR000522;
                     KEGG: ddf:DEFDS_2059 iron ABC transporter permease;
                     PFAM: transport system permease protein;
                     SPTR: Iron ABC transporter, permease;
                     PFAM: FecCD transport family"
                     /codon_start=1
                     /transl_table=11
                     /product="transport system permease protein"
                     /protein_id="YP_004046738.1"
                     /db_xref="GI:313652060"
                     /db_xref="GeneID:10004313"
                     /translation="MSRLILALIVTILIFSFSLTNGAVSLDSLTMKLLLNVRLPRVLT
                     AFIIGGMLSLGGSILQLILRNPLADGFTTGISASAALGAVINIVLGLNILFTPIIAIL
                     FAIIGIYIIFKLTSIDKSFHYTTIILAGIILNIICSAIISFLKYYFDESLGSIIYWLM
                     GGFYDLSYSKVFVLFLVLLSSLFILLKNSFKLNILAYDYKTASSLGVDVATIRKKLFI
                     IVSLLIAFAVSFSGIIGFVGLIIPHMVRGLFKPDMKIHLIYSTLFGANFLLLSDTICR
                     MIIPSGAELPVGVATSFFGGIFFLFLMKYRLKNIWYG"
     misc_feature    45177..>45377
                     /locus_tag="Calni_2112"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist...; Region:
                     TM_ABC_iron-siderophores_like; cl00462"
                     /db_xref="CDD:193828"
     misc_feature    <45531..46016
                     /locus_tag="Calni_2112"
                     /note="Transmembrane subunit (TM), of Periplasmic Binding
                     Protein (PBP)-dependent ATP-Binding Cassette (ABC)
                     transporters involved in the uptake of siderophores, heme,
                     vitamin B12, or the divalent cations Mg2+ and Zn2+.
                     PBP-dependent ABC transporters consist...; Region:
                     TM_ABC_iron-siderophores_like; cd06550"
                     /db_xref="CDD:119348"
     misc_feature    order(45531..45536,45540..45542,45573..45578,45585..45587,
                     45813..45815,45972..45974,45981..45986,45993..45995,
                     46002..46007,46014..46016)
                     /locus_tag="Calni_2112"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(45540..45542,45615..45617,45789..45791,45801..45803,
                     45933..45935,45963..45965)
                     /locus_tag="Calni_2112"
                     /note="putative PBP binding regions; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(45663..45668,45672..45680,45684..45689,45693..45710,
                     45714..45722,45843..45845,45864..45866)
                     /locus_tag="Calni_2112"
                     /note="ABC-ATPase subunit  interface; other site"
                     /db_xref="CDD:119348"
     gene            46042..46782
                     /locus_tag="Calni_2113"
                     /db_xref="GeneID:10004314"
     CDS             46042..46782
                     /locus_tag="Calni_2113"
                     /note="COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores
                     transport systems ATPase components;
                     InterPro IPR003593: IPR003439: IPR017871;
                     KEGG: ddf:DEFDS_2058 iron ABC transporter ATP-binding
                     protein;
                     PFAM: ABC transporter related;
                     SMART: AAA ATPase;
                     SPTR: Iron ABC transporter, ATP-binding protein;
                     PFAM: ABC transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter related protein"
                     /protein_id="YP_004046739.1"
                     /db_xref="GI:313652061"
                     /db_xref="GeneID:10004314"
                     /translation="MDKMNTIDIKNLNARVGDFTLKIDSLTVSKGEKIALLGENGAGK
                     STLLDIISGVNKNFTGELNILNKQISNYKPIELANLISYLPQFSEIIFGFDVFDTVLF
                     GRYPKTSGKFEDYDFENTKEWLKKLDIYHLKDRKFNELSGGEKKRVMLARVLNQDTDI
                     ILLDEPFSMLDVKHTKIAKEILVNEKKSIILSSHDINILKYLVDEIVFLKKGEVLCKV
                     NIDNLNKEILNEVFEVDFKCIDGFYFVN"
     misc_feature    46060..46761
                     /locus_tag="Calni_2113"
                     /note="ABC-type cobalamin/Fe3+-siderophores transport
                     systems, ATPase components [Inorganic ion transport and
                     metabolism / Coenzyme metabolism]; Region: FepC; COG1120"
                     /db_xref="CDD:31317"
     misc_feature    46063..46689
                     /locus_tag="Calni_2113"
                     /note="ABC transporters, involved in the uptake of
                     siderophores, heme, and vitamin B12, are widely conserved
                     in bacteria and archaea.  Only very few species lack
                     representatives of the siderophore family transporters.
                     The E. coli BtuCD protein is an ABC...; Region:
                     ABC_Iron-Siderophores_B12_Hemin; cd03214"
                     /db_xref="CDD:72973"
     misc_feature    46153..46176
                     /locus_tag="Calni_2113"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:72973"
     misc_feature    order(46162..46167,46171..46179,46297..46299,46531..46536,
                     46621..46623)
                     /locus_tag="Calni_2113"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:72973"
     misc_feature    46288..46299
                     /locus_tag="Calni_2113"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:72973"
     misc_feature    46459..46488
                     /locus_tag="Calni_2113"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:72973"
     misc_feature    46519..46536
                     /locus_tag="Calni_2113"
                     /note="Walker B; other site"
                     /db_xref="CDD:72973"
     misc_feature    46543..46554
                     /locus_tag="Calni_2113"
                     /note="D-loop; other site"
                     /db_xref="CDD:72973"
     misc_feature    46609..46629
                     /locus_tag="Calni_2113"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:72973"
     gene            46727..47521
                     /locus_tag="Calni_2114"
                     /db_xref="GeneID:10004315"
     CDS             46727..47521
                     /locus_tag="Calni_2114"
                     /note="COGs: COG0614 ABC-type Fe3+-hydroxamate transport
                     system periplasmic component;
                     InterPro IPR002491;
                     KEGG: ddf:DEFDS_2057 iron ABC transporter
                     substrate-binding protein;
                     PFAM: periplasmic binding protein;
                     SPTR: Iron ABC transporter, substrate-binding protein;
                     PFAM: Periplasmic binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic binding protein"
                     /protein_id="YP_004046740.1"
                     /db_xref="GI:313652062"
                     /db_xref="GeneID:10004315"
                     /translation="MKFLKWILNVLMGFILLTNSCIAYERVILLSPACADIFAELGLK
                     NKVVGITKHVKGFDNAIEVGSHLKPNLELMLSLNPDLIIYSNDHFLPDRFDKFNIKTY
                     RYDPKTVDEIFEQIKEIASMMNVSESGNSLIFKLKSKLSQLKKLNKKPKVIYEVTQTP
                     YIVAGKNSIINDIIKQAGGINAIDINKKLVKFSIEKAVSLNPDIYIYQIGPMNEAPTS
                     PEERPIFKNMGTIFIKVNELDFARANTKTIDNILFLNNIFYKWSLK"
     misc_feature    46799..47419
                     /locus_tag="Calni_2114"
                     /note="Helical backbone metal receptor (TroA-like domain).
                     These proteins have been shown to function in the ABC
                     transport of ferric siderophores and metal ions such as
                     Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site
                     is formed in the interface...; Region: TroA-like; cl00262"
                     /db_xref="CDD:193735"
     misc_feature    46805..47410
                     /locus_tag="Calni_2114"
                     /note="Periplasmic binding protein; Region: Peripla_BP_2;
                     pfam01497"
                     /db_xref="CDD:144914"
     misc_feature    order(47009..47014,47087..47089)
                     /locus_tag="Calni_2114"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29734"
     gene            47518..48279
                     /locus_tag="Calni_2115"
                     /db_xref="GeneID:10004316"
     CDS             47518..48279
                     /locus_tag="Calni_2115"
                     /note="COGs: COG0007 Uroporphyrinogen-III methylase;
                     InterPro IPR006366: IPR003043: IPR000878;
                     KEGG: ddf:DEFDS_2056 uroporphyrin-III C-methyltransferase;
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     SPTR: Uroporphyrin-III C-methyltransferase;
                     TIGRFAM: uroporphyrin-III C-methyltransferase;
                     PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases;
                     TIGRFAM: uroporphyrin-III C-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrin-III C-methyltransferase"
                     /protein_id="YP_004046741.1"
                     /db_xref="GI:313652063"
                     /db_xref="GeneID:10004316"
                     /translation="MRKLILIGAGLNKDLMTLKGLNKLKEADIILYDRLVDNSLLEAV
                     NCEKIFVGKTPYRPGCSQCEINSLIERALLENKTVVRIKGGDSSIYSRSLEEIEVARK
                     CNALIEIVPGVTAASQFVAKLETALTARGISSGVIFITGHKKDVELNEAYNWKAIVDL
                     KMTIVVYMGIKNFMKILKLLVENGLHEKTPIAIGEKLDFEDENIIVSDVENLLNSNFD
                     IRFPAILLIGEVVKFSKFFKNSITIKNERCIKCAN"
     misc_feature    47518..48219
                     /locus_tag="Calni_2115"
                     /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region:
                     TP_methylase; cl00304"
                     /db_xref="CDD:197405"
     gene            48267..48974
                     /locus_tag="Calni_2116"
                     /db_xref="GeneID:10004317"
     CDS             48267..48974
                     /locus_tag="Calni_2116"
                     /note="COGs: COG2243 Precorrin-2 methylase;
                     InterPro IPR006364: IPR012382: IPR000878;
                     KEGG: ddf:DEFDS_2055 precorrin-2 C(20)-methyltransferase;
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     SPTR: Precorrin-2 C(20)-methyltransferase;
                     TIGRFAM: precorrin-2 C20-methyltransferase;
                     PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases;
                     TIGRFAM: precorrin-2 C20-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 C20-methyltransferase"
                     /protein_id="YP_004046742.1"
                     /db_xref="GI:313652064"
                     /db_xref="GeneID:10004317"
                     /translation="MRKLIHAIGLGPGDPESINLKALATLKNSDVVVTPESDKNGRSL
                     AKEIVSKHISSSKIFTYYFPMNNDKNLLDKRYKELAEIIDNFLSEGKKVSYVTIGDLS
                     IYSTFNYLEKKLKLFDIDVIKIPGIPSFIAAANRINESLVVKDEPFCVVELSNNLDKL
                     DDLLSNFPTVVIMKVYKRLNELVAFVRNSNLVKKGFLIERATLPEERVFDLLTDDIPE
                     EAGYLSTAILFSRVKDE"
     misc_feature    48267..48950
                     /locus_tag="Calni_2116"
                     /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region:
                     TP_methylase; cl00304"
                     /db_xref="CDD:197405"
     gene            48967..49584
                     /locus_tag="Calni_2117"
                     /db_xref="GeneID:10004318"
     CDS             48967..49584
                     /locus_tag="Calni_2117"
                     /EC_number="5.4.1.2"
                     /note="COGs: COG2082 Precorrin isomerase;
                     InterPro IPR003722;
                     KEGG: ddf:DEFDS_2054 precorrin-8X methylmutase;
                     PFAM: Precorrin-8X methylmutase CbiC/CobH;
                     PRIAM: Precorrin-8X methylmutase;
                     SPTR: Precorrin-8X methylmutase;
                     PFAM: Precorrin-8X methylmutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Precorrin-8X methylmutase"
                     /protein_id="YP_004046743.1"
                     /db_xref="GI:313652065"
                     /db_xref="GeneID:10004318"
                     /translation="MNKGLSIEKESFDIIEQNVDLSKYSDEEKVVVKRVIHASGDFDF
                     AKTIIFSHNWLTDSKKIIQKKPAVVCDVNMVKAGITEKYLKVSGLTTHCFISDEKIHE
                     LAILEGKTRAETSIEYAFKNFDNIIFVIGNAPTALLKVLELNSLYTDKNIFVVGFPVG
                     FVKAEESKEILTKTDIPFITNKGTKGGSGIAAAAFNALIKVCFNV"
     misc_feature    48967..49563
                     /locus_tag="Calni_2117"
                     /note="Precorrin isomerase [Coenzyme metabolism]; Region:
                     CobH; cl00913"
                     /db_xref="CDD:197416"
     misc_feature    48985..49566
                     /locus_tag="Calni_2117"
                     /note="Precorrin-8X methylmutase; Region: CbiC; pfam02570"
                     /db_xref="CDD:145615"
     gene            49577..50272
                     /locus_tag="Calni_2118"
                     /db_xref="GeneID:10004319"
     CDS             49577..50272
                     /locus_tag="Calni_2118"
                     /note="COGs: COG2099 Precorrin-6x reductase;
                     InterPro IPR003723;
                     KEGG: ddf:DEFDS_2053 precorrin-6A reductase;
                     PFAM: Precorrin-6x reductase CbiJ/CobK;
                     SPTR: Precorrin-6A reductase;
                     TIGRFAM: precorrin-6x reductase;
                     PFAM: Precorrin-6x reductase CbiJ/CobK;
                     TIGRFAM: precorrin-6x reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6x reductase"
                     /protein_id="YP_004046744.1"
                     /db_xref="GI:313652066"
                     /db_xref="GeneID:10004319"
                     /translation="MCKKILILGGTSDTEKYLNICSKNEFIISVATEYGYKIFSKKFG
                     KDRVILKRFDEKSLEDFIKENSIYKIIDTTHPFAKEITKIAKDAANNLNIIYESMIRE
                     NEINITYEKLIYVNSLKEAITFLRENDFKKILLTIGSKMIKHFSFLNEKAHVRILPFE
                     QSIKDVLEAGFDYDKIIAIQGPFSKDFNKAIIKEFEIELLVTKVSGQSGGYEEKVEAC
                     REMGIFCLAIKNW"
     misc_feature    49577..50263
                     /locus_tag="Calni_2118"
                     /note="Precorrin-6x reductase CbiJ/CobK; Region: CbiJ;
                     cl00922"
                     /db_xref="CDD:186262"
     gene            50471..51532
                     /locus_tag="Calni_2119"
                     /db_xref="GeneID:10004320"
     CDS             50471..51532
                     /locus_tag="Calni_2119"
                     /note="COGs: COG0079 Histidinol-phosphate/aromatic
                     aminotransferase and cobyric acid decarboxylase;
                     InterPro IPR004838: IPR004839;
                     KEGG: ddf:DEFDS_2048 L-threonine-O-3-phosphate
                     decarboxylase;
                     PFAM: aminotransferase class I and II;
                     SPTR: L-threonine-O-3-phosphate decarboxylase;
                     PFAM: Aminotransferase class I and II;
                     TIGRFAM: histidinol-phosphate aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I and II"
                     /protein_id="YP_004046745.1"
                     /db_xref="GI:313652067"
                     /db_xref="GeneID:10004320"
                     /translation="MDNFSHGGNIYYYANLIGCNPNEIIDLSSNISPFVDENIFEFIK
                     NQLSNLKNLPSSNAFILKEALAKKYDKDMENFVVGVGTSEIIKNLCLINSGNKALIIA
                     PTYIDYEKYCKLYNLHTSFHFTSERRNFAINLQELDFSKFDITFICNPNNPTGYYIQK
                     EEILKAAKLFENCLFVIDESYLPFMIDSDNASLLFEKTKNIIVLRSFSKIYGLAGLRI
                     GYAFSFNKDNIREIEKHCLEWGVSSLSEVVGKYLLSLETDQIASKINEIKGYLYEELK
                     CCNNIKPLPSSTNFLLIKLTHLNSEKVFNNLLSNKILIRDCKNIRGLDDLFIRVAIKD
                     LDSMKYFLSVFKKLVGCKN"
     misc_feature    50531..51520
                     /locus_tag="Calni_2119"
                     /note="Histidinol-phosphate/aromatic aminotransferase and
                     cobyric acid decarboxylase [Amino acid transport and
                     metabolism]; Region: HisC; COG0079"
                     /db_xref="CDD:30428"
     misc_feature    50543..51511
                     /locus_tag="Calni_2119"
                     /note="Aspartate aminotransferase family. This family
                     belongs to pyridoxal phosphate (PLP)-dependent aspartate
                     aminotransferase superfamily (fold I). Pyridoxal phosphate
                     combines with an alpha-amino acid to form a compound
                     called a Schiff base or aldimine...; Region: AAT_like;
                     cd00609"
                     /db_xref="CDD:99734"
     misc_feature    order(50711..50719,50783..50785,50924..50926,51011..51013,
                     51086..51088,51092..51097,51119..51121)
                     /locus_tag="Calni_2119"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99734"
     misc_feature    order(50720..50722,50813..50815,50990..50992,51113..51121,
                     51203..51205,51212..51214)
                     /locus_tag="Calni_2119"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99734"
     misc_feature    51095..51097
                     /locus_tag="Calni_2119"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
     gene            51528..52967
                     /locus_tag="Calni_2120"
                     /db_xref="GeneID:10004321"
     CDS             51528..52967
                     /locus_tag="Calni_2120"
                     /note="COGs: COG1492 Cobyric acid synthase;
                     InterPro IPR004459: IPR017929: IPR011698;
                     KEGG: ddf:DEFDS_2047 adenosylcobyric acid synthase
                     (glutamine-hydrolyzing);
                     PFAM: CobB/CobQ domain protein glutamine amidotransferase;
                     SPTR: Cobyric acid synthase;
                     TIGRFAM: cobyric acid synthase CobQ;
                     manually curated;
                     PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain;
                     CobB/CobQ-like glutamine amidotransferase domain;
                     TIGRFAM: cobyric acid synthase CobQ"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase CobQ"
                     /protein_id="YP_004046746.1"
                     /db_xref="GI:313652068"
                     /db_xref="GeneID:10004321"
                     /translation="MKNIMVQGTSSNVGKSIITAGICRMLANKGYKVAPFKAQNMALN
                     SGVTFDGLEMGRAQILQAEACKILPDVRMNPILLKPTGDGKSQIIRLGKPYKTVSYKD
                     YYQIYEENLKIVKEAFYSLSKEFDIIVLEGAGSPAEINLQKFDIVNMKMAEIARAKVY
                     IVGDIDRGGVFAAFKGTYDLIQPHYKKFVKGFIINKFRGDLSLLKPGIDGFKDFCDIP
                     IIGVIPYFEHNLEDEDSQNLFTKKNKKSGEILLNIGIIRLPYMSNFTDFQCLENIEKI
                     NVEYFTKPENSESYDLIIIPGSKNTISDMDYLLKTGFYEQIKKLYGKKWIMGICGGFQ
                     MLGKKIIDSLNVENKGEIEGFGFIDMITEMKEEKVLKIGEYLPANDFLNKSICGYEIH
                     HGNTIINDRDVIDMLENESLLVFNKEKRIIGTYLHGIFENSNFLQFIFNLFNKQIEIN
                     KTYKVIKEETLDKLANLIEKNLLGDIIND"
     misc_feature    51528..52943
                     /locus_tag="Calni_2120"
                     /note="cobyric acid synthase; Provisional; Region:
                     PRK00784"
                     /db_xref="CDD:179125"
     misc_feature    51537..>51653
                     /locus_tag="Calni_2120"
                     /note="Ras-like GTPase superfamily. The Ras-like
                     superfamily of small GTPases consists of several families
                     with an extremely high degree of structural and functional
                     similarity. The Ras superfamily is divided into at least
                     four families in eukaryotes: the Ras...; Region:
                     Ras_like_GTPase; cl10444"
                     /db_xref="CDD:195960"
     misc_feature    <51870..52199
                     /locus_tag="Calni_2120"
                     /note="Ras-like GTPase superfamily. The Ras-like
                     superfamily of small GTPases consists of several families
                     with an extremely high degree of structural and functional
                     similarity. The Ras superfamily is divided into at least
                     four families in eukaryotes: the Ras...; Region:
                     Ras_like_GTPase; cl10444"
                     /db_xref="CDD:195960"
     misc_feature    52284..52847
                     /locus_tag="Calni_2120"
                     /note="Type 1 glutamine amidotransferase (GATase1) domain
                     found in Cobyric Acid Synthase (CobQ); Region:
                     GATase1_CobQ; cd01750"
                     /db_xref="CDD:153221"
     misc_feature    order(52515..52517,52701..52703,52707..52709)
                     /locus_tag="Calni_2120"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153221"
     gene            52960..53907
                     /locus_tag="Calni_2121"
                     /db_xref="GeneID:10004322"
     CDS             52960..53907
                     /locus_tag="Calni_2121"
                     /note="COGs: COG1270 Cobalamin biosynthesis protein
                     CobD/CbiB;
                     InterPro IPR004485;
                     KEGG: ddf:DEFDS_2046 adenosylcobinamide-phosphate
                     synthase;
                     PFAM: cobalamin biosynthesis protein CbiB;
                     SPTR: Adenosylcobinamide-phosphate synthase;
                     TIGRFAM: cobalamin biosynthesis protein CobD;
                     PFAM: CobD/Cbib protein;
                     TIGRFAM: cobalamin biosynthesis protein CobD"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CobD"
                     /protein_id="YP_004046747.1"
                     /db_xref="GI:313652069"
                     /db_xref="GeneID:10004322"
                     /translation="MTNILVLAILIDIVFGELPNKIHPVAIIGKLISVYENIFYNLKN
                     KFLGGFLLFISTHITIITVIFFLLKILKSNYLLFPLKVFIVYSLISVRGMIDHAMKIY
                     QALSIDINLAKENLKLIVSRDVDAMNEQDIIKSSIESIAENFCDAFFAPIFYGVIFGI
                     YGIIFYRVTNTLDAMVGYKNEKYMEFGKFSARSDDILNFIPARLQLIILLPVSQILFK
                     NGLNSLEIYKKFRNTLSSPNSGCGISLFAGALNITLGGDTYYFGKLVNKPLITGGGDL
                     LTKQKLLDAIFLYLYSAIFTVLLIIIFQLLWSQNVPFNL"
     misc_feature    52969..53880
                     /locus_tag="Calni_2121"
                     /note="CobD/Cbib protein; Region: CobD_Cbib; cl00561"
                     /db_xref="CDD:193870"
     gene            53888..54343
                     /locus_tag="Calni_2122"
                     /db_xref="GeneID:10004323"
     CDS             53888..54343
                     /locus_tag="Calni_2122"
                     /note="COGs: COG1648 Siroheme synthase (precorrin-2
                     oxidase/ferrochelatase domain);
                     InterPro IPR006367;
                     KEGG: ddf:DEFDS_2045 hypothetical protein;
                     SPTR: Putative uncharacterized protein;
                     TIGRFAM: siroheme synthase;
                     TIGRFAM: siroheme synthase, N-terminal domain"
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase"
                     /protein_id="YP_004046748.1"
                     /db_xref="GI:313652070"
                     /db_xref="GeneID:10004323"
                     /translation="MFPLIFKLSDKKLLFIGGGNIAKRKLLSILNQSNPEVTIISKEL
                     HPDIKKLLSTNKITWIKSSFKEELLKQKYDLAFICTDDKELNTKAALILKKIGTPTNI
                     CDNKELSDFFTPAIVSQDDIIISISTKGKSPAFAKQLKEVISKTLKELK"
     misc_feature    53888..54337
                     /locus_tag="Calni_2122"
                     /note="precorrin-2 dehydrogenase; Validated; Region:
                     PRK06719"
                     /db_xref="CDD:180668"
     gene            54340..55314
                     /locus_tag="Calni_2123"
                     /db_xref="GeneID:10004324"
     CDS             54340..55314
                     /locus_tag="Calni_2123"
                     /note="COGs: COG1903 Cobalamin biosynthesis protein CbiD;
                     InterPro IPR002748;
                     KEGG: ddf:DEFDS_2044 cobalamin biosynthesis protein CbiD;
                     PFAM: cobalamin (vitamin B12) biosynthesis CbiD protein;
                     SPTR: Putative cobalt-precorrin-6A synthase
                     [deacetylating];
                     TIGRFAM: cobalamin biosynthesis protein CbiD;
                     PFAM: CbiD;
                     TIGRFAM: cobalamin biosynthesis protein CbiD"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiD"
                     /protein_id="YP_004046749.1"
                     /db_xref="GI:313652071"
                     /db_xref="GeneID:10004324"
                     /translation="MKTGITTGTAATAAAKGALIYKLTGKIEKEVEVILPYGCSIKIP
                     LIFKNNLVGVKKWSGDDPDVTDGIEIFASVRMLNENRIIIKGGEGVGIVTKPGLQIPV
                     GEAAINPVPKKMIEKNLKTLLDNNQGVEVTIIVPEGREIAKNTFNKRLGIIDGISIIG
                     TTGIVKPMSVDALIESFKCEIDVLIAQRYNFLWIVPGNIGEKCLLQENITPSVMVSNY
                     FKESFEYLKDRNINEIGVAGHPGKIAKLAMGYFNTHSKNSPQANRFVKEVLNINHDFN
                     TIEELCNSYSFDKIAYLVSKKIKEKFDFTKVSVKLFDMKCNKVGEYLE"
     misc_feature    54406..55311
                     /locus_tag="Calni_2123"
                     /note="CbiD; Region: CbiD; cl00828"
                     /db_xref="CDD:186211"
     gene            55307..55945
                     /locus_tag="Calni_2124"
                     /db_xref="GeneID:10004325"
     CDS             55307..55945
                     /locus_tag="Calni_2124"
                     /note="COGs: COG2241 Precorrin-6B methylase 1;
                     InterPro IPR012818: IPR000878;
                     KEGG: ddf:DEFDS_2043 precorrin-6Y
                     C(5,15)-methyltransferase (decarboxylating);
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     SPTR: Precorrin-6Y C(5,15)-methyltransferase
                     (Decarboxylating);
                     TIGRFAM: precorrin-6y C5,15-methyltransferase
                     (decarboxylating), CbiE subunit;
                     PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases;
                     TIGRFAM: precorrin-6y C5,15-methyltransferase
                     (decarboxylating), CbiE subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6y C5,15-methyltransferase
                     (decarboxylating), CbiE subunit"
                     /protein_id="YP_004046750.1"
                     /db_xref="GI:313652072"
                     /db_xref="GeneID:10004325"
                     /translation="MNKNIYIISAGCGSKDYLTLRAFETAKKVDFLIGAERFKDLFPD
                     KKYIILNNLIKDTINILENEKEKIVGVVVSGDAGFFSLAKIIYKKFKNRIIEVIPGIS
                     SMQLGMARMFKTYESIEFFSLHGRNIPIENFEKKIDKCLQQKKDLYVLDDKNKQFFEL
                     LSRSKEILSLFDIYILNNLGLPDETIYKLKTINDLNNIKLELYSIYLEVRNK"
     misc_feature    55319..55924
                     /locus_tag="Calni_2124"
                     /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region:
                     TP_methylase; cl00304"
                     /db_xref="CDD:197405"
     gene            55942..56637
                     /locus_tag="Calni_2125"
                     /db_xref="GeneID:10004326"
     CDS             55942..56637
                     /locus_tag="Calni_2125"
                     /EC_number="2.1.1.133"
                     /note="COGs: COG2875 Precorrin-4 methylase;
                     InterPro IPR006362: IPR003043: IPR000878;
                     KEGG: ddf:DEFDS_2042 precorrin-4 C(11)-methyltransferase;
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     PRIAM: Precorrin-4 C(11)-methyltransferase;
                     SPTR: Precorrin-4 C(11)-methyltransferase;
                     TIGRFAM: precorrin-4 C11-methyltransferase;
                     PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases;
                     TIGRFAM: precorrin-4 C11-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-4 C11-methyltransferase"
                     /protein_id="YP_004046751.1"
                     /db_xref="GI:313652073"
                     /db_xref="GeneID:10004326"
                     /translation="MNKVFFIGAGPGDPELITVKGMKILTKSDIIIYAGSLVNKQILE
                     YAPAGCKIYDSSKMNLTQIIEIIERHHLEGKVIARLHTGDPSIYGAIYEQMLELDKRG
                     IPYEIIPGVTALFAAAAKLKIELTAPEISQTLTISRVEGKTAVPQTESLDLLTKHGGT
                     FSFYLSASNAERIKETFLKNGWKENTPVAICYKICWDDEKILNTTLGGLVNTLKENNI
                     KKPYSYYNWQDFG"
     misc_feature    55951..56601
                     /locus_tag="Calni_2125"
                     /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region:
                     TP_methylase; cl00304"
                     /db_xref="CDD:197405"
     gene            56685..57470
                     /locus_tag="Calni_2126"
                     /db_xref="GeneID:10004327"
     CDS             56685..57470
                     /locus_tag="Calni_2126"
                     /note="COGs: COG2073 Cobalamin biosynthesis protein CbiG;
                     InterPro IPR002750;
                     KEGG: ddf:DEFDS_2041 cobalamin biosynthesis protein CbiG;
                     PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein;
                     SPTR: Cobalamin biosynthesis protein CbiG;
                     PFAM: Cobalamin synthesis G C-terminus; Cobalamin
                     synthesis G N-terminal"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin (vitamin B12) biosynthesis CbiG
                     protein"
                     /protein_id="YP_004046752.1"
                     /db_xref="GI:313652074"
                     /db_xref="GeneID:10004327"
                     /translation="MDTEKKIAVIAITEKGALLANKISDELNGILFLPEKFRGRIKAT
                     YFQELQEICKFCFDNFKGIIAVMAQGIVTRMINGLIKSKYTDPAVVVCDEVGRFSISM
                     LSGHEGGANELTFLVSSITGAEPVITTASEANKIYVVGIGCRKGVDKQTVVEAISYCS
                     KLANISINDIRVIVSCWHKKNETGLIEAAKELNCYLRFLPKEIYNNELYCFKESTAKK
                     YLGIKSVAEPSALLAARNPILVLNKTIFNGVTIAIAKENLING"
     misc_feature    56736..57449
                     /locus_tag="Calni_2126"
                     /note="Cobalamin biosynthesis protein CbiG [Coenzyme
                     metabolism]; Region: CbiG; COG2073"
                     /db_xref="CDD:32256"
     misc_feature    56853..57080
                     /locus_tag="Calni_2126"
                     /note="Cobalamin synthesis G N-terminal; Region: CbiG_N;
                     pfam11760"
                     /db_xref="CDD:152196"
     misc_feature    57093..57449
                     /locus_tag="Calni_2126"
                     /note="Cobalamin synthesis G C-terminus; Region: CbiG_C;
                     cl12133"
                     /db_xref="CDD:196350"
     gene            57463..58194
                     /locus_tag="Calni_2127"
                     /db_xref="GeneID:10004328"
     CDS             57463..58194
                     /locus_tag="Calni_2127"
                     /EC_number="2.1.1.131"
                     /note="COGs: COG1010 Precorrin-3B methylase;
                     InterPro IPR006363: IPR000878;
                     KEGG: ddf:DEFDS_2040 precorrin-3B C(17)-methyltransferase;
                     PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin)
                     methyltransferase;
                     PRIAM: Precorrin-3B C(17)-methyltransferase;
                     SPTR: Precorrin-3B C(17)-methyltransferase;
                     TIGRFAM: precorrin-3B C17-methyltransferase;
                     PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases;
                     TIGRFAM: precorrin-3B C17-methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3 methyltransferase"
                     /protein_id="YP_004046753.1"
                     /db_xref="GI:313652075"
                     /db_xref="GeneID:10004328"
                     /translation="MGKLFVVGIGPGKHDLITRRGLDAILSSDLICGYNKYIELLDSL
                     VCNKPIFSNGMKGEIERVKFAIDKAKSGKTVSLVCGGDSSLYALASLVFELCDDFENI
                     EIIPGITAALSASTKLGAPICEDLVILSLSDLLTPFEIIKKRVDAINIGDFVTAIYNP
                     KSQKRDKYLKEVLESFYQQRGDLICGIVKNCDRDDELVKITKITDFDYDIVDMSTVVI
                     VGNTKSYIKNDKMITPRGYLIKYNR"
     misc_feature    57472..58173
                     /locus_tag="Calni_2127"
                     /note="Tetrapyrrole (Corrin/Porphyrin) Methylases; Region:
                     TP_methylase; cl00304"
                     /db_xref="CDD:197405"
     gene            complement(58218..58366)
                     /locus_tag="Calni_2128"
                     /pseudo
                     /db_xref="GeneID:10004329"
ORIGIN      
        1 agtttttggg tgtaaaaaat ataatcagat ataatataga tttttattaa aacaccaatc
       61 taaaatttgt accccctata aggtcatgaa atgggtctat tttgcaagat agggggtagg
      121 tggctgttgg ggtatgccag accacaaaaa tgcgttaaaa caaaaaaata tggcttctgg
      181 tgtaacattg cattctggag gtttggatcc tggaagattt tatttttgat caattgaaat
      241 tttaacctaa aaaaatcacc cgtagtgaca aaatgtacaa ttttaaaatt gtaaagttaa
      301 tatctacaat gagttacgaa atcaaagtgt caaagatggg tccaaacaat atcttttctg
      361 ctctgacttt tggaggagcg gtcgtcgggc tttgtatttt gctttatagc gcgcttgttc
      421 gctctgtatc ttacgaggat tttgtcatct gggctgtata tgctatttag ctcatttttg
      481 cgttttttat cgctcgcaca aaaggcaaat actgcgtagt agagcatata tcaaacggct
      541 ctatatctgt tggactgctg atggcgttta tctctatcgc gataggtata ctaaacgctg
      601 ggtcgatgag ttactaagaa tcaaattcga tagagggttg atggcaaaag cttaagttag
      661 tctttttccg aatgcatttt aatctttagg cttatttgta ttgcggtatc caagccaaag
      721 cacgactagt cctattgcga taaaaaagcc accttcgata aagatgagtg gggcataagc
      781 tctggtagaa gcgtctgaag cgatgtcaat atatccggtg atggtatata tggtggcgac
      841 aagagtaata ccccatccgg catactttgt gacttttttg cctaatcctt catttgcgct
      901 ttgcattttt actctcctgg taaatgtttg gtctggtatc ttataagtcg caagctgtgg
      961 ccctcaccca tttttaggac attccaaaaa ttaagttttt ctgtatttga gattgtaaca
     1021 caaactgccc tcattagtca agacaacttt atctgctgcc atcaccccat tttttgcacc
     1081 cctgaaccaa agataaatgt ctcttccaaa aattatgcaa tttgaaatta aaatcattta
     1141 aatagattga tgtcagtaaa tatctcttat tctattaaca taaattttag agtttattac
     1201 atctacctta caagagttat ctttgtataa tccataagta tttttgtata gtgtggaatt
     1261 taaaattttt acctgtgatg atacacaata aacaccagtt ccatttacag aattaaacac
     1321 ctgactgtca tctaattcta cttcagagtt tcaaatccat atttgtggtt agctaccttc
     1381 attatttcca ttttcgtaga ttttagaatt tataattttt actttactgt tttcttcaga
     1441 ttttaatccg tggtaataat ttttatagac tttacagttt tgaatttcca attcagaaga
     1501 attgcatcta ataccactac taccagaatt gtgtatttca cactctatga tatgaccttg
     1561 cgagttttca aaataaactt ctccctctat tttacagctt aatatattta tttctctttt
     1621 acctattacc tttatgatag gattcagatg cattctttga tctttttatt tccaaatcta
     1681 tcaaactaac gttatcatca tctataatta tctctccacc tttaagaatt tttatctttc
     1741 ctcctttacc tattaaagtt tcttttagat acgacttttc ttttacctct atgtaaccat
     1801 caacctttat gctattttta gatttttttt aagcttaatc ttttctcttt gaagaagaga
     1861 ttatcaaatt cttttaaaac aatctcttct aaatttttta gatccgctaa gttcttttta
     1921 ttttctgcaa ttttgctttg aaatttagtt tttaagctat ctaatctgtc ataaaaagat
     1981 gtagactttg caagtttttc atcttttcca acctgaaaaa tgtcaagttc cattgatttg
     2041 aacgatgata aaaagctttc agcttctttt atgtcgctct ttaaaaatgt ctcataatct
     2101 ctgaaaatag attttagctc ttctcttaaa ctatctttca aatcagaagg cctgtcttcc
     2161 tcttttaaaa attgaaataa acttttaccg tgataccata attcttggtt atttatagat
     2221 gaaaaggcac ttatcccttc cacttttata ccatttttct caagctcatt tttaactgcc
     2281 tcgccaattt tttctatatc tggtaaactc cttgtatctg ccttgtttaa ggctatgtat
     2341 attttcttat tgcttgaatt aataccacgt aaaaagtcta tatctgattt tggaattgtt
     2401 ccgtttacgt ctatacctat cagccataat attacattgg cttcatctat atactttagt
     2461 gtaatttcat gatcctctac ggatatacta ccgccagggt tatatccagg tgtgtctata
     2521 aagcagatgt ttttgtaatc tttaaacggg ttagatacta ttaaaaactg cactaaagtt
     2581 ctcatatgaa aaccaaagtc ttttatattg taatggtcaa acatacttgt gtattctggc
     2641 tttatctctt ttaatgtgtt gtttatagat gctgccttaa tatttaaact gtcaccatgc
     2701 actacatagg taggaatggc tgttgtaggg gttatgtttg ttgatagttg aaagtttgaa
     2761 ttatcattac tgaaaaaaac actatttata aaagaagatt tgccagtact gaatcctccg
     2821 catatagcta ctatgttttt actaaattta tctttgaaag ataaaacaaa ttctattctt
     2881 tctattatag attttaactt tattatggtt tttgcttctt ctttataagg tattttgttg
     2941 ataagttcga caaaatcttt ttctaataaa tttataagtt tttccggact gttatcttgc
     3001 ttttcttctt ttgatagaat aaggcttatg gcttgtaatt ttttacccaa atcgtttcgt
     3061 tcatttgtga gtattttaat ctctctttct ttcttttgat tttcttcatc taatttttct
     3121 ttttcttctt ctaaagtttg gattttgtct gccagatctg cacatttgtt cataaatgta
     3181 tcgcgttctt cttcaatctc attgtattta gagtgaagat tttttaatac taaagtttga
     3241 ttatcgtgta tcttcttaag atcttcaagc tctatcttgt aagtttcttt ctcttttcct
     3301 aaaatttcta ttgtatcatt gagtttttta tttaagtttc caatttcttc ataatctgtc
     3361 aataaattac tgtatttaag ttgtaattca ataagtttga tgtttaagtt tttgtattca
     3421 tcttcaagtt ttttattttc actaataaga ttactgtatt tttttctcag cttatcatat
     3481 tctacagata tctcttcata catcctttta aagttttttc caaaaaatac tctgtataaa
     3541 aagttcaata tagtgctaaa actcatatat aattatctct tcactctctg gaaaacttat
     3601 ttcttacttt tcctataaac tttcctttaa atacaacgtc actctaatct tagattttta
     3661 aaatagttct agtgtttacc atggcaaatt acacttcctg taatagaact tttttcttta
     3721 aattttttag ctctttcgat gtattgttta gtttgtctat cataaactgc ttagattcaa
     3781 tatctttcct taagttttct atttcaatcc tatacttgtc aaatatcgat ttgataactt
     3841 tacttccttt ttcacctaaa tttttcttaa ttgttttaga aaattcattt aagttatctt
     3901 taaattcaga ttccaggtca tctaaaaaat ctgtaagctt actacgataa tcttctattt
     3961 catcttcatt ttttaaaata cctcttcttc gtaaagaact tggaattgtg atgtcatcta
     4021 atgatggaaa gtcaatttca cttttttcta tgcttgttat actttttatc attatatctt
     4081 tgtcaataaa ttcatctcct acaacttccc ttatagtaga tgtaagctct ctacgtaatt
     4141 ttactttcca ttgttttatc gcttcttcta acttttcttc agttgaaatt ttttgattgt
     4201 ttacactttt gactaactct gcttctacat atcctgtttt caaaatcctt acattttcct
     4261 ctactttctt ttctccaaaa agaaaatcag caagaaaccc aagcaatcca cctcttcctt
     4321 cgttttttgg ctccgttttg tatccttctc ctacattttg aaggtcatat atagatttac
     4381 ttatatccat ggtgattttt ctgctgatct tttttatatc atcaatcaat tcttctacta
     4441 actcgtcata cttatgttct acaactcccg aattagatgt tttcttttgt agttcttgta
     4501 tgtttttttc gaggtctttt atctctgtac tttgtatttt tgttaatctt tcttccacag
     4561 ctttaataag accatctata tactttctaa ggctttgaga tttagctttc atgatttctt
     4621 ctgatctttt ctttaaaatc tcctgttttc tctcttttac cttttccaga gcctctacta
     4681 tttcaactat ccctgataaa agttttagat tttccagtgc tatatctttg ttgtcctctg
     4741 aaaaaaagtc tggatagtta tttgttagat ttttccagac tattttcata ttatcgtccc
     4801 acaattgttt gttatcaaaa agtttgtata aactgtagca agctccagat gatagaaaca
     4861 tcctctcttt actttcttca attaattggt tgtaagtatc tcctatttcg ggactatttc
     4921 tttttaagtc ttttatggtt ctccgtgtgt aatctgcgag gtttttcttt atattttcaa
     4981 gtgctgtaaa aaggttccct cttgatttta tcttttcatc tccatgaagc tgtaaatcta
     5041 cctggctacc taccaaaaac agctctctta taccttcttt catcgttatt ctgtccataa
     5101 gatctaaatc ttcttcgctt agaaactgtc ccgcattact caatataaaa actacgtctg
     5161 cgttttttag caactctctt gtccttgctt cccttgagac tacaggatca tttatccctg
     5221 gtgtatctac tatttcaacc cctttaagac tttctaaagg tgcttttata cgtacacttt
     5281 ttgtgtaagg tgtgtattta ccttgggaac caacataatc aaggagtttt ttacttagtt
     5341 cttcaaggct atctgccgat ataacttcat tgttactaaa attttggttt aagcctttgt
     5401 tttccatatc attgtaatgt tcatatgctg cttgaagatg gatatatttt tcaaacagtt
     5461 ccttttttgc catatcttcc gcttttttct caatgtttcc tgattgaagt tccttttcat
     5521 catttttaaa ctgttcgatg tatttttctt ttagatcgtt tagctttgtt aagtattcat
     5581 catgtttctt ttttatctcc tttacatctt tttgagtata aaactctact tcagcagata
     5641 tcttatcgtc gtaagaaagg agagtaagag atgcggtcat aggtgttgct gcttttggaa
     5701 gtatggattc cccttcaaac agtaaagcgt ttaataaaga tgatttacca gctttaaccc
     5761 ttcctacgat acctattgtg agtgttttgg aatctctatc taaatctgca agttgttttt
     5821 ctaaatcttc aagtttttct aatgcaagat cttccttcag gttttcagcg tcatctttca
     5881 aaatagtata gtttttgtct actactgctt caacttctct gaaaagtttt aatagctcca
     5941 tgattactcc tccctatgaa aggtacttat tgtaactgtc tacaatattt ttcttgatgt
     6001 tttgatattt agatatttta actgaaattt cttctgcttt ttctttaaga tttttttggg
     6061 cttgttctat cgaatctttt ttgagcctta acatattttc atattcgttt atgacgttcg
     6121 ttgtgagttt ttttatctca ttattcacaa tttctaaaag ttttggtctt agctctgcct
     6181 tcaatgaagg tataatttga gtcatgatta tagattttgc tttttctttc tgtttttgtt
     6241 ctatggatga ggatagcaac ttattgacta tgtcaggaag tgcgataata ataagctcta
     6301 aaactggagc aataaagttg gttgtaactg ctaaaattac agctgctgct ctggctgtat
     6361 ttttatactg ctcaagctta tttgtaattg aaaaaagtaa gttgtctttt aactgtgtag
     6421 ctttttctga tatccagtta gttggtatat ttacacctaa atcagaagag ttttgaattg
     6481 attttagatg tactcccaca tcatcaataa tttcagagcc tatgtcagaa attatgtttg
     6541 gaacatctac agagagcaca tttaccacca tatcgttgac tattttggag aatttatccg
     6601 ggcttgaaac tgcaatatta gccaaataat ccttttgggc tatcatctcc ctctctatac
     6661 tggacagtat cctgtttacg tttgtcgaag agtgtttact ttctatttct cgaatttttt
     6721 tgtctttttc ttttattaga gactctatct ccttttctaa ggcttttatc tctttgtcat
     6781 tttgttctac ggttttttgc atacttgata ttattgtctc tattgtatca actacctgaa
     6841 aagttttata ctttaagtcc ggtaaataca tcttttttat aagttcatct gtatttaaag
     6901 atgtaagtat tttttctaaa attttaccgc cattttctcc tacaaggtgc acttctttat
     6961 caaagtttaa gtaagtttta atatcttcct ctattttttc ctttattgct aaaacatctt
     7021 tctctgattt taaatttacc ttgtttaaga ttacttcaaa atctctctgc aaactttcaa
     7081 gaccctttaa cctgtttaaa aaagatcttg gtaaagtccc gctttctaca ctgattacaa
     7141 ctacataaaa aatacctttc cctaagtaat ttaatattgc cttgttgtgg atatcaactg
     7201 gagactcaaa tcctggcatg tccaccagaa cagcaggttg gatcctctta agatttggat
     7261 tgtttaggta aactaccata tactcgtaag cattggcttt ttcttttatc ttctcaaaat
     7321 ctgataaact gtaaatatca ggtttatcag agttatcaga catgatacac tcaatccgtt
     7381 cattttctga atatcttatt tctgtagcca atgaagtttc tggagttatt cctactggta
     7441 gatagtcagt ttctaagaaa gagtttataa ggctgctctt tccagcacta aaaggtccta
     7501 ttatgggaac tataatctct ctttgcaaaa tatcttcttt taactcatca atgtttaagt
     7561 caattgaaga tattgaatcg tgtagctcct gatctgattt aatttgagaa tcaaggatac
     7621 ttaaaaactc caccatattt tcttttacct tcatttttca atacccccta cagaatttta
     7681 aagcatttta acataaattc tgagttttta aaataacaaa tttcctgccg tcaccccatt
     7741 ttttgcactc taaaataagt tcaaagttct acgttcaaag ttcaacgttc taacgttcta
     7801 acgttctaac ttttcaacgt tttattctgg aggcttttac aaatataact tattgaaaat
     7861 tcaagatcta ataataaaaa tgggggagat gataggatat ttccttgttt agaacttact
     7921 ttttctatat aatttcgtaa aaaaggagtt tttatgagaa tgtcattaaa aatcgaatta
     7981 gaatttgatg aggatgagct tttaaagaat aaaaaaggta aaatttatgt tttattaaat
     8041 cacgtgccga ttttaggata atctggcggg aatcctctgg gtttcaactc agagatgaaa
     8101 gccagatggt aactatatgt tatttatttt tttgtttcat ttattctaaa aattatttat
     8161 ttttgctata ctatatgtat gagtaaaatt aatattaaac atggaagaac agttgtttat
     8221 aatgtgaact atcatattgt ctggtcaacc aagtatagaa aaaaagtttt gacaggcaac
     8281 atagagcaaa gactaagagt acttatgaat gagataacaa aagataaagg gtttgaaata
     8341 aaatctatga aaatcatgcc agatcatatt catgtatttg tgacagcgca tccaaagtat
     8401 tcgccgtctt acatttataa aatgcttaaa ggaatatcag ggagaaaact ttttatcgaa
     8461 tttcccgatt taaaaaaaca atcatggaga ggacatctat ggaacccatc tacttatatt
     8521 gaaaccatag gtcacatatc ggaagaaacg ataaaaaaat acatagaaga tcaaaaaaag
     8581 aaataatggt attaaaagca tacaaatata gattatatcc aacgaaagag caggcagagt
     8641 taatagaaag acacttcggg tgttgtagat ttgtatggaa ttattttctt tctttaagaa
     8701 aggaaacctg ggataaagag aaaaaacatt taagttttta tgaaatcaaa aaactgctac
     8761 ctgaactaaa aaaacaaaac ccatggttaa aagaagtaaa ttctcagtct ttacaggaag
     8821 tagtgataga acttgaaaga tcttaccaga gatttttcaa aggtatctgt aatttcccat
     8881 tatttaaaaa gaagaaaaaa tctcaaagtt tttctattcc gcaacatttc agaatagaga
     8941 gtgatagagt gtacttacca aagttcaaga cagggataaa gttcaaaaaa catagggaat
     9001 ttactggttt accaaagaga ctttatataa ccagaacacc atcagggaaa tattttttat
     9061 tagttgtatg tgaaacagaa ataaacgttt tacctgaaaa caaatacata gcaggtgtgg
     9121 atttaggcat taaaaacttt gtaactatag ccagagttaa taaagacaat acactaatta
     9181 aaacagaaaa agttccacat cccaaaacac tacagaaata tgaaaaacgc ataaaaagac
     9241 tacagagaca actatcaaga aaacagaaag gttctaaaaa cagacaaaaa gcaagaataa
     9301 aacttgcaaa aatctgggaa aaagcaaaaa atgtaaaata cgattatttg cataagttgt
     9361 cttcaaggct gataaacgaa aaccaagtta tctgtcttga agatttaaat atcaagggaa
     9421 tgataaagaa cagaaaatta tcaaaaaaca tttgggacag tgcatggtat gagtttataa
     9481 ggcaactgcg ttacaaggca atgtggtatg gaagaaaaat agcaactatt ccattatttt
     9541 atccttcaag taaaacgtgt agtaattgtg gatggatttt ttctgatatg gatttgtctg
     9601 taagggaatg ggagtgtccc tgctgtggag caaagcatga cagagacata aacgcatcga
     9661 taaatgtagt taaagtaggg atggaacagc ccgaatttat gcctgtggag gaaactacca
     9721 gggtcttctc tatgagaagg caagtggttc ctgtgaagca ggaagcgatg cacgggattt
     9781 caatcccgtg agcaggtcac gaaaatttat taaaaataaa attagtagcg aaataataga
     9841 acaattaaaa agaaatttgg aagatacttt gaatgcagaa gtttatattt tttcagagga
     9901 agattaaata aacaaaaata agacttttga aaaatttagt tctctcttct tttttacgta
     9961 atgaaataga gtgcctcccg cattcttgga gtaaaaaaat attttaacaa atgggggata
    10021 ccaaaaatgt agttatgaaa ttattgtcaa ttatttggat atatgttata tatttaaaaa
    10081 ttttatatag ggggtagtta tgccaaaata ttattgcaaa tattgtggtg caagtgcttc
    10141 ttcagtttca agtttgacag caggtagctg ttcaagaaat cctgtaaaag gtggaaagca
    10201 tgttttatat gaaggttctg aaaaatctca atacgtatgc aaatattgcg gtataaaagc
    10261 atcaactatc tcaactttga cagccggtac atgctacaga catcctaata aaggggggag
    10321 acatgaacca atgttgtgat atgaaaaaac atagttcatc gctcctgaat tttatatcct
    10381 aatttttcta aacgtattac aatattaatc taaaagacgc taaaatatag tagtgtataa
    10441 ttaatcgtgt cattgaaatc ccccttgaag ggttgtagta tttatctgca acaaacaaga
    10501 caaaaaaacc cttaaagaaa gactttgcaa tgaataataa atcaattacc aagatatttc
    10561 aagtaaatga ccactgcatt ccttccattt ttttactcta atctgcaggt aatttttttc
    10621 atctcacaaa tctaaatatc ctatcgccat tttaaataac agagacgatt tataatgaat
    10681 aaaaatgctt taagggtgat ggttgacaca attctggcat caccccattt ttatgatttt
    10741 gatcataagt ttcaataatt tatgcttgta aaaatctaca caataaagaa gaaaagtagg
    10801 ggcagacctg tgtgtctgcc ctgatgatgc atctatgggc aaacgctcag gtttgcttct
    10861 atatagggcg aacacatagg ttcgccccta cgtattgtct atgtatgcaa aaaatggggt
    10921 gacggcagtg acacaattaa gttgacatta ccaaaagttt acttgtggac taaagagata
    10981 aagaatgggg ttgaaatgtt aaaatgttaa aacgttggca cgttagaacg ttgaacgtag
    11041 aacgtagaac attgaacttt gaacatttta tgatttgaca atttatcaca ttagattata
    11101 attacttaca tagagtatta tcatctggag caaataatga aaaaactgcc aatagggata
    11161 cagactttca gcaagataag agaagaaggg tatatctata ttgataaaac cgaagaagct
    11221 tttgaactgg ttaataattt tacatacgtt ttcctctccc gcccccgcag atttggtaag
    11281 tcattatttg ttgacacatt aaaagagtta tttgaaggga ataagaagct ttttgaagga
    11341 ttatacattt acgacaaatg gaattgggat gagaaatacc ctgttatcaa gataagctgg
    11401 gcaggtgatc ttactactct tgaaagagta gaagataggg caattgatat ttttaaaact
    11461 aaccagagat tacttgggat tgaatgtgaa aacaacaaaa acccttcttc ttgttttaac
    11521 gagctgatac aaaaagctta tgaaaaatat aatcaaaaag ttgtcattct catagatgaa
    11581 tacgataagc ctatattgga tgtgattgag aatgttgagc aggcaaaaat aaacagagga
    11641 tttttaagaa atctatattc aatcataaaa gacaacgatg cttatattcg ctttgccttt
    11701 cttacaggag tgagtaaatt ttcaaaggca tcgatattca gtggcttaaa tatgcttacc
    11761 gatatatcgc tgaatccaaa atatggcaac atctgtggat atacccagag ggatattgag
    11821 acgagcttta aagattattt tgtcgatgtg gatatggaaa aggttaagag gtggtataat
    11881 gggtataatt tcttaaaaga taatgtttat aatccttttg atattctaca atttatcagt
    11941 aatggtcttg tttttgataa ttactggttt gaaaccggaa caccatcgtt tttgataaag
    12001 cttctaaaag agaggagata ttttctgcca aatttttcaa atatcgttgt ggataagaaa
    12061 cttctttcca gctttgacgt agagaatata gatcttgaag tgatcctatt tcaatcaggt
    12121 tatctgacaa tagagaaggt aattcagacc cccagaagta taggatacaa gcttaaaata
    12181 cctaatcttg aagtccagat atcgttaaat gattatatac ttagatacct ctttaactat
    12241 cgagaatcta atgatattca aaatcagagc tatgatgcat tttacaatgg tgaacttgat
    12301 gtgataagag ataaccttac gacccttttt tcatcgattc cctacaccaa ttatacaaat
    12361 aacgaactaa agctatacga aggtttttat gccagtgttg tatattctta ccttgcatct
    12421 cttggtgtgg atttgatagg tgaggatgtg acaaataagg gtaggattga tttaacggta
    12481 tttgtgtcag ataagatata cattatggaa tttaaggtgg atggtgcaaa aggtgaggcc
    12541 ttatcccaga taaagcaaaa gaactacgcc cagaagtata tggatagagg caaagatatt
    12601 taccttgtgg gtatagaatt tagctcaagt gagaggaata tagtaaattt tgagtgggag
    12661 aagttggaac gttagaacgt tggaacgttg aaacgttaga acgtgaaacg tgaaatgtga
    12721 aacgttgaaa agctggaacg ttggaacgtt gaactttgaa agtagaactt cgaacttatt
    12781 ttagggtgca aaaaatgggg tgacggaaga tcagtatgat tattgacatt gtttctatta
    12841 tattatatgt taacacaata aatcaaatat aaaattatct tggagtaaaa gctatgttta
    12901 atttaggaag gattgtaata gggataaata taaaagatgg tgatagtgta aagtgtataa
    12961 aagaggtaaa tgagtttaaa aaatatttta aagatgagta tttaatatat attttaaaag
    13021 cttatgaaag tggagtactt aagcaattct tttatggaca tggaaaagat gaaatatcag
    13081 agatgttgga gcaggcaaaa ctaaatggga agccacaatt tgaagtatta aatgatttag
    13141 ctaaaatttt gggaatcagt gaaataaaat cggaatctgt cctcaaaaat atgcgtattt
    13201 ttgataaaga aattctcctt gataatttgt tggaaaacgg aggggagata tatttgatgg
    13261 cggataccta tgattttaaa tttcaaaata gcaagctatt aaaaaatatt tttttaagag
    13321 gtagtggttt aaataaaacc ttgataaata taggagggga actttattta gatgatgatg
    13381 ttgaaatgat tatagaaaat tttgatttaa aaataattga tagtttgaag atagaaaatg
    13441 gtaaagtaat atttagaaat gtcagtatag atggtgggag tattgattta acatctacat
    13501 ttgcggaatt ggataatgtc aatgtttcat caacaataaa ctcttattct tcaaatttaa
    13561 ttgtttcatc ttctaaaatt tttggcggag agagtttaaa tctaataaac tcgcagtcag
    13621 aaataaaaaa ctctcaaatt tataaaatga atggaaatgg tattgatgct aaatcatcaa
    13681 atgtaatagt tgataatagc gaaatatatg agaatttaaa aaatggcatt gtaataaagg
    13741 agtcgtcaac attaaccctt acatcttcaa atatttacaa gaatggcagg aaagatgaat
    13801 ggtatcatca gatatgggtt gaaaactcat atgcagagat atcagattca agaatatttg
    13861 aaagcaaggg aggagcagga atttatggtg tatttgccaa aatagttata aaaaatagcg
    13921 agatatatga gaattcagga cgcggcattt ctataagaga gtcatcaatg ctaatcctga
    13981 tgtcctcaaa tatttacaaa aatggcagga aagatgaatg gtatcatcag atatgggttg
    14041 aaaactcata tgcagagata tcagattcta aaattcatga aagcaaggga ggagtaggaa
    14101 tttatggaaa ttctgctaaa atagttataa aaaatagcga agtgtatggg aacacaggaa
    14161 atggcattgg tatgatagat tcgtcaacat tgactcttac atcctcaaat atctacgaaa
    14221 atggtatgaa agataaatct tatcatcaga tatatgttga aaaatcagat gcagaaatat
    14281 cagattcaag aatatttgaa agcaagggag gaagtggaat ttatggtgaa tctgccaaac
    14341 ttgtaataaa aaatagcgaa gtatatgaga atttaggaaa tggtattaat ataaaagagt
    14401 cgtcaacatt aaccctgata tcctcgaata tttacaaaaa tggcacagaa ggtaaatcgt
    14461 atcctcaaat atgggttgaa aaatcagatg cagaagtatc agattcaaga atatttgaaa
    14521 gcaagggaag aagtggaatt tatggtgaat ctggcaaact tgtgataaaa aatagcgaag
    14581 tgtatgaaaa tttatggtat ggtattgaga taaaagagtc gtcaacatta acccttacat
    14641 cctcaaatat ttacaaaaat agatttactc aaatatatat tgaaaaatca gatgcagaga
    14701 tatcagattc taaaatatat gaaaatagga gtgaaggaga tggaatttat tgcatatctt
    14761 caaaaatagt cataaaaaat agcgaagtat ttgaaaatca aggtgtaggt ataaatattc
    14821 gacgagattc agatgcttat ttatatagtg ttgtaacata taaaaataaa ataggattaa
    14881 agcattatcc atcaatatct aaagaaaact gtgattttaa ggatggatat caatatagat
    14941 gatagaaata agtattttaa aaaattagta aggattatat aatgatggat tacagaagat
    15001 catgggaaaa aattaaagaa aagattctca cacatataaa ttgtgatgat tataaacttt
    15061 tttatgtatc aactattgaa gagacaaaag ttttaaaaat gttaggggag attgcggacc
    15121 aaaaagatgt ttttctgtat acttatgata ttgcaagtgg tttaaaatgt gacaaagata
    15181 agaggataaa aaatctttca gatgacttca aaaaagatct ctcttctgtt attgaatggg
    15241 tcgaaggaca aaaaaagggt tatcttgttt ttgttaatat aaatcagcat attgagcaaa
    15301 attatttttt aataagaaaa atcaaaaatt ttgtaaactc tataattgaa aataattatt
    15361 atataaagat ttttatggtt tctcagtttg taagaattcc agatgaactt caacatgaag
    15421 catgttttat tgatttccca ttacctacaa gagatgaaat aaaagatata gttgataatt
    15481 ttttcaaaat aatacagaat gaacctacaa aagagtttag agaacaaata attgatagtt
    15541 tgttgggact tagagaaatt gatatagtaa atgctttgaa gtttgctcta tatagtggtg
    15601 cattagataa aggagatgtc catacaataa tagatataaa aagccagatt attaagaaag
    15661 aaagccttct ggaatttatt aaaataacag aaaatataga aaacgtaggg ggtatgaaaa
    15721 atttaaaaga ttgggttttg caaaagaaaa aagttatttt taatttgtca gatgcatata
    15781 attacgggtt ggaaaatcct aaaggaattt tactttttgg gatgcctgga tgcggtaaaa
    15841 gtctggtagc aaaggttatt tctaatgaat ggaaattacc ccttctaagg cttgatatag
    15901 gtatgatact tggaccctat gttgggcaat ctgaagaaaa catcagaaga gcaataaaga
    15961 tagcggaatc tattgcacct gttgttctct ggatcgatga actcgaaaag gcttttgcag
    16021 gaatcagtga tggtaacagt ggaggatcgg atgtgatgaa aagagttttt ggttctttcc
    16081 taacatggat gcaagaaaaa acaaaacctg tttttgttgt agcaacagca aatgatatat
    16141 cggcaatacc accggaattt ttgagaaaag gtcgctttga tgagattttt tatgtggatt
    16201 tacctaataa agatggaata aacgagattt tgaagataca tcttagaaaa aggaataaag
    16261 aaagttggca tgaatttttt caagaattta tgcctaagtt gagtggtttt tctggtgcgg
    16321 atatagaagc tcttgttaaa gagataatag agctttcttt tgtgaataat atgacgaata
    16381 aaaaagatga cattagcaag tttattgaaa aaacaattgg agattttaaa cccattacag
    16441 ctacaatgaa ttcgaaaatt gaaaatttaa gaaataagat gaaagaaata aatgcaaaat
    16501 ctgtagatta gaaaaggagg attttatgaa agaaatttca ccggagttta taaaggagat
    16561 atcgagattt gcagatgaaa taacggatga attcatgaaa aatcaagata aggatccatt
    16621 ggagttttct atacaattaa ttatgaagta taaggatatt tcttatgaag aagctaaaga
    16681 ttatttgaaa agaataatag aaggtatttt gcgatacaga aatatggatg aaaatataag
    16741 tatttcagaa attacaaaag gtgaaattaa agacgagcaa cttgcggaaa taaccgaaga
    16801 tttagttgat atctctaaaa aaatgttaga atctgaataa tatttttagg gggataaaaa
    16861 tgaatgataa aaatgaaaaa aattttactt tagaggatat tataaatagt attgctttgg
    16921 taagagcaca agaagcaggg cttttgggaa atgaacaaat caaacctgaa gatgcaggaa
    16981 tactgggagc attgtctaca gatttattgg atatatttaa caaggtatta aaaaatgaaa
    17041 tatcgaaaga aaaagcatct atcgagatta aagaacatac aagtaaggca ttcaaagcct
    17101 tggtttcaaa tgtatatgac atagctacga attttgctgt ttctgcaaca aaaaaaatcc
    17161 ctattatagg ccctgttttg agtactacaa taaaagtagt agcagaaaga gcaaaaaaac
    17221 ctgttgttaa taaaattgtg gaagctggta tgaaaattgc aaaaagtgta gagaaacttt
    17281 ttgattcatt attctcataa attcagacta ttagaggctg cttcatactt tgtcgatact
    17341 gcttcaaagc ttgtatagat ttatataaac accgaccaca ttcaaagctt gcatgcttga
    17401 gaaattctca ttgcttatgc agagattcaa accattataa aacagctata tctactatat
    17461 taaaaggaca ttatagattc atgcccttgc aattaaaaga ctgaatctta aagccgtagt
    17521 atgttattta taggatattt ggcctgggta agatgaaaag aaagaaaagt ttacttgtag
    17581 actaaaggga taaagaatgg ggttgaaatg ttaaaatgtt aaaacgttgg cacgttagaa
    17641 cgtagaacgt agaacattga actttgaaca ttttatgatt tgacaattta tcacattaga
    17701 ttataattac ttacatagag tattatcatc tggagcaaat aatgaaaaaa ctgccaatag
    17761 ggatacagac tttcagcaag ataagagaag aagggtatat ctatattgat aaaaccgaag
    17821 aagcttttga actggttaat aattttacat acgttttcct ctcccgcccc cgcaggtttg
    17881 gtaagtcatt atttcttgac acattaaaag agttatttga agggaacaag aagctttttg
    17941 aaggattata catatacgac aaatggaatt gggatgagaa ataccctgtt atcaagataa
    18001 gctgggcagg tgatctgcag acgcttgaaa gcgtaaaacg ggtagccctt tataaattca
    18061 aatcaaacca ggaaaatctc ggaataagct gtgataatac aacagatcct ggtagctatt
    18121 tcagtgattt aatacataag gcttataaaa agtatggcaa aaaagtggta attctcgtag
    18181 atgaatacga taagccgata ctggatgtaa ttgataagat cgatcaggta aagatatata
    18241 tggaattttt aaaaggtctt tactcaatca tagaagataa tgaggtttat atccgctttg
    18301 cttttctgac aggtgtaagc aaattctcaa agtcatgtat atttagtgac cctgatagac
    18361 ttacagacat atcgctaagt ccaaaatttg gtaatatttg tagctgtacc cagagggaga
    18421 ttgagacgac ctttaaagac tattttgtcg atgtggatat ggaaaaggta aagagatggt
    18481 ataatgggta caatttcctg aaagataatg tttacaaccc ttctgatata ttaaatttta
    18541 ttaaaaatga atgtaaattc gacaactact ggtttgagac aggtacacca tcttttttga
    18601 taaagcttat aaaagagagg aaatatttta taccaaattt tgcaaatttg attgtagatg
    18661 acaaagtact ttttagctct gacatagaga atttaggtat tgaagctatt ttatttcagt
    18721 caggttattt gacaattgaa aaggcgatcc agacccccag aggtatagaa tataagctaa
    18781 agatacctaa ttttgaagta gagctatcgt taaacaatta tatacttaga tatctctctg
    18841 gattcgaaga ctctgcggct aacactatgt aaattcataa aaattatgtt aaaaaaaggt
    18901 gagtcgtgaa aggatttgta cacgtaaaat gatagataag tcagcgcaat ccctacattt
    18961 ttaagacgaa aaaatctggc ataattcatt ctgagaccgc ttcatgcttt gtgtaaaagg
    19021 gttatttgcg acctatgtgc ctttgtaatt aaaaattctt agccattaca atgcctttga
    19081 ttccacgctc attatttaga tactctttta ttctttcaac tgctttttcg ttgtaatacc
    19141 atacagttgc atattttttt tcggacactt tcattacaaa acctctggag tattcaagat
    19201 tcccttttaa ccccaatatg tttgtgatac gccctatttt attcttattc acaccgagca
    19261 ttctggcaat ttcactcgct gtaaaaagat tctctaaaac acaagaaact gcttcaggat
    19321 gactgtttgc aagaatcttg ctcaaaattt ctatctgcgt gtatttatcc tcagatttat
    19381 attcttcgat aaaatcttta aattcattaa gaaaaaatag actttgaata gtctttatct
    19441 tttctctggt aaagtttggc aaaattagct cctattgcaa atttttaagt ttattttgta
    19501 tttcttcaga tttaaagtaa ttttctattg ctttattgac aatatagttt attgcctcct
    19561 tgtcagataa agtttctgtt tcttctgaaa atagtgcttt aataatcgta attctcttca
    19621 tattcacttc atttacattt actctgtaac tcttttcttt ttcttccata tttcacctct
    19681 tttctttaat tatttcaaat aatccaaatc tacatcaaac atttaaattt tctcatttat
    19741 tgtcaaattt aattaatttt tattttttgt caagaaaaat gtttctttga acatgcatga
    19801 atataatatt ttctatttta ttacatacca taattataca cgagagatat tttttattga
    19861 cttggccata aatatggcta tataatatta catactacat agtatgtaat aataaatgac
    19921 gtggaggcaa aaaatgaccc caaaaccagc cgaaaatcct ataccaattt tacaaaaaca
    19981 taaagaaaac ttcctaaacg aactaaaatc acaaaattac tcaaaaaaca caataaccgc
    20041 ttattctcaa gaaatagatt actttattga attttttaga ggttttcagg atgatatgga
    20101 gataattgat ataaatcgcc cttttataca acaatctctc atttttcgtg aagaaaattc
    20161 aaaaacaggt aaaattgcca caaatactaa aaaaatgtat ctaaaagccc tatatcaatt
    20221 ttttgtatat cttaccgatg caatgaatgg aattaaagat tttactactt tatttagtaa
    20281 aataaaaata aaagcagaaa cgaggcaaaa agagtattta aatgaggtag agataaaaag
    20341 attactaaat tatataaatg tgaagaaaaa taagcgaatg agctttataa cttgcagaaa
    20401 tattcttttg attaaaattc tactttatac tgggatgaga gcgtcagaag ttataaatat
    20461 caagctatct gatataacca catatgaaca ggataaaaac atcatccaga taagaattat
    20521 tggaaaaggg aacaaagaag gattttgtta tattgatcat ctcaaaatat cagaggagct
    20581 ggaagatacc ttacttttcc gcaaaaggct caatattaca tctgaatacc tatttaccac
    20641 aaaaacaggt aggcagatga caaggcagga agctttttta gctactgcaa atattttgaa
    20701 aaaagcgggt ataaataaaa agggcttaca cctttttagg catacattgg gttttcatct
    20761 tgcacaaaag ggggtaagga tagaagatat acaggagata ttaaggcact caaatataaa
    20821 tactacaagg atatatgtcc agaggaggga agccgacaaa atcaatggga ttaaaaagat
    20881 agattattga aatcagtctg gagcattgat ttgattttgt acgagtaacg ttagaacgtt
    20941 gaaccttgaa cgtagaacgt tgaacatttt tatcatttga caatttatca tattatacta
    21001 taattattta cataaagtat tatcatctgg agcaaataat gaaaaaactg ccaataggga
    21061 tacagaattt tagggaaata attgaagaaa actatattta tattgataag actgaagaag
    21121 cctatcagct tgtgtccaac tataagtacg tttttctttc ccgcccccgt agatttggta
    21181 agtcattatt tgttgataca ttaaaagagt tgtttgaagg gaataagaag ctttttgaag
    21241 gattatacat atacgacaaa tggaattggg atgagaaata cccggtaata aaaatcagct
    21301 gggatggtaa aaataggagc atcaaagatc tcgaggcaaa cctcagggaa actttactgg
    21361 aaaatcaaaa aaaggactaa atattaaaat agtgacgacg atctggatct ggtaatctgc
    21421 tttagaaggc tcattacaga agcggctgaa aaatacaatc aaaaggtagt aatactgatt
    21481 gatgagtatg ataagccgat attggatgtg atagacgata tagagcaggc taaggagcat
    21541 agggaatatt taaaaggact atattctgta ttaaaaggtg tggatgccta cattaggttt
    21601 gcttttctta caggtgtgag taaattctca aaagcatcta tattcagtgg tttaaatatg
    21661 cttgaagaca tttcattagt tgatacattc ggcaatatct gtggctatac ccagagggat
    21721 attgagacga gctttaaaga ctattttgtg aatgtggata tggaaagcgt aaagagatgg
    21781 tataatgggt acaatttcct gaaagataat gtttacaacc cttttgatat attaaatttt
    21841 attagaaata aatgtcaatt tagaaactat tggtttgaaa ccggtacacc atcttttttg
    21901 ataaagctta tcaaatcaag aaactacttt ttgccaaagc ttacaaattt gattgtagat
    21961 gataaacttc tttccagctt tgacgtagag aatatagatc ttgaagtgat cctatttcag
    22021 tcaggttatc tgacaataga gaaggtaatt cagagcccca gaagtatagg atacaagctt
    22081 aaaataccta atcttgaagt ccagatatcg ttaaatgatt atatacttag atacctcttt
    22141 aaccatcggg aagctaatta tattcaaaat cagagctatg atgcatttta caatggtgaa
    22201 cttgatgtga taagagataa tcttacgacc cttttttcat cgattccata caccaattat
    22261 acaaacaacg aactaaagct atacgaaggt ttttacgcca gtgtagtgta ttcttatctt
    22321 gcatctcttg ggtttgattt gataggtgag gatgtgacaa ataagggtag gattgattta
    22381 acggtatttg tgtcagataa gatatacatt atggaattta aggtggatgg tgcaaaaggt
    22441 gaggccttat cccagataaa acataaaaac tacgcccaga agtatctgga taggggtaaa
    22501 gatatttacc ttgtgggaat agaatttagc tcgagtgaga agaatatagt aaattttgaa
    22561 tgggagaagt tggaacgtta gaacgttaaa acgttgaacg ttgaacgttg aactttgaac
    22621 gtagaacctt gaacgtagaa ttttgaacat attttagcgt gcaaaaaatg gggtgagggt
    22681 agagaaacaa tttagccttg acaataagga taaaagatag tatttttatc cctatgagaa
    22741 atgataaaat aaaagatata tttaaaagag tgattatcga ttttatagaa tcttctccaa
    22801 aaaaagtaat ggcaagagat tacaatatac ctcttaatag caaaaagatt gtctcacttg
    22861 ttggtgttag aagaagtggt aaaagctcaa tactctttga tatgataaat cgtttaagag
    22921 aaaaattacc aatagaaaat atcatatata tcaatttcga agatgatagg ctatatccat
    22981 tagatttgaa atctttagat tttttactcg aagcttatta tgaattatac ccatccaaaa
    23041 gagatcaaaa gatatatcta tttttagatg agattcaagc agtgcaagat tgggaacttt
    23101 atgtaagaag gatatatgat actttagatg tccaaatttt tattacaggc tccagtgcaa
    23161 aactactttc taccgatata gccacaagct tgagaggtag aacaatcacc tatgagatat
    23221 ttcctttttc ttttaaagag tacctgcgat ataagaatat agatgtcaat ctacactctt
    23281 caaagtcact tagttttata aaaaatgcac ttgcgaatta tataattaat ggaggatttg
    23341 ctgagacaat agacgaggat gaacaaatat caagaaaaat tttaagtgat tatctcgaac
    23401 ttatagtcta caaagatata atagataggt acaatataca aaacagaagc ttactcaaag
    23461 tattaaataa atactgtttt acaaatattg ccacgcttgt aagctttaat aaactttata
    23521 atgaatttaa gtcacaaggt tataagcttg gcaaagatac tattttccaa tatatatcac
    23581 atcttgaaga tgcctatgct atatttacat taccaatata tagaaattct atcaaagagg
    23641 agcaacgaaa tcctaaaaaa atatatgcta tagataatgg ttttaaaaag atttatgatt
    23701 atgctattag tgaagatata agtaaattat atgagaatgt cgtctattta catttaaggt
    23761 ctcaaactaa aaatatctac tattttaaac aaaaacatga ggtggatttt tacgcaaaat
    23821 ttcatgataa agagatgttg ataaacgtaa gtgtagatat aaaagatcaa aaaacaaggc
    23881 aaagagagtt agagggcttg aaagaagcta tggaatattt taatttgaaa caatcatacc
    23941 ttattacaaa agatgaagaa agtacagaag tgattgatag cagaaaaata tacattatcc
    24001 ccctttataa gtggttattg ttatactaac tatactatac tgactccaag aaaactggaa
    24061 gtggatggag tgtagaggtt tggtttctaa gaaatccaca ttcctactac ttacacaaac
    24121 tttgaagcag tattgcagtg ttctaacttc tctacaatcc agctacctca ttttgaagag
    24181 acaccgtatt ttaattctcg tttttttaat atcatttttt atttaattcc ttataagcat
    24241 cacaaccttt ttgtaatttc atatcacaag ctttcccaaa caattcttta gctctaaagt
    24301 aatcttgcct aacaccttgt ccttcatagt acataacacc taaattataa catccctttg
    24361 cctctccccc atcacaagct ttttggtaga actctgcagc cttgaaataa tcttgcccaa
    24421 caccttgtcc tttggcgtac ataacaccta aattattaca tcccaaagca tatcccccat
    24481 cacaagcttt ttggtagaac tctacagcct taaagttatc ttgcccaaca ccttgtcctt
    24541 tctcgtattg aacacctaaa ttataacatc cccatgcatc tccaccatca caagcttttt
    24601 ggtagaactc tacagccttg gagtaatctt gcccaacacc ttgtccatta tagtacataa
    24661 aacctaaatt aaaacatccc aaagcctctc ccccatcaca agctttttgg tagaactcta
    24721 cagccttgga gtaatcttgc ctaacacctt gtccattgtc gtacataaca cctaaaataa
    24781 aacatccctt tgcatctccc ccatcacaag ctttcttaaa tttctgaaat gcctctttat
    24841 atttcttttg atcaagcagt tttaatccat cttccactaa accagcccaa ctgttgatac
    24901 aaattgctaa aaagattaat ccgaaaagaa gaaaatttag tttttttgac atactatcct
    24961 cctgaagtat ttgttttaaa aactaagcat ctactaaaat ttaaatttat cactttatac
    25021 ataagaaatt tcttgatgtc aattgattgt gtccccacct tccccacatt ttttgaagtc
    25081 ctaaaatagg atcatcaggg cagacacaca ggtctgcccc tacttttcta ctttttcccc
    25141 ttagctaatg caaatatctt accctgcata tattatgcca gattatctga tataaccttt
    25201 cattagaatc atcgcaaata tttgaaaaat taaacccttc cttccagatt ttatgcaatt
    25261 atactacatt gtcatcttct tttaatttta attctatctc attaatatat cttttgagcc
    25321 tttcgatttc atttcttacc ttatcttttt cccttatgat gatattctca tcctccagcg
    25381 ttctttttaa cttttcaaaa ttattcacag ctgttttgat attctgtaaa atacggatac
    25441 gcttttttac ttctgttttt tgatttgtat cttttttccc actaactaat ctcttgatct
    25501 tctctgcatt tattttgccc tctaaatatt tatcaaggca ttcttcaata aattctttat
    25561 catttttcac tgatataaat aacaagaaga tagttatagg gatattcgct tcgtgcatat
    25621 acttaatatg atcaatatta aagctcaatg ggtataacaa atagataata ctcattaacg
    25681 acatgccaaa atacttttca atatcttctt tgattgtggc cactttaagg tttaaagaac
    25741 tcttaccatc attaattttt atcaattctg acaatatatt atctatactt ttatctatgc
    25801 ccaccttttc ggctaagaaa tcctgcatta gctcaaaaat ggcagttgat ttttcgtata
    25861 acgtcaaatc ttctcttctt acattttctt caaattgcat tatcttcttt tcattttcac
    25921 ttctcgaacc caatacgtga accgtaattt tattaatacc taactttttg caagctaaat
    25981 atcgtctttc acctgcaata attttaaaca tttgtgtttt atcgtctaac tccacaagga
    26041 taggattgat caagccatac ttctttatag actcagctaa ttcttcaata cccttttcat
    26101 caaatttttt tcttatctgt tcatcggcaa ctattttatc tataggcact ttaaccatat
    26161 ttgtttgata cagatcacca cttaaaatat ttgtggctct tgatttatta aacatattat
    26221 cttttttcat cgccatccca ccttatccat tttactcttg aatcaatctc attaagaagt
    26281 ttcttggcat tttcaataga tttttgcccc cttacctgct tatagtcagt taaaatatat
    26341 ttcctttcca acaaagcctg tttataatca acataatcat ttaatacggt atctataata
    26401 taatccccat agctctcttt tacaaatgca acaaaatcat tatcataact gttttgtttt
    26461 actttattta tcactacacc tacaaaattt aagtttttat tgattaaaga ggaagattta
    26521 aatgtggcta tcattttatt taacccagtt aatccaaatt cacccacatc agttacagta
    26581 agcaaatttt ctacagacat taatgcaaat tgtgatggta aaaagtcaac tccaggcgga
    26641 gtatctataa taataacatc gtaatattta tacgctattt ccaacaaaac cttgaataca
    26701 agatgggata atggaattgt tttagacatt ttattgctta tttcaccaaa ctcaatatcg
    26761 ctggctatta cagcaaaatt ataatcaatc tgtaattcat cattctcgtc attatattta
    26821 aacggaatta aactatccaa aaacttcttt tccaactcca tccttgtttc ggaatattta
    26881 tctacaactg tatttatgtt attaattata taatcaagta gcgtatataa gtttttatga
    26941 cgcatatcag caagtaatgt ttgttcagca aaatattgac aggtatttac ctgttggtaa
    27001 tcaagatcaa tcattaaaac ttttttattt ttaatctgcc tatagtactc gccaagcata
    27061 agcgctaatg ttgtttttcc tgtcccacct tttacatttc ctatataaat acttgttttc
    27121 atagtttacc cctacactct tattattata tccaatactt ccttgtgttt ttcattattt
    27181 ttttcaattt cttcttcaaa ctctccataa ccactatggg cactgacttt acttatttta
    27241 aatacctcgg atatggcttg aaatgaaaaa tcgtggtatt tatttaaaac gtaaataatt
    27301 gcatttctta ttatctttaa ctcactacct tttttaagac gtccttgaat ttcagataac
    27361 cttatgctaa atttttcaca cattctttca actaaataat ttatcctatg attttgattg
    27421 tttattttta acttttcttt tagccccata ttatcagcta attccatgat tgcagagttg
    27481 atattgttat gtaaagtata tttttctaat aactcgttca taatgccatt tatataccta
    27541 aaatcacctc tgtgtgaatc aataattatt gctaaaatat cttgtgaggt tttatttaat
    27601 tcttcaaaat cgatttgtaa tgaatatttt aacactcttt tggcaaacaa taatttcaga
    27661 ttaaatgatg gctcagaaat atagatcata ttcgacttta atctggaaac aaatggactt
    27721 cctaaaacaa catcaccatt tttattcaat tcaaaataac tgcctgtggc attatccgca
    27781 agctctttat tcagtttgat ataatcaggt tgaactggag tagtaattac agtcactttc
    27841 tcttttacca cccttaaatt gatcaaatcg taaatcaact gaatataaac agggcgattg
    27901 gtatcacaaa taaaggataa gtcatctata gcgataatat ctgctttgtt tatttccctt
    27961 aaaaatattt ctaattgccg cattgatgag tattttttaa ttaactcaac ccagtaactt
    28021 ttgacaaaat aatatgctga cttcccctca tacttttcac taaaagcatt taacatggct
    28081 gaaacaaggt gagtttttcc cacacctgtt ggcccataga gagttataat ttttccacca
    28141 tagttgcctt cagctactga tttcatagtc atataagcac tatgatttgt agaatctact
    28201 aagtaattat caaaactgta ttttgtgttg aatgagtctg cttgtgatat aattatattc
    28261 tttggtaaag tgtattcttt ttctataaaa ccatcttcgg ttttaattgt atttattatc
    28321 ttttctgctt gaaaaataat atcctctatg tcataagcaa taataacatc tttgagtaaa
    28381 tccatcattt tttctttttc attcttgagt ttttctataa taaacgatga ggcagtagct
    28441 ataatttttt tattttctaa tgtaaacttg gttgacaata ttcctataat aaaaagaata
    28501 ccatattttt cgttgtaggt ttctccatct tttttaattt cattttgtat gtactcgatg
    28561 tactctgaaa attccatttt atcacccatt ctttagtata atagtaacat agttttattt
    28621 aaacaactat tattattatg tcaacagaaa attgttagtt tattttatgc gtagtatata
    28681 acttatttac aaataagaaa atttatattt tattggcgtt agttttagtg ttagttttgt
    28741 gttagtttta atgttagttt ttgttaagtt tgttagttta cttctaaaat aatgaaaaaa
    28801 tggcctaaaa ctaacgaaaa cctaacgata agctaacggt aaaactaacg atttgttaat
    28861 agaaaaagat tattctcatt ttcaacgtcc ctaaaaaccg aagatatcgt cagcttgatt
    28921 attttaacaa gttcttatca agaagtctct atcttctata agatggagat gaattgatgg
    28981 ttgacaaata atcagtttag aattatatta tttcttataa ataaagtaaa acttgacaca
    29041 aataagcatt cagtttatct gctgtattat catcttgttt tagtggtaaa gtatagaaaa
    29101 aaggtcatag atgataggat atctaacaga ctaaaagaaa tatttgaata catacaacca
    29161 aattacaaca taacactaat tgagtggagc cacgatgaag atcatgtgca tatcctattc
    29221 aaagctaccc ctacatcttc attagctaaa tttataaatg catacaagag tgcatcttca
    29281 agattgatta aaaaagagtt tcctaaaatt aaagaaaaac tatgggataa atacttctgg
    29341 tcaagaagtt attgtctatt aacaagtggt ggagctccag ttgatgttat taggaaatat
    29401 atagaaaatc aaggaaagaa aaatgctaaa agcgtataga tacagaattt atcctgataa
    29461 agagcaagaa gaatttttca ctaaaacttt tggtgcttgt agatttgttt ggaataagat
    29521 gcttgaagag aagttaaaat tccttgatag aaaagaaaaa ataccaataa taacaccagc
    29581 caactataag aaagaatttc tatttctaaa agaagtagat agtttagcat tagctaatat
    29641 ccaattacaa aatgaaaaag cttttagaga ttattttaga aatcctaaac attttaaact
    29701 accaaaattt aaaaataaaa aaggtaagca atcatacacc acaaacaatg taaaagttga
    29761 ttttgaaaaa gggttattat ttctaccaaa aatcaaatct ggtattaagg cttgtttcca
    29821 tagaaccttt acaggaaaaa tcaaatctgc gactataaca aaaactaaaa caggaaaata
    29881 ctttgttagc attcttgtag agatagaaca acaatgtaat atccaaccac cgaagaatga
    29941 agtctgcgga atagatttag gcttaaaaga ttttgcaatt attacaaatg agaaaaaaga
    30001 aacgatcaaa ataccaagtc caaaacattt agtaaaagca gagaaaagat taaaaagact
    30061 gcaaaatcag ctatcaaaaa agcaaaaagg ttctaaaaat agagaaaaac acagagtaag
    30121 attgtctaag ttacatgaac atgtttctgc tgcaagaaac gatttcttac ataaattatc
    30181 ctttgctatt attcgtgata accaaacgat agtagtagag gacttaaacg ttaagggtct
    30241 atctcaaagt aatctatcta aaagcgttct tgatagttct tggggtaagt tcttaaacta
    30301 tctaaagtac aaagcagagt ggtatggtag aacgattata gttgtagata agttctatcc
    30361 gtcatctaaa acttgtagtg tctgtaactt tatcaatcat agactaacgc ttaaaaatag
    30421 gcactggact tgtgaagagt gtggaactta tcacgataga gacataaacg catcagtaaa
    30481 tctgatgttt tatggaatga agaaagtagg gatggaacag cccgaattta cgcctgttga
    30541 ctgtgctctg gcggcggaac tgaagcaatt caggtctacg agtcatcaca ggatgaaaca
    30601 ggaagccacc acttctataa gtggttggta gttcacatac accataaccc aataatccca
    30661 aagtctcttt ctaatcggct tttaagaaaa aaatgggcta tttgggctat ttaggctatt
    30721 taggctattt aggttattta ggctatttat cccacttatt ggaggtaaaa aaatttcttt
    30781 caacaaaagc ccctacttct ccatactaga tacccactga cttttttcac ccctctgtta
    30841 gggcaggaaa tgggtctatt ttgcaagata gatatggagg cttttaattg taaccccctc
    30901 acaaaaaatt cgttataacg aaaaatatgg ccttatagcc atatctttat aaaaaaagat
    30961 tattatggtt tataaaaaag gtgaaaaatt atggaaaaaa ttttatttcc cctttttgta
    31021 aatattgtaa tatattgcat ggctaaaaaa agatatttat tagcaataag ttgtaaattc
    31081 aaatacgagt ttttgattgt taaatacgag ttttggggtg taaaatgcga ggttttggtt
    31141 gttaaaacga aaaatatggc ttctggtgta acatttcatt ctggaggttt ggatcatgga
    31201 aaattttatt ttttaagttg tgaatctccc tggacttgag tcataagctt ttgcttgttt
    31261 atttagtctt cgtgatctac taacttcacg ggcataactt tggataagct tttcattttt
    31321 gcaatgacat tttcttatat atcgataatt acactgattg gaataatgtt gcgtttatgt
    31381 tatgtactaa ttgaggatca aaagatatgg tagtgtataa ttaattgtgt cattgaaatc
    31441 ccccttgaag ggttgtagta tttatctaca acgaacaaga taaaaaaccc ttcaaaggag
    31501 gactttaaaa tggataatat aataataaat gaattatcca aatatttcaa gtcaatgata
    31561 caagaaataa tgctaagtga aagagaaaaa tacttgaaag aacactcaga aacaagaggg
    31621 aatgggtact acataagaac acctaaaact atattgggcg atatggagct tgaaatacca
    31681 agaacacgtg atggtaattt taagccatcc ataattccag agcggaaaag agttactttt
    31741 atgttagatg atgtgataag agcattgttt actgctggct taagctcgag gaagacagga
    31801 gaagtaataa gaaaccttat gggtacttct gtatcagctt cgtttgtaag ttcaaattta
    31861 gagatatcag aagaagttat aagtaaattt atgaatagag aacttacaga aaattatcct
    31921 gtaatttaca tagatgccac ttatatttcg ttgaagaggg ataccgtatc taaagaatct
    31981 gtttatgttg tgttaggtct tagtacagat ggcagacgtg aaatattgac atattgttta
    32041 cctggtggag atgagaaatc atcggtatgg agagatatct ttataaattt gaccaacaga
    32101 ggattgagag gtgtaaaaat ggtcattagt gatgatttac ctggtatagg agaagtaatt
    32161 aaagaagtat ttcccaatgc cgaccatcag ctttgctggt ttcatttgaa gaaaaatatt
    32221 aagaataaag tcagaaaatc agattttgat gagatattaa aagaattgga gtatgtattt
    32281 gaatctaaca acgaagatga agctaaaagt cggctacatg cctttatcaa caaatggagc
    32341 aagctttata gatactttaa taacttgaga gataaaataa atagttattg ttactttttt
    32401 aaatttcatc ctaaattaag gagttatttt agtaccacaa attggttaga gagatgtttt
    32461 aaggaactta aagacaatat aagaattagg gggtattttc attctgaaga gagtgcaaat
    32521 aagtttttat atctattttt tagtgataaa agtttaaaat atcatgagag aaaattaagg
    32581 tactcaaata taatagagga gactcttaat ggataaaaat gcttcaaggg tgatggttga
    32641 cacaattaag ttgacattac cgggagtagt catttacttt aaatattttg gtaatttatt
    32701 tatcattata ttatccattt taaagtcctc ctttgaacgg ttttttatct tgttcgttgt
    32761 agataaatac tgtaactctt aaagggggat ttcaatgaca tgactaatta tacactaccg
    32821 aatcaccaaa gattagcatt gcatcgaagc agatttttga ttaattttac aataaattgc
    32881 tatttatatt tttttacgat ttttaaaaaa ttctaaaaaa tcaactaaag gttcgatgca
    32941 aaaaaattaa aattttcggg ggttgatttt tttaagaaat tttattaaca tgttaatata
    33001 gtaagcaaat ttaatattta aacagcacca tgatattttg ggtttcatct gaaccatgtg
    33061 ggatttaaag gtttcttcca ctttctttac ttcttcttgt atttcagttt catctgaacc
    33121 atgtgggatt taaagttaaa tattcaacac gtatgtcttc aataatgttc gcgtttcatc
    33181 tgaaccatgt gggatttaaa tcagggtacg taagggcagt tttggacgtg gggttgagtt
    33241 tcatctgaac catgtgggat ttaaattatg tcaccggtga tcatccaact atgggagaag
    33301 caagtttcat ctgaaccatg tgggatttaa agtcgaagaa aatggatttt agagaggttg
    33361 gcagagagtt tcatctgaac catgtgggat ttttaaagct tgggacaaaa aatgggggca
    33421 ttcacccacc agctattttt aaaaaagctt tttcattgtt gatttagata ttttcttacc
    33481 gtttctgggt caaaagactg caagtcttta gggtgatata tttatgcagg attatacttt
    33541 aatcttgtgt ctgcttgctt tccaacatgt ccaatatctt gtatgacatc cttaggtctt
    33601 gcaataaaga ttctatctct gagtccgtca agagtactga accgcagaag gtaattcgtt
    33661 cttcattttg aggttctttt gcttgttcct gcgatgtctg ttcatttgag gattttttcg
    33721 acttcttgac tgccatattt ttcctccagt gtagatattt actcaggtat tattcttaat
    33781 atatctgaat ttcctacttt tgtcaaacca aacgcacttg ctgccgtcac cccatttttt
    33841 gcacctctaa aataaaaaat aagttcaagg ttctatgttc aatgttctat gatcaacgtt
    33901 ccaacgtttt aacgtttcaa cgttctaact tttcaacgtt ttattctgag agctgttacg
    33961 agcatatctt attgaaaata cagtgttaaa tcataaaaat ggggtgatgc caaagttgaa
    34021 taaaccttga catatcattg ttaacatatt ataatttttt attgaatttc aaaatacata
    34081 atggatatat aaaaggttaa aataatgctc agcaaagtat ataaatgccc aaatcacaca
    34141 gaatatcaaa gcaaaaatgt caacaacgag gatatattta attatttaat tgaaaagtta
    34201 aaagctaaaa ctatccttca tcataaaaga gcgattcttt taaaaggaga tgttttaaat
    34261 aacaactatt ttgagaatga catttttgat ttgatagtta catcgcctcc ttataatgtt
    34321 gatatcaaat ataatacaca taaagataat atttcttatg aagaatatct tcaattctca
    34381 gaagcatggc tgagcaattg ctataaatgg agtaagaaac aagcacgctt atgtttaaat
    34441 attccactag ataaaaataa agggggacag cgaagtgtag gtgcagatct tacaatactt
    34501 gcccaaaaag tagggtggaa atatcactca acaattattt ggaatgaagg taatatctca
    34561 cgtagaacgg cttggggatc atggttgtca gcatcagccc catatgttat tgcacctgtc
    34621 gaacttattg taattcttta taaagaagaa tggaaaaaaa ctcaaggtac aagaatatca
    34681 gatatttcaa aagatgaatt tatgcaatgg acaaacggtc tatggacatt caatggagaa
    34741 agcaaaaaaa gaattggtca tccagcacca ttcccattag aattaccata tagatgtata
    34801 aaattattta gttttgtcca ggatatagtt tttgatccat ttgctggtag cggaactact
    34861 ctcatagcag caaataatac taacagatat tcaattggat tagaaattga ttcctcatat
    34921 tgtgagttgt caaaacaaag ggtattacaa gaaagtgaaa tgttatttta actatgtaga
    34981 tatattatgg taaaagaaaa aactattact gatttaatca ttgaattttt taaaaaacat
    35041 cctaaagaag atatgccaca tgggccagta gttgattggg tcgaagaaca atattccaaa
    35101 ttatataata gaaaaccacg agacacatgg cgttcaatac gtcgtttgca tcaggaaggg
    35161 tttttgataa aagtaaagaa aggtatttat agatatgatc cagatttagt agctgataag
    35221 catcttgaag agttttccca agaattaaaa aatcagattt taaaacgaga taactataaa
    35281 tgtgtaatat gtggacgtac tgctaaagaa ggatatgaat tgcatataga tcatatttta
    35341 cctaaagata agggaggaaa agctacatta gacaacggtc aaacactttg ctcaatatgt
    35401 aattttagaa agaaaaatta taatcaaacc gaaagcggca aaaggatgtt cattcgtttg
    35461 ctaaaaatcg caaaaaaaat tggagatatt gaaacacaaa aattttgtga agaaatatta
    35521 aaaatttatg aaaaatacaa tataaatgga catatagagt gggatgattg acttcctcct
    35581 ctttctttag aaatgaggag agactgctac atactttgtg tgaaatggtg atttgctttg
    35641 attgcaaaat caaatccacg gtcagatggc cagtaattct tttattttta actacaaaag
    35701 ccctttacaa tatttgaaag aatttgggga aaggtaagaa aaaaagataa attgcagaaa
    35761 aataatctta actttttgta cggaaaaatg ttgcgtttat gatctgaacg caaaaatatt
    35821 caaataccat tcgagcattt tatgccttta tgaagacagg agatggatct attttaaaag
    35881 atggagctgt gataactaat cacaccataa caataccaaa aattctttaa aacgaaaaat
    35941 atggcttttt tgccataaga ttggtcgcaa gcataccccc agctgtatat ttactttcaa
    36001 aaaaggattg acaggtttac aaatggttaa ttttatagat agaagaatcg ggatttacac
    36061 aaatcaggtt acagggtctt tggaagtttt gatctttttt cctacaaata ataaacatgg
    36121 ttgacaaaaa gaaattgttt tttattttta aatctgttgc aatagcatta cctttcccac
    36181 tatttttttc ttttctaatt atttttataa gattagaatt aatagtaagc tcaacagggt
    36241 taacagaacc atcgtctatt atgataattt cttttatatc atattttagt agtttatagc
    36301 aaattgcctc aattacagcg ttgttttcgt tataagcagg aatcaagcaa ctaaacataa
    36361 atataagact tccatatttg acttttaaca aaacctaaac gtattaccaa ttagacataa
    36421 aaatcttcat aagttttaaa aactatttat ttttgaaaaa acaaagtaaa gaaacaatgg
    36481 gatacaaatt gccataaaga acgtcccaat tattccaatt atttgttcta accttaattt
    36541 ctttttagta tagtaaaagc catctctctc aatccttttt tctaataatt tttctacaaa
    36601 atgattttta tttacatgcc tcataaaaca cctccatatt atctattttt taccaatcga
    36661 aaacaacaaa aaaccaagga caaaacccaa aataatagca aaaagtgtaa atttgtatgc
    36721 ttgcaactct aatttagatt tatactcaac tatatcctca agagaacctg gccttatttt
    36781 tctttttttt atttcaccgt tttccataag cacctcctac acacatattt tataattata
    36841 tacataatta attcgatttt ttttgttttg tcaaggtatt aattctgcca tcaccccatt
    36901 tttatgattt aatagtgaat tttcaataag ttatacttgt aaaagcctcc agaatgttgt
    36961 atgatgattt tagacaaaaa agcaacaata acaacaaact ggaggtactt tatgatatat
    37021 gaaattgcag aaaatgtgaa gagaaaaatt ttaatcctaa cacaaaacct taatgattac
    37081 attacaagac cccaacagaa atatctgatt gaaatggttt caggtgtatt tgcaaccaag
    37141 agcctgaatc ttacatcgat agcaggttat ttaaatgaga gatgtggtgt aaaacaccct
    37201 ctaaagaggt tgcagagaaa tacgttaagt ttccagacga gcggatgaaa atatttggat
    37261 ctaaagagat aaagaatggg gttgaaatgt taaaacgttg aaaagttagc acgttagaac
    37321 gttgaacgta gaacgtagaa cattgaacct tgaacatttt atgatttgac aatttatcac
    37381 attagattat aattacttac atagagtatt atcatctgga gcaaataatg aaaaaactgc
    37441 caatagggat acagactttc agcaagataa gagaagaagg gtatatctat attgataaaa
    37501 ccgaagaagc ttttgaactg gttaataatt ttacatacgt tttcctctcc cgcccccgca
    37561 ggtttggtaa gtcattattt cttgacacat taaaagagtt atttgaaggg aacaagaagc
    37621 tttttgaagg attatacata tacgacaaat ggaattggga tgaaaaatac cctgttatca
    37681 agataagctg ggcaggtgat cttactactc ttgaaagagt agaagatagg gcaattgata
    37741 tttttaaaac taaccagaga ttacttggga ttgaatgtga aaacaacaaa aacccttctt
    37801 cttgttttaa cgagctgata caaaaagctt atgaaaaata taatcaaaaa gttgtcattc
    37861 tcatagatga atacgataag cctatattgg atgtgattga gaatgttgag caggcaaaaa
    37921 taaacagagg atttttaaga aatctatatt caatcataaa agacaacgat gcttatattc
    37981 gctttgcctt tcttacagga gtgagtaaat tttcaaaggc atcgatattc agtggcttaa
    38041 atatgcttac cgatatatcg ctgaatccaa aatatggcaa catctgtgga tatacccaga
    38101 gggatattga gacgagcttt aaagattatt ttgtcgatgt ggatatggaa aaggttaaga
    38161 ggtggtataa tgggtataat ttcttaaaag ataatgttta taatcctttt gatattctac
    38221 aatttatcag taatggtctt gtttttgata attactggtt tgaaaccgga acaccatcgt
    38281 ttttgataaa gcttctaaaa gagaggagat attttctgcc aaatttttca aatatcgttg
    38341 tggataagaa acttctttcc agctttgacg tagagaatat agatcttgaa gtgatcctat
    38401 ttcaatcagg ttatctgaca atagagaagg taattcagac ccccagaagt ataggataca
    38461 agcttaaaat acctaatctt gaagtccaga tatcgttaaa tgattatata cttagatacc
    38521 tctttaacta tcgagaatct aatgatattc aaaatcagag ctatgatgca ttttacaatg
    38581 gtgatcttga tgtgataaga gataatctta cgaccctttt ttcatctatt ccatacacca
    38641 attatacaaa aaacgaacta aagctatacg aaggttttta cgccagcgtt gtatattctt
    38701 accttgcatc tcttgggttt gatttgatag gtgaggatgt gaccaataag ggtaggattg
    38761 atttaacggt atttgtgtca gataaggtat acattattga atttaaggtg gatggtgtaa
    38821 aaggtgaggc cttattccag ataaagcata aaaactacgc ccagaagtat ctggatagag
    38881 gtaaagatat ttaccttgtg ggtatagaat ttagctcaag tgagaggaat atagtaaatt
    38941 ttgaatggga gaagttagaa cgttagaacg tttaaacgtt gaaacgttag aacgttaaaa
    39001 cgtgtgaacg ttagaacatt gaacattgaa cattgaactt tgaacgtttt atattataat
    39061 tatatacata aagcattata atctggagta aaaaatgaag aagctaccaa taggtatatc
    39121 aactctacaa tctataagag aagataactg ctactatgta gataaaaccc ctttcgttaa
    39181 aaaattagtt gataacggca aatactattt cttaagcaga cccagaaggt ttgggaaatc
    39241 tttgcttgta gatactataa aacaggcttt tttaggaaat agggagctat ttaaaggatt
    39301 atatttagaa aataactggg attgggagaa aaagtatccc gttatacata tagattttgg
    39361 tggtggagta gttcaagatg cacaggacct taaagagtgg ataataaaac agttaaaacg
    39421 tcatatgata acctacaacg tatcagtaga agaacaaaac aatgcaagat ttatttttac
    39481 tgaccttata attagtctga aagagattta caaaaaccct gtcgtagtgc tggtggacga
    39541 gtatgataaa ccgatccttg acaatataga tgatacagaa aaagccatcg agataaggga
    39601 agttttaaaa gacttttaca gcgttttaaa agcttccgac cagtacttaa aacttgtatt
    39661 cttaacagga gtgtcaagat tttcaaaggt ctctatattc agcggtttaa atcaacttca
    39721 agatattacc ctatcccctg cctttgcaac aatctgtgga tatacccagt cagaacttga
    39781 gaccgtattt tcagacaggt tggaaggagt agagttagaa aagctaagat attggtataa
    39841 cggctacagt tggcttggag ataaagttta caatccattt gatgttttgt tatttctaag
    39901 tgagaaaatt ttcagaccct actggtttga gacgggaaca cctacatttt tgatggaaat
    39961 tatcttaaac aataaagtat ttttaccaaa acttgaagaa ataaaagcaa gcgatgaaat
    40021 acttgccaac cttgatgtag actttttaaa aattgaaaat ttactatttc aatcaggcta
    40081 tttaacgata aaggaaacaa aaaaattagg tttaaagaca atttatattt tgacatatcc
    40141 aaactttgaa gtaaaaatga gtttcaacaa ctttttcctg tcagacatac ttccagtagc
    40201 atcagacaaa gaagaagttc aaaacagtat agtagaagct atagaggaaa acagtttaga
    40261 aaacctaaaa acagcgttat acagtttctt tgcaagcata ccaaacgact ggtacaggaa
    40321 aaatgattta gacagctatg agggatttta cgcttcggta gtgtatgcac tttttacagg
    40381 aagtggatta aatacaagat cggaagatac gacaaattta ggaaaaatag atttgacggt
    40441 cttatatcag gatagagcct atatcataga atttaaagta gtagagaaag acagtgaagg
    40501 caaggcttta ggtcagataa aagagaagag gtattatgaa aaatatacag acagttgccg
    40561 tgagataaac ctgataggta tagagtttag taaggaaaaa aggaatgtag tttattttga
    40621 atatgaaacg ttagaacgtt agaacgttag aacgttggaa cgttggaacg ttagaaagtt
    40681 agaacgttga actttgaaca tattttaggg gtgcaaaaaa tggggtgacg gcagtgacac
    40741 aattaagtta cagtgtcttt taaagtcctc ctttgaaggg ttttttatct tgttcgttgt
    40801 agataaatac tacaaccctt caagggggat ttcaatgaca tgattaatga tacgctaccg
    40861 aataattttt acgttgtttc tattttattc acgatcttat ttgctataaa agataaaata
    40921 attatcataa ttaataagat acaaaaatct gtcgtagaga tagtttttaa tagcaaagaa
    40981 cttcttatta ggtgagtaga atatgttaac gggaaaatat gtgcaatgta ttttataatg
    41041 gatggcatct tatctacggg ataaaatgtg ccagataaaa aaatcatagg tgtaataaaa
    41101 aatgtattaa agctaaattg gtctccgtgg ttttttacaa ctaatgcaat aataaaacca
    41161 agtaaagaaa atgtaatcaa atgcatcatt aatgatataa aaaaataaaa atttatgctt
    41221 aatttaactc ctattataaa gctataaaag ataacaataa aaccaggcat taaccctttg
    41281 gtaataccat aaaaaacttc acccaatata atctgccact ttggaattgg agcaagtaaa
    41341 aattcatcaa atactttgaa ataaaacctt gaaatattaa tttcggtaga tattccataa
    41401 gcttgattca tagaactcat ggtaattaat ccaggcagta aaaatgataa ataactaaag
    41461 ccatttatct ctgaattcct gcccactcca tacccaaaag ctagtaaaaa taaaagtggt
    41521 gagatggcac tagataatat tactttccac aatcttgatt ttaaaaccaa taattctcgt
    41581 aaatatacac cataaaaccc atttatcata tatctatttt tttcccggtt aattttagat
    41641 acacatcttc aagattaact tctctaattt ttgccatatc aacgtatgta agttgtttta
    41701 atctttctat cgcctcagtt ttagattcaa aatattcttc tctcgttttc ccttctataa
    41761 atatttctaa agcatatttg cccatttcgt tttttaaatt ttctggttta ccatgtttta
    41821 taatttcacc tttatcgata aaataaacat aatctgataa gagctcagct tcttctatat
    41881 aatgtgttgt tagtaccaca gtacagccaa aatttttatt tatgtttttt acaaagtccc
    41941 aaatatgtct tctcgttgca ggatcaagcc caacagttgg ttcatctaag aacagaatct
    42001 ttggtctatg caaaatagcc cttcctatga caagtcgcct tttcattcca cccgacaatt
    42061 tcccggcttc cttattttta tgattagtta aaccggtaaa atttaaaatt tcttcaattc
    42121 ggtttttaat ttcatttttc ttaaccccaa ataaaattga atgaattagc agattctggt
    42181 aaagggttaa gtctttgtct atgttattat actggggaac taaccctatt atacttttaa
    42241 ttttattgct attggttagg aaatctaagt caccataata tatttctcca tcatcaggtt
    42301 tgagtaaacc tgctaatata ttgattgttg ttgttttacc tgctccgttt ggcccaagga
    42361 gtgcagtaat agttttgtct tcaattctaa aagtgatatt ttttaaagct acactgttac
    42421 catatttttt cataagatta ataattttta tttgcatttg atgaaaataa ttaaaaataa
    42481 tcaaattttc aagaatttat tgaaaaaatt tttttattat gatataaatt tcttaggcac
    42541 aagggaagtc cggtgaaaat ccggtgctgt acccgcagct gtaagctgga cgaaagccca
    42601 ttatgccact gccaggcatc tattcaatat ttggatgctg ggtgggaagg cgggcaagta
    42661 ggatgaaggc aagccagaag acctgtgtct catccatatt atggttgaaa gtgtccccgg
    42721 gtattgggac cggagtgctt tagttattcg gctctccggt cttaaaacga ggctggagag
    42781 tagaaatggt taaaaaagca gttttaatag catctgataa aagtggctcc ggtaagagtc
    42841 ttttcacaat ttttttgtca aaatatttta ctttaaagca aaaatctgta ttacctttca
    42901 agtgtggccc tgattatatt gatacactcc acttaaaaaa tgctactgga aataatgcat
    42961 ataatttaga cactgtattg ataaataaga aaaaattaag atataatttt ttatcaaaac
    43021 ttaatagcta tgatatggca gtaattgaag gtgtcatggg cttttatgat ggaataaact
    43081 ataaaacttt cgctggtagt acctacgaag tggcaaagat gctcaatatt cctgtattat
    43141 tcatcttaga tacaagttct acatctttta caattgctgc aaggataaaa ggtttggtaa
    43201 gtttaggtga agatattaat gtggccggtg ttgttttgaa taatgtaggt tctgaaaaac
    43261 atgaaaaaat gctaataaac gctatagagt atcacactga tttaaaagtt tttggtgcta
    43321 ttccaaaact gaaagatttt gttttacctt caagacattt aggtatttat acagcttttg
    43381 aagtaaaaga taatttttat gatgatattg ttaatacttt ctcaaattat gttgatgcag
    43441 gaaaaattta tgataataca gactatatca ttgatgaaat aactaaagat aagaagtcaa
    43501 taactaaaga taaaaaagct tatattgcct ttgatgaagc atttaatttt tattatcatg
    43561 ataatatcga ttatcttgaa gagaatggat ttcaagttat caatttctcc cctttaaaag
    43621 gtgaattacc tgaaaagcct gactttatat attttggtgg gggatatcct gagctttatg
    43681 ctgagcaact atcaaaaaat aataatctga aaaactacat aaaagaaaca tctaaaaagg
    43741 gcttgccaat ttttgcagag tgcgggggga tgatgttttt atcgaatggg ataaaagtaa
    43801 agaataaatt ttttgaaatg tgtggagtat ttgatgtaaa tgttgaaatg actgagaaaa
    43861 ggcaagcctt aggttatgta aatgttacat cattaaaatc tactggtttt tttgaaaagg
    43921 atgaagaatt catcggtcat gaatttcatt attccaaaat aaaagagtgc aatgaaaatt
    43981 atgtatttaa aatcaaaaaa gtaactgaca atagtattaa ctatgatggc tttgtaaata
    44041 ataacactat tgcaagttac acccattttc actttttaag tgacaactgc ataataaaaa
    44101 atataataaa aggagtgtaa gatgaaaaaa attatcattt ttatttttgc agcgttgttc
    44161 ttatcgaaag gagttagtat ggctcaaatg gaaaaaaagg aaacagaaaa aaacaagaca
    44221 gaaaaaaatg caattgtaat tgcaagcttt ggcacgactt acccttcggg actaaaatct
    44281 attatcaata ttatcaatat ggttaaaaat gaatttcctg ataccgaagt tagagtaact
    44341 tttacttcaa atattataag agaaatatgg caaaaaagaa ataagcatcc tgaagagtgg
    44401 ataaaaaaag gtgtgccaaa agagatttta aatgtaaaag ggattgtggc tacattgggg
    44461 gagttatccg atgaaggata caaaaatatc gttatccaat caacgcatat ctaccatggt
    44521 gaagagtttt ctgacctttt agaatatgca agagctctaa attccattca gacaattaaa
    44581 aaaagatgga agccatttca caaaattaca gtatctcgcc cagcacttgg aacttatggt
    44641 gataaaataa attaccatga agatataaaa aaggcagtaa aagcattaaa aaatgatgtg
    44701 gaattggcaa gaaaacataa tgctgcgctt gtctatatgg ggcatggaaa tgaattttat
    44761 tccacaggta tatattctga gacagaaaaa gagtttaata ttcaatatcc tgatgtaaaa
    44821 acatttatag gggtggtaga aggttatccc ggtcttgatg atttaatgga aaaattaaaa
    44881 gaacaaaaag ttaaaaaagt cattttaaaa ccatttatgg ttgtagctgg agatcatgcg
    44941 ataaatgata tggcgggtga tgaacctgat tcctggaaaa atgttttaaa taaagaaggg
    45001 atagaagtta tccctgtaat tgaagggctt ggttcaaatg atgattttgc aaggattttt
    45061 ttagagcatt taaaagacgc tatcaatgat ggtgaaatta ttcttaaatg agtagattga
    45121 tattagcatt gatagttact attttgatat tttctttttc tttgaccaat ggggcagtaa
    45181 gtttggatag tttgacaatg aagttgttat taaatgtaag attaccaaga gttttgacag
    45241 cttttatcat aggggggatg ctttctcttg gtggttctat tttgcagttg atattaagaa
    45301 atccactggc agatggattt accaccggca tctctgcatc agcagcactt ggtgcagtaa
    45361 taaatattgt gttgggatta aacatcttat ttaccccgat tattgcaatt ctatttgcaa
    45421 taatcggaat atatataatc ttcaagctta ccagtattga taaatcattc cactatacca
    45481 ccattatact ggctgggatt attttaaata taatatgttc ggcgattata agttttttga
    45541 aatattactt tgatgaatct ttaggttcaa ttatttattg gttgatgggt ggattttatg
    45601 atctatccta ttcaaaagtt tttgtcctct ttctggtgtt actttcaagt ctttttattc
    45661 ttcttaaaaa tagttttaaa ctgaatatct tagcctacga ctataagact gccagctcac
    45721 ttggtgttga tgtggcaact attagaaaaa aactttttat aattgtttcc cttctgatcg
    45781 cctttgccgt gagttttagc ggtattattg gttttgttgg ccttattatt cctcatatgg
    45841 taagagggct ttttaaacct gatatgaaaa tccacttgat ctattctaca ttattcggtg
    45901 caaattttct tttgttatct gatacaattt gtagaatgat tatcccttct ggggccgaac
    45961 tgcctgtggg tgtagccaca tcgttttttg gtgggatttt tttcttattt ttaatgaagt
    46021 atagattaaa aaatatctgg tatggataaa atgaatacca tagatatcaa aaatttgaat
    46081 gccagagttg gagattttac attaaaaatt gatagtctaa ctgtatcaaa aggggaaaaa
    46141 atagcactat taggggaaaa tggtgcagga aagagcacat tacttgatat catcagtggg
    46201 gttaataaaa attttacagg tgaactaaat atattaaaca aacaaatttc taactataaa
    46261 cccatcgagc ttgcaaattt aatctcttat ttacctcaat tttctgaaat catttttgga
    46321 tttgatgtct ttgatactgt tttattcgga agatacccca aaacttctgg taaatttgag
    46381 gattatgatt ttgaaaatac taaagagtgg ctaaaaaaac tggatattta tcatttgaaa
    46441 gatagaaaat tcaatgagct ttctggtgga gagaaaaagc gagtaatgct tgcgagagtt
    46501 ttaaaccagg acactgatat tattcttctg gatgaaccct tttccatgct tgatgtaaag
    46561 catacaaaaa tagctaaaga gattttagta aatgagaaaa aaagcataat actatcatcc
    46621 catgatataa atatactaaa atatttggta gatgagatag tttttttaaa aaaaggtgag
    46681 gttctttgca aagtaaatat agataattta aacaaggaga ttttaaatga agtttttgaa
    46741 gtggatttta aatgtattga tgggttttat tttgttaact aatagctgta tagcttatga
    46801 aagggtaatt ttgttgtccc cagcctgcgc tgatattttt gctgagctgg gattaaaaaa
    46861 taaagttgtc ggtatcacaa agcatgtaaa aggttttgat aacgctattg aagtgggatc
    46921 tcatttaaaa ccaaacttag aattaatgct ttctttaaat ccagatttga ttatttattc
    46981 aaatgatcat tttttaccag acagatttga taaatttaac ataaaaacat acagatatga
    47041 cccaaaaact gttgatgaaa tctttgagca aataaaagag atagcttcta tgatgaatgt
    47101 gtctgaatcg ggaaatagtc tgatatttaa attaaaaagc aaattatctc agttaaaaaa
    47161 gctaaataaa aagcctaaag taatatatga agtcacacaa acaccctata tagtagcagg
    47221 taaaaacagt ataataaacg atattataaa acaagctggt gggataaatg caatagatat
    47281 caataaaaaa ctcgttaaat tttcaattga aaaagccgtt tcactaaatc ctgatatata
    47341 tatttatcaa ataggtccta tgaatgaagc cccaacttct ccggaagaaa ggcctatttt
    47401 caaaaatatg ggaactattt ttatcaaagt aaatgaactt gattttgcaa gagcaaacac
    47461 aaaaacgata gataacatcc tttttttgaa taacatcttt tacaaatgga gcctgaaatg
    47521 agaaaactta tcttgatagg tgcaggatta aacaaagact tgatgacatt aaaaggttta
    47581 aacaagctta aagaggcaga catcatcctg tacgacaggt tggtggataa tagtttattg
    47641 gaagctgtaa attgtgaaaa aatattcgtt ggtaaaacac cttacagacc aggctgttcg
    47701 caatgtgaaa taaatagctt gatagaaaga gctcttttag aaaataaaac agtggtcagg
    47761 ataaaaggtg gggattcttc catatattcc agaagccttg aagagatcga agtggcccga
    47821 aagtgtaatg ctttaattga aattgttcct ggagttactg cggcatcaca atttgtcgca
    47881 aaattagaaa cagctcttac tgcaaggggt atctcttctg gtgtgatttt cataacgggt
    47941 cataaaaaag atgttgaact taacgaagca tacaactgga aagcaatcgt tgatttaaaa
    48001 atgactattg tggtatatat gggtattaaa aattttatga aaatattaaa attgttggta
    48061 gagaatggtt tacatgaaaa aacaccaatt gctattggcg aaaaattaga ttttgaagac
    48121 gaaaatatca tagtgtcaga tgttgaaaac ctgctaaact ccaattttga tattagattc
    48181 cctgcaatat tactgattgg agaagtggtt aaattttcta aattttttaa aaatagcatt
    48241 accattaaaa atgaaaggtg tataaaatgc gcaaattaat tcatgcaatc ggtttaggtc
    48301 ctggagatcc agagtctatc aatttgaaag ctttagctac tttaaaaaat tcagatgttg
    48361 tagttactcc tgaatcagat aaaaatggca gaagtctggc aaaagagatc gtcagcaaac
    48421 atatttcttc ttcaaaaatt ttcacatatt atttccctat gaataacgat aaaaatttac
    48481 ttgataaaag atacaaagag ttagctgaaa ttatagataa ttttttatct gaggggaaaa
    48541 aagtttctta tgttacaatc ggcgatcttt ccatatacag tacttttaat tatcttgaga
    48601 aaaaattaaa actctttgac atagatgtaa ttaagattcc tggaattcca tcatttattg
    48661 ctgctgcaaa tagaattaac gaaagtttag tggtaaaaga tgagcctttt tgcgtggtgg
    48721 agctttcaaa taatttagat aaattggatg atttattaag taatttcccc acagtagtga
    48781 taatgaaagt gtataaaagg ttaaatgagc ttgtagcttt tgttagaaat agtaatttag
    48841 taaaaaaagg atttttgata gaaagggcaa ctctaccaga agagagggtt tttgacctat
    48901 taacagatga tatacctgaa gaagctggtt atctatccac cgcaatactt tttagcaggg
    48961 ttaaagatga ataaagggtt atcaatagaa aaagaaagct ttgatattat agagcagaat
    49021 gttgatttat cgaaatacag tgatgaagaa aaagttgtag taaaaagggt tatccacgca
    49081 tcaggtgatt ttgattttgc taaaacaatt attttttccc ataattggct tacagactct
    49141 aaaaaaatta ttcaaaaaaa accagcagta gtatgcgatg taaatatggt aaaagctgga
    49201 attacagaaa aatatttaaa agttagtggg ctaacaacac actgctttat ttccgatgaa
    49261 aagattcatg agcttgcaat actcgagggg aaaaccagag ctgagacttc tattgagtat
    49321 gctttcaaaa actttgataa tataatattt gtcattggga atgctccaac agctttattg
    49381 aaggttttag aactgaatag tttatatacc gataaaaata tattcgttgt tggatttcct
    49441 gtgggttttg taaaagctga agaatcaaag gaaatactta caaaaactga tataccattt
    49501 ataacaaata aagggacaaa aggtggtagt ggcattgctg cagcagcttt taatgccctg
    49561 ataaaggtat gttttaatgt gtaaaaagat actgatatta ggtgggacat ctgatactga
    49621 aaaatatcta aatatatgta gtaaaaatga gtttataatt tctgtagcca ctgaatatgg
    49681 gtataaaatc ttttctaaaa agtttggtaa agatagagtt attttaaaac gatttgacga
    49741 aaaaagttta gaagatttta tcaaagaaaa tagtatttat aagattatag atactactca
    49801 tccttttgct aaagagatta caaaaattgc taaagatgct gcaaataatt taaatataat
    49861 atatgaatcg atgataaggg aaaatgagat aaatataact tacgagaagt tgatatatgt
    49921 aaattcttta aaagaagcca taacattttt aagagagaat gattttaaaa agatcctgct
    49981 aacaattggt agtaaaatga taaaacattt ttcattctta aatgaaaaag ctcatgtcag
    50041 aatactccca tttgaacaat cgataaaaga tgtattggag gctggatttg attatgataa
    50101 aattatagca attcagggtc cattctctaa agattttaat aaagctatta ttaaggagtt
    50161 tgaaatagag ttgttggtaa cgaaagtaag tgggcaatct ggtggttatg aagaaaaagt
    50221 agaagcctgc agggagatgg ggattttttg tcttgctatt aaaaactggt agataaataa
    50281 agggacgatt acatgaaaaa agataccaga gtatactgac cccaagaacc ctggacattt
    50341 aaaaaaagag atgagaaata aggtagtatg atctctatac ttttaggaca aacaaatgta
    50401 ttgacagatg gggtgaagta ccccactggt gaaaaaatcg aaacagttat atcagttata
    50461 ggggtgttaa ttggataatt tctcacatgg cggtaatata tattattacg ctaacctgat
    50521 cggatgtaat cccaatgaga tcattgatct aagtagtaat atttcccctt ttgtggatga
    50581 aaatatattt gaattcatta aaaatcagct atcaaatctg aaaaatttac cttcctcaaa
    50641 tgcttttatc ctaaaagaag ctcttgctaa aaaatatgat aaagatatgg aaaattttgt
    50701 tgttggtgta ggaacaagtg aaattataaa aaatttatgt ttaattaaca gtggaaataa
    50761 agccctgata atagctccaa catatatcga ttatgaaaaa tattgcaaac tttataacct
    50821 tcatacaagt tttcatttta ccagtgaaag gaggaatttt gctattaatt tacaagaatt
    50881 agatttttca aaattcgaca taactttcat ttgcaatcca aacaatccca caggttacta
    50941 tatacaaaaa gaggaaatat taaaggcagc taaactgttt gaaaactgct tattcgttat
    51001 tgatgaatcg tatctgccat ttatgatcga tagtgataat gcaagtttac tttttgaaaa
    51061 aactaaaaac attattgtat taaggtcatt ttcaaaaatt tacggacttg cgggtctaag
    51121 aatcggctat gctttctctt ttaataaaga taatatcaga gaaattgaaa agcattgtct
    51181 cgaatgggga gtaagtagtc taagtgaggt agtgggaaaa taccttcttt cattagaaac
    51241 agatcaaatt gcatcaaaaa ttaatgaaat taaggggtat ctatatgaag aattaaaatg
    51301 ttgtaataac attaagccgt taccatcctc tacaaatttc cttctaataa aattaactca
    51361 tctaaatagt gaaaaggttt tcaataatct tttatcaaat aaaattttaa tcagagattg
    51421 caagaacatt agagggcttg atgacttatt tattagagtt gcaataaaag atttagattc
    51481 tatgaaatat ttcttaagtg tttttaaaaa gttagtgggg tgtaaaaatt aaaaacataa
    51541 tggttcaggg caccagttcc aatgtgggta aaagcattat aacagcagga atctgtagaa
    51601 tgcttgcaaa taaaggttac aaagttgccc cttttaaagc gcaaaatatg gcattaaatt
    51661 ctggagtgac ttttgatggg ttagaaatgg gtcgagctca gatattgcag gctgaagcat
    51721 gcaagatttt accagatgta aggatgaacc ctattttact aaagcccaca ggggatggta
    51781 aatcacagat aattagactt ggaaaacctt ataaaaccgt ttcttacaaa gactattatc
    51841 aaatttatga agaaaaccta aaaatagtaa aagaagcatt ttattcatta tcaaaggagt
    51901 ttgacataat tgtattggaa ggggcaggct cacctgcaga aattaacctc caaaaatttg
    51961 atatagtaaa tatgaaaatg gcagagattg cccgtgcgaa ggtttatata gtgggtgata
    52021 tcgatagagg gggtgtattt gctgcattta agggcaccta tgatttaata cagcctcatt
    52081 acaaaaaatt tgttaaaggg tttattatca ataaatttag aggggatcta tctcttctaa
    52141 aacctggtat cgatgggttt aaagattttt gtgacatacc gataataggt gttattccat
    52201 attttgagca caatttagaa gatgaagatt cgcaaaatct ttttacgaag aaaaacaaaa
    52261 aaagtggtga aatattattg aatattggaa taataagatt accctacatg tctaatttta
    52321 ctgacttcca atgtcttgaa aatattgaaa aaatcaatgt agagtatttt acaaaacctg
    52381 aaaactcaga aagttatgat ttaattatca taccaggttc taaaaatacc atctccgata
    52441 tggattatct gttaaaaaca ggtttttatg agcagattaa aaaattatat ggtaaaaaat
    52501 ggattatggg aatttgtggt ggttttcaaa tgcttggtaa aaaaattatt gatagtttaa
    52561 atgttgaaaa taaaggtgaa atagaaggat ttggctttat agatatgatt actgaaatga
    52621 aagaagaaaa agtattgaaa ataggtgaat atctaccagc aaatgatttc ttaaataaaa
    52681 gtatctgtgg atatgaaata catcatggga atacgattat taatgatagg gatgtaatag
    52741 atatgttgga aaatgaatct ttactcgtct ttaataagga aaaaagaata attggcactt
    52801 atttacatgg gatttttgaa aattctaatt ttttacagtt tattttcaac ctgtttaaca
    52861 aacagataga aataaacaaa acatataaag tgataaaaga agaaacattg gacaaacttg
    52921 caaatttaat tgaaaagaac ctccttgggg acattattaa tgactaacat attggtgtta
    52981 gcaattctga tagatatagt ctttggtgag ctaccaaata aaatccatcc tgtggcaatt
    53041 atcggtaagt taatatcagt gtatgagaat attttttaca acctcaaaaa caaattttta
    53101 ggtggttttc tactgttcat ctcaacacat attacaataa ttactgtcat ctttttcctg
    53161 ttaaagattt taaaatcaaa ttatctacta tttcccctta aggtctttat tgtatactct
    53221 ttaatttctg ttagggggat gatagaccat gcaatgaaaa tttatcaagc tttatcgatt
    53281 gacatcaatt tagcaaaaga aaatttgaaa ctaattgtta gcagagatgt agacgcaatg
    53341 aacgaacagg atattataaa atcatcgatt gaatccatag cagaaaattt ctgtgacgct
    53401 ttttttgcgc ctatttttta tggagtaatt tttggtattt atggtattat tttttataga
    53461 gttacaaaca cattggatgc gatggttggg tataaaaatg aaaaatatat ggaatttggt
    53521 aaattttctg ccagaagcga tgatattcta aactttatac cagcaagatt acagttgatt
    53581 attttattgc cagtttcaca aattttattc aaaaatggat taaactcatt ggaaatctat
    53641 aaaaaattca gaaatacatt atcaagccca aactcaggat gtggaatatc cctttttgca
    53701 ggagcactaa atataactct tggaggggat acatattatt ttggcaaatt agtaaataaa
    53761 ccattgataa caggtggtgg cgatttactt acaaaacaaa aactcctgga tgccattttc
    53821 ctatatttgt atagtgcaat ttttactgta ttgcttatta ttatttttca attattatgg
    53881 agtcaaaatg ttccctttaa tctttaaatt atctgataag aaattacttt ttataggcgg
    53941 tggaaatatt gcaaaaagaa aacttttatc tattttgaat caatcaaacc ctgaagtgac
    54001 aataatttcc aaagaattac atccggatat aaaaaagctt ttatcaacga ataagataac
    54061 ctggataaag tcaagcttta aagaggaatt attaaaacaa aaatacgatt tagcttttat
    54121 ctgcacagat gataaagaat taaatacaaa agcagcttta attttaaaaa agataggaac
    54181 tcccacaaat atatgtgaca acaaagagtt atcagatttt tttactccag caattgtttc
    54241 tcaagacgac attattattt caatctcaac aaaagggaaa tcgccagctt ttgcaaaaca
    54301 gttaaaagag gtaatatcaa aaaccttaaa agagttaaaa tgaaaacagg gataacaaca
    54361 ggcacagcag caacagcagc agctaaaggc gctttaatct ataaattgac tggaaaaatt
    54421 gagaaagagg tggaagtaat tttaccttat gggtgctcta taaaaattcc tctaattttt
    54481 aaaaataatc ttgtgggtgt aaaaaaatgg agtggagatg accctgatgt cacagatggg
    54541 attgagattt ttgcatctgt aaggatgttg aatgaaaacc gaattataat aaaaggtgga
    54601 gaaggtgtag gtattgttac gaaacctggt ttacagatac ctgttggtga ggccgcaata
    54661 aatccagtcc ccaaaaaaat gatagaaaaa aatttaaaaa ctcttttaga caataatcaa
    54721 ggagtagaag ttacaattat tgtgccagag gggagagaaa ttgctaaaaa tacctttaat
    54781 aagaggcttg gaataataga tggcatatct atcatcggga caactggaat tgtgaaaccg
    54841 atgagtgtcg atgccttgat tgaaagtttt aaatgtgaaa ttgatgtctt gattgcacaa
    54901 agatacaatt ttttgtggat agttcctgga aatattgggg aaaaatgttt attacaagag
    54961 aatattacgc catcggttat ggtgagtaac tattttaaag agtctttcga gtatcttaaa
    55021 gatagaaata tcaatgagat aggtgtagca ggacatccag gtaaaatagc aaagcttgcc
    55081 atggggtatt ttaatacgca ttctaaaaat tcacctcagg caaaccgatt tgtaaaagaa
    55141 gttttaaata tcaatcacga ttttaataca atagaagagc tgtgtaacag ctattcgttt
    55201 gataagatag cttatttagt tagcaaaaaa ataaaagaaa aatttgattt tacaaaagta
    55261 tcggtaaaat tatttgatat gaaatgcaac aaagtaggag aatatcttga ataaaaatat
    55321 ttatataatc tctgctggtt gtggtagcaa agactatctt acattaagag catttgaaac
    55381 tgctaaaaaa gttgattttt tgataggtgc agaaaggttt aaagatctct tcccggataa
    55441 aaagtatata attttaaata atctcataaa agataccatc aacatattag agaatgaaaa
    55501 agagaaaatt gtgggtgttg ttgtatcagg tgatgctggc ttcttctctt tggctaaaat
    55561 aatttataaa aaattcaaaa acagaataat cgaggtaata cctggtattt ccagtatgca
    55621 gcttggtatg gcaagaatgt ttaaaacata tgaaagtatt gagtttttct cattacacgg
    55681 tagaaatatc ccaattgaaa attttgaaaa aaagatagat aaatgtttac agcaaaaaaa
    55741 agatctttat gtattagatg ataaaaataa acaatttttc gagttgttat ccagatcgaa
    55801 agagatttta agccttttcg atatttatat tttaaacaat ctcggtttac cagatgagac
    55861 tatatataaa ttaaaaacta taaatgattt aaataatata aaattagaat tatattctat
    55921 ctatctggag gtaagaaata aatgaacaaa gtttttttta taggtgcagg tcctggagat
    55981 cctgaattaa ttactgtaaa agggatgaaa atacttacta aatcagatat tataatctat
    56041 gcgggttcac tggtaaataa acaaattctg gagtatgcac cagcaggctg taaaatttat
    56101 gattcttcaa aaatgaattt aacgcagatt atagaaataa tagaaagaca ccatcttgaa
    56161 ggaaaagtta ttgcacgatt gcacacaggt gacccttcaa tttatggtgc aatatatgaa
    56221 cagatgttag aacttgataa aagaggtatc ccttatgaga ttataccagg ggtaacagca
    56281 ctatttgcag cagcagcaaa actaaaaata gagctaacag cccctgaaat ttcacaaaca
    56341 ttgactattt caagagttga agggaaaaca gcggttccgc aaacagaatc attagattta
    56401 cttacaaagc atggtggaac attttctttt tatctatcag cttctaatgc agagaggata
    56461 aaggagactt ttttaaaaaa tgggtggaag gaaaataccc cggttgcaat atgttataaa
    56521 atttgctggg atgatgaaaa gattttaaat accactttgg gtggtttagt taacacactc
    56581 aaagagaata acattaaaaa accatactct tattataatt ggcaagattt tggatagaag
    56641 tagtatagtt aaatattcaa agttatacga tgaggatttt gaacatggat acagaaaaaa
    56701 agattgcagt aatagcaata actgaaaaag gggcattatt agctaacaaa atatctgatg
    56761 aactaaatgg gattttattt ttacccgaaa aatttcgggg aaggattaaa gctacttatt
    56821 ttcaagaatt acaagagatt tgtaaattct gttttgataa tttcaagggt attatagcag
    56881 tgatggcaca agggattgtt acaaggatga taaatgggct catcaaaagc aaatatactg
    56941 atcctgctgt agtggtttgt gatgaggtgg gtagattttc tatcagtatg ctatctgggc
    57001 atgaaggtgg ggcaaacgag ctaacctttc tggtaagctc aattacaggt gcagagccag
    57061 tgataactac agcaagcgag gcaaataaaa tttatgtggt gggtataggc tgtagaaaag
    57121 gggtagataa gcagactgtt gttgaagcaa tttcttattg ttcaaaatta gctaatattt
    57181 ctataaatga cataagggtc attgtttcct gctggcacaa aaagaatgaa acaggtttga
    57241 tcgaagctgc aaaagagtta aattgctatc ttagattttt accaaaagag atatataata
    57301 atgagttata ctgttttaaa gaatcaacag ccaaaaaata tttagggatt aaaagtgtag
    57361 ctgagccatc agctttactt gctgcacgaa atcctatttt agttttaaac aaaaccattt
    57421 ttaatggtgt tactatagca attgcaaagg agaatttaat aaatgggtaa attatttgtg
    57481 gtaggtattg gccctggcaa acatgacctt ataaccagaa gaggattaga cgctatttta
    57541 tcaagtgatt taatctgcgg ctataacaaa tatatcgaac tgcttgactc tttagtttgt
    57601 aataaaccta tcttttcaaa tggtatgaaa ggggaaatag aaagggttaa gtttgcaata
    57661 gacaaagcaa aatctggcaa aacagtatct ttagtatgtg gtggagattc atctctttat
    57721 gctttagcgt cacttgtttt tgagttatgt gacgattttg aaaatatcga aattatacca
    57781 ggcatcacag ctgctttatc agccagtaca aaacttggtg ccccaatctg tgaagatttg
    57841 gtaatccttt cactatctga tttacttacc ccttttgaaa tcataaaaaa aagggtagac
    57901 gctataaata ttggtgattt tgtaacagca atttacaatc ctaaaagtca aaaaagggat
    57961 aagtatttaa aagaagtatt ggaatcattc tatcaacaaa ggggtgattt aatttgcggt
    58021 atagtaaaaa actgtgatag agatgatgaa cttgtaaaaa ttacaaaaat taccgacttt
    58081 gactatgaca tcgtggatat gtcaactgta gtgattgttg gcaacactaa aagctatata
    58141 aaaaatgata aaatgataac cccccgaggc tacttaataa aatataacag atagttatac
    58201 ttacttccct actgcattta aaaatactct ttgtcgagaa tgcggtattg gaaggattat
    58261 aaaagctctt tgatctgata ctatcgaata attctaaatt ggcaatggtt cttgctatct
    58321 tcaataatct gtgaatagct tttgctgata aacccatctt tgttattgta tagtatgaaa
    58381 aaagtgtaga gattatgctt taaaaggtga ataactggca ttcccccatt tttacgatta
    58441 gttcttgatt ttcaataagt tatacttgta aaagccttag aataaaacgt tgaaacgttg
    58501 aaaagttaga acgaataaac gttagaacgt ttaaacgttg aacatagaac attgaacgtt
    58561 gaacttagaa cgtagaacgt tgaaccttga acttatttta gggtgcaaag atgggggagg
    58621 gcagaagaga ttctgtctgt aagtttatga ttattgtaat atactttgta gaaatgataa
    58681 aaatatttgc tgacaacaaa ttgcaaatct aaatact
//
