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The map label for this gene is aer [H]

Identifier: 38234670

GI number: 38234670

Start: 2173043

End: 2174347

Strand: Direct

Name: aer [H]

Synonym: DIP2121

Alternate gene names: 38234670

Gene position: 2173043-2174347 (Clockwise)

Preceding gene: 38234665

Following gene: 38234671

Centisome position: 87.32

GC content: 57.85

Gene sequence:

>1305_bases
ATGGAACGCGTAGCGCCAAACGGCCAGTTTAAAGATGTAGGAGTGGACCAATTATTCTTCTCCACCACTGATGCCCAAGG
GCGCATCCAAGAAACGAACAACACGTTCGTTGAGCTTTCCCGCTACACCGAAGAAGAGCTCCGCAACGCAGCACACAATA
TTATTCGCCACCCCTTTATGCCCGGTGGTGTTTTTAAGATCATGTGGGACAAGCTCCAGCGAGGCGAAACCTTTGCCGGC
TATGTGCGCAACCTTGCCCACAGCGGAGAAACCTACGATGTGTTTGCCACCGTCACACCCATCCCTGGCACTCACGATTA
CCTTTCGGTTCGCCAGCGCCCCTGCCATGACGACCACCGCGCACTTGCTATGACCATTTACGCAGAGGTCGGCGACTACG
AGGCCCAGCTGCGCAAAGATGGCATGTCAGCCCGCGAAGCAGCCGAAGCTGGAGCAGGTTTAATTGGCGATAAGCTGCGA
GAATCTGGTTTTGACAATTTTGACGCTTATGCGCACGCAATGTTGCCATGGGAGGTTTTCTGCCGCGAAAACATGAGTAC
GGGCCTCCCCCAGCGCGAGGTCGCTGGCGATTTGGGCACGGAGTTGGCTCAGGCGCATGATGTTCACGACCATCTCGACG
AATGGATGTTGCGTCTCGACGAACTACTCACCACCGCTCAGCAGCTTGGCGAAGCCCGCGAAGAGCTCGTCGATTCGCTC
GGGCAGACCTCATCGCTAGGCGATACTATCGACGCCCGCAGCGCCAGCGAAACATTGCAGATAGTCCAGTTCCAGCTCAA
CGTATGGAAGGGCATGCAAAAGATCGTCGATAGTTATGTCGTCGAACTCGCCGAGCTCATCACCACCCTCGCGAACGACA
CCCTGCGCGAACGCTTCCAGATCTCCGTCTCGCGCCTGCACACCGCCATGCTGGCCACCTTCCTCGCCGAGCTTATCGAC
GGCACCTCCGCCACCGCGAACACCGAACACAAAGTAGCCCTGCTCAAAGCCACCATGCGCGATTCCTTGGAAGCCATCGA
CCGTGGGGCCTTCCACCGTGCCCAACTCGTTCGAAGCACCATAAGCTGCATACGCACCGTCACATCGCTCATGGAAAGCC
CCCGCAGCCTGCTCACCGAGGCGATCCGCGAGGCCCAAAGCCTCAACAACGACGAGCTCAGCGCCGCGATTGCAACCGAA
CTCGAACGCTCTGAACGTGCCGCCAACAACATGCACCAGCTTGTTGCCACCCTCGAGAGCACCGCCACAACCCCCGATAT
TGCCGCTATGCTCGCAGAACTCTAA

Upstream 100 bases:

>100_bases
CCACAGAGCTGAGAATGCTGTGAGAACAACTATTGTATTCACTTGACATCGTGATACATACGGGGATCACCCCCACAGGA
TCGATCATGAAAGCGGGAGC

Downstream 100 bases:

>100_bases
AACGCTTCAGTACCTTCCTCTGTGCTGAGCTGTGGCACTATGGGTAGCTATGACATCCCGCGACAGTAATAAGAAAGATC
TCCCCTCAGCGTTGACTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MERVAPNGQFKDVGVDQLFFSTTDAQGRIQETNNTFVELSRYTEEELRNAAHNIIRHPFMPGGVFKIMWDKLQRGETFAG
YVRNLAHSGETYDVFATVTPIPGTHDYLSVRQRPCHDDHRALAMTIYAEVGDYEAQLRKDGMSAREAAEAGAGLIGDKLR
ESGFDNFDAYAHAMLPWEVFCRENMSTGLPQREVAGDLGTELAQAHDVHDHLDEWMLRLDELLTTAQQLGEAREELVDSL
GQTSSLGDTIDARSASETLQIVQFQLNVWKGMQKIVDSYVVELAELITTLANDTLRERFQISVSRLHTAMLATFLAELID
GTSATANTEHKVALLKATMRDSLEAIDRGAFHRAQLVRSTISCIRTVTSLMESPRSLLTEAIREAQSLNNDELSAAIATE
LERSERAANNMHQLVATLESTATTPDIAAMLAEL

Sequences:

>Translated_434_residues
MERVAPNGQFKDVGVDQLFFSTTDAQGRIQETNNTFVELSRYTEEELRNAAHNIIRHPFMPGGVFKIMWDKLQRGETFAG
YVRNLAHSGETYDVFATVTPIPGTHDYLSVRQRPCHDDHRALAMTIYAEVGDYEAQLRKDGMSAREAAEAGAGLIGDKLR
ESGFDNFDAYAHAMLPWEVFCRENMSTGLPQREVAGDLGTELAQAHDVHDHLDEWMLRLDELLTTAQQLGEAREELVDSL
GQTSSLGDTIDARSASETLQIVQFQLNVWKGMQKIVDSYVVELAELITTLANDTLRERFQISVSRLHTAMLATFLAELID
GTSATANTEHKVALLKATMRDSLEAIDRGAFHRAQLVRSTISCIRTVTSLMESPRSLLTEAIREAQSLNNDELSAAIATE
LERSERAANNMHQLVATLESTATTPDIAAMLAEL
>Mature_434_residues
MERVAPNGQFKDVGVDQLFFSTTDAQGRIQETNNTFVELSRYTEEELRNAAHNIIRHPFMPGGVFKIMWDKLQRGETFAG
YVRNLAHSGETYDVFATVTPIPGTHDYLSVRQRPCHDDHRALAMTIYAEVGDYEAQLRKDGMSAREAAEAGAGLIGDKLR
ESGFDNFDAYAHAMLPWEVFCRENMSTGLPQREVAGDLGTELAQAHDVHDHLDEWMLRLDELLTTAQQLGEAREELVDSL
GQTSSLGDTIDARSASETLQIVQFQLNVWKGMQKIVDSYVVELAELITTLANDTLRERFQISVSRLHTAMLATFLAELID
GTSATANTEHKVALLKATMRDSLEAIDRGAFHRAQLVRSTISCIRTVTSLMESPRSLLTEAIREAQSLNNDELSAAIATE
LERSERAANNMHQLVATLESTATTPDIAAMLAEL

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=101, Percent_Identity=40.5940594059406, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 48231; Mature: 48231

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVAPNGQFKDVGVDQLFFSTTDAQGRIQETNNTFVELSRYTEEELRNAAHNIIRHPFM
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PGGVFKIMWDKLQRGETFAGYVRNLAHSGETYDVFATVTPIPGTHDYLSVRQRPCHDDHR
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCHH
ALAMTIYAEVGDYEAQLRKDGMSAREAAEAGAGLIGDKLRESGFDNFDAYAHAMLPWEVF
HHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCHHHHH
CRENMSTGLPQREVAGDLGTELAQAHDVHDHLDEWMLRLDELLTTAQQLGEAREELVDSL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQTSSLGDTIDARSASETLQIVQFQLNVWKGMQKIVDSYVVELAELITTLANDTLRERFQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISVSRLHTAMLATFLAELIDGTSATANTEHKVALLKATMRDSLEAIDRGAFHRAQLVRST
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISCIRTVTSLMESPRSLLTEAIREAQSLNNDELSAAIATELERSERAANNMHQLVATLES
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATTPDIAAMLAEL
HCCCHHHHHHHHCC
>Mature Secondary Structure
MERVAPNGQFKDVGVDQLFFSTTDAQGRIQETNNTFVELSRYTEEELRNAAHNIIRHPFM
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PGGVFKIMWDKLQRGETFAGYVRNLAHSGETYDVFATVTPIPGTHDYLSVRQRPCHDDHR
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCHH
ALAMTIYAEVGDYEAQLRKDGMSAREAAEAGAGLIGDKLRESGFDNFDAYAHAMLPWEVF
HHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCHHHHH
CRENMSTGLPQREVAGDLGTELAQAHDVHDHLDEWMLRLDELLTTAQQLGEAREELVDSL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQTSSLGDTIDARSASETLQIVQFQLNVWKGMQKIVDSYVVELAELITTLANDTLRERFQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISVSRLHTAMLATFLAELIDGTSATANTEHKVALLKATMRDSLEAIDRGAFHRAQLVRST
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISCIRTVTSLMESPRSLLTEAIREAQSLNNDELSAAIATELERSERAANNMHQLVATLES
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATTPDIAAMLAEL
HCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]