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The map label for this gene is sdrE [H]

Identifier: 38234619

GI number: 38234619

Start: 2111093

End: 2112964

Strand: Reverse

Name: sdrE [H]

Synonym: DIP2062

Alternate gene names: 38234619

Gene position: 2112964-2111093 (Counterclockwise)

Preceding gene: 38234620

Following gene: 38234618

Centisome position: 84.9

GC content: 47.22

Gene sequence:

>1872_bases
ATGGCTTTAAATTTCAGAAGAAGAAGTCGGGTCTTGGCTATTCTTACCTCCTTGAGTGTCGTTGGAACTATGACGACAAC
GGTGGCGGTAGAATCGCAGGAAGTTGACCCTTCTAGACTGTCGCGTTACAAAGCGAACGAACCATGGGCACTTGTTGGCC
CTGAAGTGAAAAACCCTGAGTATCGAACTGAGGATTTCCGCGATCCGCGTACTGCGGTAACGGAGGCTCGCAGTACAGTT
AACGGGGTCGGTGTGTCTGCAATCTTTCATAAGGAAGATAAGACCATCGAAGGTGTATCGTTTTTGACCAACGGTGCTGA
TCAGTCAGAGTACCGAGCCACGAGTGAAATGCTTGCCGGCAGTCCCTCACCGGCAAGCCTACCTGCATTGGGTATTTTTA
CGGCACAATCTGGGCATACTAAAAAGATCAACGACAAGGAAATGCTCGACTATAAAGGTCGTATTCCTGTTGGTACCCTG
ACGCTTAAGTTTGACCAGCCTGTTAAAGATCCAATTCTTGATTTTTCGGGTTTGGGCGGTTATAACATCTTTTCGGCGCA
TCATGAAGAGGCCTCGCACGAAGGCATTCGAAATTGGGAAGTTCGAAATGGCAAAATCGTTGTGACGGGCGAATCTGCCT
CTGTTGTGGGTGCCCAGATTAATGATCAAATTCGTGGATCTTTCAACCACACTGATTTGGAATTGGAAACGCCTGGTGTC
AAATTAGTCGAGCTGGCCAAAAACTCGAATCTAAAGGTGGATGACCGGAGTATTTCCACTGTAGCTGCTAATAACGATTA
TGTATGTAATACTCCCAACGATTACCAAACTTTACCTGAGGAATTGGAAAACGGGCCAAGCTATGAGCAAAATGACGCCT
TTCTTTCTCCAGTGATGAAACCGGCTGGATGTGGTTCTGTTCTAGCTCAAGGTGAGTTTTCAGAACTGAAATTTACACTT
TTTTCATCAGTTGAGCCCATGTCAAGTTTTGCTCATGATACGCATAAGACTGGCCTGTTGTATTTTGCTGGTGGTGTAAA
CGGGGGTAATGCTAATCCCGTGACACCAATCCCAATGCTTGAGGGATATTCGAAGCCGCAGGAAGTCTCTGATACTAGCA
ATGGCGATTTGTTCCGAATGAGTATTCGACTGCCGGAAGAGCCGGTTAAGGGTTCTGTGTCTGTTGGTGACTTTGTCTGG
ATTGATAAAGACGCTGATGGTAGGCAGGATGACAATGAGCCGGGTCTTGCTGGTGTTAAGTTGTGGCTTTATGGCCCTGA
TGGTGGTCCGGTTACGGATGTTCATGGCAAAGTTGTGAAGTCTGTAACTACTGGTGAGGATGGTAAGTATTCGTTTAAGG
ATCTTCCGGTTCTTACGGGTAGTGATTCTTACACCGTGAAGGTTGTGGATGTTCCTGCTGGTTACAAACCAACGTTGTCT
GGTACTGGTAAGGTTCCTGCGTTTAAGGATTCTTCTACTGATTTGGCTAAGTCGACGCCTGGTGCGTTGAGTGAAAATGG
TGCGCAGGATCTGACTCTTGATTTTGGTTTTGTTAAGGAGTCGGCTACGCCTAGCGACCCAACCGTTCCTGGTTTTAAAT
GGTGGATTCCGTTGATTCCATTGGCATTGGTACCTTTGATACCAATGCTCGCTCAAACAGTTGGCGGATCTTCGGCTCCA
GCAACGAGCGCTCCACAGGTACCAAACGCTCCTGTTTCTACTTCAAATGATCCAAAGCCGGCTCCTGTGGCACAGAAGCC
TCAAAATAAGCAGCTTGCTGCGACTGGTGCAAGTGTTCTTGGATTGTTGGCGATGGCGTTAGCTTTGATTGCGGGTGGCG
TATTGCTTCTTCGATCAAGGAAAGAAAGCTAA

Upstream 100 bases:

>100_bases
GTCTGACTGCATTGGAATTAAAAGAACTGTATATATCTCGAAGTTATAGAAGTTCTGATATTATGATTTTCTCAACTCAA
TTTTTGGAAGATGTGAGATT

Downstream 100 bases:

>100_bases
GCCAGCTAGATAATCTGGAGATTCGTAGCAGCGCATTTCTAGTGAATGTATGGGCTTGCTACAAGTTGAACAGATGAATT
TGCACTTATACAGTGCGTTA

Product: putative surface anchored protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MALNFRRRSRVLAILTSLSVVGTMTTTVAVESQEVDPSRLSRYKANEPWALVGPEVKNPEYRTEDFRDPRTAVTEARSTV
NGVGVSAIFHKEDKTIEGVSFLTNGADQSEYRATSEMLAGSPSPASLPALGIFTAQSGHTKKINDKEMLDYKGRIPVGTL
TLKFDQPVKDPILDFSGLGGYNIFSAHHEEASHEGIRNWEVRNGKIVVTGESASVVGAQINDQIRGSFNHTDLELETPGV
KLVELAKNSNLKVDDRSISTVAANNDYVCNTPNDYQTLPEELENGPSYEQNDAFLSPVMKPAGCGSVLAQGEFSELKFTL
FSSVEPMSSFAHDTHKTGLLYFAGGVNGGNANPVTPIPMLEGYSKPQEVSDTSNGDLFRMSIRLPEEPVKGSVSVGDFVW
IDKDADGRQDDNEPGLAGVKLWLYGPDGGPVTDVHGKVVKSVTTGEDGKYSFKDLPVLTGSDSYTVKVVDVPAGYKPTLS
GTGKVPAFKDSSTDLAKSTPGALSENGAQDLTLDFGFVKESATPSDPTVPGFKWWIPLIPLALVPLIPMLAQTVGGSSAP
ATSAPQVPNAPVSTSNDPKPAPVAQKPQNKQLAATGASVLGLLAMALALIAGGVLLLRSRKES

Sequences:

>Translated_623_residues
MALNFRRRSRVLAILTSLSVVGTMTTTVAVESQEVDPSRLSRYKANEPWALVGPEVKNPEYRTEDFRDPRTAVTEARSTV
NGVGVSAIFHKEDKTIEGVSFLTNGADQSEYRATSEMLAGSPSPASLPALGIFTAQSGHTKKINDKEMLDYKGRIPVGTL
TLKFDQPVKDPILDFSGLGGYNIFSAHHEEASHEGIRNWEVRNGKIVVTGESASVVGAQINDQIRGSFNHTDLELETPGV
KLVELAKNSNLKVDDRSISTVAANNDYVCNTPNDYQTLPEELENGPSYEQNDAFLSPVMKPAGCGSVLAQGEFSELKFTL
FSSVEPMSSFAHDTHKTGLLYFAGGVNGGNANPVTPIPMLEGYSKPQEVSDTSNGDLFRMSIRLPEEPVKGSVSVGDFVW
IDKDADGRQDDNEPGLAGVKLWLYGPDGGPVTDVHGKVVKSVTTGEDGKYSFKDLPVLTGSDSYTVKVVDVPAGYKPTLS
GTGKVPAFKDSSTDLAKSTPGALSENGAQDLTLDFGFVKESATPSDPTVPGFKWWIPLIPLALVPLIPMLAQTVGGSSAP
ATSAPQVPNAPVSTSNDPKPAPVAQKPQNKQLAATGASVLGLLAMALALIAGGVLLLRSRKES
>Mature_622_residues
ALNFRRRSRVLAILTSLSVVGTMTTTVAVESQEVDPSRLSRYKANEPWALVGPEVKNPEYRTEDFRDPRTAVTEARSTVN
GVGVSAIFHKEDKTIEGVSFLTNGADQSEYRATSEMLAGSPSPASLPALGIFTAQSGHTKKINDKEMLDYKGRIPVGTLT
LKFDQPVKDPILDFSGLGGYNIFSAHHEEASHEGIRNWEVRNGKIVVTGESASVVGAQINDQIRGSFNHTDLELETPGVK
LVELAKNSNLKVDDRSISTVAANNDYVCNTPNDYQTLPEELENGPSYEQNDAFLSPVMKPAGCGSVLAQGEFSELKFTLF
SSVEPMSSFAHDTHKTGLLYFAGGVNGGNANPVTPIPMLEGYSKPQEVSDTSNGDLFRMSIRLPEEPVKGSVSVGDFVWI
DKDADGRQDDNEPGLAGVKLWLYGPDGGPVTDVHGKVVKSVTTGEDGKYSFKDLPVLTGSDSYTVKVVDVPAGYKPTLSG
TGKVPAFKDSSTDLAKSTPGALSENGAQDLTLDFGFVKESATPSDPTVPGFKWWIPLIPLALVPLIPMLAQTVGGSSAPA
TSAPQVPNAPVSTSNDPKPAPVAQKPQNKQLAATGASVLGLLAMALALIAGGVLLLRSRKES

Specific function: Cell surface-associated protein causing human platelet aggregation. Appears to be involved in the aggregation of host platelets thus playing a role in infective endocarditis. May bind calcium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 CNA-B domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011266
- InterPro:   IPR008966
- InterPro:   IPR008454
- InterPro:   IPR008970
- InterPro:   IPR011252
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR013783
- InterPro:   IPR019931
- InterPro:   IPR001899 [H]

Pfam domain/function: PF05738 Cna_B; PF00746 Gram_pos_anchor; PF10425 SdrG_C_C; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 66362; Mature: 66231

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNFRRRSRVLAILTSLSVVGTMTTTVAVESQEVDPSRLSRYKANEPWALVGPEVKNPE
CCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHCCCCCCEEEECCCCCCCC
YRTEDFRDPRTAVTEARSTVNGVGVSAIFHKEDKTIEGVSFLTNGADQSEYRATSEMLAG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHCC
SPSPASLPALGIFTAQSGHTKKINDKEMLDYKGRIPVGTLTLKFDQPVKDPILDFSGLGG
CCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
YNIFSAHHEEASHEGIRNWEVRNGKIVVTGESASVVGAQINDQIRGSFNHTDLELETPGV
CCEEHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEECCHHHCCCCCCCEEEEECCCC
KLVELAKNSNLKVDDRSISTVAANNDYVCNTPNDYQTLPEELENGPSYEQNDAFLSPVMK
EEEEEECCCCCEECCCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHCCC
PAGCGSVLAQGEFSELKFTLFSSVEPMSSFAHDTHKTGLLYFAGGVNGGNANPVTPIPML
CCCCCHHHCCCCHHHEEEEEHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHH
EGYSKPQEVSDTSNGDLFRMSIRLPEEPVKGSVSVGDFVWIDKDADGRQDDNEPGLAGVK
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEECEEEEEECCCCCCCCCCCCCCEEEE
LWLYGPDGGPVTDVHGKVVKSVTTGEDGKYSFKDLPVLTGSDSYTVKVVDVPAGYKPTLS
EEEECCCCCCCCCCCHHHHHHEECCCCCCEECCCCCEEECCCCEEEEEEECCCCCCCCCC
GTGKVPAFKDSSTDLAKSTPGALSENGAQDLTLDFGFVKESATPSDPTVPGFKWWIPLIP
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LALVPLIPMLAQTVGGSSAPATSAPQVPNAPVSTSNDPKPAPVAQKPQNKQLAATGASVL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
GLLAMALALIAGGVLLLRSRKES
HHHHHHHHHHHCCEEEEECCCCC
>Mature Secondary Structure 
ALNFRRRSRVLAILTSLSVVGTMTTTVAVESQEVDPSRLSRYKANEPWALVGPEVKNPE
CCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHCCCCCCEEEECCCCCCCC
YRTEDFRDPRTAVTEARSTVNGVGVSAIFHKEDKTIEGVSFLTNGADQSEYRATSEMLAG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHCC
SPSPASLPALGIFTAQSGHTKKINDKEMLDYKGRIPVGTLTLKFDQPVKDPILDFSGLGG
CCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
YNIFSAHHEEASHEGIRNWEVRNGKIVVTGESASVVGAQINDQIRGSFNHTDLELETPGV
CCEEHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEECCHHHCCCCCCCEEEEECCCC
KLVELAKNSNLKVDDRSISTVAANNDYVCNTPNDYQTLPEELENGPSYEQNDAFLSPVMK
EEEEEECCCCCEECCCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHCCC
PAGCGSVLAQGEFSELKFTLFSSVEPMSSFAHDTHKTGLLYFAGGVNGGNANPVTPIPML
CCCCCHHHCCCCHHHEEEEEHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHH
EGYSKPQEVSDTSNGDLFRMSIRLPEEPVKGSVSVGDFVWIDKDADGRQDDNEPGLAGVK
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEECEEEEEECCCCCCCCCCCCCCEEEE
LWLYGPDGGPVTDVHGKVVKSVTTGEDGKYSFKDLPVLTGSDSYTVKVVDVPAGYKPTLS
EEEECCCCCCCCCCCHHHHHHEECCCCCCEECCCCCEEECCCCEEEEEEECCCCCCCCCC
GTGKVPAFKDSSTDLAKSTPGALSENGAQDLTLDFGFVKESATPSDPTVPGFKWWIPLIP
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LALVPLIPMLAQTVGGSSAPATSAPQVPNAPVSTSNDPKPAPVAQKPQNKQLAATGASVL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
GLLAMALALIAGGVLLLRSRKES
HHHHHHHHHHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA