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The map label for this gene is fprA [H]

Identifier: 38234613

GI number: 38234613

Start: 2105308

End: 2106666

Strand: Direct

Name: fprA [H]

Synonym: DIP2056

Alternate gene names: 38234613

Gene position: 2105308-2106666 (Clockwise)

Preceding gene: 38234610

Following gene: 38234615

Centisome position: 84.6

GC content: 59.82

Gene sequence:

>1359_bases
ATGACTGAACCTTTGCGCGTCGCCGTCATCGGCTCCGGCCCCGCAGGCATCTACGCCTCCGACCTCCTCACCAAAAACAA
CCCCACCACCACCGTCGACCTCTACGAACGCATGCCCGCCCCCTTCGGGCTCATCCGCTACGGCGTAGCACCCGACCACC
CACGCATCAAAGGCATTATCACCTCCCTCCACAAAGTCCTCAGCAACCCCAACATCCGCCTTATCGGCAACGTCACCATC
GGCACCGACCTCACTATCGACGACCTCCGCCACCACTACGACGCCATCATCCTCGCCACCGGGGCCACCGCAGACCGCAA
CCTCACCATCCCAGGCGCAGAACTCGAAGGCTCCCACGGCGCAGCAGAATTCGTCGGCTTCTACGACGGCAACCCCGACT
TCCAACGCACCTGGGACCTCACCGCCACCGACGTCGCCGTCATCGGCGTCGGAAACGTAGGCCTCGACGTCGCCCGCATC
CTCGCCAAAACCGCCGACGAACTCCACACCACCGAAATCCCCGACAACGTCTACCACACCCTCAAAAACAACCAAGCCAC
CACCATCCACGTCTTCGGCCGACGCGGACCAGCACAAGTCAAATTCAGCCCCCTCGAACTCAAAGAACTCGACCACTCCC
CCACCATCGAGGTCATCGTCGACCCCGAAGACATCGACTACGACGACACCTCCATCACCACACGACGCCAATCCAAATCC
CAAGACCTCGTGTGTCAAACACTCGAAAACTACGCCATGCGCGAACCGAAAGGAGCACCCCACAAACTCCACATCCACCT
GTTCGAATCCCCCGTAGAAATCCTAGGCACCAACGGACACGTCACCGCACTACGCACCGAACGCACCGAATACGACGGCA
ACGGAGGAATCCGCGGCACCGGCAAATACACCGACTGGCCCATCCAAGCCGTCTACCGCGCAGTCGGCTACCGCTCCGAA
CCCATCAACGACGTCCCCTTCGACACCACCAACCACGTCATCTACAACGACGGTGGACACGTCACCACACAAGATGGCAC
CATCATCCCAGGGCTCTACACCACCGGATGGATCAAACGCGGACCCGTAGGCCTTATCGGCAACACCAAATCCGACGCTA
AAGAAACCACCGAAATGCTCATCAACGACTGGGAAACAGGACAACTCACCCCAGCCGACAACCGCGACCCAAATGCCATC
TTCGACGTGTTAAAACAACGCGGCATCCCCGTGACCACTTGGGACGGATGGCACGCACTCGACGCAGCAGAACGCGAACT
CGGGCAGGCAGAAGGACGCGAACGCAAAAAAATCGTCGAATGGAACGACATGCTCCAGCACGCCGCCAAAAAGGACTAA

Upstream 100 bases:

>100_bases
CTTGCGCGTAAACTAGTACGCCGAAACTCAATTAACCCATGTGAACGGGTTAAATTCAGAACATTTACACCTGACCTCTA
TCACTAGGAATGTGACATTT

Downstream 100 bases:

>100_bases
CCCATGAAACGCTAACCCCTCAGCTCAGATACCGCTGCGCGAGCCGACTCCCGCGCCTGCTCAGCGGTATCAGCCGTAGC
AAGAGTCACCGCCAATGTCT

Product: putative ferredoxin/ferredoxin-NADP reductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTEPLRVAVIGSGPAGIYASDLLTKNNPTTTVDLYERMPAPFGLIRYGVAPDHPRIKGIITSLHKVLSNPNIRLIGNVTI
GTDLTIDDLRHHYDAIILATGATADRNLTIPGAELEGSHGAAEFVGFYDGNPDFQRTWDLTATDVAVIGVGNVGLDVARI
LAKTADELHTTEIPDNVYHTLKNNQATTIHVFGRRGPAQVKFSPLELKELDHSPTIEVIVDPEDIDYDDTSITTRRQSKS
QDLVCQTLENYAMREPKGAPHKLHIHLFESPVEILGTNGHVTALRTERTEYDGNGGIRGTGKYTDWPIQAVYRAVGYRSE
PINDVPFDTTNHVIYNDGGHVTTQDGTIIPGLYTTGWIKRGPVGLIGNTKSDAKETTEMLINDWETGQLTPADNRDPNAI
FDVLKQRGIPVTTWDGWHALDAAERELGQAEGRERKKIVEWNDMLQHAAKKD

Sequences:

>Translated_452_residues
MTEPLRVAVIGSGPAGIYASDLLTKNNPTTTVDLYERMPAPFGLIRYGVAPDHPRIKGIITSLHKVLSNPNIRLIGNVTI
GTDLTIDDLRHHYDAIILATGATADRNLTIPGAELEGSHGAAEFVGFYDGNPDFQRTWDLTATDVAVIGVGNVGLDVARI
LAKTADELHTTEIPDNVYHTLKNNQATTIHVFGRRGPAQVKFSPLELKELDHSPTIEVIVDPEDIDYDDTSITTRRQSKS
QDLVCQTLENYAMREPKGAPHKLHIHLFESPVEILGTNGHVTALRTERTEYDGNGGIRGTGKYTDWPIQAVYRAVGYRSE
PINDVPFDTTNHVIYNDGGHVTTQDGTIIPGLYTTGWIKRGPVGLIGNTKSDAKETTEMLINDWETGQLTPADNRDPNAI
FDVLKQRGIPVTTWDGWHALDAAERELGQAEGRERKKIVEWNDMLQHAAKKD
>Mature_451_residues
TEPLRVAVIGSGPAGIYASDLLTKNNPTTTVDLYERMPAPFGLIRYGVAPDHPRIKGIITSLHKVLSNPNIRLIGNVTIG
TDLTIDDLRHHYDAIILATGATADRNLTIPGAELEGSHGAAEFVGFYDGNPDFQRTWDLTATDVAVIGVGNVGLDVARIL
AKTADELHTTEIPDNVYHTLKNNQATTIHVFGRRGPAQVKFSPLELKELDHSPTIEVIVDPEDIDYDDTSITTRRQSKSQ
DLVCQTLENYAMREPKGAPHKLHIHLFESPVEILGTNGHVTALRTERTEYDGNGGIRGTGKYTDWPIQAVYRAVGYRSEP
INDVPFDTTNHVIYNDGGHVTTQDGTIIPGLYTTGWIKRGPVGLIGNTKSDAKETTEMLINDWETGQLTPADNRDPNAIF
DVLKQRGIPVTTWDGWHALDAAERELGQAEGRERKKIVEWNDMLQHAAKKD

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=456, Percent_Identity=35.3070175438597, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI111118983, Length=462, Percent_Identity=35.2813852813853, Blast_Score=261, Evalue=9e-70,
Organism=Escherichia coli, GI1788811, Length=163, Percent_Identity=30.0613496932515, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789606, Length=162, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082180, Length=160, Percent_Identity=27.5, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=457, Percent_Identity=29.7592997811816, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17570289, Length=120, Percent_Identity=35.8333333333333, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320584, Length=481, Percent_Identity=28.4823284823285, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320030, Length=119, Percent_Identity=36.1344537815126, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17137178, Length=462, Percent_Identity=31.8181818181818, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24665547, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24665543, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28574881, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24665539, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 49813; Mature: 49682

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPLRVAVIGSGPAGIYASDLLTKNNPTTTVDLYERMPAPFGLIRYGVAPDHPRIKGII
CCCCEEEEEEECCCCCCCHHHHEECCCCCEEEEHHHHCCCCHHHEEECCCCCCCHHHHHH
TSLHKVLSNPNIRLIGNVTIGTDLTIDDLRHHYDAIILATGATADRNLTIPGAELEGSHG
HHHHHHHCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCC
AAEFVGFYDGNPDFQRTWDLTATDVAVIGVGNVGLDVARILAKTADELHTTEIPDNVYHT
CEEEEEEECCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
LKNNQATTIHVFGRRGPAQVKFSPLELKELDHSPTIEVIVDPEDIDYDDTSITTRRQSKS
HCCCCEEEEEEEECCCCCEEEECCCHHHHCCCCCCEEEEECCCCCCCCCCCCEEHHCCCC
QDLVCQTLENYAMREPKGAPHKLHIHLFESPVEILGTNGHVTALRTERTEYDGNGGIRGT
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHEECCCCCEEEEEECCCCCCCCCCEECC
GKYTDWPIQAVYRAVGYRSEPINDVPFDTTNHVIYNDGGHVTTQDGTIIPGLYTTGWIKR
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEECCCEECCCCCCCCCCCC
GPVGLIGNTKSDAKETTEMLINDWETGQLTPADNRDPNAIFDVLKQRGIPVTTWDGWHAL
CCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCHHH
DAAERELGQAEGRERKKIVEWNDMLQHAAKKD
HHHHHHHHHHCCHHHHHEECHHHHHHHHHCCC
>Mature Secondary Structure 
TEPLRVAVIGSGPAGIYASDLLTKNNPTTTVDLYERMPAPFGLIRYGVAPDHPRIKGII
CCCEEEEEEECCCCCCCHHHHEECCCCCEEEEHHHHCCCCHHHEEECCCCCCCHHHHHH
TSLHKVLSNPNIRLIGNVTIGTDLTIDDLRHHYDAIILATGATADRNLTIPGAELEGSHG
HHHHHHHCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCC
AAEFVGFYDGNPDFQRTWDLTATDVAVIGVGNVGLDVARILAKTADELHTTEIPDNVYHT
CEEEEEEECCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
LKNNQATTIHVFGRRGPAQVKFSPLELKELDHSPTIEVIVDPEDIDYDDTSITTRRQSKS
HCCCCEEEEEEEECCCCCEEEECCCHHHHCCCCCCEEEEECCCCCCCCCCCCEEHHCCCC
QDLVCQTLENYAMREPKGAPHKLHIHLFESPVEILGTNGHVTALRTERTEYDGNGGIRGT
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHEECCCCCEEEEEECCCCCCCCCCEECC
GKYTDWPIQAVYRAVGYRSEPINDVPFDTTNHVIYNDGGHVTTQDGTIIPGLYTTGWIKR
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEECCCEECCCCCCCCCCCC
GPVGLIGNTKSDAKETTEMLINDWETGQLTPADNRDPNAIFDVLKQRGIPVTTWDGWHAL
CCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCHHH
DAAERELGQAEGRERKKIVEWNDMLQHAAKKD
HHHHHHHHHHCCHHHHHEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]