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The map label for this gene is pfpI [H]

Identifier: 38234592

GI number: 38234592

Start: 2084696

End: 2085232

Strand: Direct

Name: pfpI [H]

Synonym: DIP2032

Alternate gene names: 38234592

Gene position: 2084696-2085232 (Clockwise)

Preceding gene: 38234591

Following gene: 38234594

Centisome position: 83.77

GC content: 51.77

Gene sequence:

>537_bases
ATGTCTGACCTCAGCAATAAAAAAGTTCTTATTCTCGCTAGTCAGGGTGTAGAGCAGATTGAGCTCACCTCACCTCGTGA
TGCGCTCAAGGATGCCGGCGTGCAGGTTTCATTGGCAGCACCCGAGGGCAAGGAATTCCAGGGTATGAACGGCGACTGGG
AGAAGGCAGATACCTTTACCCCTGACTTGGCATTGGCAGATGTCAACGTTGAAGAATTCGATGCGCTTGTCCTTGCCGGC
GGTACCCTCAACGCTGATGCCATGCGTATCAACCCCGAGGCTCGCTCCATTACTGTTCAGTTCTTTGAGGCAGAAAAGCC
CGTTGCAGCAATCTGCCATGCACCTTGGTTGCTCATTGATTCCAAGAAGGTTGAGGGCAAGAAACTCACCTCCTACACGT
CGGTAAAGTCTGATCTCGAAAACGCTGGTGCTATATGGGTTGATGAGGAAGTCGTGGAAGACGGCAATCTCATCACCAGC
CGTAACCCCGGTGACCTTGAGGCTTTCAACAAGGCAATCATCGCTAAGTTGAGCTAG

Upstream 100 bases:

>100_bases
GCTCGATCCTGTAAATTTGAAAGAATTTTGTAAATCTTCCTCTGTCCACTACGGTCAGAATAGTAAGTTTTCTTACTATC
ACTAGATTCAAGGGGTACTC

Downstream 100 bases:

>100_bases
TCCCACTTAGGCAGATATAAGCCTTCATCACACGATACGCAGGTAGGCAAATTCTCGGTTAGCTTTGCCGGGATTTACTC
TACCTGCGTATTAGTTTTGG

Product: putative protease

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSDLSNKKVLILASQGVEQIELTSPRDALKDAGVQVSLAAPEGKEFQGMNGDWEKADTFTPDLALADVNVEEFDALVLAG
GTLNADAMRINPEARSITVQFFEAEKPVAAICHAPWLLIDSKKVEGKKLTSYTSVKSDLENAGAIWVDEEVVEDGNLITS
RNPGDLEAFNKAIIAKLS

Sequences:

>Translated_178_residues
MSDLSNKKVLILASQGVEQIELTSPRDALKDAGVQVSLAAPEGKEFQGMNGDWEKADTFTPDLALADVNVEEFDALVLAG
GTLNADAMRINPEARSITVQFFEAEKPVAAICHAPWLLIDSKKVEGKKLTSYTSVKSDLENAGAIWVDEEVVEDGNLITS
RNPGDLEAFNKAIIAKLS
>Mature_177_residues
SDLSNKKVLILASQGVEQIELTSPRDALKDAGVQVSLAAPEGKEFQGMNGDWEKADTFTPDLALADVNVEEFDALVLAGG
TLNADAMRINPEARSITVQFFEAEKPVAAICHAPWLLIDSKKVEGKKLTSYTSVKSDLENAGAIWVDEEVVEDGNLITSR
NPGDLEAFNKAIIAKLS

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=177, Percent_Identity=29.9435028248588, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI31543380, Length=177, Percent_Identity=29.9435028248588, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI87082219, Length=168, Percent_Identity=39.2857142857143, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17531319, Length=166, Percent_Identity=31.3253012048193, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571932, Length=168, Percent_Identity=35.1190476190476, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653499, Length=177, Percent_Identity=30.5084745762712, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19174; Mature: 19043

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSNKKVLILASQGVEQIELTSPRDALKDAGVQVSLAAPEGKEFQGMNGDWEKADTFT
CCCCCCCEEEEEECCCCCEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PDLALADVNVEEFDALVLAGGTLNADAMRINPEARSITVQFFEAEKPVAAICHAPWLLID
CCEEEEECCHHHCCEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCEEHHCCCEEEEE
SKKVEGKKLTSYTSVKSDLENAGAIWVDEEVVEDGNLITSRNPGDLEAFNKAIIAKLS
CCCCCCCEEHHHHHHHHHHHHCCEEEECHHHHCCCCEEECCCCCCHHHHCCEEEEECC
>Mature Secondary Structure 
SDLSNKKVLILASQGVEQIELTSPRDALKDAGVQVSLAAPEGKEFQGMNGDWEKADTFT
CCCCCCEEEEEECCCCCEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PDLALADVNVEEFDALVLAGGTLNADAMRINPEARSITVQFFEAEKPVAAICHAPWLLID
CCEEEEECCHHHCCEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCEEHHCCCEEEEE
SKKVEGKKLTSYTSVKSDLENAGAIWVDEEVVEDGNLITSRNPGDLEAFNKAIIAKLS
CCCCCCCEEHHHHHHHHHHHHCCEEEECHHHHCCCCEEECCCCCCHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA