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The map label for this gene is moaB [H]

Identifier: 158336951

GI number: 158336951

Start: 3870925

End: 3871437

Strand: Direct

Name: moaB [H]

Synonym: AM1_3822

Alternate gene names: 158336951

Gene position: 3870925-3871437 (Clockwise)

Preceding gene: 158336949

Following gene: 158336952

Centisome position: 59.52

GC content: 51.07

Gene sequence:

>513_bases
ATGGCAAAGCAGTTTATTCCCATTAATATTGCGGTGATGACGGTGTCTGATACGCGTACGGAAGACACGGATACCTCCGG
GAAACTGTTGTGCGATCGCATCCAGGAAACCGGACATACTCTAGCTGAAAAAGTCATCGTTCCTGACGACATCTACCAAA
TTCGTGCGGTTGTTTCTCGCTGGATCGCCGATGAATCCGTACAGGCCATTATCACTACCGGAGGCACGGGGGTAACGGGA
CGGGACGGCACGCCAGAAGCGATCAAACCCTTGCTGGATAAGGAAATCCAGGGGTTTGGCGAAATCTTCCGCATGATCTC
CTACGAAGACATTAAGACTTCAACAATTCAGTCTCGGGCCTTATCGGGAGTCGCCAATGGCACCTACCTGTTTTGTCTAC
CCGGTTCATCTGGTGCTTGTCGTACAGGTTGGGATGCGCTGATTCATGACCAATTGGATGTTCGCCATTCTCCCTGTAAT
CTGGCAGAGCTTATGCCTCGATTGCGGGAATAG

Upstream 100 bases:

>100_bases
TGGAACCTTAGCATGAGTAAAGCGTGATTTCAGAAAATAATAAATGTCTGGAGTTTCACTACCCTAGTTCAGTCAGATAG
AAACGAGTGGGAGCATCAGG

Downstream 100 bases:

>100_bases
GCTGTCGGTGTTTTTTACCTCAATCTAACAGGCTAGCTTGGTACGCTAGGCTTTAGCCCGTCGCACCTATTTCGACAACC
TATGAAAAAACTCCACCTCG

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MAKQFIPINIAVMTVSDTRTEDTDTSGKLLCDRIQETGHTLAEKVIVPDDIYQIRAVVSRWIADESVQAIITTGGTGVTG
RDGTPEAIKPLLDKEIQGFGEIFRMISYEDIKTSTIQSRALSGVANGTYLFCLPGSSGACRTGWDALIHDQLDVRHSPCN
LAELMPRLRE

Sequences:

>Translated_170_residues
MAKQFIPINIAVMTVSDTRTEDTDTSGKLLCDRIQETGHTLAEKVIVPDDIYQIRAVVSRWIADESVQAIITTGGTGVTG
RDGTPEAIKPLLDKEIQGFGEIFRMISYEDIKTSTIQSRALSGVANGTYLFCLPGSSGACRTGWDALIHDQLDVRHSPCN
LAELMPRLRE
>Mature_169_residues
AKQFIPINIAVMTVSDTRTEDTDTSGKLLCDRIQETGHTLAEKVIVPDDIYQIRAVVSRWIADESVQAIITTGGTGVTGR
DGTPEAIKPLLDKEIQGFGEIFRMISYEDIKTSTIQSRALSGVANGTYLFCLPGSSGACRTGWDALIHDQLDVRHSPCNL
AELMPRLRE

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:
GO:0006777: Molybdenum cofactor biosynthesis protein B

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=134, Percent_Identity=35.8208955223881, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI10880983, Length=134, Percent_Identity=35.8208955223881, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787000, Length=170, Percent_Identity=52.3529411764706, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17564954, Length=148, Percent_Identity=33.7837837837838, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136978, Length=145, Percent_Identity=37.9310344827586, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=145, Percent_Identity=37.9310344827586, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18624; Mature: 18493

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQFIPINIAVMTVSDTRTEDTDTSGKLLCDRIQETGHTLAEKVIVPDDIYQIRAVVSR
CCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WIADESVQAIITTGGTGVTGRDGTPEAIKPLLDKEIQGFGEIFRMISYEDIKTSTIQSRA
HHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVANGTYLFCLPGSSGACRTGWDALIHDQLDVRHSPCNLAELMPRLRE
HHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AKQFIPINIAVMTVSDTRTEDTDTSGKLLCDRIQETGHTLAEKVIVPDDIYQIRAVVSR
CCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WIADESVQAIITTGGTGVTGRDGTPEAIKPLLDKEIQGFGEIFRMISYEDIKTSTIQSRA
HHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVANGTYLFCLPGSSGACRTGWDALIHDQLDVRHSPCNLAELMPRLRE
HHHCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]