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The map label for this gene is fbp

Identifier: 158336016

GI number: 158336016

Start: 2914255

End: 2915328

Strand: Direct

Name: fbp

Synonym: AM1_2875

Alternate gene names: 158336016

Gene position: 2914255-2915328 (Clockwise)

Preceding gene: 158336015

Following gene: 158336017

Centisome position: 44.81

GC content: 49.35

Gene sequence:

>1074_bases
ATGAATAGTTCTGACAGCACTTCCCTTGAACTAAGTTACGATTTTGCGCTTGACCGGGACTGCACGACCTTGTCTCGTCA
TGTTCTAGAACATCTCCAAAGTTTTAGCCCAGAAGCCCAAGATATGAGTGCTCTGATGACTCGAATTGGGTTGGCCGGGA
AACTGATTGCTCGCCGCCTCAGTCGAGCGGGGCTTGTAGAAGGCGCTTTAGGCTTCACAGGCGATATCAATGTCCAGGGC
GAAGAAGTCAAAAAAATGGACATCTATGCCAATGAGGTGTTTATTGCCGCCTTTAAGCAGAGTGGTCTGGTATGTCGGCT
CGCCTCTGAAGAAATGGAGAAGCCTTACTACATCCCTGAAAACTGCCCCATTGGTCGGTATACCCTGCTATATGACCCCA
TTGATGGGTCTTCCAACGTGGATGTGAACTTGAACGTTGGCTCTATTTTTTCCATTCGCCAGCAAGTCGGTAACGATCCC
GACCATACAGGTCAGGATCTCTTACAAGATGGCCATCAGCAAATTGCCGCAGGCTATATTCTGTACGGTCCCAGTACCGT
CTTGGTGTATTCCATTGGCAAAGGGGTCCATGTTTTTATCCTTGATCCAAGCCTGGGAGAATTTATTCTGGCTGCTGAAA
ACCTGACGATCCCTAAACATGGTCCAGTCTATAGCGTCAATGAGGGGAATTTCTGGCAATGGGAAGATGCCCTCCGGGAC
TTTACTCGCTATGTTCATCGCCATGAAGGCCATACGGCCCGCTACAGCGGGGCTTTGGTGGGAGATTTTCATCGCATCTT
ATTTCAAGGGGGTGTGTTTATCTACCCCGGCACCCTGAAAAATCCTGATGGTAAGCTGCGACTGCTCTATGAATCGGCCC
CCTTAGCCTATTTGATGGAGCAAGCGGGCGGACGAGCCAGTATAGGCCAATCTCCTTTAATGGACGTGGTTCCCGATCAT
CTTCATGCCCGTACGCCTTTGATTATTGGCAGCACTGAGGATGTGGCCTTAGTTGAATCTTTTATTGAAGACAGAGAAAG
ACAGGCGGAAGAAGAGCTTGCGCTGAAGTCCTAA

Upstream 100 bases:

>100_bases
AAAGACTCAGGCCATTTTCAGAATGCCTTCTTAAGATGGGAGGTATCAAGACAGAGCCACCCGCAACAGGGCCGTCTGTC
ACCCATTATGGGGACCTCAA

Downstream 100 bases:

>100_bases
CGGCAGAACCTACCCTTATTACTCGATCGATTACGGAGTTTCCTATGACAAACCATCTCCTCGAAATCAGCACCTTTGGT
CAAAGCATTTGGATGGACAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNSSDSTSLELSYDFALDRDCTTLSRHVLEHLQSFSPEAQDMSALMTRIGLAGKLIARRLSRAGLVEGALGFTGDINVQG
EEVKKMDIYANEVFIAAFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPIDGSSNVDVNLNVGSIFSIRQQVGNDP
DHTGQDLLQDGHQQIAAGYILYGPSTVLVYSIGKGVHVFILDPSLGEFILAAENLTIPKHGPVYSVNEGNFWQWEDALRD
FTRYVHRHEGHTARYSGALVGDFHRILFQGGVFIYPGTLKNPDGKLRLLYESAPLAYLMEQAGGRASIGQSPLMDVVPDH
LHARTPLIIGSTEDVALVESFIEDRERQAEEELALKS

Sequences:

>Translated_357_residues
MNSSDSTSLELSYDFALDRDCTTLSRHVLEHLQSFSPEAQDMSALMTRIGLAGKLIARRLSRAGLVEGALGFTGDINVQG
EEVKKMDIYANEVFIAAFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPIDGSSNVDVNLNVGSIFSIRQQVGNDP
DHTGQDLLQDGHQQIAAGYILYGPSTVLVYSIGKGVHVFILDPSLGEFILAAENLTIPKHGPVYSVNEGNFWQWEDALRD
FTRYVHRHEGHTARYSGALVGDFHRILFQGGVFIYPGTLKNPDGKLRLLYESAPLAYLMEQAGGRASIGQSPLMDVVPDH
LHARTPLIIGSTEDVALVESFIEDRERQAEEELALKS
>Mature_357_residues
MNSSDSTSLELSYDFALDRDCTTLSRHVLEHLQSFSPEAQDMSALMTRIGLAGKLIARRLSRAGLVEGALGFTGDINVQG
EEVKKMDIYANEVFIAAFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPIDGSSNVDVNLNVGSIFSIRQQVGNDP
DHTGQDLLQDGHQQIAAGYILYGPSTVLVYSIGKGVHVFILDPSLGEFILAAENLTIPKHGPVYSVNEGNFWQWEDALRD
FTRYVHRHEGHTARYSGALVGDFHRILFQGGVFIYPGTLKNPDGKLRLLYESAPLAYLMEQAGGRASIGQSPLMDVVPDH
LHARTPLIIGSTEDVALVESFIEDRERQAEEELALKS

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=41.1042944785276, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI189083692, Length=327, Percent_Identity=40.3669724770642, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI16579888, Length=327, Percent_Identity=40.3669724770642, Blast_Score=236, Evalue=2e-62,
Organism=Escherichia coli, GI1790679, Length=328, Percent_Identity=44.2073170731707, Blast_Score=287, Evalue=8e-79,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=42.1538461538462, Blast_Score=266, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6323409, Length=329, Percent_Identity=40.1215805471125, Blast_Score=245, Evalue=7e-66,
Organism=Drosophila melanogaster, GI45550998, Length=331, Percent_Identity=42.5981873111783, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19921562, Length=331, Percent_Identity=42.5981873111783, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16A1_ACAM1 (B0CAD9)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001517190.1
- ProteinModelPortal:   B0CAD9
- SMR:   B0CAD9
- GeneID:   5681683
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_2875
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- ProtClustDB:   PRK09293
- BioCyc:   AMAR329726:AM1_2875-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 39478; Mature: 39478

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00124 FBPASE

Important sites: BINDING 227-227 BINDING 255-255 BINDING 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSDSTSLELSYDFALDRDCTTLSRHVLEHLQSFSPEAQDMSALMTRIGLAGKLIARRL
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHH
SRAGLVEGALGFTGDINVQGEEVKKMDIYANEVFIAAFKQSGLVCRLASEEMEKPYYIPE
HHCCCCCCCCCCCCCCCCCHHHHEEEEEECCEEEEEEECCCCCEEEECHHHCCCCEECCC
NCPIGRYTLLYDPIDGSSNVDVNLNVGSIFSIRQQVGNDPDHTGQDLLQDGHQQIAAGYI
CCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEE
LYGPSTVLVYSIGKGVHVFILDPSLGEFILAAENLTIPKHGPVYSVNEGNFWQWEDALRD
EECCCEEEEEEECCCEEEEEECCCCCCEEEEECCEECCCCCCEEECCCCCCEEHHHHHHH
FTRYVHRHEGHTARYSGALVGDFHRILFQGGVFIYPGTLKNPDGKLRLLYESAPLAYLME
HHHHHHHCCCCCEEECCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHH
QAGGRASIGQSPLMDVVPDHLHARTPLIIGSTEDVALVESFIEDRERQAEEELALKS
HCCCCCCCCCCCCHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSSDSTSLELSYDFALDRDCTTLSRHVLEHLQSFSPEAQDMSALMTRIGLAGKLIARRL
CCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHH
SRAGLVEGALGFTGDINVQGEEVKKMDIYANEVFIAAFKQSGLVCRLASEEMEKPYYIPE
HHCCCCCCCCCCCCCCCCCHHHHEEEEEECCEEEEEEECCCCCEEEECHHHCCCCEECCC
NCPIGRYTLLYDPIDGSSNVDVNLNVGSIFSIRQQVGNDPDHTGQDLLQDGHQQIAAGYI
CCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEE
LYGPSTVLVYSIGKGVHVFILDPSLGEFILAAENLTIPKHGPVYSVNEGNFWQWEDALRD
EECCCEEEEEEECCCEEEEEECCCCCCEEEEECCEECCCCCCEEECCCCCCEEHHHHHHH
FTRYVHRHEGHTARYSGALVGDFHRILFQGGVFIYPGTLKNPDGKLRLLYESAPLAYLME
HHHHHHHCCCCCEEECCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHH
QAGGRASIGQSPLMDVVPDHLHARTPLIIGSTEDVALVESFIEDRERQAEEELALKS
HCCCCCCCCCCCCHHHCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA