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The map label for this gene is ddl [H]

Identifier: 158335744

GI number: 158335744

Start: 2635022

End: 2636014

Strand: Reverse

Name: ddl [H]

Synonym: AM1_2595

Alternate gene names: 158335744

Gene position: 2636014-2635022 (Counterclockwise)

Preceding gene: 158335745

Following gene: 158335743

Centisome position: 40.53

GC content: 51.36

Gene sequence:

>993_bases
ATGAAGATTGGCCTCCTGTTTGACTCCCAAGCGGAGCTGATGGCTGCACCAGAGGCCCAAGTCAACACCCACTACCATTG
GCGCGAACCGGAAGAAGTGGTTGCGGTGACCCATGCCCTCACGGATTTGGGCCATACCGTTGATGCTATTGGGTCCCTGG
AGAGTTTGCTTCACCGCTGGCAGCAGCAAGACCTGCCTGATCTAGTGTGGAATTTATCCGTAGGTGCTCTATCCCGCAAT
CGTACGGCTCTCGCTCCTGCGTTGTTAGAACACCTAGGCATTCCCTATACCGGTGGCGATGCGGCCACTAAAAGTTTGAC
CTTAAATAAAGACTGGCTCAAACCGGTTCTGGAATGGTGCGGCATTGCCACGCCACCTTGGCGTCGCTTTGGTTTGGAAG
AGTCGATTACAGAATTACCCCCTTGGCCCGTATCGCTACTGAAACCCACCTGTGAAGGTTATTCTTTAGGACTTCAAAGG
TTCGAGACCCAAGATGGGTTAGCGGTATTGCAGAAACAGGTGCAGCAACTTCAATCCCAGTTTCAAACCGCAGTACTTTG
TGAACCGTTGATTGCGGGGCGAGAAATTACGGTTGGGGTGGTTGGCAATCTCGAACCGAGTTTGCTGGGAGCTGTGGAAA
CTTTGACGACTTCAGGTCAGGCATTGCAGGAGCAAGTGTTGGATCTGCAAGCGAAGCGTCAGGGAGGGTTTCAGAAAGTC
AATGTTGATCTAGCCGATTCAGACTTACAGCCTCTGCGGAGTGCAGCTTTAAAGTTGATGAATCTGCTGCAGCCTTTGGA
TTATGCAACCTTCGATTTTCGGTTAGGCCGGGGGCAAGCCTATTTGGTGGATGTGAATGCCGATGCGACGTTACATCCTT
TGCGATCGCTTGCCCAAATCGCCCAAGCCCAAAAACTGACCTATCCACATTTAATTAAGCTGATTTTGATGACGACATGT
CACCGCTGGAGCCTGAGCCTCACAACTCCATAA

Upstream 100 bases:

>100_bases
TCGGTCGCTGGCACCAGCGGCGGCGGGGCAATGATTATCCTGACATTCTGTTTTTGCCGATTGATCCGCAAACGATGTGG
CTACCGGATGCTCTCCCACC

Downstream 100 bases:

>100_bases
GTTGATGTAAAGATGCATAATTCGCCTACCCGAGTGTGTCAAGTATGCTGTCAGGCTTATGCCTAAAAAATAACGTTCTC
CTGTGAAATATTCGAGAAAC

Product: D-alanine--D-alanine ligase A

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKIGLLFDSQAELMAAPEAQVNTHYHWREPEEVVAVTHALTDLGHTVDAIGSLESLLHRWQQQDLPDLVWNLSVGALSRN
RTALAPALLEHLGIPYTGGDAATKSLTLNKDWLKPVLEWCGIATPPWRRFGLEESITELPPWPVSLLKPTCEGYSLGLQR
FETQDGLAVLQKQVQQLQSQFQTAVLCEPLIAGREITVGVVGNLEPSLLGAVETLTTSGQALQEQVLDLQAKRQGGFQKV
NVDLADSDLQPLRSAALKLMNLLQPLDYATFDFRLGRGQAYLVDVNADATLHPLRSLAQIAQAQKLTYPHLIKLILMTTC
HRWSLSLTTP

Sequences:

>Translated_330_residues
MKIGLLFDSQAELMAAPEAQVNTHYHWREPEEVVAVTHALTDLGHTVDAIGSLESLLHRWQQQDLPDLVWNLSVGALSRN
RTALAPALLEHLGIPYTGGDAATKSLTLNKDWLKPVLEWCGIATPPWRRFGLEESITELPPWPVSLLKPTCEGYSLGLQR
FETQDGLAVLQKQVQQLQSQFQTAVLCEPLIAGREITVGVVGNLEPSLLGAVETLTTSGQALQEQVLDLQAKRQGGFQKV
NVDLADSDLQPLRSAALKLMNLLQPLDYATFDFRLGRGQAYLVDVNADATLHPLRSLAQIAQAQKLTYPHLIKLILMTTC
HRWSLSLTTP
>Mature_330_residues
MKIGLLFDSQAELMAAPEAQVNTHYHWREPEEVVAVTHALTDLGHTVDAIGSLESLLHRWQQQDLPDLVWNLSVGALSRN
RTALAPALLEHLGIPYTGGDAATKSLTLNKDWLKPVLEWCGIATPPWRRFGLEESITELPPWPVSLLKPTCEGYSLGLQR
FETQDGLAVLQKQVQQLQSQFQTAVLCEPLIAGREITVGVVGNLEPSLLGAVETLTTSGQALQEQVLDLQAKRQGGFQKV
NVDLADSDLQPLRSAALKLMNLLQPLDYATFDFRLGRGQAYLVDVNADATLHPLRSLAQIAQAQKLTYPHLIKLILMTTC
HRWSLSLTTP

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:
GO:0005524: D-alanine--D-alanine ligase A
GO:0008716: D-alanine--D-alanine ligase A
GO:0016874: D-alanine--D-alanine ligase A
GO:0046872: D-alanine--D-alanine ligase A
GO:0000166: D-alanine--D-alanine ligase
GO:0003824: D-alanine--D-alanine ligase
GO:0005618: D-alanine--D-alanine ligase
GO:0005737: D-alanine--D-alanine ligase
GO:0007047: D-alanine--D-alanine ligase
GO:0008360: D-alanine--D-alanine ligase
GO:0009252: D-alanine--D-alanine ligase

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 36441; Mature: 36441

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGLLFDSQAELMAAPEAQVNTHYHWREPEEVVAVTHALTDLGHTVDAIGSLESLLHRW
CEEEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQQDLPDLVWNLSVGALSRNRTALAPALLEHLGIPYTGGDAATKSLTLNKDWLKPVLEWC
HHCCCHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHCEEECCHHHHHHHHHHC
GIATPPWRRFGLEESITELPPWPVSLLKPTCEGYSLGLQRFETQDGLAVLQKQVQQLQSQ
CCCCCCHHHCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FQTAVLCEPLIAGREITVGVVGNLEPSLLGAVETLTTSGQALQEQVLDLQAKRQGGFQKV
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEE
NVDLADSDLQPLRSAALKLMNLLQPLDYATFDFRLGRGQAYLVDVNADATLHPLRSLAQI
EEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
AQAQKLTYPHLIKLILMTTCHRWSLSLTTP
HHHHHCCHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MKIGLLFDSQAELMAAPEAQVNTHYHWREPEEVVAVTHALTDLGHTVDAIGSLESLLHRW
CEEEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQQDLPDLVWNLSVGALSRNRTALAPALLEHLGIPYTGGDAATKSLTLNKDWLKPVLEWC
HHCCCHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHCEEECCHHHHHHHHHHC
GIATPPWRRFGLEESITELPPWPVSLLKPTCEGYSLGLQRFETQDGLAVLQKQVQQLQSQ
CCCCCCHHHCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FQTAVLCEPLIAGREITVGVVGNLEPSLLGAVETLTTSGQALQEQVLDLQAKRQGGFQKV
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEE
NVDLADSDLQPLRSAALKLMNLLQPLDYATFDFRLGRGQAYLVDVNADATLHPLRSLAQI
EEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
AQAQKLTYPHLIKLILMTTCHRWSLSLTTP
HHHHHCCHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]