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The map label for this gene is codY

Identifier: 153937667

GI number: 153937667

Start: 2412643

End: 2413419

Strand: Reverse

Name: codY

Synonym: CLC_2284

Alternate gene names: 153937667

Gene position: 2413419-2412643 (Counterclockwise)

Preceding gene: 153935195

Following gene: 153936674

Centisome position: 64.18

GC content: 27.67

Gene sequence:

>777_bases
ATGAGTTCATTACTAGATAAAACAAGAATGTTGAATAGAATATTGCAAAAATCAGGCACAGAGCCAGTAGATTTCGAAGA
TATATGTGATTTATTAAGTGACGTTTTAGCGTGTAACGTATATATAATTAGTAGAAAAGGAAAGATATTGGGATCTAAAT
TTTATTCAGGATTTGAATGTGACGAAGTAAGGGAAGTTGTTTTAAAAGAAAATAGATTTCCAGACTTCTACAATAATAAA
TTGTTAAATGTAAATGAAACTTTATCAAATTCACCTAACCATGATAAATGTGTATTTGATAATTTAAAGGATTGTTCAAT
AAATAATAAATTATCAACAATAGTTCCTATAAATGGAAATAGGGAAAGATTAGGTACATTATTATTAGCTAGATTTGATA
AAGAATTTACTGATGAAGATTTAGTGTTAGCAGAATACAGTGCTACAATAATTGGTCTTGAAATATTAAGATCAAAACAG
GATCAAATAGAAGAAGAAGCAAGAAAAAAAGCTGTAGTTCAACTAGCTATAGGAACATTATCTTATTCAGAATTAGAAGC
TGTAGAACATATATTTAATGAGTTAGATGGCACAGAAGGATTATTAGTAGCATCTAAAATAGCAGATAAAGTTGGAATAA
CAAGATCTGTTATAGTGAATGCATTAAGAAAATTTGAAAGTGCAGGGGTAATTGAATCAAGATCCCTAGGTATGAAAGGT
ACTCACATTAGAATATTAAATGATAAACTTTTAGAAGAATTAAAGAAGATAAAATAG

Upstream 100 bases:

>100_bases
ATATTTTTAATAGTCAAAATTTTTAAAGACATAATATGAAAAAGCAGCAGGAATCAATATATAAATTAAAGTAAAAGAGG
TAATAGAAGGAGGAAAACCC

Downstream 100 bases:

>100_bases
TAAAGAAGTCTTAGGACTTCTTTATTTTTTAGTACAATTATGAAATAATTCTTAGGTAGGATATTAATGGATAAAAATAC
GCCAAAATTTTTTTGAAATT

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFECDEVREVVLKENRFPDFYNNK
LLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGNRERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQ
DQIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
THIRILNDKLLEELKKIK

Sequences:

>Translated_258_residues
MSSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFECDEVREVVLKENRFPDFYNNK
LLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGNRERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQ
DQIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
THIRILNDKLLEELKKIK
>Mature_257_residues
SSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFECDEVREVVLKENRFPDFYNNKL
LNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGNRERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQD
QIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGT
HIRILNDKLLEELKKIK

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_CLOB1 (A7FPZ9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384611.1
- ProteinModelPortal:   A7FPZ9
- STRING:   A7FPZ9
- GeneID:   5395954
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2300
- eggNOG:   COG4465
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- BioCyc:   CBOT441770:CLB_2300-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 29043; Mature: 28912

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFEC
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHCCCCCH
DEVREVVLKENRFPDFYNNKLLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGN
HHHHHHHHHCCCCCCHHCCCEECCCHHHCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCC
RERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQDQIEEEARKKAVVQLAIGTL
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
SYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCC
THIRILNDKLLEELKKIK
CEEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFEC
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHCCCCCH
DEVREVVLKENRFPDFYNNKLLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGN
HHHHHHHHHCCCCCCHHCCCEECCCHHHCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCC
RERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQDQIEEEARKKAVVQLAIGTL
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
SYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCC
THIRILNDKLLEELKKIK
CEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA