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The map label for this gene is yclF [H]

Identifier: 153937298

GI number: 153937298

Start: 2321775

End: 2323172

Strand: Direct

Name: yclF [H]

Synonym: CLC_2189

Alternate gene names: 153937298

Gene position: 2321775-2323172 (Clockwise)

Preceding gene: 153937011

Following gene: 153937792

Centisome position: 61.74

GC content: 35.69

Gene sequence:

>1398_bases
ATGTCACAAGAAAAGCAAAAACATCCTATAGGCCTTTCACTAGTAAATATCTCTATAGCCCTCCAAAGTTATGCTGGATA
TGCAGTATCATCTGTATTAATATTATTCTTTACAGCTGATATCAACCGAAATGGCTTAGGCTTAAGCGTACCAAAAGCGG
CTTCTATCATCGGCCTATATCAAGGTGTCAATTATATGGGTTCTCTTGTTGGGGGATATATCACCGATAAATGGCTAGGA
ATTCAGAAATCACTGGCGTTAGGTTCTTTCCTAACTGCATGTGGATATATGGTGCTATTCTTTGCAAAGCCAAACATTGG
GAGTATCTGGTTAGGGCTTATTGTCTTAATTATAGCAGGTGCATTTTTCAAGGGACAAATTAGTACACTTGTAGGCTCGC
TCTATGATAAAAATGAATTATCTAAAAAATATGCTGCCTACAGCATATTCTATATGTTTATAAATATCGGTTCTTTCTTT
GGACCTATAATTGCAGGGTTAATCTCTGATAAATGGTTCGCTAAAGTAGCCGCTGATGGAGAAATTGCAGCCTATGGTTA
TAAATATATTTTTCTTATGTGTGCTATTGTCATGATAATTGTATGTGCTTTGATTTTGATTTTATCTCCTAAATGGTTGG
GGGATGTTGGAAAATACCCAACATCAAAAACTGAAGCTAAAAAAGCTTCCTCAAAATCCGAAGAAAAAGTTACAAACAAG
CCTTTGACACATACAGAAAAGAACCGTATTAAAGCGATGCTTGTCATGTTTCTATTTGTGATTATATTCTGGTCTGCATG
GTACCAAACTGCTACGTCTTTCTCTTTGCTTGCGGATAAACTAGTAAACAGAAAATTTGGTGGATTTACAATGCCTGTAC
CTTGGCTTACTTCTGTTAATGCGATCTTCTGCGTAGTGTTTTCCCCAATACTAGCAAATATCTGGGTAAAACTTGGAAAT
AGCAAAAAGGGTGATTTATCAGTTCCTACTAAAATGGGACTTGGATTGATTTTGGCAGCAGTTTCCTTTATTACCTTGAT
TTTGGGTATTTCCACATTAGACGGTGTCACAGACGGAAGTAGACAGATGAATATACTTTTTATCATTGTTGCTTACTTTT
TATTAACATTGGGTGAACTTTGCCTGTCTCCAATAAGAATGGCTATGTTCAATAAACTAGCTCCTGCTAAATTTAGCTCA
CTAGCAATGGGAGCATGGTACTTAAGTTTCTTTTTTTCAAACTTAATCTCAGGAAAACTAGCAGGATTCACAGATACCAT
AGGATATACAGAAATCTTTGGTTTTATAGCCGGTGTTGTAATCATATTTGGTTTAATCCTGATTTTATTAAGAAAGGGCT
TATTAAGGCTTATGTCTTTGGACGAATTTAATAAGTAA

Upstream 100 bases:

>100_bases
TAAAATTTCACCATACCTTACTGAAGAAGAAAAAAACTGGTTAAAGGAGTATACCAGAAAAATTTCATAATTAAGCCCAA
TTGAAATAAGGTATGTAACA

Downstream 100 bases:

>100_bases
ATAAGCACAAACAGCATATTACAAGTACAATAATACAAAAAAGACTATAATACTATTAACTATAGCACTATAGTCTTTTC
CTAACTTAAATGTTCCTTCA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLG
IQKSLALGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYDKNELSKKYAAYSIFYMFINIGSFF
GPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPTSKTEAKKASSKSEEKVTNK
PLTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKFGGFTMPVPWLTSVNAIFCVVFSPILANIWVKLGN
SKKGDLSVPTKMGLGLILAAVSFITLILGISTLDGVTDGSRQMNILFIIVAYFLLTLGELCLSPIRMAMFNKLAPAKFSS
LAMGAWYLSFFFSNLISGKLAGFTDTIGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK

Sequences:

>Translated_465_residues
MSQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLG
IQKSLALGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYDKNELSKKYAAYSIFYMFINIGSFF
GPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPTSKTEAKKASSKSEEKVTNK
PLTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKFGGFTMPVPWLTSVNAIFCVVFSPILANIWVKLGN
SKKGDLSVPTKMGLGLILAAVSFITLILGISTLDGVTDGSRQMNILFIIVAYFLLTLGELCLSPIRMAMFNKLAPAKFSS
LAMGAWYLSFFFSNLISGKLAGFTDTIGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK
>Mature_464_residues
SQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLYQGVNYMGSLVGGYITDKWLGI
QKSLALGSFLTACGYMVLFFAKPNIGSIWLGLIVLIIAGAFFKGQISTLVGSLYDKNELSKKYAAYSIFYMFINIGSFFG
PIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCAIVMIIVCALILILSPKWLGDVGKYPTSKTEAKKASSKSEEKVTNKP
LTHTEKNRIKAMLVMFLFVIIFWSAWYQTATSFSLLADKLVNRKFGGFTMPVPWLTSVNAIFCVVFSPILANIWVKLGNS
KKGDLSVPTKMGLGLILAAVSFITLILGISTLDGVTDGSRQMNILFIIVAYFLLTLGELCLSPIRMAMFNKLAPAKFSSL
AMGAWYLSFFFSNLISGKLAGFTDTIGYTEIFGFIAGVVIIFGLILILLRKGLLRLMSLDEFNK

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Escherichia coli, GI1789911, Length=490, Percent_Identity=25.7142857142857, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787922, Length=458, Percent_Identity=23.5807860262009, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790572, Length=395, Percent_Identity=24.0506329113924, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786927, Length=500, Percent_Identity=23, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50855; Mature: 50724

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQEKQKHPIGLSLVNISIALQSYAGYAVSSVLILFFTADINRNGLGLSVPKAASIIGLY
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH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CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]