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The map label for this gene is ftsK [H]

Identifier: 153936780

GI number: 153936780

Start: 2380201

End: 2382477

Strand: Reverse

Name: ftsK [H]

Synonym: CLC_2254

Alternate gene names: 153936780

Gene position: 2382477-2380201 (Counterclockwise)

Preceding gene: 153934679

Following gene: 153935820

Centisome position: 63.35

GC content: 29.78

Gene sequence:

>2277_bases
ATGGCAAAGAAAAGAACTAAATCTAATAAAACAGAAAAAAAGAATAATGATATAACAGGTATAATTCTAATAAGTATGGG
AATTTTTGTACTTTTTAGTGTGTTTTCCCCTTCTGCCTCTGGAATAGTTGGGAGTTTCATAAAAAAAGTACTTATAGCTG
TATTAGGTTTAGGATCTTTAGTATTTCCAATACTAATAATATTCACAGGATGTTGCTTTATAGGAAAGAAGAATAAAATA
AATTTGAACTCTAAATTTTATGGAATAGTTCTTTTTTCTATAAATACACTTTTATTTTTACAAATGATACTTTTAAAAAG
TTATGGCACAGAAGATATAATGCTTGGCATATCAAAATTTTATAGAGAAGATACAATGATTCATGGTGGTATAATTTCTT
ATCTAATAGATGTTCCTTTATATAAACTGTTTGGAACTATAGGATGTTACATATTGTTTATATGTGTTTATATAATAAGC
TTTATATTAATATTTCAAGTATCTTTAGGTACTATACTACAGACTTTACAGGTAAAAAGAAGTATAAAAAATAAAAAAGT
TAAAGAAAAATCTATAGAAGATAAAGAAGACATAGACGGTATAGAAAAAGAATTAGCTCCGGACTTAGAAAAAGATGAAG
GTTTAACTAGGAATATTAAAGACAAAATCAAAATATTAGATTTTATGAAAAACTCAGAAATAAAGGAAGGTCCACTAAAT
ATTGTGGATAATTCTGTTAGTGAAAACATAGAAAAATCTAAAGAAGATACCGGGGAAGAGGCTATAAAAGAAGAACTTAG
TAAAAATATAAATGAAGGGGGAAACAATGTAAAAATAGAATATAACTATCCAACCTTAGAACTTTTAAAACAAAATATTC
AGTCAAAACTAAATAAACAAGATAAAAAAGAACTTATAAATAACGCAAATAAGTTAGAGGAAACTTTAAGTAGTTTTGGT
GTAGAAGCTAAAGTTATGCAAGTAAGTAGAGGACCTTCAGTTACAAGGTTTGAACTTCAACCTAATGCGGGAGTTAAAGT
AAGTAAAATAGTAAATTTAGCAGACGATATAGCGCTAAATTTAGCAGCTTCAGGAGTTAGAATAGAGGCTCCTATACCAG
GAAAATCTGCAGTAGGTATAGAAGTGCCAAACAAATCCTTAACACCGGTATATTTAAGAGAAGTTATAGAAGGAGATGAA
TTTCAGAAATTTGATGATGGACTAGCTTTTGCTTTGGGAAAGGATATAAGTGGTAGTTGTGTAGTATCAGATTTATCAAA
AATGCCTCACCTATTAATAGCAGGAGCTACAGGTTCAGGAAAAAGTGTATGTATAAATACATTAATAATAAGTATTTTAT
ATAAATATTCTCCAGAAAATGTAAAATTACTTATGGTGGATCCAAAGGTAGTAGAGCTTAGCATATATAATGGTATACCT
CATTTATTGATTCCAGTAGTTACAGATCCTAAAAAAGCGGCAGGAGCTCTTCATTGGGCAGTAAATGAAATGACAAAGAG
ATATTCTTTATTTGCAGAAAATAGTGTAAGAAATATAGAGGGATATAATAATTTATATGACCAGGGTAAAATAGAAAATA
AATTACCTTATGTGGTAATAATAATAGATGAGCTTGCAGATTTAATGATGGTTTGTCCAAATGATATAGAAGACTACATA
AGTAGATTAGCTCAAATGGCTAGAGCAGCAGGTATGCATTTAGTTATAGCAACACAAAGACCTTCTGTAGATGTTATAAC
AGGAATAATAAAGGCAAATATACCTTCTAGAATATCCTTTGCAGTATCTAGTTCTATAGATTCTAGAACCATATTAGATA
TGTCAGGAGCAGAAAAACTTTTAGGAAAAGGAGATATGTTATTTTATCCAACAGGATCTCCAAAACCTACTAGAATACAA
GGAGCTTTTATATCTGAAAGTGAAGTGGAAAAGGTAGTTTCATGTATAAAGGATGAGCAAGGAGAAGCAGAATATAGAGA
AGAAATAATAGATCAAATAGATACAGCTGTAAATGTAGAAGCCGGGGATGAGGATGAGCTTCTAGAAGAGGCTATAAGAA
TATGTATACAATTAGGAGAGGTATCCACATCACTAATTCAAAGAAAACTTAGAATAGGATATAATAGGGCAGCAAGAATA
ATAGAACAGCTAGAAGCTAAGGGAATAATTTCCGGAAGAGATGGTAATAAACCAAGACAAGTAATAATTGATAAAAACAA
TGAAACCTACGGAAAATATTTCCGAGGAAATATGTAA

Upstream 100 bases:

>100_bases
AGGTATGCATTAATTAATATAAAAGGATATAAAAGTTCAATGTAGAATCTATAAATGTAGCTTAAATTAAACATTACTAG
TTGGGAGGTGAATTAAAAGT

Downstream 100 bases:

>100_bases
ATACTTTTAAAATTCAAGTTACTTAATACTTGTAAAATTTCTTAAGTAGATTTAAAATGTTTCTTGTGACATAAAAAATG
TAGGAGGGGAACAGGTGGAA

Product: DNA translocase FtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 757

Protein sequence:

>758_residues
MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKI
NLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIIS
FILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN
IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFG
VEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDE
FQKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP
HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYI
SRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQ
GAFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI
IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM

Sequences:

>Translated_758_residues
MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKI
NLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIIS
FILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN
IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFG
VEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDE
FQKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP
HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYI
SRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQ
GAFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI
IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
>Mature_757_residues
AKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKIN
LNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISF
ILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLNI
VDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFGV
EAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEF
QKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIPH
LLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYIS
RLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQG
AFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARII
EQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=48.1481481481481, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83911; Mature: 83779

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSL
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VFPILIIFTGCCFIGKKNKINLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKF
HHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISFILIFQVSLGTILQTLQVKR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQ
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCHH
DKKELINNANKLEETLSSFGVEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALN
HHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEFQKFDDGLAFALGKDISGSC
EECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCH
VVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCC
HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVI
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCEEEE
IIDELADLMMVCPNDIEDYISRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISF
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEH
AVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQGAFISESEVEKVVSCIKDEQ
HHHCCCCCCEEEECCCHHHHHCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
GEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI
CCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
HHHHHHCCEEECCCCCCCCEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
AKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSL
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VFPILIIFTGCCFIGKKNKINLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKF
HHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISFILIFQVSLGTILQTLQVKR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQ
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCHH
DKKELINNANKLEETLSSFGVEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALN
HHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEFQKFDDGLAFALGKDISGSC
EECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCH
VVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCC
HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVI
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCEEEE
IIDELADLMMVCPNDIEDYISRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISF
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEH
AVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQGAFISESEVEKVVSCIKDEQ
HHHCCCCCCEEEECCCHHHHHCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
GEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI
CCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
HHHHHHCCEEECCCCCCCCEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]