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The map label for this gene is ceo

Identifier: 153936762

GI number: 153936762

Start: 603191

End: 604144

Strand: Direct

Name: ceo

Synonym: CLC_0588

Alternate gene names: 153936762

Gene position: 603191-604144 (Clockwise)

Preceding gene: 153936609

Following gene: 153936724

Centisome position: 16.04

GC content: 29.98

Gene sequence:

>954_bases
ATGAAATTAGGATTTTTGATACCAAATCATCCAAATGAAAAAAGAGTTGCTTTATTACCAGAACATGTTAAAGGTTTTAA
CAATGAGCTAGTTATAGAAACAGGTTTTGGTGAAACTCTAGGGATTTCAGATGCAGAATATGTAAAGGTAGGTTGCACTA
TAGCTTCTCGAGAAGAAATATTTAAAACCTGTGAAGGTATATTTTCATTAAAGGTTTTAAAGCCTCAGGACTATAAGCAT
ATAAGAGAAGGCCAAATTATAGTGGGCTGGACACATCCAGAGGGATCAGGAAAAATATTTATGGAAGAACAGGGCATACC
TAAAAATTTAATTATAGTAGATTTAGATAATATTCATCCTTCAATCTATTATAAAGATTATGTAATACCAATGGAGTGGA
TTCCATCTAACTTTGTAAGAAAAAATAGCTATATAGCAGGTTATGCATCTACTATGCATGCAGTTATGAATTATGGAAGT
ATACCAACTTCAGAAACTAAAGTTGCTATATTAGGATCAGGTAACGTATCTCAAGGTGCTTTTTCAGCAATATCTAAATT
TAATCCAGATATAAGAATGTTTTATAGAAAAACTATGAATCAATTAAAAGATGAGTTAGAAGAATTTGATATAATAATAA
ATGGAATAGAAATGGATAATCCTAATAAGCATATACTAACTTTAGAAGATCAAATGAGATTAAAGAAAAATTGTTTAATT
ATAGATGCAGCGGCTAACCTTGGAAAAGCTATAGAAGGTGCAAGACATACTACAGCATCCGATCCTATATACAATAAGGA
TGGAAAATACTATTATGCAGTTAATAATTCTCCATCTATATTTTATAGACAATCCAGTAAGGCTATAAGTGAAGCTTTCA
GTAAACATGTATACAGCAAAGAATTAGAATTTTATTTAGATGTTATTGCAGAAGTAGAGGAAATGATAGTATAA

Upstream 100 bases:

>100_bases
ATGTTATTGATATTTAACAACTTTATATATGCTATAAAGTTGTAACTATAATAAATATTGTTAAATATTATAGTTATTGT
ATAAATAAAGGAGGTTATAT

Downstream 100 bases:

>100_bases
AGAATTTTATTATGAATAATAAACTGAAAAACCCTATAATTAAGTGTAGTATTTAATTGATGTAAAATACTATACACTAT
AAAATAAAAAGGTAGGTAAT

Product: N(5)-(carboxyethyl)ornithine synthase

Products: NA

Alternate protein names: CEOS; N(5)-(L-1-carboxyethyl)-L-ornithine:NADP(+) oxidoreductase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLGFLIPNHPNEKRVALLPEHVKGFNNELVIETGFGETLGISDAEYVKVGCTIASREEIFKTCEGIFSLKVLKPQDYKH
IREGQIIVGWTHPEGSGKIFMEEQGIPKNLIIVDLDNIHPSIYYKDYVIPMEWIPSNFVRKNSYIAGYASTMHAVMNYGS
IPTSETKVAILGSGNVSQGAFSAISKFNPDIRMFYRKTMNQLKDELEEFDIIINGIEMDNPNKHILTLEDQMRLKKNCLI
IDAAANLGKAIEGARHTTASDPIYNKDGKYYYAVNNSPSIFYRQSSKAISEAFSKHVYSKELEFYLDVIAEVEEMIV

Sequences:

>Translated_317_residues
MKLGFLIPNHPNEKRVALLPEHVKGFNNELVIETGFGETLGISDAEYVKVGCTIASREEIFKTCEGIFSLKVLKPQDYKH
IREGQIIVGWTHPEGSGKIFMEEQGIPKNLIIVDLDNIHPSIYYKDYVIPMEWIPSNFVRKNSYIAGYASTMHAVMNYGS
IPTSETKVAILGSGNVSQGAFSAISKFNPDIRMFYRKTMNQLKDELEEFDIIINGIEMDNPNKHILTLEDQMRLKKNCLI
IDAAANLGKAIEGARHTTASDPIYNKDGKYYYAVNNSPSIFYRQSSKAISEAFSKHVYSKELEFYLDVIAEVEEMIV
>Mature_317_residues
MKLGFLIPNHPNEKRVALLPEHVKGFNNELVIETGFGETLGISDAEYVKVGCTIASREEIFKTCEGIFSLKVLKPQDYKH
IREGQIIVGWTHPEGSGKIFMEEQGIPKNLIIVDLDNIHPSIYYKDYVIPMEWIPSNFVRKNSYIAGYASTMHAVMNYGS
IPTSETKVAILGSGNVSQGAFSAISKFNPDIRMFYRKTMNQLKDELEEFDIIINGIEMDNPNKHILTLEDQMRLKKNCLI
IDAAANLGKAIEGARHTTASDPIYNKDGKYYYAVNNSPSIFYRQSSKAISEAFSKHVYSKELEFYLDVIAEVEEMIV

Specific function: Catalyzes the NADPH-dependent reductive condensation between pyruvic acid and the side chain amino group of L-ornithine to form N(5)-(L-1-carboxyethyl)-L-ornithine. To a lesser extent, can also use L-lysine as substrate (yielding N(6)-(L-1- carboxyethyl)-

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family. CEOS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CEO_CLOBH (A5HZ59)

Other databases:

- EMBL:   CP000727
- EMBL:   AM412317
- RefSeq:   YP_001253058.1
- RefSeq:   YP_001386471.1
- ProteinModelPortal:   A5HZ59
- GeneID:   5184770
- GeneID:   5398896
- GenomeReviews:   AM412317_GR
- GenomeReviews:   CP000727_GR
- KEGG:   cbh:CLC_0588
- KEGG:   cbo:CBO0515
- eggNOG:   COG0686
- HOGENOM:   HBG419660
- OMA:   SCDEGMG
- ProtClustDB:   CLSK876855
- BioCyc:   CBOT36826:CBO0515-MONOMER
- BioCyc:   CBOT441771:CLC_0588-MONOMER
- GO:   GO:0005488
- InterPro:   IPR007698
- InterPro:   IPR007886
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N

EC number: =1.5.1.24

Molecular weight: Translated: 35850; Mature: 35850

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: BINDING 15-15 BINDING 71-71 BINDING 92-92

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGFLIPNHPNEKRVALLPEHVKGFNNELVIETGFGETLGISDAEYVKVGCTIASREEI
CEEEEECCCCCCCCEEEECCHHHCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCHHHH
FKTCEGIFSLKVLKPQDYKHIREGQIIVGWTHPEGSGKIFMEEQGIPKNLIIVDLDNIHP
HHHHHHHEEEEEECCCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCC
SIYYKDYVIPMEWIPSNFVRKNSYIAGYASTMHAVMNYGSIPTSETKVAILGSGNVSQGA
EEEEEEEEEEHHHCCCCHHHCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
FSAISKFNPDIRMFYRKTMNQLKDELEEFDIIINGIEMDNPNKHILTLEDQMRLKKNCLI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEHHHHHHHHCEEE
IDAAANLGKAIEGARHTTASDPIYNKDGKYYYAVNNSPSIFYRQSSKAISEAFSKHVYSK
EECCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
ELEFYLDVIAEVEEMIV
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLGFLIPNHPNEKRVALLPEHVKGFNNELVIETGFGETLGISDAEYVKVGCTIASREEI
CEEEEECCCCCCCCEEEECCHHHCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCHHHH
FKTCEGIFSLKVLKPQDYKHIREGQIIVGWTHPEGSGKIFMEEQGIPKNLIIVDLDNIHP
HHHHHHHEEEEEECCCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCC
SIYYKDYVIPMEWIPSNFVRKNSYIAGYASTMHAVMNYGSIPTSETKVAILGSGNVSQGA
EEEEEEEEEEHHHCCCCHHHCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
FSAISKFNPDIRMFYRKTMNQLKDELEEFDIIINGIEMDNPNKHILTLEDQMRLKKNCLI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEHHHHHHHHCEEE
IDAAANLGKAIEGARHTTASDPIYNKDGKYYYAVNNSPSIFYRQSSKAISEAFSKHVYSK
EECCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHH
ELEFYLDVIAEVEEMIV
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA