Click here to switch to the map view.

The map label for this gene is ycaM [H]

Identifier: 153936418

GI number: 153936418

Start: 2307116

End: 2308519

Strand: Reverse

Name: ycaM [H]

Synonym: CLC_2169

Alternate gene names: 153936418

Gene position: 2308519-2307116 (Counterclockwise)

Preceding gene: 153935842

Following gene: 153934842

Centisome position: 61.39

GC content: 30.41

Gene sequence:

>1404_bases
ATGTCAAAAAATAAAGACAAGCGAATTGCTTGGTATATGCTTGCTTTTATGGCATTTTCCACTGTATGGGGTTTTGGTAA
TGTTATTAATGGTTTCTCAGAATACGAAGGGCTTAAAGCAATTGTTTCTTGGATTATAATTTTTGCTATTTATTTTGTAC
CATATGCTTTAATGGTGGGTGAATTGGGATCAGCATTTAAAGATTATGGGGGAGGAGTAAGTTCATGGATACATGAAACT
ATAGGGCCTAAACTTGCATATTATGCTGGATGGACGTATTGGGTGGTTCATATGCCTTATATTTCACAAAAACCATCAGG
TCTTATGATTGCGACAAGCTGGGCTATTTTTCAAGACAAAAGAATTAGTTCAATGAATACAAAACTTATGCAATTAATTT
GTTTGGTGATCTTTTTAATTGCCATCTATATTGCATCAAAGGGATTAAATCCACTAAAGAAATTAGCAACACTTGCAGGA
ACATCAATGTTTGTAATGTCTATTTTATTTATTATTTTAATGATAGCAGCACCTGCAATTACAAATGCACATTTAAATCA
AATTGATTGGTCTTTTAAAACCTTTATGCCAACTTTTGATACAAAATTTTTTACTAATTTAGCTATTTTGGTATTTGCTG
TGGGAGGATGTGAAAAAATATCACCCTATGTTAATAAAATGGAAAATCCGGAAACAGGATTTTCAAAAGGTATGATTGCC
TTAGCAATTATGGTAGCTGTATGTGCAATTTTAGGTACAGTTTCCCTTGGCATGATGTTTGATTCAAATAATGTTCCTAA
AGATTTAATGACTAATGGGGCATATTATGCATTTCAAAAATTAGGTGAATATTATAAATTGGGTAATACATTTGTAATTA
TATATGCAATTACAAATATTATTGCACAATTTGCTGTATTAATTATATCAATTGATGCACCTTTACGCATGTTACTTGAT
AGTGCAGATGAACGTTTTATCCCTAAAAAAATGTTTGAAAAGAATAAATACGGTGCATATAAAAATGGTAATAAACTTAT
TTTAGTAATTGTATCAATTTTAATTGTAGTACCAGCTTTAGGTATTGGTAGTGTAGATGAATTAGTAAAATGGTTAGTAA
AATTAAATGCTGTGTGTATGCCACTTCGTTATTTATGGGTATTTGCTGCATATATTGCATTGAAAAAAGCAGGAGAAAAG
TTTAATAGAGAATATTATTTTGTAAAGAATAATACACTAGGTATTATTTTAGGAGCATGGTGTTTTGTCTTTACAGCTTT
TGCATGCATTGGTGGCATGTACTCTACTGATATGTTTAAACTAGTACTTAATATTGTGACACCATTTGTACTAATAGGTT
TAGGTGTAATTATGCCTTATCTTGCAAAAAAGAATAATGCTTAG

Upstream 100 bases:

>100_bases
GTAGTTGCAATAATAAGAAAATCTGAGGGGAGTAAATAGATTATGAACGCAATAACTTATTATTTTAACGAGAATATTAA
AAGTATGAGAGGAGTATATC

Downstream 100 bases:

>100_bases
TAATTTATAGACAAACTTTAATTAAAAATTATATTAATGTAAAAAAATATCATTGTTTTTAATAAATTTCAGGCTGTTGA
CAAATATATTTTGTCAACAG

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSKNKDKRIAWYMLAFMAFSTVWGFGNVINGFSEYEGLKAIVSWIIIFAIYFVPYALMVGELGSAFKDYGGGVSSWIHET
IGPKLAYYAGWTYWVVHMPYISQKPSGLMIATSWAIFQDKRISSMNTKLMQLICLVIFLIAIYIASKGLNPLKKLATLAG
TSMFVMSILFIILMIAAPAITNAHLNQIDWSFKTFMPTFDTKFFTNLAILVFAVGGCEKISPYVNKMENPETGFSKGMIA
LAIMVAVCAILGTVSLGMMFDSNNVPKDLMTNGAYYAFQKLGEYYKLGNTFVIIYAITNIIAQFAVLIISIDAPLRMLLD
SADERFIPKKMFEKNKYGAYKNGNKLILVIVSILIVVPALGIGSVDELVKWLVKLNAVCMPLRYLWVFAAYIALKKAGEK
FNREYYFVKNNTLGIILGAWCFVFTAFACIGGMYSTDMFKLVLNIVTPFVLIGLGVIMPYLAKKNNA

Sequences:

>Translated_467_residues
MSKNKDKRIAWYMLAFMAFSTVWGFGNVINGFSEYEGLKAIVSWIIIFAIYFVPYALMVGELGSAFKDYGGGVSSWIHET
IGPKLAYYAGWTYWVVHMPYISQKPSGLMIATSWAIFQDKRISSMNTKLMQLICLVIFLIAIYIASKGLNPLKKLATLAG
TSMFVMSILFIILMIAAPAITNAHLNQIDWSFKTFMPTFDTKFFTNLAILVFAVGGCEKISPYVNKMENPETGFSKGMIA
LAIMVAVCAILGTVSLGMMFDSNNVPKDLMTNGAYYAFQKLGEYYKLGNTFVIIYAITNIIAQFAVLIISIDAPLRMLLD
SADERFIPKKMFEKNKYGAYKNGNKLILVIVSILIVVPALGIGSVDELVKWLVKLNAVCMPLRYLWVFAAYIALKKAGEK
FNREYYFVKNNTLGIILGAWCFVFTAFACIGGMYSTDMFKLVLNIVTPFVLIGLGVIMPYLAKKNNA
>Mature_466_residues
SKNKDKRIAWYMLAFMAFSTVWGFGNVINGFSEYEGLKAIVSWIIIFAIYFVPYALMVGELGSAFKDYGGGVSSWIHETI
GPKLAYYAGWTYWVVHMPYISQKPSGLMIATSWAIFQDKRISSMNTKLMQLICLVIFLIAIYIASKGLNPLKKLATLAGT
SMFVMSILFIILMIAAPAITNAHLNQIDWSFKTFMPTFDTKFFTNLAILVFAVGGCEKISPYVNKMENPETGFSKGMIAL
AIMVAVCAILGTVSLGMMFDSNNVPKDLMTNGAYYAFQKLGEYYKLGNTFVIIYAITNIIAQFAVLIISIDAPLRMLLDS
ADERFIPKKMFEKNKYGAYKNGNKLILVIVSILIVVPALGIGSVDELVKWLVKLNAVCMPLRYLWVFAAYIALKKAGEKF
NREYYFVKNNTLGIILGAWCFVFTAFACIGGMYSTDMFKLVLNIVTPFVLIGLGVIMPYLAKKNNA

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081798, Length=471, Percent_Identity=52.0169851380042, Blast_Score=520, Evalue=1e-149,
Organism=Escherichia coli, GI87082380, Length=441, Percent_Identity=22.2222222222222, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994921, Length=421, Percent_Identity=23.5154394299287, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52131; Mature: 52000

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNKDKRIAWYMLAFMAFSTVWGFGNVINGFSEYEGLKAIVSWIIIFAIYFVPYALMVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGSAFKDYGGGVSSWIHETIGPKLAYYAGWTYWVVHMPYISQKPSGLMIATSWAIFQDK
HHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCEEEEEECCHHCCCCCCEEEEEEHHHHHHH
RISSMNTKLMQLICLVIFLIAIYIASKGLNPLKKLATLAGTSMFVMSILFIILMIAAPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHH
TNAHLNQIDWSFKTFMPTFDTKFFTNLAILVFAVGGCEKISPYVNKMENPETGFSKGMIA
CCCHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCHHHHHCCCCCCCHHHHHHH
LAIMVAVCAILGTVSLGMMFDSNNVPKDLMTNGAYYAFQKLGEYYKLGNTFVIIYAITNI
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
IAQFAVLIISIDAPLRMLLDSADERFIPKKMFEKNKYGAYKNGNKLILVIVSILIVVPAL
HHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
GIGSVDELVKWLVKLNAVCMPLRYLWVFAAYIALKKAGEKFNREYYFVKNNTLGIILGAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
CFVFTAFACIGGMYSTDMFKLVLNIVTPFVLIGLGVIMPYLAKKNNA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKNKDKRIAWYMLAFMAFSTVWGFGNVINGFSEYEGLKAIVSWIIIFAIYFVPYALMVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGSAFKDYGGGVSSWIHETIGPKLAYYAGWTYWVVHMPYISQKPSGLMIATSWAIFQDK
HHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCEEEEEECCHHCCCCCCEEEEEEHHHHHHH
RISSMNTKLMQLICLVIFLIAIYIASKGLNPLKKLATLAGTSMFVMSILFIILMIAAPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHH
TNAHLNQIDWSFKTFMPTFDTKFFTNLAILVFAVGGCEKISPYVNKMENPETGFSKGMIA
CCCHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCHHHHHCCCCCCCHHHHHHH
LAIMVAVCAILGTVSLGMMFDSNNVPKDLMTNGAYYAFQKLGEYYKLGNTFVIIYAITNI
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEHHHHHHHH
IAQFAVLIISIDAPLRMLLDSADERFIPKKMFEKNKYGAYKNGNKLILVIVSILIVVPAL
HHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
GIGSVDELVKWLVKLNAVCMPLRYLWVFAAYIALKKAGEKFNREYYFVKNNTLGIILGAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
CFVFTAFACIGGMYSTDMFKLVLNIVTPFVLIGLGVIMPYLAKKNNA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]