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The map label for this gene is treP [H]

Identifier: 153936138

GI number: 153936138

Start: 2052475

End: 2053902

Strand: Direct

Name: treP [H]

Synonym: CLC_1933

Alternate gene names: 153936138

Gene position: 2052475-2053902 (Clockwise)

Preceding gene: 153935795

Following gene: 153936849

Centisome position: 54.58

GC content: 33.96

Gene sequence:

>1428_bases
ATGTCTAAGTTTTCAAATGACGTACAGCAATTGTTAGAATATATTGGGGGAAAAGAGAATATTTCCGCAGTAACCCATTG
TGCAACCCGTATGCGTTTTGTACTACAGGATGTTAAAAAAGCAGATATTAAAAACATTGAAAAAATTAAATCTGTAAAGG
GAGTTTTTACACAGGCTGGTCAATTTCAGGTCATTGTAGGAAATGAAGTTTCAACATTTTATAATGAATTTGTAAAGATA
GCTAAAGTAGGCGGCGTTAGTAAAGATCAAGCCAAAGTAGCTGCTAAAAACAATATGAATTTTATGCAAAAACTACTAGC
TAATTTAGCAGAAATATTCGCTCCTATTATACCTGCTCTTATAGTTGGAGGCCTAATATTAGGATTCCGTAATATTATTG
GAGATATTAAATTAGTGGAAAATGGAACTAAAACTTTAATACAAGTATCTCAATTTTGGCAAGGTGTTCATTCCTTCTTA
TGGCTAATTGGCGAAGCAATATTCTTCTTCTTACCTGTTGGAATAACTTGGTCTATTTCTAAAAAGATGGGCACCACACA
AATTTTAGGAATCATATTAGGACTTACTCTAGTTTCTCCTCAACTATTAAATGCTTATTCTGCTGCAGGTACTCCTGTAG
ATAAAATTCCAGTATGGAACTTCGGTTTTGCAAAAATTCAAATGATTGGTTATCAAGCACAAGTAATTCCATCAATGCTA
GCAGGATTCCTTTTAGCCTGGTTAGAAAAATCTATGCGAAAAATTGTACCAGAATATATTTCCATGATTTTAGTACCTTT
TCTTTCGCTAGTACCTACTGTATTAATAGCTCATACTATTTTAGGACCAGTAGGCTGGAAAATAGGTACAGTTATAGCAA
ACGTAGTATATTCAAGTTTAACTTCAACCTTTGGCTGGCTATTTGCGGCTGTATTTGGATTTACCTATGCGCCTTTAGTT
ATTACAGGATTACATCATATGACTAACGCTATTGATCTACAAATAATGGCCGAACTTGGCGGAACTAATTTATGGCCAAT
GATTGCCCTATCCAATATAGCTCAAGGCTCTGCAGTTTTAGCAATGATTTATTTAAATAAAAATAACGAAGAAGAAAAAC
AGGTATCTATTCCCGCAGCAATCTCCTGTTATCTAGGGGTAACGGAGCCAGCTATATTTGGTATAAATCTAAAGTATATA
TTTCCTTTTTTAGCTGCTATGATAGGCTCTTCAATAGCTGCAGTCATATCAGTAGGCTCAAACGTTATGGCTAATTCAAT
TGGAGTTGGTGGCCTACCAGGTATACTGTCTATAAAACCACAATACATGTTATCTTTTGCATTAGCAATGCTAGTAGCTA
TTGTTGTACCTTTTATACTTACAATTGTGTTTTCTAAGAAAAAAAAGTGGAGTAAAAAAATACAATAA

Upstream 100 bases:

>100_bases
TACGTACAAGATATAATTTATTTATCGCACTTGTACGTACATCTTTCTGATAAATAAAAATATTTACGAAAGTATAAATA
ATAAAGGGGGATTATTTAAT

Downstream 100 bases:

>100_bases
ACCAATTATATCTTAAAATAGAAAAGGAGGATTAAATTCCTTCCTTTTCTAATTCATATTTAAACAAAAGGAGCAAATTA
CATGAAAGATTTTAAAAAAA

Product: PTS system, trehalose-specific IIBC component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKI
AKVGGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFL
WLIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML
AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLV
ITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYI
FPFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ

Sequences:

>Translated_475_residues
MSKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKI
AKVGGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFL
WLIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML
AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLV
ITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYI
FPFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ
>Mature_474_residues
SKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAGQFQVIVGNEVSTFYNEFVKIA
KVGGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPALIVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFLW
LIGEAIFFFLPVGITWSISKKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSMLA
GFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSLTSTFGWLFAAVFGFTYAPLVI
TGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVLAMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYIF
PFLAAMIGSSIAAVISVGSNVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=470, Percent_Identity=52.3404255319149, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI48994906, Length=465, Percent_Identity=29.0322580645161, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1790159, Length=417, Percent_Identity=26.1390887290168, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788769, Length=495, Percent_Identity=24.8484848484848, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51629; Mature: 51498

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKFSNDVQQLLEYIGGKENISAVTHCATRMRFVLQDVKKADIKNIEKIKSVKGVFTQAG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QFQVIVGNEVSTFYNEFVKIAKVGGVSKDQAKVAAKNNMNFMQKLLANLAEIFAPIIPAL
CEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IVGGLILGFRNIIGDIKLVENGTKTLIQVSQFWQGVHSFLWLIGEAIFFFLPVGITWSIS
HHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
KKMGTTQILGIILGLTLVSPQLLNAYSAAGTPVDKIPVWNFGFAKIQMIGYQAQVIPSML
HHCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHH
AGFLLAWLEKSMRKIVPEYISMILVPFLSLVPTVLIAHTILGPVGWKIGTVIANVVYSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TSTFGWLFAAVFGFTYAPLVITGLHHMTNAIDLQIMAELGGTNLWPMIALSNIAQGSAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEE
AMIYLNKNNEEEKQVSIPAAISCYLGVTEPAIFGINLKYIFPFLAAMIGSSIAAVISVGS
EEEEECCCCCHHHHCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC
NVMANSIGVGGLPGILSIKPQYMLSFALAMLVAIVVPFILTIVFSKKKKWSKKIQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]