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The map label for this gene is ycxD [H]

Identifier: 153934654

GI number: 153934654

Start: 2080408

End: 2081754

Strand: Reverse

Name: ycxD [H]

Synonym: CLC_1959

Alternate gene names: 153934654

Gene position: 2081754-2080408 (Counterclockwise)

Preceding gene: 153936516

Following gene: 153937730

Centisome position: 55.36

GC content: 28.88

Gene sequence:

>1347_bases
ATGTATAAATATTTAGAAATATTAAATCATGTTGAGAGCTTAATTCAAGAGGGGGAGTATAAAGATGGGGATAAGTTACC
CTCTATTCGTGATTTTACTAAGATATATTCCTGCAATAAAAGTACTATTATAAAAGCTTTAGAGGCGTTAGAGAGACAGC
ATAGGATATATTCCATACCTAAGAGTGGTTATTATGTTGTAAGGAGAAAAAATCCTACCAATAGTAATAAAGAAGTATTA
TTAGATTTTGCATCCTCTGCTCCAGATCCACAGGTTTTTCCCTATCTAGATTTTCAACATTGTATTAATGAAGCCATTGA
TATATATAAGAATGAAATATTTATTTATGGGACACCTAAAGGATTACCTTCTTTAATTGATGTAATACAAAAACATTTAG
CCGATTATCAGGTTTTTGCTAATAGAGATAATATTTTTATTACCTCTGGAGTTCAGCAAGCTTTAGCTATACTAACTACA
CTAACTTTTCCAAATAAAAAGGAAACTATTTTAATAGAACAACCTAGTTATCATTTATTTATAGATTATTTAGAAACTCA
TAATGTTCCTGTATTAGGCATTAAAAGGACGGATAAAGGTATTGATTTAAATGAACTTGAGAGATTATTTAAAACGGAAA
GTATTAAGTTCTTCTATACTATGCCTAGGTTTCATAATCCTTTAGGAACTTCTTATTCTCAAAGAGAAAAGGAAGCTATT
GTAAAGCTAGCTGAAAAATATGATGTATTTATTGTGGAAGATGACTATTTAGCAGATTTAGAAGAGGATCCAAAGGCTGA
TCCCTTATATGCCTATGGTGATTTTTCCCATGTTATCTATTTAAAGAGTTATTCAAAAATTATATTTCCTGGACTTAGAA
TAGGAGTTGCGGTTATTCCTAATACCATTTTAGAGAGCTTTGGAAAATATAAAAGACTTATAGATGTAGATAGTTCCATG
CTCTCTCAAGGAGCCTTAGAAATTTATATTAAAAGTGGTATGTTTCAAAGACACAAACAAAAGATTAGGACTTCTTATTC
TTTAAGAAGTAAATGCTTAGATTCAATTCTACAAAAACAATATAAAATTTATAGTGATGTTTTTCAGTATAACCCTATTA
AAAATCCATGTATTCATACATACATAAACTTTAATGGCAAAATAAATAGAGAAAGACTCATAGATAGATTGAAAAAGAAA
TCTATTATTGTGGCTACAGAGAGGGGACATTATTTAAGCACATTTTCAAGGGAAAAGATTCTTAAATTAAATGTAACAAA
TGTAAGAGAGGATTATATTGAGGAAGGACTTTTGGATATAATTCAAGAGATTATAAAAATGTCTTAA

Upstream 100 bases:

>100_bases
ACTCTAGAGTATAATTATATGTTAGTAGATTACTAGTTGTGGTACAATAAGAATAAAAGCTATCTATACCGGTACAGGTT
TTATATAGAGGTGAAAATGT

Downstream 100 bases:

>100_bases
ATACCCTTATAGAATTAAGTCCATAAGTTATGAGGTCTATATTTTATATTTAAATAATAGGAACTGCTAAAGCAGTTCCT
ATTATTTATATGTTCTATAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MYKYLEILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVRRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNEIFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKTESIKFFYTMPRFHNPLGTSYSQREKEAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIRTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYINFNGKINRERLIDRLKKK
SIIVATERGHYLSTFSREKILKLNVTNVREDYIEEGLLDIIQEIIKMS

Sequences:

>Translated_448_residues
MYKYLEILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVRRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNEIFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKTESIKFFYTMPRFHNPLGTSYSQREKEAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIRTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYINFNGKINRERLIDRLKKK
SIIVATERGHYLSTFSREKILKLNVTNVREDYIEEGLLDIIQEIIKMS
>Mature_448_residues
MYKYLEILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVRRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNEIFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKTESIKFFYTMPRFHNPLGTSYSQREKEAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIRTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYINFNGKINRERLIDRLKKK
SIIVATERGHYLSTFSREKILKLNVTNVREDYIEEGLLDIIQEIIKMS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=400, Percent_Identity=22.25, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33469970, Length=400, Percent_Identity=22.25, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1787710, Length=389, Percent_Identity=26.7352185089974, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790797, Length=374, Percent_Identity=24.5989304812834, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321236, Length=329, Percent_Identity=26.1398176291793, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356535, Length=245, Percent_Identity=27.3469387755102, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52152; Mature: 52152

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYLEILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECC
KSGYYVVRRKNPTNSNKEVLLDFASSAPDPQVFPYLDFQHCINEAIDIYKNEIFIYGTPK
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
GLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTTLTFPNKKETILIEQPSYHLF
CCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
IDYLETHNVPVLGIKRTDKGIDLNELERLFKTESIKFFYTMPRFHNPLGTSYSQREKEAI
EEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHH
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIP
HHHHHHCCEEEECCCHHHCCCCCCCCCCEEEECCCCEEEEEECCCHHHCCCHHHHHHHHH
NTILESFGKYKRLIDVDSSMLSQGALEIYIKSGMFQRHKQKIRTSYSLRSKCLDSILQKQ
HHHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKIYSDVFQYNPIKNPCIHTYINFNGKINRERLIDRLKKKSIIVATERGHYLSTFSREKI
HHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCCHHHHCCCCE
LKLNVTNVREDYIEEGLLDIIQEIIKMS
EEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKYLEILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECC
KSGYYVVRRKNPTNSNKEVLLDFASSAPDPQVFPYLDFQHCINEAIDIYKNEIFIYGTPK
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
GLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTTLTFPNKKETILIEQPSYHLF
CCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
IDYLETHNVPVLGIKRTDKGIDLNELERLFKTESIKFFYTMPRFHNPLGTSYSQREKEAI
EEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHH
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIP
HHHHHHCCEEEECCCHHHCCCCCCCCCCEEEECCCCEEEEEECCCHHHCCCHHHHHHHHH
NTILESFGKYKRLIDVDSSMLSQGALEIYIKSGMFQRHKQKIRTSYSLRSKCLDSILQKQ
HHHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKIYSDVFQYNPIKNPCIHTYINFNGKINRERLIDRLKKKSIIVATERGHYLSTFSREKI
HHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCCHHHHCCCCE
LKLNVTNVREDYIEEGLLDIIQEIIKMS
EEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]