Click here to switch to the map view.

The map label for this gene is nrnA [H]

Identifier: 153934519

GI number: 153934519

Start: 2391515

End: 2392477

Strand: Reverse

Name: nrnA [H]

Synonym: CLC_2263

Alternate gene names: 153934519

Gene position: 2392477-2391515 (Counterclockwise)

Preceding gene: 153935306

Following gene: 153937079

Centisome position: 63.62

GC content: 30.11

Gene sequence:

>963_bases
ATGATAACTAATGATATACTAGATAAAATAAAGGAAAGTAATAGTGTAGCTATTACTTTCCATACTTCTCCTGATGGGGA
TTCCTTAGGAAGCGCTTTAGGATTACTTCAGGGTATAAGAAAACTTAGCAAAAAAGCTTATATAATTTCCAAAGAACCTA
TACCAGAAACTTTTAAATATTTGCCCTGTAGTGAAGAAATCACAGGGGAGATAAAAAGGCCTATAGAAGGTACAGAGTGT
GTTATAGTTTTAGATTGTGGAAATGTAGAAAGAATAAATGCAGAATTAGACTTAGAAAATAGAGAATACTCCCTAATAAA
TATAGATCATCACTTATCTAACGATATGTATGGTGATTTAAATTTTGTAGACACAAATGCTCCAGCAGTGGCTGAGGTTG
TATATCAATTGCTAAAAATATTAGAGATAAATTCAGATAAAGATATAGCAGCTTGTTTATACACATCTTTAATTACAGAT
ACAGGTTCTTTTAGATATCCAGGTACTACATCTGTAACTCATATGATAGCAGGAGATTTAATAAACACAGGTCTAGATTT
TAGCTCAATACATAGAAAAATATTTGAAAATAAAAAATTTGAAAGATTAAAGCTTTATGGAAAAGTTTTAGAAGAAATGT
ATTTAGAAAATGAGAAGTTATGCGTTATGAAAGTAACAGAAAAAATGTTAAAAGAGTTGAACATAGAGGATGCAAAGGAT
ACATCAGATATTATATCACAAGGTATGCAAATAGGATCTGTAGAAGTGGCTGTATTATTTAAAGAAGTGGAAGAGGGAGT
AAAGATAAGTTTAAGATCAAAAGAATATGTGGATGTAAGAAAGATAGCTGAAAACTTTGGCGGTGGAGGACATATTCGTG
CTTCAGGAGCCTTTATAAAAGGAGAGGCTTTAAATATAGTAGAAAAAAAATTAATAGAAACTATAAAAAAAGAGTTGATA
TAA

Upstream 100 bases:

>100_bases
TTAAGAAATACACCAGAGGTTATAATAGAAGTAGATAATAGTATTGAAAGAGGTATGCATATAGATGAACTTCTTCATTC
AATAAAGGAGAATGAGTCAA

Downstream 100 bases:

>100_bases
ATGGATGGAGTAATAAATGTTTTAAAACCAAAGGGGATAACATCCTTTGATGTAGTTAGAGACATAAGAAAAATAGCGAA
AATAAAAAAAGTCGGTCATA

Product: DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MITNDILDKIKESNSVAITFHTSPDGDSLGSALGLLQGIRKLSKKAYIISKEPIPETFKYLPCSEEITGEIKRPIEGTEC
VIVLDCGNVERINAELDLENREYSLINIDHHLSNDMYGDLNFVDTNAPAVAEVVYQLLKILEINSDKDIAACLYTSLITD
TGSFRYPGTTSVTHMIAGDLINTGLDFSSIHRKIFENKKFERLKLYGKVLEEMYLENEKLCVMKVTEKMLKELNIEDAKD
TSDIISQGMQIGSVEVAVLFKEVEEGVKISLRSKEYVDVRKIAENFGGGGHIRASGAFIKGEALNIVEKKLIETIKKELI

Sequences:

>Translated_320_residues
MITNDILDKIKESNSVAITFHTSPDGDSLGSALGLLQGIRKLSKKAYIISKEPIPETFKYLPCSEEITGEIKRPIEGTEC
VIVLDCGNVERINAELDLENREYSLINIDHHLSNDMYGDLNFVDTNAPAVAEVVYQLLKILEINSDKDIAACLYTSLITD
TGSFRYPGTTSVTHMIAGDLINTGLDFSSIHRKIFENKKFERLKLYGKVLEEMYLENEKLCVMKVTEKMLKELNIEDAKD
TSDIISQGMQIGSVEVAVLFKEVEEGVKISLRSKEYVDVRKIAENFGGGGHIRASGAFIKGEALNIVEKKLIETIKKELI
>Mature_320_residues
MITNDILDKIKESNSVAITFHTSPDGDSLGSALGLLQGIRKLSKKAYIISKEPIPETFKYLPCSEEITGEIKRPIEGTEC
VIVLDCGNVERINAELDLENREYSLINIDHHLSNDMYGDLNFVDTNAPAVAEVVYQLLKILEINSDKDIAACLYTSLITD
TGSFRYPGTTSVTHMIAGDLINTGLDFSSIHRKIFENKKFERLKLYGKVLEEMYLENEKLCVMKVTEKMLKELNIEDAKD
TSDIISQGMQIGSVEVAVLFKEVEEGVKISLRSKEYVDVRKIAENFGGGGHIRASGAFIKGEALNIVEKKLIETIKKELI

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35715; Mature: 35715

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITNDILDKIKESNSVAITFHTSPDGDSLGSALGLLQGIRKLSKKAYIISKEPIPETFKY
CCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHC
LPCSEEITGEIKRPIEGTECVIVLDCGNVERINAELDLENREYSLINIDHHLSNDMYGDL
CCCCHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEEEEHHHHCCCCCCCC
NFVDTNAPAVAEVVYQLLKILEINSDKDIAACLYTSLITDTGSFRYPGTTSVTHMIAGDL
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
INTGLDFSSIHRKIFENKKFERLKLYGKVLEEMYLENEKLCVMKVTEKMLKELNIEDAKD
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCC
TSDIISQGMQIGSVEVAVLFKEVEEGVKISLRSKEYVDVRKIAENFGGGGHIRASGAFIK
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCEEE
GEALNIVEKKLIETIKKELI
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITNDILDKIKESNSVAITFHTSPDGDSLGSALGLLQGIRKLSKKAYIISKEPIPETFKY
CCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHC
LPCSEEITGEIKRPIEGTECVIVLDCGNVERINAELDLENREYSLINIDHHLSNDMYGDL
CCCCHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCCCEEEEEEHHHHCCCCCCCC
NFVDTNAPAVAEVVYQLLKILEINSDKDIAACLYTSLITDTGSFRYPGTTSVTHMIAGDL
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
INTGLDFSSIHRKIFENKKFERLKLYGKVLEEMYLENEKLCVMKVTEKMLKELNIEDAKD
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCC
TSDIISQGMQIGSVEVAVLFKEVEEGVKISLRSKEYVDVRKIAENFGGGGHIRASGAFIK
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCEEE
GEALNIVEKKLIETIKKELI
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]