Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 89257010

GI number: 89257010

Start: 1671668

End: 1672678

Strand: Reverse

Name: gcp [H]

Synonym: FTL_1741

Alternate gene names: 89257010

Gene position: 1672678-1671668 (Counterclockwise)

Preceding gene: 89257011

Following gene: 89257009

Centisome position: 88.22

GC content: 35.41

Gene sequence:

>1011_bases
ATGATAGTACTTGGTATTGAGAGCTCCTGTGATGAAACAGGTTTAGCGATATATGATTATTCAAAAAAGAAATTAATTGC
AGATGAATTATATAGCCAAGTCAAATTGCATAAGAAGTATGGTGGTGTTGTACCGGAACTTGCCTCGCGTGAGCATATCG
CTAAGCTTAATCTTTTAGCTAAGAAAATATTCAAAGAAACTGGTCTTAGCTTTGAAGATATTGATTGTATAGCATATACC
GCGATGCCTGGTTTAGTTGGTGCATTGATGGTTGGAGCTACATTTGCCAAAACACTAGGCTTAATCCATAATATTGATAC
AATTGCAGTTCATCACCTTGAGGGTCATCTTTTATCACCATTATTGGATCACAATAGTAATATAGAATATCCTTTCGTAG
CCTTGCTAGTTTCTGGAGGACATACACAACTATTTGAGGTAAAAGAGTTTGGTGAGTATAGTTTACTAGGGGAATCAATT
GATGATGCAGCAGGTGAGGCATTTGATAAGACGACTAAGCTTTTAGGTATGGGTTATCCTGGTGGAGTTGAGGTGGCAAA
TTTAGCTGATCAAGCTACTGATAAGTCTAAGTATATTCTACCAAGGCCGATGAAAAATAAACCTAATTTAGATTTTAGCT
TTAGTGGTTTAAAAACTGCTGTGCTAAATACATGGTATGATGAGCAAGATCAGTCATTAGAGAATAAGGCAAATCTATGC
TACGCATTCCAAAATGCGGCTATAGATGTATTGGTTTCTAAATGTGCTAAAGCATTACAAAAAACTAAAAATACAAGATT
GGTTATTTCAGGCGGAGTCAGTGCAAATAAACTATTGCGTCATCAGCTAGATTTATTGGCTAAAAATAGAGAATATCAAA
TATTTTTTCCTCCAATGAAATATTGTACAGATAATGGTGCAATGATTGCTCTAGCGGGAGCATATAGGTATGTAAATGGT
TTTAAGGACTCTAATTTAGAGATTAATGTTAAAGCAAGATCACCACTCTAG

Upstream 100 bases:

>100_bases
TTGTCTTAATGTCTATATCTTTTGTTTTAGGCTTATTGCTTGGTTCTTTTATAACTAAGTTTATTCAGATAACTAAAACA
AGTGGTGGCGCTAAAAAGTA

Downstream 100 bases:

>100_bases
CATTTATATCAAAGTACTATCAAAAAAATCATCAATGTGCTATCATTAAGTTGTAATAAATTTCCACATCCACATAAAGT
GGGTCAATTCAAAAAGGGTT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQNAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNREYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL

Sequences:

>Translated_336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQNAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNREYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL
>Mature_336_residues
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYT
AMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESI
DDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
YAFQNAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNREYQIFFPPMKYCTDNGAMIALAGAYRYVNG
FKDSNLEINVKARSPL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=344, Percent_Identity=32.5581395348837, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI8923380, Length=324, Percent_Identity=29.0123456790123, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=54.7619047619048, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=30.6060606060606, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=27.82874617737, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=360, Percent_Identity=32.5, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322891, Length=354, Percent_Identity=26.5536723163842, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129063, Length=336, Percent_Identity=33.6309523809524, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI21357207, Length=335, Percent_Identity=30.1492537313433, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36931; Mature: 36931

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHH
KKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHH
LLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYP
HHCCCCCCCCCEEEEEEECCCCEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
CCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHEE
YAFQNAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNREYQIFFPPMK
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHH
YCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
HHCCCCCEEEEEHHHHHHCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLA
CEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHH
KKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHH
LLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYP
HHCCCCCCCCCEEEEEEECCCCEEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLC
CCCHHHHHHHHCCCCCCEECCCCCCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHEE
YAFQNAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNREYQIFFPPMK
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHH
YCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
HHCCCCCEEEEEHHHHHHCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA