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The map label for this gene is hemA [H]

Identifier: 89256991

GI number: 89256991

Start: 1652790

End: 1654034

Strand: Reverse

Name: hemA [H]

Synonym: FTL_1722

Alternate gene names: 89256991

Gene position: 1654034-1652790 (Counterclockwise)

Preceding gene: 89256996

Following gene: 89256990

Centisome position: 87.24

GC content: 32.69

Gene sequence:

>1245_bases
ATGGCGTTAATATCTTTAGCAATTGATTATAAAAAGTCTCCGATAGAAGTTCGTAGTGAGTTTGCACTCTCTGGTTTAGA
TGTATCTATGCTATATAGATCAATACTTGCTATAGATAATGTTGTACATGCTGTAATCTTATCAACTTGTAATCGTACAG
AAGTATATCTTGAGATATCTGATCTAAGAGTAGTTGATGATATTTTAGTATGGTGGCAAGGCTATGTTAGAAACCCTAAT
TATAAAATAAAAGATTATTTTAAGCTAAGACAAGGTACAGAAGTAATTATGCACCTTATGAAATTGGCTTGTGGTTTAGA
ATCGATGGTTTTAGGTGAACCGCAAATATTAGGACAAGTAAAAGATTCTTATACTCTCAGTAAAAAAAATCATGCTATTG
GTAAAGAACTAGATAGGGTTTTTCAGAAGGTTTTTGCAACTGCTAAAAGAGTACGTAGTGAAACTAGAATTGGTTATTGC
CCAGTTTCAGTTGCATTCTCAGCAATTACTTTGGCTAAAAGGCAACTAGATAATATTTCTAGTAAGAATGTCCTTATTAT
TGGTGCTGGTCAAACAGGAGAGCTTTTGTTTCGTCATGTTACAGCACTTGCTCCTAAGCAGATAATGCTAGCAAACCGAA
CTATCGAGAAAGCACAGAAAATTACTTCTGTTTTTAGAAATGCTAGTGCTCATTACTTATCAGAGCTACCGCAATTGATC
AAAAAAGCTGATATTATAATTGCTGCAGTCAATGTTTTAGAATACATTGTCACATGCAAATATGTTGGCGATAAACCTAG
AGTTTTTATTGATATATCAATACCTCAAGCTTTAGACCCTAAATTAGGCGAGTTAGAGCAAAATGTTTATTATTGCGTTG
ATGATATTAACGCTGTTATTGAAGATAACAAAGATAAAAGAAAGTATGAAAGCTCTAAAGCACAGAAAATTATTGTAAAA
TCTCTTGAGGAATATCTTGAAAAAGAAAAGGCTATTATCTCAAATAGTGCGATTAAAGAGCTTTTCCAAAAAGCTGACGG
TTTAGTTGATTTATCGCTAGAGAAAAGCTTAGCTAAGATAAGAAATGGTAAAGATGCCGAAGAGATAATTAAAAGATTTG
CTTATGAAATTAAAAAGAAAGTTTTACACTATCCTGTTGTAGGAATGAAAGAGGCTTCCAAGCAGGGTAGAAGTGACTGT
CTTGTATGTATGAAACGTATGTTTGGTTTAAATGTGGAAAAATAA

Upstream 100 bases:

>100_bases
TATTAATCAGATTAGAATGTAATGTCTTAGTCTTTTGTGTTAAAATATGTTTTTGTTTTTCTAGGTTAATTTATTTTATT
ACATTTAATAATATTTGAAT

Downstream 100 bases:

>100_bases
ATGAAAGATTCTATTAAAGCAAAATTGCAAAGTTTAATAGAAAGGCATGAGGAAGTTAGTGCCTTATTAAGTGAGGCAGG
AATTATCTCTGATCAAAATA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLRVVDDILVWWQGYVRNPN
YKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYC
PVSVAFSAITLAKRQLDNISSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLI
KKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVK
SLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKIRNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDC
LVCMKRMFGLNVEK

Sequences:

>Translated_414_residues
MALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLRVVDDILVWWQGYVRNPN
YKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYC
PVSVAFSAITLAKRQLDNISSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLI
KKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVK
SLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKIRNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDC
LVCMKRMFGLNVEK
>Mature_413_residues
ALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLRVVDDILVWWQGYVRNPNY
KIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYCP
VSVAFSAITLAKRQLDNISSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLIK
KADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVKS
LEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKIRNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDCL
VCMKRMFGLNVEK

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=418, Percent_Identity=33.7320574162679, Blast_Score=244, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 46785; Mature: 46654

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEIS
CCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
DLRVVDDILVWWQGYVRNPNYKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHCCCHHHHHHH
KDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYCPVSVAFSAITLAKRQLDNIS
HHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
SKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLI
CCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHEEHHHHHHHHH
EDNKDKRKYESSKAQKIIVKSLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
RNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDCLVCMKRMFGLNVEK
HCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEIS
CEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
DLRVVDDILVWWQGYVRNPNYKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHCCCHHHHHHH
KDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYCPVSVAFSAITLAKRQLDNIS
HHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
SKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLI
CCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHEEHHHHHHHHH
EDNKDKRKYESSKAQKIIVKSLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
RNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDCLVCMKRMFGLNVEK
HCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA