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The map label for this gene is rlmH

Identifier: 89256988

GI number: 89256988

Start: 1650366

End: 1650866

Strand: Direct

Name: rlmH

Synonym: FTL_1719

Alternate gene names: 89256988

Gene position: 1650366-1650866 (Clockwise)

Preceding gene: 89256987

Following gene: 89256992

Centisome position: 87.04

GC content: 30.94

Gene sequence:

>501_bases
ATGATGGCATTTTTATTAGACATTATAACATTTCTACAAATATCTTTTTCTACAAATATCTTTCGGATTAACTATAAATG
GGTTAGTGATGGCTATGATGAATACAAGAAACGTTTAAGTAAATTAATACCGCTTGAATTAATCGAACTGCCAATAGCTA
AACGCACCAAAACTGGTAATCCTAAGCTTTGGATGGAGCAAGAAGCTAAAACAATTCTTGGTAAGCTCAATGATTCTGAT
CATTTAGTTATACTTGATGTTAATTCAAAAATCATTTCTACAGAAGAATTAGCCGATAAAATGCAAAATTGGAAATTTAA
TAATCCAAACGTTGTGATTTTAATTGGTGGCCCTGATGGCATAGATCAAAGTATCAAGGATATAGCTAAAGAAAAAATAT
CTATCTCAAAAATGACATTCCCTCATCCTTTAGTACGTATTATTGCTGAACAGCTATATAGAGCTTACACAATATTAGAG
GGTCATCCTTATCATAAATAG

Upstream 100 bases:

>100_bases
ACAACTGTACGCTTATCTATGTTAAAAAACTTACTCAGCTCGAACTCCGTCATACCTTCTTCATATTTATTAATTACGAT
GTCTCTAAAATCTTGGCTAT

Downstream 100 bases:

>100_bases
CCAAGTTGTGCCTTAGTACATCTATCGTTATTATTTAAATCTTTAACTATTTTAATATCATTAAAATTACACTGAGAAAA
TAAAGCTGTAATAGCATCTG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGNPKLWMEQEAKTILGKLNDSD
HLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDGIDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILE
GHPYHK

Sequences:

>Translated_166_residues
MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGNPKLWMEQEAKTILGKLNDSD
HLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDGIDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILE
GHPYHK
>Mature_166_residues
MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGNPKLWMEQEAKTILGKLNDSD
HLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDGIDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILE
GHPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=141, Percent_Identity=40.4255319148936, Blast_Score=120, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_FRATF (A7NE94)

Other databases:

- EMBL:   CP000803
- RefSeq:   YP_001429253.2
- ProteinModelPortal:   A7NE94
- SMR:   A7NE94
- STRING:   A7NE94
- GeneID:   5522729
- GenomeReviews:   CP000803_GR
- KEGG:   fta:FTA_1823
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- ProtClustDB:   CLSK986414
- BioCyc:   FTUL458234:FTA_1823-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 19188; Mature: 19188

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGN
CHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
PKLWMEQEAKTILGKLNDSDHLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDG
CCEEEHHHHHHHHHCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCCCEEEEECCCCC
IDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILEGHPYHK
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGN
CHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCC
PKLWMEQEAKTILGKLNDSDHLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDG
CCEEEHHHHHHHHHCCCCCCCEEEEECCCCEECHHHHHHHHHCCCCCCCCEEEEECCCCC
IDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILEGHPYHK
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA