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The map label for this gene is mlaA [H]

Identifier: 89256914

GI number: 89256914

Start: 1568349

End: 1569383

Strand: Reverse

Name: mlaA [H]

Synonym: FTL_1637

Alternate gene names: 89256914

Gene position: 1569383-1568349 (Counterclockwise)

Preceding gene: 89256919

Following gene: 89256911

Centisome position: 82.77

GC content: 35.36

Gene sequence:

>1035_bases
ATGAGAATAATTTTGATGAAACTAAATGCTAAGTCTACTTTGCTATTATCAATGTTAGGTGTGACTTTGAGTAGCTGCTC
AAGTTTGAAAGCTACAAAAGATAATCGCGATCCTTTTGAGAGTTACAATAGAAAAATGTATGCTTTTAATGATAAGGCTT
ATGAAACTTTAACTCCAGCTGCTAATTCGTATGAAAAAGTTGTTCCAGATACTTTAAAGAGCGGTATTTTTAATATTTTC
CAAAACTTGGCTGAGCCTGCTAGAGTTGCAAATGATATGTTCCAAGGTGAATGGGATTATGCTGGGGATGATGGTTTTAG
ATTCTTGACAAATACTACTTTAGGTTTGGCAGGTTACTTTGATGTCGCGGATAGTTGGTTTAACAAACCTATGAGATATC
ATCAAAGTTTTGCAGTTACTCTTCATAAATGGGGTGTGTATAAGGATAATGAAGCCTCTCCTTATGTGGTATGGCCGTTA
ATTGGCCCAGGCACATTAGAGGATATTACTACAGGTGTTGATGCGTTGTTTAATCCATTAACTTATATATTCTTCTTTGC
TCCAGTTGGTTCGGCAATATCTTGGGGAGTAAGTGTTGGTACGACAGGTGCATATTATGTTAACCAAGGAGTATCATATC
TACCATCATATTCAAATCTTAAAGAAGTTTCTATTGATCCTTACATAGCGATGAGAAATGCTTATTTACAAAATTATGAC
TATGGTATGGCTAAAGTATTAAAACAACAGTTAAGCAAAGATGATGCAACTATTCAGACCGATCAAGCTGTATTAAGAAT
ACTAGGATTAGATAGTGATAACGTCAATGCGCAAATTGCTACTACAGGCGGTACTAAGGTCAAGTCTTCTGAGCCTCCTG
TTATATTCAAAAGTAATATTAGTACCGTTAACAAAGCATCACAAGTTGAGGAAGCATTTGATAAGGATTACTCAAATGAT
AGTACAGCTCTTGATTTGGCTAATGTTGATAATGACGATACAACACAGAGTGAAGCTAGCAAGCTAAAGAAATAA

Upstream 100 bases:

>100_bases
TTCTAAATAATATCAAAGATGAATCTCTAAGAAAATTTTTATTAGTGTTTTGTATACTAATTTACTATAATAAGACTTGT
ATTTTTTTGCCAATCTTAAT

Downstream 100 bases:

>100_bases
GAGATGCCAAAGCAGATCTTCCAGGTGATGCAGACTCTCCAGCATCAGCAGTTCAAACTCTTGCCGAGCAGGGGTAGTTT
AAGTTTAGTTTTCTATATAA

Product: lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRIILMKLNAKSTLLLSMLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIF
QNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPL
IGPGTLEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYD
YGMAKVLKQQLSKDDATIQTDQAVLRILGLDSDNVNAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDKDYSND
STALDLANVDNDDTTQSEASKLKK

Sequences:

>Translated_344_residues
MRIILMKLNAKSTLLLSMLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIF
QNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPL
IGPGTLEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYD
YGMAKVLKQQLSKDDATIQTDQAVLRILGLDSDNVNAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDKDYSND
STALDLANVDNDDTTQSEASKLKK
>Mature_344_residues
MRIILMKLNAKSTLLLSMLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPAANSYEKVVPDTLKSGIFNIF
QNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYFDVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPL
IGPGTLEDITTGVDALFNPLTYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYD
YGMAKVLKQQLSKDDATIQTDQAVLRILGLDSDNVNAQIATTGGTKVKSSEPPVIFKSNISTVNKASQVEEAFDKDYSND
STALDLANVDNDDTTQSEASKLKK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=262, Percent_Identity=33.969465648855, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 38092; Mature: 38092

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILMKLNAKSTLLLSMLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPA
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEECCCHHHHHCCC
ANSYEKVVPDTLKSGIFNIFQNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHH
DVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGTLEDITTGVDALFNPL
HHHHHHHCCHHHHHHHHEEEEECCCCEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
TYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYD
HHHHHHHHHCCHHHCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
YGMAKVLKQQLSKDDATIQTDQAVLRILGLDSDNVNAQIATTGGTKVKSSEPPVIFKSNI
HHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEECCC
STVNKASQVEEAFDKDYSNDSTALDLANVDNDDTTQSEASKLKK
CHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MRIILMKLNAKSTLLLSMLGVTLSSCSSLKATKDNRDPFESYNRKMYAFNDKAYETLTPA
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEECCCHHHHHCCC
ANSYEKVVPDTLKSGIFNIFQNLAEPARVANDMFQGEWDYAGDDGFRFLTNTTLGLAGYF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHH
DVADSWFNKPMRYHQSFAVTLHKWGVYKDNEASPYVVWPLIGPGTLEDITTGVDALFNPL
HHHHHHHCCHHHHHHHHEEEEECCCCEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
TYIFFFAPVGSAISWGVSVGTTGAYYVNQGVSYLPSYSNLKEVSIDPYIAMRNAYLQNYD
HHHHHHHHHCCHHHCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
YGMAKVLKQQLSKDDATIQTDQAVLRILGLDSDNVNAQIATTGGTKVKSSEPPVIFKSNI
HHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEECCC
STVNKASQVEEAFDKDYSNDSTALDLANVDNDDTTQSEASKLKK
CHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]