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The map label for this gene is sdaC [H]

Identifier: 89256809

GI number: 89256809

Start: 1454461

End: 1455723

Strand: Direct

Name: sdaC [H]

Synonym: FTL_1524

Alternate gene names: 89256809

Gene position: 1454461-1455723 (Clockwise)

Preceding gene: 89256808

Following gene: 89256827

Centisome position: 76.71

GC content: 27.47

Gene sequence:

>1263_bases
ATGAAAAAACCAGATTACTCAAATACTACAAAAGTCGATATCCAGTGGGTATTTACGTTATTTGGTACTGCAATAGGTGC
AGGGTTACTTTATCTACCTGTTCAAGCAGGGGATAGCGGCCTTTGGGCTTTAGTAACAGTACTTATTTTTGCTTTACCTT
TAACGTATTACTCACATAAAAATATGTCAAATATTGTACTTTGCACAGATAATGGTGGTATTACAGATGTATTTACCCAC
AATCTTGGTAGATTTTTTGGTTTAACCTGCGTAGTGCTATATTTCTTTGCAATATTCCTAAATATGCCAATGTACTCTAT
TGGTCTAAATAGCGAACTAAGTAATTTTCTTTTAAACTACAATATTGTAAAAACCAATTTATCAACACATATATGGTTTA
GTTTTAGTATTTTAGCCCTTTTATTAATAATAGTTTCTTTAGGTATCAATATAATTCTAAAGTTTATGCAGCTTATAGTT
ATATTATTGATTATATTAGTAGTGACACTGTCCATATATATAATACCTTATTGGAACTTTGAGTTTATAACTGATAGTCA
TTTTGATACTGTTGGTTATATTACAGGTGTATTAATGGTATTACCAATCTTGATATTATCGATGAATCACTCACCTGTTA
TTTCTAGTCTAGTAATTTTTTATCGTGATTATGTAAAAGTTGAGCGATCACAAGAAAAATATAAAGTTTATAAAATACTT
AAAATTAATGCTCTAATTCTTTTTATCTTTGTACTGCTTTTTGTAACATCTTGCCTACTTAGCACTACTATACCAGACCT
TAATAGGGCTAATGCAAATAATCTAACAATAGTAACTCTAATACAAGAGCAGCATCATAGTACTTTATTGAATATTTTAG
CACCAATGATAGTTTTCACTGCTATTATTAGTTCATTTATAGGCTGTTACATAGGTTCAAAAGAAGCTTTGAAATATCTA
TTTAAATATTTCTTTAAAAATATTTATAAAATAGAATTTTCTGATTCATTAATAAATAAAATCTGTGTTGGGCTAATATT
TATAGTTCTCTGGATATGCACAATATGTAATTTTAAAATCCTTAATATTATAGGCATATTAGTTGCGCCTACTGTGGCTT
TTCTACTATATGTTTTACCTGTAATAATAATTTACAAAAATATCCAATGTAAAGATTATAGACGCGTAATATTAGACTCT
ATTTTATTTATAATGGGATTAATAATTATATTTGGCTATGTAATTGGTTTACTTCTAAAATAA

Upstream 100 bases:

>100_bases
ATCATCACACATCGACTTCATATTGATGAGTTTCAAAAAGGATTTGAAATAATGAAAAGTGGTCAATGTGGTAAAGTAAT
ACTGGATTGGAGCAGCTAGA

Downstream 100 bases:

>100_bases
CGACTTAACCTAACTGCCAATTAGCATATTCTAAATCATCTTTAGTTGTAATCTTAATATTTTTCTTTGAACATTCAACA
ACAATCGGATTTATACCAAA

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKPDYSNTTKVDIQWVFTLFGTAIGAGLLYLPVQAGDSGLWALVTVLIFALPLTYYSHKNMSNIVLCTDNGGITDVFTH
NLGRFFGLTCVVLYFFAIFLNMPMYSIGLNSELSNFLLNYNIVKTNLSTHIWFSFSILALLLIIVSLGINIILKFMQLIV
ILLIILVVTLSIYIIPYWNFEFITDSHFDTVGYITGVLMVLPILILSMNHSPVISSLVIFYRDYVKVERSQEKYKVYKIL
KINALILFIFVLLFVTSCLLSTTIPDLNRANANNLTIVTLIQEQHHSTLLNILAPMIVFTAIISSFIGCYIGSKEALKYL
FKYFFKNIYKIEFSDSLINKICVGLIFIVLWICTICNFKILNIIGILVAPTVAFLLYVLPVIIIYKNIQCKDYRRVILDS
ILFIMGLIIIFGYVIGLLLK

Sequences:

>Translated_420_residues
MKKPDYSNTTKVDIQWVFTLFGTAIGAGLLYLPVQAGDSGLWALVTVLIFALPLTYYSHKNMSNIVLCTDNGGITDVFTH
NLGRFFGLTCVVLYFFAIFLNMPMYSIGLNSELSNFLLNYNIVKTNLSTHIWFSFSILALLLIIVSLGINIILKFMQLIV
ILLIILVVTLSIYIIPYWNFEFITDSHFDTVGYITGVLMVLPILILSMNHSPVISSLVIFYRDYVKVERSQEKYKVYKIL
KINALILFIFVLLFVTSCLLSTTIPDLNRANANNLTIVTLIQEQHHSTLLNILAPMIVFTAIISSFIGCYIGSKEALKYL
FKYFFKNIYKIEFSDSLINKICVGLIFIVLWICTICNFKILNIIGILVAPTVAFLLYVLPVIIIYKNIQCKDYRRVILDS
ILFIMGLIIIFGYVIGLLLK
>Mature_420_residues
MKKPDYSNTTKVDIQWVFTLFGTAIGAGLLYLPVQAGDSGLWALVTVLIFALPLTYYSHKNMSNIVLCTDNGGITDVFTH
NLGRFFGLTCVVLYFFAIFLNMPMYSIGLNSELSNFLLNYNIVKTNLSTHIWFSFSILALLLIIVSLGINIILKFMQLIV
ILLIILVVTLSIYIIPYWNFEFITDSHFDTVGYITGVLMVLPILILSMNHSPVISSLVIFYRDYVKVERSQEKYKVYKIL
KINALILFIFVLLFVTSCLLSTTIPDLNRANANNLTIVTLIQEQHHSTLLNILAPMIVFTAIISSFIGCYIGSKEALKYL
FKYFFKNIYKIEFSDSLINKICVGLIFIVLWICTICNFKILNIIGILVAPTVAFLLYVLPVIIIYKNIQCKDYRRVILDS
ILFIMGLIIIFGYVIGLLLK

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=417, Percent_Identity=30.6954436450839, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789504, Length=429, Percent_Identity=27.2727272727273, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789211, Length=391, Percent_Identity=26.8542199488491, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789961, Length=392, Percent_Identity=25.5102040816327, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693183, Length=418, Percent_Identity=21.0526315789474, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 47740; Mature: 47740

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPDYSNTTKVDIQWVFTLFGTAIGAGLLYLPVQAGDSGLWALVTVLIFALPLTYYSHK
CCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NMSNIVLCTDNGGITDVFTHNLGRFFGLTCVVLYFFAIFLNMPMYSIGLNSELSNFLLNY
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHC
NIVKTNLSTHIWFSFSILALLLIIVSLGINIILKFMQLIVILLIILVVTLSIYIIPYWNF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
EFITDSHFDTVGYITGVLMVLPILILSMNHSPVISSLVIFYRDYVKVERSQEKYKVYKIL
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINALILFIFVLLFVTSCLLSTTIPDLNRANANNLTIVTLIQEQHHSTLLNILAPMIVFT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
AIISSFIGCYIGSKEALKYLFKYFFKNIYKIEFSDSLINKICVGLIFIVLWICTICNFKI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHH
LNIIGILVAPTVAFLLYVLPVIIIYKNIQCKDYRRVILDSILFIMGLIIIFGYVIGLLLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKPDYSNTTKVDIQWVFTLFGTAIGAGLLYLPVQAGDSGLWALVTVLIFALPLTYYSHK
CCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NMSNIVLCTDNGGITDVFTHNLGRFFGLTCVVLYFFAIFLNMPMYSIGLNSELSNFLLNY
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHC
NIVKTNLSTHIWFSFSILALLLIIVSLGINIILKFMQLIVILLIILVVTLSIYIIPYWNF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
EFITDSHFDTVGYITGVLMVLPILILSMNHSPVISSLVIFYRDYVKVERSQEKYKVYKIL
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KINALILFIFVLLFVTSCLLSTTIPDLNRANANNLTIVTLIQEQHHSTLLNILAPMIVFT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
AIISSFIGCYIGSKEALKYLFKYFFKNIYKIEFSDSLINKICVGLIFIVLWICTICNFKI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHH
LNIIGILVAPTVAFLLYVLPVIIIYKNIQCKDYRRVILDSILFIMGLIIIFGYVIGLLLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]