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The map label for this gene is hmp [H]

Identifier: 57238599

GI number: 57238599

Start: 1658732

End: 1659154

Strand: Direct

Name: hmp [H]

Synonym: CJE1757

Alternate gene names: 57238599

Gene position: 1658732-1659154 (Clockwise)

Preceding gene: 57238577

Following gene: 57238601

Centisome position: 93.3

GC content: 28.61

Gene sequence:

>423_bases
ATGACAAAAGAACAAATTCAAATCATCAAAGATTGTGTGCCTATTTTGCAAAAAAATGGAGAGGATTTAACCAATGAGTT
TTATAAAATAATGTTTAATGATTATCCTGAGGTAAAACCTATGTTTAATATGGAAAAACAAATTTCAGGAGAACAACCAA
AAGCTTTAGCAATGGCGATTTTAATGGCGGCTAAAAATATAGAAAATTTAGAAAATATGAGAAACTTTGTTGATAAAGTT
GCCATAACTCATGTTAATTTAGGAGTTAAAGAAGAGCATTATCCTATAGTTGGAGCTTGCCTTTTAAAGGCTATTAAAAA
TCTTTTAAATCCTGACGAAGCTACTCTTAAAGCTTGGGAAGTTGCTTATGGAAAAATTGCTAAATTTTATATCGATATAG
AAAAAAAGCTCTATGATAAATAA

Upstream 100 bases:

>100_bases
AATTTTAAATTTATATTTTTGAGCATAATTTTAACACAAGTCAATTTTTTTCTCCTTTTTAAGATATAAAATATCTCTTT
TACAACAAAAAGGAGAAACT

Downstream 100 bases:

>100_bases
TATAAGCCCATTTTGGGCTTTAATCAAATTTTTCTACTAAATTTTTAGCTAATTCCTTTATATTCTCACCCTTTAATTCG
CTGATTTCACCATTTTGAGC

Product: flavohemoprotein, truncation

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTKEQIQIIKDCVPILQKNGEDLTNEFYKIMFNDYPEVKPMFNMEKQISGEQPKALAMAILMAAKNIENLENMRNFVDKV
AITHVNLGVKEEHYPIVGACLLKAIKNLLNPDEATLKAWEVAYGKIAKFYIDIEKKLYDK

Sequences:

>Translated_140_residues
MTKEQIQIIKDCVPILQKNGEDLTNEFYKIMFNDYPEVKPMFNMEKQISGEQPKALAMAILMAAKNIENLENMRNFVDKV
AITHVNLGVKEEHYPIVGACLLKAIKNLLNPDEATLKAWEVAYGKIAKFYIDIEKKLYDK
>Mature_139_residues
TKEQIQIIKDCVPILQKNGEDLTNEFYKIMFNDYPEVKPMFNMEKQISGEQPKALAMAILMAAKNIENLENMRNFVDKVA
ITHVNLGVKEEHYPIVGACLLKAIKNLLNPDEATLKAWEVAYGKIAKFYIDIEKKLYDK

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=140, Percent_Identity=37.8571428571429, Blast_Score=102, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321673, Length=137, Percent_Identity=44.5255474452555, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 16109; Mature: 15978

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEQIQIIKDCVPILQKNGEDLTNEFYKIMFNDYPEVKPMFNMEKQISGEQPKALAMAI
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHCHHHHCCCCCHHHHHHHH
LMAAKNIENLENMRNFVDKVAITHVNLGVKEEHYPIVGACLLKAIKNLLNPDEATLKAWE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VAYGKIAKFYIDIEKKLYDK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKEQIQIIKDCVPILQKNGEDLTNEFYKIMFNDYPEVKPMFNMEKQISGEQPKALAMAI
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHCHHHHCCCCCHHHHHHHH
LMAAKNIENLENMRNFVDKVAITHVNLGVKEEHYPIVGACLLKAIKNLLNPDEATLKAWE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VAYGKIAKFYIDIEKKLYDK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]