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The map label for this gene is appC [H]

Identifier: 57238595

GI number: 57238595

Start: 1652440

End: 1653228

Strand: Reverse

Name: appC [H]

Synonym: CJE1753

Alternate gene names: 57238595

Gene position: 1653228-1652440 (Counterclockwise)

Preceding gene: 57238596

Following gene: 57238594

Centisome position: 92.99

GC content: 29.02

Gene sequence:

>789_bases
TTGTTTAAATTTCTTATCATTCTTGCGCCTTTAATTTTTTTGTTTTTATGCGCCTTGTTTGCACCTTTTTTGGCTCCTTT
TGATATTTTAAGCACTCATTTAGAAAATTTGCATCAAGCTCCTAATTTTACTTATATTTTAGGGACTGATTTTTTAGGCA
GAGATTTGTTTTCTCGTTTGCTTTTTGCTTTGAGAAATTCTTTGATTATAGGTGTTGGTGGATCTTTATTGTCTATTATC
TTTGCTTTGTACTATTTGTTTTTAGCGCGATGTTTTTTTTATGTTTTTTGGATGCGTATTTTAGAGTTTTTTTTAGCCTT
GCCTGCTTTTTTACTTATGATGTTTTTTCAAAGTATGATAACTTCTGATGTGTTTTTGATGATTTTTTTAATCGCTTTAA
TTCATTGGTGTTTCATAGCAAGAATTATAGAAAGTGAATTAAAAAGACTTGAAAATTTAGATTTTTACAAAGCAAATATA
GTGCTTGGAAGAACTAAATTTAGAGCTTTTTTTAAAGATTTAATACCTGCTTTAAAAACACTGATTTTTACACTTTTTAT
ATTTAATATCGTTCATGCTATAGCCACAGAAGCTACTTTGAGTTTTTTTGGACTGGGTTTAGGATTTGAAATTCCAACTT
TAGGTACTCTTTTGAGTGAGTCTTCAAAAGCAGTTTTTATAGGCGCTTGGTGGATGATACTTTTTCCACTTTTAAGCTTG
CTTTTGTTGTTTTTACCTCTTTTATGGTTGGGTAATTTTTTACAAAAAATTTGGGGTATAAGATCTTGA

Upstream 100 bases:

>100_bases
CTTGCACTTATATTTTTTAGCGTTTTGCTTGCAGCATTTTTTACATTTTTAAGTGATATTGTAGCTAGGATTTTAAATCC
TAGATTAAGAAGGCTTGATT

Downstream 100 bases:

>100_bases
AGGTAAGAAATTTAAATATCAGTTTGAAGAATAATTTATTGCTTAAGGATATTAATTTAGATATAAAAACAGGCAAAACT
TTAATGATACTAGGACAAAG

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MFKFLIILAPLIFLFLCALFAPFLAPFDILSTHLENLHQAPNFTYILGTDFLGRDLFSRLLFALRNSLIIGVGGSLLSII
FALYYLFLARCFFYVFWMRILEFFLALPAFLLMMFFQSMITSDVFLMIFLIALIHWCFIARIIESELKRLENLDFYKANI
VLGRTKFRAFFKDLIPALKTLIFTLFIFNIVHAIATEATLSFFGLGLGFEIPTLGTLLSESSKAVFIGAWWMILFPLLSL
LLLFLPLLWLGNFLQKIWGIRS

Sequences:

>Translated_262_residues
MFKFLIILAPLIFLFLCALFAPFLAPFDILSTHLENLHQAPNFTYILGTDFLGRDLFSRLLFALRNSLIIGVGGSLLSII
FALYYLFLARCFFYVFWMRILEFFLALPAFLLMMFFQSMITSDVFLMIFLIALIHWCFIARIIESELKRLENLDFYKANI
VLGRTKFRAFFKDLIPALKTLIFTLFIFNIVHAIATEATLSFFGLGLGFEIPTLGTLLSESSKAVFIGAWWMILFPLLSL
LLLFLPLLWLGNFLQKIWGIRS
>Mature_262_residues
MFKFLIILAPLIFLFLCALFAPFLAPFDILSTHLENLHQAPNFTYILGTDFLGRDLFSRLLFALRNSLIIGVGGSLLSII
FALYYLFLARCFFYVFWMRILEFFLALPAFLLMMFFQSMITSDVFLMIFLIALIHWCFIARIIESELKRLENLDFYKANI
VLGRTKFRAFFKDLIPALKTLIFTLFIFNIVHAIATEATLSFFGLGLGFEIPTLGTLLSESSKAVFIGAWWMILFPLLSL
LLLFLPLLWLGNFLQKIWGIRS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=255, Percent_Identity=28.2352941176471, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789889, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787760, Length=241, Percent_Identity=24.4813278008299, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788505, Length=219, Percent_Identity=23.2876712328767, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789964, Length=256, Percent_Identity=25.78125, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30283; Mature: 30283

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFLIILAPLIFLFLCALFAPFLAPFDILSTHLENLHQAPNFTYILGTDFLGRDLFSRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
LFALRNSLIIGVGGSLLSIIFALYYLFLARCFFYVFWMRILEFFLALPAFLLMMFFQSMI
HHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDVFLMIFLIALIHWCFIARIIESELKRLENLDFYKANIVLGRTKFRAFFKDLIPALKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFTLFIFNIVHAIATEATLSFFGLGLGFEIPTLGTLLSESSKAVFIGAWWMILFPLLSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LLLFLPLLWLGNFLQKIWGIRS
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFKFLIILAPLIFLFLCALFAPFLAPFDILSTHLENLHQAPNFTYILGTDFLGRDLFSRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
LFALRNSLIIGVGGSLLSIIFALYYLFLARCFFYVFWMRILEFFLALPAFLLMMFFQSMI
HHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDVFLMIFLIALIHWCFIARIIESELKRLENLDFYKANIVLGRTKFRAFFKDLIPALKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFTLFIFNIVHAIATEATLSFFGLGLGFEIPTLGTLLSESSKAVFIGAWWMILFPLLSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LLLFLPLLWLGNFLQKIWGIRS
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]