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The map label for this gene is nuoB [H]

Identifier: 57238591

GI number: 57238591

Start: 1650088

End: 1650591

Strand: Reverse

Name: nuoB [H]

Synonym: CJE1749

Alternate gene names: 57238591

Gene position: 1650591-1650088 (Counterclockwise)

Preceding gene: 57238592

Following gene: 57238590

Centisome position: 92.84

GC content: 38.1

Gene sequence:

>504_bases
ATGGCAGAGCATCAAATAAATTATGCAAGTGGTTTACCCGTAGTTTTAACTAGTGTTGATAAACTAGTTCAATGGGGTAG
GAGTAATTCTTTATGGGCTTTATCTTATGGACTTGCCTGTTGTGCGATTGAGATGATGGCGGCTGGGGGTTCAAGATATG
ATTTTGATAGATTTGGAACGATTTTTAGAGCTTCGCCACGCCATAGTGAAGTAATGATTATTGCAGGAACTTTATGTAAA
AAGCATGCTGAATTTACAAGAAGACTTTATGATCAAATGCCTGATCCTAAATGGGTGATTTCTATGGGAAGTTGTGCCAA
TACAGGCGGTATGTTTAATACTTATTCTACTGTTCAAGGAGTGGATAGAATTATACCTGTAGATATTTATGTGCCAGGCT
GTGCTCCACGCCCCGAAAGTTTTCAGTTTGCTTTGATGATTTTGCAAAAAAAGATCCGCAAAGAAAAAGCAAGTCGTAAA
ATCGCACCTAAAAGGTTGGTATAA

Upstream 100 bases:

>100_bases
TTTTTAAAGATTTAGGTTGGTTTGGACTTTTAGAAGTTTTTGTTTTTATCGTACTTTTAGGAGTTGGATTTTTATATGCT
TATAAAAAAGGAGCGTTTGC

Downstream 100 bases:

>100_bases
TGAGAAAGTATAGCGATAAAAAAAATGCTCAAACTCAAAATTACTACAAAGATAGATTTTATCACGCGCCACACACTGTA
AAATCTGATGTTAATGAAAG

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MAEHQINYASGLPVVLTSVDKLVQWGRSNSLWALSYGLACCAIEMMAAGGSRYDFDRFGTIFRASPRHSEVMIIAGTLCK
KHAEFTRRLYDQMPDPKWVISMGSCANTGGMFNTYSTVQGVDRIIPVDIYVPGCAPRPESFQFALMILQKKIRKEKASRK
IAPKRLV

Sequences:

>Translated_167_residues
MAEHQINYASGLPVVLTSVDKLVQWGRSNSLWALSYGLACCAIEMMAAGGSRYDFDRFGTIFRASPRHSEVMIIAGTLCK
KHAEFTRRLYDQMPDPKWVISMGSCANTGGMFNTYSTVQGVDRIIPVDIYVPGCAPRPESFQFALMILQKKIRKEKASRK
IAPKRLV
>Mature_166_residues
AEHQINYASGLPVVLTSVDKLVQWGRSNSLWALSYGLACCAIEMMAAGGSRYDFDRFGTIFRASPRHSEVMIIAGTLCKK
HAEFTRRLYDQMPDPKWVISMGSCANTGGMFNTYSTVQGVDRIIPVDIYVPGCAPRPESFQFALMILQKKIRKEKASRKI
APKRLV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=143, Percent_Identity=55.9440559440559, Blast_Score=188, Evalue=2e-48,
Organism=Escherichia coli, GI1788624, Length=144, Percent_Identity=52.7777777777778, Blast_Score=177, Evalue=3e-46,
Organism=Escherichia coli, GI1789074, Length=159, Percent_Identity=35.2201257861635, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1788834, Length=121, Percent_Identity=37.1900826446281, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509685, Length=155, Percent_Identity=48.3870967741936, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI18859983, Length=142, Percent_Identity=57.0422535211268, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24642371, Length=142, Percent_Identity=57.0422535211268, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24651058, Length=140, Percent_Identity=56.4285714285714, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18682; Mature: 18551

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHQINYASGLPVVLTSVDKLVQWGRSNSLWALSYGLACCAIEMMAAGGSRYDFDRFGT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IFRASPRHSEVMIIAGTLCKKHAEFTRRLYDQMPDPKWVISMGSCANTGGMFNTYSTVQG
EEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHH
VDRIIPVDIYVPGCAPRPESFQFALMILQKKIRKEKASRKIAPKRLV
HHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AEHQINYASGLPVVLTSVDKLVQWGRSNSLWALSYGLACCAIEMMAAGGSRYDFDRFGT
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IFRASPRHSEVMIIAGTLCKKHAEFTRRLYDQMPDPKWVISMGSCANTGGMFNTYSTVQG
EEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHH
VDRIIPVDIYVPGCAPRPESFQFALMILQKKIRKEKASRKIAPKRLV
HHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA