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The map label for this gene is nuoC [H]

Identifier: 57238590

GI number: 57238590

Start: 1649297

End: 1650088

Strand: Reverse

Name: nuoC [H]

Synonym: CJE1748

Alternate gene names: 57238590

Gene position: 1650088-1649297 (Counterclockwise)

Preceding gene: 57238591

Following gene: 57238589

Centisome position: 92.81

GC content: 30.56

Gene sequence:

>792_bases
ATGAGAAAGTATAGCGATAAAAAAAATGCTCAAACTCAAAATTACTACAAAGATAGATTTTATCACGCGCCACACACTGT
AAAATCTGATGTTAATGAAAGTGTTTTTAAAGAGGATTTTGAAGTTTTAAAAACTCAAGTAGAAATTTTAAATTCCTTTG
TAGAACTTGATTTTTGGGTAATAGAAATTAAAAAAGAAGACAATGTTAAAACTTTGCAAATGCTTAAAACTTTAGGGTAT
TTAAGTTTTACAGAAGCAAGCGCTATTGATTTTATAGCAAGTAAAAATGGTTTTGAAGTGTTTTATCAGCTTTTAAATTT
AGAAAAAAAATTAAGAGTGAGAATAAAAACTTTTGTAGGCGTAAAAGAGCGTTTACAAAGCGTGGCTCATGTTTTTAAAG
GGGCAAATTGGAGTGAGAGAGAAATTTATGATATGTTTGGAATTTTCATCATAAATCATCCCAATTTAAAACGCATTTTA
ATGCCTGATGATTGGTTTGGACATCCGCTTTTGAAAACTTATCCTTTAAAGGGCGATGAGTTTGCAAGATGGTATGAGAT
TGATAAAATTTTTGGCAAAGAATATCGTGAAGTAGTGGGCGAAGAACAAAGAGATTCTGGTTTTGCTGATGATAAAGATA
CGCTAAATTTTGCAAGACTTTATCATGAAGTGCCAAAAGGTGGTCAAAAGAAGGAAATTTCCTTTAAACAAGAATATCAA
GAAGATGAAGGTGTGGCTTTTGTAAAAAAAGTAAAACGTGATGAAGCAAAAATTTTAGAGAAAAGGCGTTAA

Upstream 100 bases:

>100_bases
CTCCACGCCCCGAAAGTTTTCAGTTTGCTTTGATGATTTTGCAAAAAAAGATCCGCAAAGAAAAAGCAAGTCGTAAAATC
GCACCTAAAAGGTTGGTATA

Downstream 100 bases:

>100_bases
AATGCAAATTCCTAGCAAGTTAAAACCTTATTATGAAAATATAGCTTTTGAGCAAGAAGACTCAAAAATGATTATCAACT
TAGGCCCTCAACATCCTTCA

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRKYSDKKNAQTQNYYKDRFYHAPHTVKSDVNESVFKEDFEVLKTQVEILNSFVELDFWVIEIKKEDNVKTLQMLKTLGY
LSFTEASAIDFIASKNGFEVFYQLLNLEKKLRVRIKTFVGVKERLQSVAHVFKGANWSEREIYDMFGIFIINHPNLKRIL
MPDDWFGHPLLKTYPLKGDEFARWYEIDKIFGKEYREVVGEEQRDSGFADDKDTLNFARLYHEVPKGGQKKEISFKQEYQ
EDEGVAFVKKVKRDEAKILEKRR

Sequences:

>Translated_263_residues
MRKYSDKKNAQTQNYYKDRFYHAPHTVKSDVNESVFKEDFEVLKTQVEILNSFVELDFWVIEIKKEDNVKTLQMLKTLGY
LSFTEASAIDFIASKNGFEVFYQLLNLEKKLRVRIKTFVGVKERLQSVAHVFKGANWSEREIYDMFGIFIINHPNLKRIL
MPDDWFGHPLLKTYPLKGDEFARWYEIDKIFGKEYREVVGEEQRDSGFADDKDTLNFARLYHEVPKGGQKKEISFKQEYQ
EDEGVAFVKKVKRDEAKILEKRR
>Mature_263_residues
MRKYSDKKNAQTQNYYKDRFYHAPHTVKSDVNESVFKEDFEVLKTQVEILNSFVELDFWVIEIKKEDNVKTLQMLKTLGY
LSFTEASAIDFIASKNGFEVFYQLLNLEKKLRVRIKTFVGVKERLQSVAHVFKGANWSEREIYDMFGIFIINHPNLKRIL
MPDDWFGHPLLKTYPLKGDEFARWYEIDKIFGKEYREVVGEEQRDSGFADDKDTLNFARLYHEVPKGGQKKEISFKQEYQ
EDEGVAFVKKVKRDEAKILEKRR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=136, Percent_Identity=38.2352941176471, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI145693162, Length=86, Percent_Identity=40.6976744186046, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990788, Length=113, Percent_Identity=39.8230088495575, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656494, Length=121, Percent_Identity=42.1487603305785, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 31254; Mature: 31254

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKYSDKKNAQTQNYYKDRFYHAPHTVKSDVNESVFKEDFEVLKTQVEILNSFVELDFWV
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IEIKKEDNVKTLQMLKTLGYLSFTEASAIDFIASKNGFEVFYQLLNLEKKLRVRIKTFVG
EEEECCCCHHHHHHHHHHCCHHCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHH
VKERLQSVAHVFKGANWSEREIYDMFGIFIINHPNLKRILMPDDWFGHPLLKTYPLKGDE
HHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCCEECCCCCCH
FARWYEIDKIFGKEYREVVGEEQRDSGFADDKDTLNFARLYHEVPKGGQKKEISFKQEYQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHC
EDEGVAFVKKVKRDEAKILEKRR
CCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKYSDKKNAQTQNYYKDRFYHAPHTVKSDVNESVFKEDFEVLKTQVEILNSFVELDFWV
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IEIKKEDNVKTLQMLKTLGYLSFTEASAIDFIASKNGFEVFYQLLNLEKKLRVRIKTFVG
EEEECCCCHHHHHHHHHHCCHHCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHH
VKERLQSVAHVFKGANWSEREIYDMFGIFIINHPNLKRILMPDDWFGHPLLKTYPLKGDE
HHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCCEECCCCCCH
FARWYEIDKIFGKEYREVVGEEQRDSGFADDKDTLNFARLYHEVPKGGQKKEISFKQEYQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHC
EDEGVAFVKKVKRDEAKILEKRR
CCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA