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The map label for this gene is nuoG [H]

Identifier: 57238586

GI number: 57238586

Start: 1644697

End: 1647159

Strand: Reverse

Name: nuoG [H]

Synonym: CJE1744

Alternate gene names: 57238586

Gene position: 1647159-1644697 (Counterclockwise)

Preceding gene: 57238587

Following gene: 57238585

Centisome position: 92.65

GC content: 31.14

Gene sequence:

>2463_bases
ATGACAGTTAAGATTAATGGTATAGATTGCGCCTTTGAAGAAGGCGAATATATCTTAAATATAGCAAGAAGAAATGATAT
TTTTATCCCAGCGATTTGCTATCTTTCGGGCTGTAGTCCTACTTTGGCTTGTCGTATGTGTATGGTTGAAGCTGATGGTA
AAAAGGTATATTCTTGCAATACTAAAGCAAAAGAGGGTATGGTTGTAGAAAGTGATTTACAAAATCTTTGGGATGAAAGA
AATGAGATCATGCAAGCTTATTGTATCAATCATCCTTTAGAATGTGGAGTTTGCGATAAATCAGGCGAGTGTGAATTGCA
AAATTTTACTCATAAAAGTCGTGTAAATGTTCAAAAACATTGGATTAAAGACACGCATAAACCACATAAACATTGGGGAA
TGATTAATTACGATCCCGCACTTTGCATAGTGTGTGAGCGTTGTATTACAGTTTGTAAGGATAAAATCGGAGAAAGTGCT
TTAAAGACTGTTCCTCGTGGCGGAGATAGTGTGGATAATAGCTTTAAAGAGAGCATGGGAAAAGATGCTTATGCGATTTG
GACTAAATTTCAAAAAAGTTTGATAGGCCCTACAAATGGCGACACGCTTGATTGTTCATTTTGTGGAGAATGTACAAGCG
TGTGTCCAACAGGAGCTTTGATAGGTTCGAAATTTCAATACACTTCAAATATTTGGGAACTTAAAAGAATCCCTGCTTCA
AATCCACATTCAAGCGATTGTGAGTTGATGTATTATGATATTAAGCAAAGTGGTATTAGCAATCAAAAAGAAAAAATTTA
TCGTGTGAGTAATGATTTTGCCTTTGCAAGTTTAAATAAGGCTGCAAGATTTGCTTTTGATACGCAAAATGAGGCGGATA
AAGATGAAAAAGCCTTTAAAGAACTTGTGGAGCTTTTTGAGAAAAATGAAATTAAAAACATTAAATTTAATAGTTTTATT
ACCAATGAAGAAGCTTTGATTTTACAAAATTTAAAAAAGAAATTTAATCTTTCTTTAATCAATGAAGAAGCTTTGAAATT
TAAAGAATTTTTACAAGAATTTATCGCTAATTCTGGTGAGTTTTATAGCGCTAATACTCAAGATATAACAAAAAGTGATT
TTTTGGTTGTGGCTGGAATGCTTTTAAGATATGATGCTCCAACGCTTAGTTATAAAATCAATAATGCTTTAGTGATGAAT
AAAGGCTCAGGGCTTTATTTTCATCCTATGGAAGATATGGGTATAGCAAAATATTCTAAAAATTTTATCCCGCACATTCA
TAAAAATGGCGATGAAGAGCAAATTTTATATTTTTTACTTCAAAAATTTAGCCAAGATGAAGGTATCAAAACTCATTTAG
CAGAGTTTTTTGTTAGTGAAAATAAAGAAATAGAAGAAAGTATCAACGAAGAAGTTGTAGAACAAGTCATAGAAAAAGAT
GAAGAAGGCAATGAAATTCAAAAAGAAGTAAAAAAAGTCGTACCTAAAAAAGTAAAAAAAATCATAGAAGTACAACGGTC
TGTTTTTGCTAAAAATTTAGGCATAGATGAAGATAAATTAGAAGATTTATTGCTTAAAAAAGCAAATTTTACTCTTGTTG
TAGGGAGTGATTTTTATTTTCATAAAAATGCGAAAAAACTTGCTAAATTACTTGCTTTGATCCAAAATACTACTCCTTTT
AAAGTCTTTTTAAATCCTACGCATACTAATACCTTAGGTGTGGCTATGATTTGTGATTTGGATAACAATACACAAGAAGG
CAAGACTTTAGGCTACAATGAAAAAGGTGATTTTAGTTTTTCTTATGAAGAGCATGCAAATTTAGCTAGTGCGAGTTTAA
ATCAGCAAGAAGGAACTTTTTTAAATTATGATAAAAGAGTGGTACCAACTAATGCTGCTTTAGAATTTAAGGGATATTTT
TTAAATGATTTGGCTAATGCTTTAGGTTTTGATGAGGAATATACTATAAATTATACTAAGAGACTCCCTATAAATAAAGG
TTTTTCTCCGATTGATTTTGATCATTTAGACAATTTTTATACCAATGCAGGCGATTGTAAAAGGGGATATGAGCTTAATT
TAGAATGTTTCAAACAAGTTGCTAAAAAAGAATTCATCTCTCCAAATTTTGAAAATTTAAGCCTAAAAGAAGATGAAATT
TTGCTTTATAGTGCTAATCCTAGCTATCAATTTGGTAGATTTTCAAATCGTGCTAGTGCGATTAATGAGGTGATTTTTTT
AGGTGTGAGTGAAAATTTAGCTAAAGAGAAAAATTTAAAAGATAAAGATCTTGTAAAACTTAAAATAAAAGATAAAGAAT
TAAGCCTTAGCGTGCGTGTGGATAAGGATATAAAAAATGGAGCTTTCTTGCCGTATTTTGATGAAAAACTTGATACGCTA
AGCTTTTTTGATGAAAGATTTGTTGCGGCAAATTTAGAAAAATTAGGAGCAAGCCATGAGTGA

Upstream 100 bases:

>100_bases
CTAAGCTTTGTTTAGATGAAAATTTACAAGGCACCATAGCTTTTTTAAATTATGAAAATAATGGTTTTGATTTTACTCCA
ATTCGCATAAAGGAAGCAAA

Downstream 100 bases:

>100_bases
TTTTGCTTTTTTTGCTTTAGAGGCTTTAATTAAATGTATTATTATCATTGCAATATTTGCGAGTTTAGCAGGTCTTGCAA
CTTATGCTGAAAGAAAGGTT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MTVKINGIDCAFEEGEYILNIARRNDIFIPAICYLSGCSPTLACRMCMVEADGKKVYSCNTKAKEGMVVESDLQNLWDER
NEIMQAYCINHPLECGVCDKSGECELQNFTHKSRVNVQKHWIKDTHKPHKHWGMINYDPALCIVCERCITVCKDKIGESA
LKTVPRGGDSVDNSFKESMGKDAYAIWTKFQKSLIGPTNGDTLDCSFCGECTSVCPTGALIGSKFQYTSNIWELKRIPAS
NPHSSDCELMYYDIKQSGISNQKEKIYRVSNDFAFASLNKAARFAFDTQNEADKDEKAFKELVELFEKNEIKNIKFNSFI
TNEEALILQNLKKKFNLSLINEEALKFKEFLQEFIANSGEFYSANTQDITKSDFLVVAGMLLRYDAPTLSYKINNALVMN
KGSGLYFHPMEDMGIAKYSKNFIPHIHKNGDEEQILYFLLQKFSQDEGIKTHLAEFFVSENKEIEESINEEVVEQVIEKD
EEGNEIQKEVKKVVPKKVKKIIEVQRSVFAKNLGIDEDKLEDLLLKKANFTLVVGSDFYFHKNAKKLAKLLALIQNTTPF
KVFLNPTHTNTLGVAMICDLDNNTQEGKTLGYNEKGDFSFSYEEHANLASASLNQQEGTFLNYDKRVVPTNAALEFKGYF
LNDLANALGFDEEYTINYTKRLPINKGFSPIDFDHLDNFYTNAGDCKRGYELNLECFKQVAKKEFISPNFENLSLKEDEI
LLYSANPSYQFGRFSNRASAINEVIFLGVSENLAKEKNLKDKDLVKLKIKDKELSLSVRVDKDIKNGAFLPYFDEKLDTL
SFFDERFVAANLEKLGASHE

Sequences:

>Translated_820_residues
MTVKINGIDCAFEEGEYILNIARRNDIFIPAICYLSGCSPTLACRMCMVEADGKKVYSCNTKAKEGMVVESDLQNLWDER
NEIMQAYCINHPLECGVCDKSGECELQNFTHKSRVNVQKHWIKDTHKPHKHWGMINYDPALCIVCERCITVCKDKIGESA
LKTVPRGGDSVDNSFKESMGKDAYAIWTKFQKSLIGPTNGDTLDCSFCGECTSVCPTGALIGSKFQYTSNIWELKRIPAS
NPHSSDCELMYYDIKQSGISNQKEKIYRVSNDFAFASLNKAARFAFDTQNEADKDEKAFKELVELFEKNEIKNIKFNSFI
TNEEALILQNLKKKFNLSLINEEALKFKEFLQEFIANSGEFYSANTQDITKSDFLVVAGMLLRYDAPTLSYKINNALVMN
KGSGLYFHPMEDMGIAKYSKNFIPHIHKNGDEEQILYFLLQKFSQDEGIKTHLAEFFVSENKEIEESINEEVVEQVIEKD
EEGNEIQKEVKKVVPKKVKKIIEVQRSVFAKNLGIDEDKLEDLLLKKANFTLVVGSDFYFHKNAKKLAKLLALIQNTTPF
KVFLNPTHTNTLGVAMICDLDNNTQEGKTLGYNEKGDFSFSYEEHANLASASLNQQEGTFLNYDKRVVPTNAALEFKGYF
LNDLANALGFDEEYTINYTKRLPINKGFSPIDFDHLDNFYTNAGDCKRGYELNLECFKQVAKKEFISPNFENLSLKEDEI
LLYSANPSYQFGRFSNRASAINEVIFLGVSENLAKEKNLKDKDLVKLKIKDKELSLSVRVDKDIKNGAFLPYFDEKLDTL
SFFDERFVAANLEKLGASHE
>Mature_819_residues
TVKINGIDCAFEEGEYILNIARRNDIFIPAICYLSGCSPTLACRMCMVEADGKKVYSCNTKAKEGMVVESDLQNLWDERN
EIMQAYCINHPLECGVCDKSGECELQNFTHKSRVNVQKHWIKDTHKPHKHWGMINYDPALCIVCERCITVCKDKIGESAL
KTVPRGGDSVDNSFKESMGKDAYAIWTKFQKSLIGPTNGDTLDCSFCGECTSVCPTGALIGSKFQYTSNIWELKRIPASN
PHSSDCELMYYDIKQSGISNQKEKIYRVSNDFAFASLNKAARFAFDTQNEADKDEKAFKELVELFEKNEIKNIKFNSFIT
NEEALILQNLKKKFNLSLINEEALKFKEFLQEFIANSGEFYSANTQDITKSDFLVVAGMLLRYDAPTLSYKINNALVMNK
GSGLYFHPMEDMGIAKYSKNFIPHIHKNGDEEQILYFLLQKFSQDEGIKTHLAEFFVSENKEIEESINEEVVEQVIEKDE
EGNEIQKEVKKVVPKKVKKIIEVQRSVFAKNLGIDEDKLEDLLLKKANFTLVVGSDFYFHKNAKKLAKLLALIQNTTPFK
VFLNPTHTNTLGVAMICDLDNNTQEGKTLGYNEKGDFSFSYEEHANLASASLNQQEGTFLNYDKRVVPTNAALEFKGYFL
NDLANALGFDEEYTINYTKRLPINKGFSPIDFDHLDNFYTNAGDCKRGYELNLECFKQVAKKEFISPNFENLSLKEDEIL
LYSANPSYQFGRFSNRASAINEVIFLGVSENLAKEKNLKDKDLVKLKIKDKELSLSVRVDKDIKNGAFLPYFDEKLDTLS
FFDERFVAANLEKLGASHE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=436, Percent_Identity=24.3119266055046, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI145693161, Length=247, Percent_Identity=22.6720647773279, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32566231, Length=421, Percent_Identity=22.8028503562945, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17565758, Length=422, Percent_Identity=22.7488151658768, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193209088, Length=231, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640559, Length=425, Percent_Identity=21.8823529411765, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24640557, Length=425, Percent_Identity=21.8823529411765, Blast_Score=90, Evalue=7e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 93335; Mature: 93204

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKINGIDCAFEEGEYILNIARRNDIFIPAICYLSGCSPTLACRMCMVEADGKKVYSCN
CEEEEECCEEEECCCCEEEEEECCCCEEEEHHHHHCCCCHHHHHHHHEEECCCCEEEECC
TKAKEGMVVESDLQNLWDERNEIMQAYCINHPLECGVCDKSGECELQNFTHKSRVNVQKH
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHCCHHHH
WIKDTHKPHKHWGMINYDPALCIVCERCITVCKDKIGESALKTVPRGGDSVDNSFKESMG
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHC
KDAYAIWTKFQKSLIGPTNGDTLDCSFCGECTSVCPTGALIGSKFQYTSNIWELKRIPAS
CCHHHHHHHHHHHHCCCCCCCEEEEHHCCCHHHHCCCCHHHCCCCHHHHCHHHHHCCCCC
NPHSSDCELMYYDIKQSGISNQKEKIYRVSNDFAFASLNKAARFAFDTQNEADKDEKAFK
CCCCCCCEEEEEECHHCCCCCCHHHHEEECCCEEEHHHHHHHHEEECCCCCCCHHHHHHH
ELVELFEKNEIKNIKFNSFITNEEALILQNLKKKFNLSLINEEALKFKEFLQEFIANSGE
HHHHHHHCCCCCCEEECCEECCCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCCC
FYSANTQDITKSDFLVVAGMLLRYDAPTLSYKINNALVMNKGSGLYFHPMEDMGIAKYSK
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEEECCHHHCCHHHHHC
NFIPHIHKNGDEEQILYFLLQKFSQDEGIKTHLAEFFVSENKEIEESINEEVVEQVIEKD
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EEGNEIQKEVKKVVPKKVKKIIEVQRSVFAKNLGIDEDKLEDLLLKKANFTLVVGSDFYF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCEEE
HKNAKKLAKLLALIQNTTPFKVFLNPTHTNTLGVAMICDLDNNTQEGKTLGYNEKGDFSF
ECCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEE
SYEEHANLASASLNQQEGTFLNYDKRVVPTNAALEFKGYFLNDLANALGFDEEYTINYTK
CHHHHCCHHHHCCCCCCCCEECCCCEEECCCCEEEECCHHHHHHHHHHCCCCCEEEEEEE
RLPINKGFSPIDFDHLDNFYTNAGDCKRGYELNLECFKQVAKKEFISPNFENLSLKEDEI
ECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
LLYSANPSYQFGRFSNRASAINEVIFLGVSENLAKEKNLKDKDLVKLKIKDKELSLSVRV
EEEECCCCCCCCCCCCHHHHHHHEEEEECCHHHHHHCCCCCCCEEEEEEECCEEEEEEEE
DKDIKNGAFLPYFDEKLDTLSFFDERFVAANLEKLGASHE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVKINGIDCAFEEGEYILNIARRNDIFIPAICYLSGCSPTLACRMCMVEADGKKVYSCN
EEEEECCEEEECCCCEEEEEECCCCEEEEHHHHHCCCCHHHHHHHHEEECCCCEEEECC
TKAKEGMVVESDLQNLWDERNEIMQAYCINHPLECGVCDKSGECELQNFTHKSRVNVQKH
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHCCHHHH
WIKDTHKPHKHWGMINYDPALCIVCERCITVCKDKIGESALKTVPRGGDSVDNSFKESMG
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHC
KDAYAIWTKFQKSLIGPTNGDTLDCSFCGECTSVCPTGALIGSKFQYTSNIWELKRIPAS
CCHHHHHHHHHHHHCCCCCCCEEEEHHCCCHHHHCCCCHHHCCCCHHHHCHHHHHCCCCC
NPHSSDCELMYYDIKQSGISNQKEKIYRVSNDFAFASLNKAARFAFDTQNEADKDEKAFK
CCCCCCCEEEEEECHHCCCCCCHHHHEEECCCEEEHHHHHHHHEEECCCCCCCHHHHHHH
ELVELFEKNEIKNIKFNSFITNEEALILQNLKKKFNLSLINEEALKFKEFLQEFIANSGE
HHHHHHHCCCCCCEEECCEECCCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCCC
FYSANTQDITKSDFLVVAGMLLRYDAPTLSYKINNALVMNKGSGLYFHPMEDMGIAKYSK
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEEECCHHHCCHHHHHC
NFIPHIHKNGDEEQILYFLLQKFSQDEGIKTHLAEFFVSENKEIEESINEEVVEQVIEKD
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
EEGNEIQKEVKKVVPKKVKKIIEVQRSVFAKNLGIDEDKLEDLLLKKANFTLVVGSDFYF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCEEE
HKNAKKLAKLLALIQNTTPFKVFLNPTHTNTLGVAMICDLDNNTQEGKTLGYNEKGDFSF
ECCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEE
SYEEHANLASASLNQQEGTFLNYDKRVVPTNAALEFKGYFLNDLANALGFDEEYTINYTK
CHHHHCCHHHHCCCCCCCCEECCCCEEECCCCEEEECCHHHHHHHHHHCCCCCEEEEEEE
RLPINKGFSPIDFDHLDNFYTNAGDCKRGYELNLECFKQVAKKEFISPNFENLSLKEDEI
ECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
LLYSANPSYQFGRFSNRASAINEVIFLGVSENLAKEKNLKDKDLVKLKIKDKELSLSVRV
EEEECCCCCCCCCCCCHHHHHHHEEEEECCHHHHHHCCCCCCCEEEEEEECCEEEEEEEE
DKDIKNGAFLPYFDEKLDTLSFFDERFVAANLEKLGASHE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]