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The map label for this gene is nuoH [H]

Identifier: 57238585

GI number: 57238585

Start: 1643706

End: 1644704

Strand: Reverse

Name: nuoH [H]

Synonym: CJE1743

Alternate gene names: 57238585

Gene position: 1644704-1643706 (Counterclockwise)

Preceding gene: 57238586

Following gene: 57238584

Centisome position: 92.51

GC content: 34.33

Gene sequence:

>999_bases
ATGAGTGATTTTGCTTTTTTTGCTTTAGAGGCTTTAATTAAATGTATTATTATCATTGCAATATTTGCGAGTTTAGCAGG
TCTTGCAACTTATGCTGAAAGAAAGGTTTTAGCTTATTTTCAAAGACGCATAGGGCCTGATATGGTAGGGCCTTTTGGGC
TTATTCAACTTGTAGCTGATATGATAAAACTTTTTACTAAAGAAGATATAATCCCTTCAAATTCGCAAAAATTTATTTTT
GCTATAGCACCTTTGATTTCTGCTATTTGTGCTTTTGTTTCTTTAGCAGCTATTCCTATGCTACCTGAATTTACTTTATT
TGGAAAGGTAATTCAGCCTATAGTGGCAGATATCAATGTAGCTTTGCTTTTTGTCATCGGTACTTCAGGACTTTGCTTTT
ATGCGGTGTTTTTGGGTGGACTTGCAAGTAATAATAAATGGTCGATTTTAGGGGCTGCAAGAGGGCTTGTAGCGATTATT
TCCTATGAAAGCGTAGGAGCTTTAGCTTTGATTGCTATTGTAATGCTTGTAGGTTCTTTTTCTTTGGTGGATATTAACAA
TTATCAAAGCGATGGATTTTTTTCTTGGCTTATTTTTAAACAGCCTTTGGCTTTTGTGCTTTTTATAATTGCTTTATTTA
TAGAGACTAATAGAACTCCGCTTTGTTTGACGGAAAATGATGCTGAAATTGTAGCGGGTTATGGAACGGAGTATTCGGGT
TTAAGATGGGGTATGTTTTTTATAGGTGAATATGCTTCTATGATAGCTGGAGCTATTTTAGTAACTCTTTTGTTTTTAGG
GGGTTTTAATAGCTTTTGGATTATTCCTGGTTGGATTATGATGATAGTAAAATCAAGTTTTATTTTCTTTTGGTATTTTT
GGGCAAGAGCAGCTTTTCCGCAATTGCGTCCAGATCAAGTGATGAAAATGTGCTATTTGATCTTAATCCCTTTAGCGGTT
TTAAACCTTTTAATCACTGCTTTAGCAGTTCTTTTATAG

Upstream 100 bases:

>100_bases
AATGGAGCTTTCTTGCCGTATTTTGATGAAAAACTTGATACGCTAAGCTTTTTTGATGAAAGATTTGTTGCGGCAAATTT
AGAAAAATTAGGAGCAAGCC

Downstream 100 bases:

>100_bases
GAGTTTGATATGAAAAATTATTATTTAGTGGATGAGAAAAGAAAAACTCCTGTTAGCACTTGGGAGAAAATTTCACAAGC
TTTGCGTAGAAGCGTTAAAC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIF
AIAPLISAICAFVSLAAIPMLPEFTLFGKVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAII
SYESVGALALIAIVMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSG
LRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAV
LNLLITALAVLL

Sequences:

>Translated_332_residues
MSDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIF
AIAPLISAICAFVSLAAIPMLPEFTLFGKVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAII
SYESVGALALIAIVMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSG
LRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAV
LNLLITALAVLL
>Mature_331_residues
SDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIFA
IAPLISAICAFVSLAAIPMLPEFTLFGKVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAIIS
YESVGALALIAIVMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSGL
RWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAVL
NLLITALAVLL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=290, Percent_Identity=32.0689655172414, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1788618, Length=323, Percent_Identity=36.8421052631579, Blast_Score=212, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36559; Mature: 36428

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00667 COMPLEX1_ND1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MIKLFTKEDIIPSNSQKFIFAIAPLISAICAFVSLAAIPMLPEFTLFGKVIQPIVADINV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAIISYESVGALALIAIVMLVGSF
HHHEEECCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEEHHHHHHHHHHHHHHHHCCC
SLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCC
LRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QLRPDQVMKMCYLILIPLAVLNLLITALAVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MIKLFTKEDIIPSNSQKFIFAIAPLISAICAFVSLAAIPMLPEFTLFGKVIQPIVADINV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAIISYESVGALALIAIVMLVGSF
HHHEEECCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEEHHHHHHHHHHHHHHHHCCC
SLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCC
LRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QLRPDQVMKMCYLILIPLAVLNLLITALAVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA