Click here to switch to the map view.

The map label for this gene is nuoI [H]

Identifier: 57238584

GI number: 57238584

Start: 1643055

End: 1643696

Strand: Reverse

Name: nuoI [H]

Synonym: CJE1742

Alternate gene names: 57238584

Gene position: 1643696-1643055 (Counterclockwise)

Preceding gene: 57238585

Following gene: 57238583

Centisome position: 92.46

GC content: 34.27

Gene sequence:

>642_bases
ATGAAAAATTATTATTTAGTGGATGAGAAAAGAAAAACTCCTGTTAGCACTTGGGAGAAAATTTCACAAGCTTTGCGTAG
AAGCGTTAAACTAGAGCTTTTTGTAGGGCTTTTTGTGATGATGAGAGAATTACTTAAGAGAAATAATAGCGCTACGATTA
AATATCCTTTTGAAAAGGTAAAACTTGACAATCGTTACCGTGCTGTTCATCGTCTGATGCGTTTTATAGAAAGTGAAAAC
GAAAGATGTATAGGTTGTGGGCTTTGCGAAAAAATTTGCATTAGCAATTGTATTAGAATGGAAACTTCTTTAGATGAAAA
TGGGCGTAAAAAAGTAGGAAATTATAGTATTAATTTAGGGCGTTGTATTTATTGTGGTTTTTGTGCTGAGGTTTGCCCTG
AACTTGCTATAGTGCATGGCACAGAGTATGAAAATGCGGCCGAGCAAAGATCTTATTTTGGTTATAAGCAAGATTTTTTA
ACTCCTATTGATAAGCTTAAAAATCAAGTTGAATTTGAAGGAGCAGGAAGTCTTAGAAAGGATGCAAATTTGTGGGTTAA
AAAAACGCCAAATTATTACGATGCGATGCTTGAAAGTGCCTTAGAAAATCAAAACACACAAGAGCAAGGAGAAAACAAAT
GA

Upstream 100 bases:

>100_bases
TCCAGATCAAGTGATGAAAATGTGCTATTTGATCTTAATCCCTTTAGCGGTTTTAAACCTTTTAATCACTGCTTTAGCAG
TTCTTTTATAGGAGTTTGAT

Downstream 100 bases:

>100_bases
TAGAAAATTTGGCTTTTGTATTTTTTAGTGTAGTGGTTTTAGGTTTTTTTGGCATTGCGGTTTTAAGTAAAAATATGCTT
TATTCTCTTTCGGCTTTAGC

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKNYYLVDEKRKTPVSTWEKISQALRRSVKLELFVGLFVMMRELLKRNNSATIKYPFEKVKLDNRYRAVHRLMRFIESEN
ERCIGCGLCEKICISNCIRMETSLDENGRKKVGNYSINLGRCIYCGFCAEVCPELAIVHGTEYENAAEQRSYFGYKQDFL
TPIDKLKNQVEFEGAGSLRKDANLWVKKTPNYYDAMLESALENQNTQEQGENK

Sequences:

>Translated_213_residues
MKNYYLVDEKRKTPVSTWEKISQALRRSVKLELFVGLFVMMRELLKRNNSATIKYPFEKVKLDNRYRAVHRLMRFIESEN
ERCIGCGLCEKICISNCIRMETSLDENGRKKVGNYSINLGRCIYCGFCAEVCPELAIVHGTEYENAAEQRSYFGYKQDFL
TPIDKLKNQVEFEGAGSLRKDANLWVKKTPNYYDAMLESALENQNTQEQGENK
>Mature_213_residues
MKNYYLVDEKRKTPVSTWEKISQALRRSVKLELFVGLFVMMRELLKRNNSATIKYPFEKVKLDNRYRAVHRLMRFIESEN
ERCIGCGLCEKICISNCIRMETSLDENGRKKVGNYSINLGRCIYCGFCAEVCPELAIVHGTEYENAAEQRSYFGYKQDFL
TPIDKLKNQVEFEGAGSLRKDANLWVKKTPNYYDAMLESALENQNTQEQGENK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=149, Percent_Identity=39.5973154362416, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1788617, Length=135, Percent_Identity=35.5555555555556, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789075, Length=123, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555194, Length=159, Percent_Identity=36.4779874213836, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17864306, Length=151, Percent_Identity=39.0728476821192, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 24803; Mature: 24803

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYYLVDEKRKTPVSTWEKISQALRRSVKLELFVGLFVMMRELLKRNNSATIKYPFEKV
CCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHH
KLDNRYRAVHRLMRFIESENERCIGCGLCEKICISNCIRMETSLDENGRKKVGNYSINLG
HHCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEECCC
RCIYCGFCAEVCPELAIVHGTEYENAAEQRSYFGYKQDFLTPIDKLKNQVEFEGAGSLRK
HHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DANLWVKKTPNYYDAMLESALENQNTQEQGENK
CCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNYYLVDEKRKTPVSTWEKISQALRRSVKLELFVGLFVMMRELLKRNNSATIKYPFEKV
CCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHH
KLDNRYRAVHRLMRFIESENERCIGCGLCEKICISNCIRMETSLDENGRKKVGNYSINLG
HHCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEECCC
RCIYCGFCAEVCPELAIVHGTEYENAAEQRSYFGYKQDFLTPIDKLKNQVEFEGAGSLRK
HHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DANLWVKKTPNYYDAMLESALENQNTQEQGENK
CCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA