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The map label for this gene is nuoN

Identifier: 57238579

GI number: 57238579

Start: 1637588

End: 1638976

Strand: Reverse

Name: nuoN

Synonym: CJE1737

Alternate gene names: 57238579

Gene position: 1638976-1637588 (Counterclockwise)

Preceding gene: 57238580

Following gene: 57238578

Centisome position: 92.19

GC content: 27.57

Gene sequence:

>1389_bases
ATGTTAAATAATTTTTTAAATTTAGAACTTTTAAATATAAGCTTATCTTATCCATTTTTATTTTTAATTACAACTGCAAT
AGTTCTTTTGCTTTGCTCTGGTTTTTGGAAATTTCATCGATCGTTTTATATCGGCATAAGTTCTTTGTCTTTGATTGTAA
GTGCTTTTTTGATTTTAAATAATGCAAATGCTCAAGGTTTAGAAGCAAAAGCTTTTTTGGCTACTTTAAATAATGATATT
GTTTCATTTTATGCTTCTTTGGTGATTTTGTGTTTTTCATTTTTATATCTTTTAATGCAAAAAGAAGAAAATCAAGGTGA
ATTTTATGCTTTATTTTTATTTATGATTGCATCTTTGCTTTTGATGGTTTCAAGCTCAAATTTAGTACTTATTTTTATAG
GACTTGAAAGTTCTTCTTTAGCGCTTTATACTTTAATAGCAATGCGTGGAAGTGATAATGCTATTTCAAGTGCGATAAAA
TACTTTAGTATAGCGGCTGTAGGAGCTGGATTTTTTGTTATGGCTGTAGCTTTTATTTATTTAAAAACAGGAACTTTAGA
TTTATCTGCTAATTTAGCGTTAAAAAATGAGTTTCAAAAAGATCCCATGCTTTTGGGTGCTGGAGTGATGATTTTTGTTC
TTTGTGCAATCAAGCTTTCTTTGGCACCTTTTCATTTTTGGCTTAAAGATGTGTATTATGCAGCACATACAAATTTGGTT
GCTTTTATTTCAGTTGTGCCAAAAGTTGCCATGTTGGTTGTGGTTATTCGTTTGTTTGATTTTTTAAATAATACAGGTTT
TGAATATATCATAATAGTTCTAGCGATTTTTTCTATGCTTATAGGCGCTTTTGCGGCTTTAAGTCAAAACAATATCAAAA
AAATGTTTGCTTATAGTTCTGTAGTGCATTCTTCTTTGGTTTTGATAGCTTGCATTCCTTTATTAAAAGAACAAAATTTT
GATGGAATTTTGCTTGCTATTTTTGGATATTGGACTTTATTTGCTTTTGCAAATTATGCTGTATTTATGATTTTAAGTAA
TTATGAGAATAATTCTTATGAGAGTTTAAATGGGCTTTTGGTTAAAAAACCTTTAATTGCTTTTTGTTTAAGCATTAGTG
TGCTTTCTTTAGCAGGTATTCCGCCTTTTGGAGTATTTTGGGGTAAATTTATGATTTTAAATACAGTAATTTTAAATGGA
TATTGGTATTTGGCGCTTTTTGTGGCTTTATCTTCTGTTATTATGCTTTATGCGTATTTAAAGATTTTAATTCATGTTTT
ATTTATGAAAAATGATAGGGTTTATAATATTAAGTTTAGTTTTATACAAAATTTTATTTTAGCTTTTTGTGTTTGTGTAA
GCATTTTTGCTATATTGTTAATGTTATAA

Upstream 100 bases:

>100_bases
AAGCCGATACAAAAAGATGTGGATAATCTTATAAAAACAATGAATATTAGAGCTGTTGAGCAAAATACTTTAGATTTTTT
ATCTAAAATAGGAGAGGCAA

Downstream 100 bases:

>100_bases
GAGTTTTGCTATAATTATTTTATGAGAATATTATTTTTAATTTTATTAAGTTTTTTAAATGCTTTTGCTTTTGAGCTTGT
TTTAAACACGGGTCGCGAAA

Product: NADH-quinone oxidoreductase, N subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILNNANAQGLEAKAFLATLNNDI
VSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLLLMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIK
YFSIAAVGAGFFVMAVAFIYLKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLV
AFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSSVVHSSLVLIACIPLLKEQNF
DGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLLVKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNG
YWYLALFVALSSVIMLYAYLKILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML

Sequences:

>Translated_462_residues
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILNNANAQGLEAKAFLATLNNDI
VSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLLLMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIK
YFSIAAVGAGFFVMAVAFIYLKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLV
AFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSSVVHSSLVLIACIPLLKEQNF
DGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLLVKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNG
YWYLALFVALSSVIMLYAYLKILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML
>Mature_462_residues
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILNNANAQGLEAKAFLATLNNDI
VSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLLLMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIK
YFSIAAVGAGFFVMAVAFIYLKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLV
AFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSSVVHSSLVLIACIPLLKEQNF
DGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLLVKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNG
YWYLALFVALSSVIMLYAYLKILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831117, Length=356, Percent_Identity=25.561797752809, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI145693160, Length=362, Percent_Identity=33.4254143646409, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788831, Length=374, Percent_Identity=25.9358288770053, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788827, Length=310, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788614, Length=346, Percent_Identity=26.0115606936416, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788829, Length=329, Percent_Identity=25.531914893617, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_CAMJR (Q5HSM5)

Other databases:

- EMBL:   CP000025
- RefSeq:   YP_179710.1
- STRING:   Q5HSM5
- GeneID:   3232364
- GenomeReviews:   CP000025_GR
- KEGG:   cjr:CJE1737
- NMPDR:   fig|195099.3.peg.1762
- TIGR:   CJE1737
- HOGENOM:   HBG747830
- OMA:   AVITHVA
- ProtClustDB:   CLSK879317
- BioCyc:   CJEJ195099:CJE_1737-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 51588; Mature: 51588

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdff6c10)-; HASH(0xeaa6ecc)-; HASH(0xe98afd0)-; HASH(0xf273990)-; HASH(0xef9b83c)-; HASH(0xf395774)-; HASH(0xf3d630c)-; HASH(0xd3f982c)-; HASH(0xea1235c)-; HASH(0xf3d8a58)-; HASH(0xef961b0)-; HASH(0xea0c320)-; HASH(0xf3d6120)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILN
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NANAQGLEAKAFLATLNNDIVSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIKYFSIAAVGAGFFVMAVAFIY
HHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLV
HHCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
VVHSSLVLIACIPLLKEQNFDGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHCCHH
VKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNGYWYLALFVALSSVIMLYAYL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILN
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NANAQGLEAKAFLATLNNDIVSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIKYFSIAAVGAGFFVMAVAFIY
HHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLV
HHCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
VVHSSLVLIACIPLLKEQNFDGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHCCHH
VKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTVILNGYWYLALFVALSSVIMLYAYL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILIHVLFMKNDRVYNIKFSFIQNFILAFCVCVSIFAILLML
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA