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The map label for this gene is lolC [H]

Identifier: 57237769

GI number: 57237769

Start: 957823

End: 959028

Strand: Reverse

Name: lolC [H]

Synonym: CJE1019

Alternate gene names: 57237769

Gene position: 959028-957823 (Counterclockwise)

Preceding gene: 57237770

Following gene: 57237768

Centisome position: 53.94

GC content: 29.6

Gene sequence:

>1206_bases
TTGAATAAAAGCGTTTTAAAATATTTACTTTTTAAATATTTAAGATTTGATAAAGAACAACCCTTTATCAATCTTTCTAT
GCTTTTGGCCTTTTTAGGAGTTTGTGTAGGACTTTGCGTTTTGCTTGTAGCTATGGCAATTATGAATGGTTTTGATAAAG
AATTTGAAAAACGCTTTTTTGTGATGAATTATCCTATTACTATTTTGCCTAAATTTTACGCTCCTGTAAATGATGAATTT
ATAGATGAGTTAAGAAAAACATTTCCAAATTTGTTATTTAGCCCTTATATAAGCACTCAAGTTGTTGTAAAGGGAGATAA
TCGTTTTGAAGGTGGTGTGCTTTTTGGCGTTAATTTTAATGATGAAAAAAAAATAAACGAAGTGGTTGCTAAAGCTTTAA
AGGATGAGAATTTAAGTGGTTTTGATATACTTGTAGGATCAGCACTTACCGATGAATTTGGTTTGCATAAAAATGACAAA
CTTTCACTTATTTTTTCAAATCTTAATCCTAGTGGATTTTCTTTAATACCGCAAACTAAACGTTTTGATGTTAAAGCGCG
TTTTACTTCAGGGCTTGCATTTTATGATAAAGCTTATATGTATACAGATGTTGATGCATTGAAAAAAGTACTTGGAATGC
CTAAAAATCCAAATTATGATGGAATTCATGTATATAGTGATAATGCTTTTAAAGATGTTGAAAAAATTAAATCTTATTTA
AAAGATGATTATGCTGTGGTAGGTTGGTGGGAACAAAATAAAAATTTCTTTTCAGCCTTAGAACTTGAAAAAAGAGCGCT
TTTTATAGTGTTGATGCTTATTATTTTGGTTGCAAGTTTAAATATAGTAAGTTCTTTATTGATGATAGTAATGAATCGTC
GCAGTGAAATAGCACTTTTACTTGCTCTAGGTGCAAGCAAAAATGAGGTAAAAAAGAGTTTTTTTGCCTTAGGTATGCTT
ATTGGTGGTGGTGGTATGATAGTGGGTGTGGTGCTTGCATTTTTTGCTTTATGGCTTTTAGGAAATTTTGATATTGTAAC
TTTACCTGCTGATGTTTATGGAACTAGTAAATTACCACTTGATTTGTCTTTAATGGATTTTTCTTTAACCATTGTGGGTG
CTTTAATAATCATAGCTTTATCATCTTTTTATCCTGCAAAAAAAGCAACTCAAATTAATATTTTAGATACTTTAAGAAAT
GAATAA

Upstream 100 bases:

>100_bases
AGTTTAAAAAAGTTCCACGCAATGCTCCTTGTCCTTGCGGAAGTGGAAAAAAATTTAAAGAATGCCATGGAAAAAGTGGT
CCTAAGCAAGGAATTTTAGC

Downstream 100 bases:

>100_bases
ATTGTAATTTTGGAGATTTTTATTGTCTTTGTTTATTCAAAAAAATAAAAATTTTAAACCTTTAAAACCTCTATCAAAGT
CAAAAATAATCACCAATTTA

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNKSVLKYLLFKYLRFDKEQPFINLSMLLAFLGVCVGLCVLLVAMAIMNGFDKEFEKRFFVMNYPITILPKFYAPVNDEF
IDELRKTFPNLLFSPYISTQVVVKGDNRFEGGVLFGVNFNDEKKINEVVAKALKDENLSGFDILVGSALTDEFGLHKNDK
LSLIFSNLNPSGFSLIPQTKRFDVKARFTSGLAFYDKAYMYTDVDALKKVLGMPKNPNYDGIHVYSDNAFKDVEKIKSYL
KDDYAVVGWWEQNKNFFSALELEKRALFIVLMLIILVASLNIVSSLLMIVMNRRSEIALLLALGASKNEVKKSFFALGML
IGGGGMIVGVVLAFFALWLLGNFDIVTLPADVYGTSKLPLDLSLMDFSLTIVGALIIIALSSFYPAKKATQINILDTLRN
E

Sequences:

>Translated_401_residues
MNKSVLKYLLFKYLRFDKEQPFINLSMLLAFLGVCVGLCVLLVAMAIMNGFDKEFEKRFFVMNYPITILPKFYAPVNDEF
IDELRKTFPNLLFSPYISTQVVVKGDNRFEGGVLFGVNFNDEKKINEVVAKALKDENLSGFDILVGSALTDEFGLHKNDK
LSLIFSNLNPSGFSLIPQTKRFDVKARFTSGLAFYDKAYMYTDVDALKKVLGMPKNPNYDGIHVYSDNAFKDVEKIKSYL
KDDYAVVGWWEQNKNFFSALELEKRALFIVLMLIILVASLNIVSSLLMIVMNRRSEIALLLALGASKNEVKKSFFALGML
IGGGGMIVGVVLAFFALWLLGNFDIVTLPADVYGTSKLPLDLSLMDFSLTIVGALIIIALSSFYPAKKATQINILDTLRN
E
>Mature_401_residues
MNKSVLKYLLFKYLRFDKEQPFINLSMLLAFLGVCVGLCVLLVAMAIMNGFDKEFEKRFFVMNYPITILPKFYAPVNDEF
IDELRKTFPNLLFSPYISTQVVVKGDNRFEGGVLFGVNFNDEKKINEVVAKALKDENLSGFDILVGSALTDEFGLHKNDK
LSLIFSNLNPSGFSLIPQTKRFDVKARFTSGLAFYDKAYMYTDVDALKKVLGMPKNPNYDGIHVYSDNAFKDVEKIKSYL
KDDYAVVGWWEQNKNFFSALELEKRALFIVLMLIILVASLNIVSSLLMIVMNRRSEIALLLALGASKNEVKKSFFALGML
IGGGGMIVGVVLAFFALWLLGNFDIVTLPADVYGTSKLPLDLSLMDFSLTIVGALIIIALSSFYPAKKATQINILDTLRN
E

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=407, Percent_Identity=21.8673218673219, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787362, Length=398, Percent_Identity=23.6180904522613, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45035; Mature: 45035

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSVLKYLLFKYLRFDKEQPFINLSMLLAFLGVCVGLCVLLVAMAIMNGFDKEFEKRFF
CCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEE
VMNYPITILPKFYAPVNDEFIDELRKTFPNLLFSPYISTQVVVKGDNRFEGGVLFGVNFN
EEECCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCC
DEKKINEVVAKALKDENLSGFDILVGSALTDEFGLHKNDKLSLIFSNLNPSGFSLIPQTK
CHHHHHHHHHHHHHCCCCCCHHEEECCHHHHHHCCCCCCCEEEEEECCCCCCCEECCCCC
RFDVKARFTSGLAFYDKAYMYTDVDALKKVLGMPKNPNYDGIHVYSDNAFKDVEKIKSYL
CEEEEEHHHCCCHHHHHHHEEECHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
KDDYAVVGWWEQNKNFFSALELEKRALFIVLMLIILVASLNIVSSLLMIVMNRRSEIALL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LALGASKNEVKKSFFALGMLIGGGGMIVGVVLAFFALWLLGNFDIVTLPADVYGTSKLPL
EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCCE
DLSLMDFSLTIVGALIIIALSSFYPAKKATQINILDTLRNE
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCC
>Mature Secondary Structure
MNKSVLKYLLFKYLRFDKEQPFINLSMLLAFLGVCVGLCVLLVAMAIMNGFDKEFEKRFF
CCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEE
VMNYPITILPKFYAPVNDEFIDELRKTFPNLLFSPYISTQVVVKGDNRFEGGVLFGVNFN
EEECCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCC
DEKKINEVVAKALKDENLSGFDILVGSALTDEFGLHKNDKLSLIFSNLNPSGFSLIPQTK
CHHHHHHHHHHHHHCCCCCCHHEEECCHHHHHHCCCCCCCEEEEEECCCCCCCEECCCCC
RFDVKARFTSGLAFYDKAYMYTDVDALKKVLGMPKNPNYDGIHVYSDNAFKDVEKIKSYL
CEEEEEHHHCCCHHHHHHHEEECHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
KDDYAVVGWWEQNKNFFSALELEKRALFIVLMLIILVASLNIVSSLLMIVMNRRSEIALL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LALGASKNEVKKSFFALGMLIGGGGMIVGVVLAFFALWLLGNFDIVTLPADVYGTSKLPL
EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCCE
DLSLMDFSLTIVGALIIIALSSFYPAKKATQINILDTLRNE
EEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]