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The map label for this gene is yhdH [H]

Identifier: 57237763

GI number: 57237763

Start: 949135

End: 950469

Strand: Reverse

Name: yhdH [H]

Synonym: CJE1013

Alternate gene names: 57237763

Gene position: 950469-949135 (Counterclockwise)

Preceding gene: 57237766

Following gene: 57237762

Centisome position: 53.46

GC content: 30.49

Gene sequence:

>1335_bases
TTGAGTTCTAAATTTTCAAAAATAGGTTTCATTTTAGCGGTAGCAGGTTCAGCGGTGGGCTTGGGTAATGCTTGGAAATT
TCCAACACTAGTAGGTCAAAGTGGTGGATCTGCTTTTATCTTGCTTTATATAATTCTTACTTTAGGTGTAGGTTTTGTGA
TATTTTTAGCTGAGCTTAGCATAGGAAAAATTAGTGAAAAAGATCCGGTTAATGCCTATGAAAAGTTAGCACCTTCAAAT
AAAAAAGCTTGGTCTTATGTTGGTTTTACTATGGTGGGGGCGATTTTAATAGTTTCTTTTTATACCTTGGTGATTGGCTG
GATAGTTAAATATGTGTTTTTAAGTATCACTGGAAATTTGCCTATGGATCTAGAAGTAAGTAAAGCACAGTTTGGATTTT
TTATAAGTGAGGATTTTTTAAGTCAGTTTATTTGTTTTACTTTGGTTTTTTTATGTGTTTTTTATATTGTTTCTAAAGGT
GTTAAGAATGGGATTGAAAAGTTAAATGTTTGGATGATGCCTTCATTGTTTATTTTACTTATTTTGATGCTTGTTTATGC
TATTAGCAAAGATGGTTTTATAATGGCGGTTAAATTTCTTTTTGTACCTGATTTTTCCAAAATCAACACTTCAAACGTTC
TTGAAGCCTTAGGACTTGCTTTTTTTAGTCTTTCTTTGGGCGTTGGAACGATTATTACTTATTCTGCTAGTCTGCCTGAT
AAAACTAATTTTATTACCAGTACTTTAAATATTATTTTTATCAATCTTTTAGTTGGTTTATTAATGGGTTTGGTTGTTTT
TACTTTTATCTTTGAATTTGGTTACAATCCTAATCAGCAAGGACCAGGACTTGTTTTTATTTCCTTAGCTACTTTATTTG
AAAAAATTGGAGTGATTGGTTGTATTTTTGGAGCAGCGTTTTTTATTTCTTTAATCTTTGCTGGTATTACTTCAGCTGTT
TCAATGATAGAGCCTTTCACTTTTTACCTTATTAATACTTTTGGTATGAGCCGTAAAAAAGCTTTGATTTTAATAGGAAT
TGTTGTTTATATTTTAGGAATGTTGTGTATTTTATCTTCTTTAAAAAGTACTCAGTTTGGATTTTTTGGAATGAGTTTTT
TTGATTTGCTTGATAGTGTTTCAAGCAAGGTTATTATGCCTTTAGGTGGAATTTTGGCAGCTATTTTTGTGGGATTTGTG
ATGAAAAAAGAAGCTTTAAAAATTTTATTTAAACCTTATATGAGGGGTATATTTTTTGAACTTTGGTATGTGTTTTTGAG
ATTTATTTCCCCTTTGGCTGTTGTTATAGTTATGATAGCCGCTTTTTTAAAGTGA

Upstream 100 bases:

>100_bases
ATTCACATTTTTGATTTAAATTTGATTGTTTTCAATAAAGCTTAAAAGTTTTTTTGCTTTAATAATATTTTAAAATAATT
TTTAAGTTAAGGTTGCAACA

Downstream 100 bases:

>100_bases
GTTTGAAAAATAATGAGAACATATTTTTCAAAAATCGGTTTTGTATTGGCTGTTGCTGGTGGAGCCGTTGGTTTAGGTAA
TGCTTGGAAATTTCCAACTT

Product: sodium transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSSKFSKIGFILAVAGSAVGLGNAWKFPTLVGQSGGSAFILLYIILTLGVGFVIFLAELSIGKISEKDPVNAYEKLAPSN
KKAWSYVGFTMVGAILIVSFYTLVIGWIVKYVFLSITGNLPMDLEVSKAQFGFFISEDFLSQFICFTLVFLCVFYIVSKG
VKNGIEKLNVWMMPSLFILLILMLVYAISKDGFIMAVKFLFVPDFSKINTSNVLEALGLAFFSLSLGVGTIITYSASLPD
KTNFITSTLNIIFINLLVGLLMGLVVFTFIFEFGYNPNQQGPGLVFISLATLFEKIGVIGCIFGAAFFISLIFAGITSAV
SMIEPFTFYLINTFGMSRKKALILIGIVVYILGMLCILSSLKSTQFGFFGMSFFDLLDSVSSKVIMPLGGILAAIFVGFV
MKKEALKILFKPYMRGIFFELWYVFLRFISPLAVVIVMIAAFLK

Sequences:

>Translated_444_residues
MSSKFSKIGFILAVAGSAVGLGNAWKFPTLVGQSGGSAFILLYIILTLGVGFVIFLAELSIGKISEKDPVNAYEKLAPSN
KKAWSYVGFTMVGAILIVSFYTLVIGWIVKYVFLSITGNLPMDLEVSKAQFGFFISEDFLSQFICFTLVFLCVFYIVSKG
VKNGIEKLNVWMMPSLFILLILMLVYAISKDGFIMAVKFLFVPDFSKINTSNVLEALGLAFFSLSLGVGTIITYSASLPD
KTNFITSTLNIIFINLLVGLLMGLVVFTFIFEFGYNPNQQGPGLVFISLATLFEKIGVIGCIFGAAFFISLIFAGITSAV
SMIEPFTFYLINTFGMSRKKALILIGIVVYILGMLCILSSLKSTQFGFFGMSFFDLLDSVSSKVIMPLGGILAAIFVGFV
MKKEALKILFKPYMRGIFFELWYVFLRFISPLAVVIVMIAAFLK
>Mature_443_residues
SSKFSKIGFILAVAGSAVGLGNAWKFPTLVGQSGGSAFILLYIILTLGVGFVIFLAELSIGKISEKDPVNAYEKLAPSNK
KAWSYVGFTMVGAILIVSFYTLVIGWIVKYVFLSITGNLPMDLEVSKAQFGFFISEDFLSQFICFTLVFLCVFYIVSKGV
KNGIEKLNVWMMPSLFILLILMLVYAISKDGFIMAVKFLFVPDFSKINTSNVLEALGLAFFSLSLGVGTIITYSASLPDK
TNFITSTLNIIFINLLVGLLMGLVVFTFIFEFGYNPNQQGPGLVFISLATLFEKIGVIGCIFGAAFFISLIFAGITSAVS
MIEPFTFYLINTFGMSRKKALILIGIVVYILGMLCILSSLKSTQFGFFGMSFFDLLDSVSSKVIMPLGGILAAIFVGFVM
KKEALKILFKPYMRGIFFELWYVFLRFISPLAVVIVMIAAFLK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507041, Length=456, Percent_Identity=25.8771929824561, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507043, Length=412, Percent_Identity=23.5436893203883, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI134304856, Length=332, Percent_Identity=26.2048192771084, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21361581, Length=430, Percent_Identity=21.6279069767442, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI188528618, Length=417, Percent_Identity=23.2613908872902, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI289191351, Length=506, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4557046, Length=506, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI289191377, Length=507, Percent_Identity=24.2603550295858, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI171184408, Length=442, Percent_Identity=23.7556561085973, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI171184406, Length=442, Percent_Identity=23.7556561085973, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI171184404, Length=442, Percent_Identity=23.7556561085973, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI58219014, Length=292, Percent_Identity=29.1095890410959, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7657587, Length=455, Percent_Identity=21.0989010989011, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI33354281, Length=292, Percent_Identity=28.0821917808219, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI197276623, Length=339, Percent_Identity=25.3687315634218, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI54607094, Length=339, Percent_Identity=25.3687315634218, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI51468073, Length=304, Percent_Identity=23.6842105263158, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI194018524, Length=297, Percent_Identity=25.2525252525253, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI197276625, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361693, Length=119, Percent_Identity=34.453781512605, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI92859670, Length=117, Percent_Identity=35.8974358974359, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=477, Percent_Identity=25.9958071278826, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17555248, Length=137, Percent_Identity=31.3868613138686, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133952791, Length=246, Percent_Identity=26.4227642276423, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136952, Length=425, Percent_Identity=23.7647058823529, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281364394, Length=432, Percent_Identity=24.0740740740741, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574704, Length=432, Percent_Identity=24.0740740740741, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136950, Length=432, Percent_Identity=24.0740740740741, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574702, Length=432, Percent_Identity=24.0740740740741, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24762620, Length=405, Percent_Identity=27.4074074074074, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45551183, Length=448, Percent_Identity=24.3303571428571, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281365034, Length=431, Percent_Identity=23.6658932714617, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639516, Length=306, Percent_Identity=27.1241830065359, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24639514, Length=306, Percent_Identity=27.1241830065359, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221329674, Length=306, Percent_Identity=27.1241830065359, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24652942, Length=437, Percent_Identity=21.7391304347826, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921936, Length=404, Percent_Identity=23.7623762376238, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45551088, Length=405, Percent_Identity=21.7283950617284, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582567, Length=473, Percent_Identity=23.4672304439746, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364136, Length=509, Percent_Identity=22.0039292730845, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24661428, Length=428, Percent_Identity=22.8971962616822, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363702, Length=466, Percent_Identity=22.9613733905579, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24655079, Length=292, Percent_Identity=25.3424657534247, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550877, Length=248, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654186, Length=116, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48809; Mature: 48677

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKFSKIGFILAVAGSAVGLGNAWKFPTLVGQSGGSAFILLYIILTLGVGFVIFLAELS
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGKISEKDPVNAYEKLAPSNKKAWSYVGFTMVGAILIVSFYTLVIGWIVKYVFLSITGNL
HCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMDLEVSKAQFGFFISEDFLSQFICFTLVFLCVFYIVSKGVKNGIEKLNVWMMPSLFILL
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILMLVYAISKDGFIMAVKFLFVPDFSKINTSNVLEALGLAFFSLSLGVGTIITYSASLPD
HHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHEEECCCCC
KTNFITSTLNIIFINLLVGLLMGLVVFTFIFEFGYNPNQQGPGLVFISLATLFEKIGVIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHH
CIFGAAFFISLIFAGITSAVSMIEPFTFYLINTFGMSRKKALILIGIVVYILGMLCILSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKSTQFGFFGMSFFDLLDSVSSKVIMPLGGILAAIFVGFVMKKEALKILFKPYMRGIFFE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWYVFLRFISPLAVVIVMIAAFLK
HHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SSKFSKIGFILAVAGSAVGLGNAWKFPTLVGQSGGSAFILLYIILTLGVGFVIFLAELS
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGKISEKDPVNAYEKLAPSNKKAWSYVGFTMVGAILIVSFYTLVIGWIVKYVFLSITGNL
HCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMDLEVSKAQFGFFISEDFLSQFICFTLVFLCVFYIVSKGVKNGIEKLNVWMMPSLFILL
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILMLVYAISKDGFIMAVKFLFVPDFSKINTSNVLEALGLAFFSLSLGVGTIITYSASLPD
HHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHEEECCCCC
KTNFITSTLNIIFINLLVGLLMGLVVFTFIFEFGYNPNQQGPGLVFISLATLFEKIGVIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHH
CIFGAAFFISLIFAGITSAVSMIEPFTFYLINTFGMSRKKALILIGIVVYILGMLCILSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKSTQFGFFGMSFFDLLDSVSSKVIMPLGGILAAIFVGFVMKKEALKILFKPYMRGIFFE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWYVFLRFISPLAVVIVMIAAFLK
HHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]