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The map label for this gene is yhdH [H]

Identifier: 57237762

GI number: 57237762

Start: 947782

End: 949122

Strand: Reverse

Name: yhdH [H]

Synonym: CJE1012

Alternate gene names: 57237762

Gene position: 949122-947782 (Counterclockwise)

Preceding gene: 57237763

Following gene: 57237761

Centisome position: 53.39

GC content: 27.44

Gene sequence:

>1341_bases
ATGAGAACATATTTTTCAAAAATCGGTTTTGTATTGGCTGTTGCTGGTGGAGCCGTTGGTTTAGGTAATGCTTGGAAATT
TCCAACTTTAAGCGCAGAAAATGGTGGTTTTGTTTTTGTGCTTTTATATTTGTTTTTTACTTTAACTATAGGATTTAGTA
TTTTTTTGGCTGAAGTGGCTATGGGACGTTTAAGTAAAAGTGATCTTGCAAATGCTTATTCAAATCTTGCCATAAAATAT
GGCAATAGATGGCGATATGGCGGCGTTTTTATGTTAGGTGGTATTTTTATCCTCTCTTTTTATCTAGTTATCATGGGATG
GGTTTTAAAATATACTGTAGTGAGTCTTTATTATCTTCCTAAAACTTTAGATGAAGCAGCAAGTAATTTTCAGAATGTAA
TTACTACAAATTTGACAAGTTCTGTTTTTTTCTTCACTTTATCTTTTTTTCTTACTTTATTGATAGTATCTAAAGGTTTA
ATCAAAGGGATTGAAAAATTAAACGTTGTTATAATGCCTAGCTTATTTTTAATGCTTGTTTTTATGTTGTTTTATTGCAT
GGGATTTAAGCAAGGTTTTGCAAATGCTTTTTCTTATTTATTTTATCCCGATTTTTCACATTTTAAATTCAGCTCTATTG
CCGAAGCTTTAGGGCTTGCATTTTTTACCTTATGCTTGGGAATAGGTTGTATAGTTACATATTCATCGGCCTTGGATAAA
AAAACAAATTTTATAAAAAGTTCAGTGTATATTGTTTTGATTAATTTATTGATTTCTTTTATTATGGGACTTATTGTTTT
TACTTTTATCTTTGAATTTGGAGCCGATCCGCATACTCAAGGAGCAGGAATTGTTTTTGTATCCTTGATGAGTTTGTTTA
ATCAACTTGGAGCTTTAGGCTATATTTTTGCATTTTGTTTTTTCTTAGCACTTTTTTTTGCTGGTATTACTTCAGCTATT
TCAATGATAGAGCCTTTAACTTTTTATATGATTAATAACTATCAAATTTCTCGTGTTAAAGCTCTATTTTTAATAGGTTT
ATTTGTTTTTGTTTTTGGAATTTGTTGTATCTTGTCATTAAATTTAAATTTTTTTTCTATGTTTAGTTTTTTTGGCAAAG
ATTTTTTTACTTTATTAGATAAATTAACTTCAAATTTTTTACTTCCACTTGGTGCTATAGTATGCTCTATATTTGTAGGT
TTTTTTATGAATAAAAAACAAATTTATAAAATTTTTTCTAAATTTATAAGTCGAAAAATTTTCTTAATTTGGTTGTTTTT
TATTCGTTTTATATCGCCTATAGCAATAATTTTGGTAATGTGTTATCAAATTTTTGTATAA

Upstream 100 bases:

>100_bases
TATATTTTTTGAACTTTGGTATGTGTTTTTGAGATTTATTTCCCCTTTGGCTGTTGTTATAGTTATGATAGCCGCTTTTT
TAAAGTGAGTTTGAAAAATA

Downstream 100 bases:

>100_bases
TAATGAAAAAATATTTTTTTAAGGAAAAATAATGGCTAAAAAATTCATCGATGTAATGGATACAAGCTTTAGGGACGGTT
TTCAGTCTGTTTATGGAGCT

Product: sodium transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRTYFSKIGFVLAVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVAMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFILSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNVITTNLTSSVFFFTLSFFLTLLIVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGAGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAI
SMIEPLTFYMINNYQISRVKALFLIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV

Sequences:

>Translated_446_residues
MRTYFSKIGFVLAVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVAMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFILSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNVITTNLTSSVFFFTLSFFLTLLIVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGAGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAI
SMIEPLTFYMINNYQISRVKALFLIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV
>Mature_446_residues
MRTYFSKIGFVLAVAGGAVGLGNAWKFPTLSAENGGFVFVLLYLFFTLTIGFSIFLAEVAMGRLSKSDLANAYSNLAIKY
GNRWRYGGVFMLGGIFILSFYLVIMGWVLKYTVVSLYYLPKTLDEAASNFQNVITTNLTSSVFFFTLSFFLTLLIVSKGL
IKGIEKLNVVIMPSLFLMLVFMLFYCMGFKQGFANAFSYLFYPDFSHFKFSSIAEALGLAFFTLCLGIGCIVTYSSALDK
KTNFIKSSVYIVLINLLISFIMGLIVFTFIFEFGADPHTQGAGIVFVSLMSLFNQLGALGYIFAFCFFLALFFAGITSAI
SMIEPLTFYMINNYQISRVKALFLIGLFVFVFGICCILSLNLNFFSMFSFFGKDFFTLLDKLTSNFLLPLGAIVCSIFVG
FFMNKKQIYKIFSKFISRKIFLIWLFFIRFISPIAIILVMCYQIFV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507041, Length=489, Percent_Identity=24.1308793456033, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI188528618, Length=492, Percent_Identity=22.3577235772358, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361581, Length=430, Percent_Identity=23.2558139534884, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI289191351, Length=498, Percent_Identity=22.6907630522088, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4557046, Length=498, Percent_Identity=22.6907630522088, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI289191377, Length=498, Percent_Identity=22.6907630522088, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=25.2459016393443, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI92859670, Length=523, Percent_Identity=21.414913957935, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184408, Length=436, Percent_Identity=23.6238532110092, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184406, Length=436, Percent_Identity=23.6238532110092, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI171184404, Length=436, Percent_Identity=23.6238532110092, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI58219014, Length=297, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4507043, Length=369, Percent_Identity=23.5772357723577, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI194018524, Length=303, Percent_Identity=26.4026402640264, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=412, Percent_Identity=24.2718446601942, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554804, Length=480, Percent_Identity=21.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639514, Length=508, Percent_Identity=23.0314960629921, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221329674, Length=508, Percent_Identity=23.0314960629921, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24762620, Length=404, Percent_Identity=24.7524752475248, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639516, Length=307, Percent_Identity=26.0586319218241, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45551088, Length=376, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652942, Length=376, Percent_Identity=25, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582567, Length=413, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50312; Mature: 50312

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]