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The map label for this gene is rnpA

Identifier: 159184284

GI number: 159184284

Start: 377862

End: 378245

Strand: Reverse

Name: rnpA

Synonym: Atu0385

Alternate gene names: 159184284

Gene position: 378245-377862 (Counterclockwise)

Preceding gene: 159185415

Following gene: 159184283

Centisome position: 13.31

GC content: 57.03

Gene sequence:

>384_bases
ATGAGCGAGACTAAAAAACAACCCGGCCGGCTTAAAAACCGGTCGGAGTTTCTTGCCGTTCAGGCGGGGGAAAAACGGCG
GGGAAGCACCTTTCTTGTGGAAGTGCTTGACCGGAGAGCCCCGGAAACCGAGCCTCGCGTCGGTTTTACCGTAACAAAAA
GACAAGGCAACGCGGTCGAGCGAAATCGCATGCGCCGCCGTCTCAAGGAAGCCGTCAGGCTTTCTGCCGGGGTCGCAATG
AAGCCCGGTCATGACTATGTGATTGTCGCCCGCAGGGACGTACTCGATACCGCCTTCCCGAAACTTCAGTCTCTCCTTAT
CGAGCGCATTGAAGGAACGGCGAAACCGAAACGGTCCCAGGAGACCCGCTCCAGGAAAGAATGA

Upstream 100 bases:

>100_bases
TGCCGGCGGCCGCAAGGTTCTCGCAGCCCGCCGTGCGCGCGGCCGCGCACGTCTGTCGGCTTAATTGCCGAGCCTGTGGC
CCGATGAAAGTCGCGGGCAC

Downstream 100 bases:

>100_bases
TGGAAAAGAACCGCAATTACTTCATCGCGATAGCCCTTTCGGTTGTCATCGTCCTCGCCTGGCAATTCCTTTACATGAAT
CCGCGCATCGAGCAGCAGCG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MSETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVERNRMRRRLKEAVRLSAGVAM
KPGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQETRSRKE

Sequences:

>Translated_127_residues
MSETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVERNRMRRRLKEAVRLSAGVAM
KPGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQETRSRKE
>Mature_126_residues
SETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVERNRMRRRLKEAVRLSAGVAMK
PGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQETRSRKE

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_AGRT5 (Q8UIB2)

Other databases:

- EMBL:   AE007869
- PIR:   AI2623
- RefSeq:   NP_353416.2
- ProteinModelPortal:   Q8UIB2
- SMR:   Q8UIB2
- STRING:   Q8UIB2
- GeneID:   1132423
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0385
- NMPDR:   fig|176299.3.peg.839
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   HDYVIVA
- ProtClustDB:   PRK01313
- BioCyc:   ATUM176299-1:ATU0385-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14557; Mature: 14426

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHH
RNRMRRRLKEAVRLSAGVAMKPGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQ
HHHHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ETRSRKE
HHHCCCC
>Mature Secondary Structure 
SETKKQPGRLKNRSEFLAVQAGEKRRGSTFLVEVLDRRAPETEPRVGFTVTKRQGNAVE
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHH
RNRMRRRLKEAVRLSAGVAMKPGHDYVIVARRDVLDTAFPKLQSLLIERIEGTAKPKRSQ
HHHHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ETRSRKE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194