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The map label for this gene is mviN [H]

Identifier: 159184270

GI number: 159184270

Start: 342473

End: 344062

Strand: Direct

Name: mviN [H]

Synonym: Atu0347

Alternate gene names: 159184270

Gene position: 342473-344062 (Clockwise)

Preceding gene: 159184269

Following gene: 15887699

Centisome position: 12.05

GC content: 60.06

Gene sequence:

>1590_bases
ATGAGTCTGATCGGCAAGTTCGCCACCGTTGGCACCGCCACGCTCGGCAGCCGCATTTTTGGCTTTCTGCGCGAAACGCT
GATGGCCGCTGCCGTCGGTACTGGTCCGGTGGCTGACGCCTTCAATGCCGCGTTCCGATTTCCCAACACCTTCCGGCGGC
TTTTTGCCGAAGGCGCCTTTAACTCGGCTTTCGTGCCGCTTTTCGCCAAGGAAATCGAGGCGAACGGCATGGAGGGTGCA
AGGCGCTTTTCCGAAGAGGTTTTCGGCGTTCTCTTCACCGTGCTTCTGGCCCTGACAATTTTGATGGAATTGTCGATGCC
GTTCATCGTGCGCACGGTAATCGCGCCGGGCTTTCTGGAAGACCCGGTGAAGTTCGACAACACCGTCCGCCTCGCCACCA
TCATGTTCCCTTATCTCGCCTGCATGTCGCTCGCGGCGATGATGGGCGGCATGCTGAATTCGCTGCACCGTTATTTTGCG
GCGGCAATCGCACCTGTCTTCCTCAATATCATCCTCATCGGCGTGCTCGCCTTGGCATGGTGGAAGAATTACGATCCCCT
GCAGGTGGGTTATGCGCTCTCGTGGGGGGTGATGGCAGCGGGTCTGGTGCAACTCGCCATCGTCTGGATCGCCGTGCGCA
ACGCCGGCATGCGGATCGGTCTCCGTAGGCCGCGGCTAACGAAAAATGTGCAGCGGCTGCTGGTTCTTGCCCTGCCGGCG
GCAATCACCGGCGGCATCACCCAGATCAACCTTCTGATCAACACCAATATTGCGTCAGCCGGCGAGGGCGTGATCTCCTC
GCTTGCTTATGCCGACCGGATTTACCAGCTGCCGCTGGGCGTTGTCGGCATTGCCGTGGCCACCGTGCTTTTGCCGGAAC
TTGCACGCGCTTTGCGCGGCGGGCACATGGTGGAGGCGGGAAGTCTGCAGAACCGCTCGGTCGAATTCGTATTATTCCTG
ACCTTGCCTGCGGCGGCGGCTCTTCTTGTCATGGCCGAGCCCATCGTTCGTTTTCTTTATGAACGCGGCAACTTCTCACC
TTCGGCTACCATCACCGTCGCGCAGATCCTCGGTATCTATGGTCTGGGTTTGCCGGCTTTCGTGCTGATCAAGGCCTTCA
TTCCGGGCTTTTTCGCCCGCGAGGACACGCGCACGCCGATGATCTTCGCGGCGGTTTCCGTGGTTGTGAATGTCTCCCTG
GCACTGACGCTGTTTCCGCGTCTCGGCGGCCCAGGCATTGCGATTGCCGAGATCACTGCCGGCTGGGTCAATGCCGCCTT
GCTGTTCGGCATGCTTTTGTGGCGCGGTCACTGGCATGTGGATATTCCGCTGCTGACCCGCATTCCGCGTCTGCTTCTGG
CCGCGGCTCTGATGGCCGGTTTTGTGCATTATGCGCTGACCTGGCTGAGTTTCGAGCTGTCGTCGGCCTCGTCCATCTTC
GTCCGGGCAGGAACCATCATGGGCCTCGTCTTTACGGCCATGCTGGTCTATTTCGTGCTGGCTTTCGTTTCTGGCGGTGC
CGATATCGGCATGGTCAAGAGAGCCGTGCGCAAGCGCGGTAAAAAGACCGCCGAGACGGAGGTGGGCTGA

Upstream 100 bases:

>100_bases
CAGGAAGACGAATTGCGTGACCGCATGCCGAACGGCATCATCGCCCATCCAGACGTGGCGGCGCTGCCGGCCGCGCGCAC
GGCAAAGGCTTGATATCCCC

Downstream 100 bases:

>100_bases
TGTCCTTTTCTGAAAACCGCCGCATCGCGCTGGTCACGCTTGTCGTGGATAACTATGATCGGGCAAAGGCGTTTTACTGC
GATGTTCTCGGCTTCGAGTG

Product: virulence factor MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSLIGKFATVGTATLGSRIFGFLRETLMAAAVGTGPVADAFNAAFRFPNTFRRLFAEGAFNSAFVPLFAKEIEANGMEGA
RRFSEEVFGVLFTVLLALTILMELSMPFIVRTVIAPGFLEDPVKFDNTVRLATIMFPYLACMSLAAMMGGMLNSLHRYFA
AAIAPVFLNIILIGVLALAWWKNYDPLQVGYALSWGVMAAGLVQLAIVWIAVRNAGMRIGLRRPRLTKNVQRLLVLALPA
AITGGITQINLLINTNIASAGEGVISSLAYADRIYQLPLGVVGIAVATVLLPELARALRGGHMVEAGSLQNRSVEFVLFL
TLPAAAALLVMAEPIVRFLYERGNFSPSATITVAQILGIYGLGLPAFVLIKAFIPGFFAREDTRTPMIFAAVSVVVNVSL
ALTLFPRLGGPGIAIAEITAGWVNAALLFGMLLWRGHWHVDIPLLTRIPRLLLAAALMAGFVHYALTWLSFELSSASSIF
VRAGTIMGLVFTAMLVYFVLAFVSGGADIGMVKRAVRKRGKKTAETEVG

Sequences:

>Translated_529_residues
MSLIGKFATVGTATLGSRIFGFLRETLMAAAVGTGPVADAFNAAFRFPNTFRRLFAEGAFNSAFVPLFAKEIEANGMEGA
RRFSEEVFGVLFTVLLALTILMELSMPFIVRTVIAPGFLEDPVKFDNTVRLATIMFPYLACMSLAAMMGGMLNSLHRYFA
AAIAPVFLNIILIGVLALAWWKNYDPLQVGYALSWGVMAAGLVQLAIVWIAVRNAGMRIGLRRPRLTKNVQRLLVLALPA
AITGGITQINLLINTNIASAGEGVISSLAYADRIYQLPLGVVGIAVATVLLPELARALRGGHMVEAGSLQNRSVEFVLFL
TLPAAAALLVMAEPIVRFLYERGNFSPSATITVAQILGIYGLGLPAFVLIKAFIPGFFAREDTRTPMIFAAVSVVVNVSL
ALTLFPRLGGPGIAIAEITAGWVNAALLFGMLLWRGHWHVDIPLLTRIPRLLLAAALMAGFVHYALTWLSFELSSASSIF
VRAGTIMGLVFTAMLVYFVLAFVSGGADIGMVKRAVRKRGKKTAETEVG
>Mature_528_residues
SLIGKFATVGTATLGSRIFGFLRETLMAAAVGTGPVADAFNAAFRFPNTFRRLFAEGAFNSAFVPLFAKEIEANGMEGAR
RFSEEVFGVLFTVLLALTILMELSMPFIVRTVIAPGFLEDPVKFDNTVRLATIMFPYLACMSLAAMMGGMLNSLHRYFAA
AIAPVFLNIILIGVLALAWWKNYDPLQVGYALSWGVMAAGLVQLAIVWIAVRNAGMRIGLRRPRLTKNVQRLLVLALPAA
ITGGITQINLLINTNIASAGEGVISSLAYADRIYQLPLGVVGIAVATVLLPELARALRGGHMVEAGSLQNRSVEFVLFLT
LPAAAALLVMAEPIVRFLYERGNFSPSATITVAQILGIYGLGLPAFVLIKAFIPGFFAREDTRTPMIFAAVSVVVNVSLA
LTLFPRLGGPGIAIAEITAGWVNAALLFGMLLWRGHWHVDIPLLTRIPRLLLAAALMAGFVHYALTWLSFELSSASSIFV
RAGTIMGLVFTAMLVYFVLAFVSGGADIGMVKRAVRKRGKKTAETEVG

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=433, Percent_Identity=33.9491916859122, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 56892; Mature: 56760

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIGKFATVGTATLGSRIFGFLRETLMAAAVGTGPVADAFNAAFRFPNTFRRLFAEGAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCC
NSAFVPLFAKEIEANGMEGARRFSEEVFGVLFTVLLALTILMELSMPFIVRTVIAPGFLE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
DPVKFDNTVRLATIMFPYLACMSLAAMMGGMLNSLHRYFAAAIAPVFLNIILIGVLALAW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKNYDPLQVGYALSWGVMAAGLVQLAIVWIAVRNAGMRIGLRRPRLTKNVQRLLVLALPA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
AITGGITQINLLINTNIASAGEGVISSLAYADRIYQLPLGVVGIAVATVLLPELARALRG
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GHMVEAGSLQNRSVEFVLFLTLPAAAALLVMAEPIVRFLYERGNFSPSATITVAQILGIY
CCEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLGLPAFVLIKAFIPGFFAREDTRTPMIFAAVSVVVNVSLALTLFPRLGGPGIAIAEITA
HCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
GWVNAALLFGMLLWRGHWHVDIPLLTRIPRLLLAAALMAGFVHYALTWLSFELSSASSIF
HHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VRAGTIMGLVFTAMLVYFVLAFVSGGADIGMVKRAVRKRGKKTAETEVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLIGKFATVGTATLGSRIFGFLRETLMAAAVGTGPVADAFNAAFRFPNTFRRLFAEGAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCC
NSAFVPLFAKEIEANGMEGARRFSEEVFGVLFTVLLALTILMELSMPFIVRTVIAPGFLE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
DPVKFDNTVRLATIMFPYLACMSLAAMMGGMLNSLHRYFAAAIAPVFLNIILIGVLALAW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKNYDPLQVGYALSWGVMAAGLVQLAIVWIAVRNAGMRIGLRRPRLTKNVQRLLVLALPA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
AITGGITQINLLINTNIASAGEGVISSLAYADRIYQLPLGVVGIAVATVLLPELARALRG
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GHMVEAGSLQNRSVEFVLFLTLPAAAALLVMAEPIVRFLYERGNFSPSATITVAQILGIY
CCEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLGLPAFVLIKAFIPGFFAREDTRTPMIFAAVSVVVNVSLALTLFPRLGGPGIAIAEITA
HCCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
GWVNAALLFGMLLWRGHWHVDIPLLTRIPRLLLAAALMAGFVHYALTWLSFELSSASSIF
HHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VRAGTIMGLVFTAMLVYFVLAFVSGGADIGMVKRAVRKRGKKTAETEVG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 11274131 [H]