Click here to switch to the map view.

The map label for this gene is cycJ

Identifier: 15888317

GI number: 15888317

Start: 962869

End: 963366

Strand: Direct

Name: cycJ

Synonym: Atu0974

Alternate gene names: 15888317

Gene position: 962869-963366 (Clockwise)

Preceding gene: 15888316

Following gene: 15888318

Centisome position: 33.88

GC content: 63.65

Gene sequence:

>498_bases
ATGACCCGCAAACAGAAACGTCTGGCGATCATCGGCGGCGGCATGAGCTTCATCGTCGCGGCCGTGCTGCTGGTCATGTT
CGCCTTTGGCCAGTCGATCGCCTATTTCTACATGCCTGCCGATCTGGAAAAGACGCCGGTCAATCCCGGCACCCGCATCC
GCCTTGGCGGGCTGGTGGCGGAAGGTTCGATCAAGCGCGGCGAGGGCCGTACGGTCAGCTTCACGGTGACGGATGGCGAA
GCCAAGGTGCCGGTCAGTTATACCGGCATCCTGCCCGATCTCTTCCGCGAAGGGCAGGGCGTGGTGACCGAAGGCATGTT
CGACGCCGCCACCCATGGTTTCGTGGCCGACAGCGTTCTCGCCAAACATGACGAGAACTATATGCCCAAGGAAGTGGCCG
ACCGGCTGAAGGACAAGGGCCTGTGGCAGCAGGGCGCTGAGGGAGCGGCACCCGCCGCCAGCGCCGCCTCAGGCGACAAG
ACCGGAGCGACGAAATGA

Upstream 100 bases:

>100_bases
AGGGCAGGCAGCTTCTGGCGCTGGCGAAGGAATTGGGCGTTTCCGCCGGACCGATCCGCATGGATGGGCAAAAGGATTCT
GCGCCGCAGGGAGTGACGCA

Downstream 100 bases:

>100_bases
TCAACGAGATCGGCCATTATGTCCTGGTTTTGGCGCTCGGTGTTGGGCTGATCGTCTCGACGCTGCCTGTTATCGGCGCG
CGCCGCAACGATCGGGCACT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVAEGSIKRGEGRTVSFTVTDGE
AKVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVLAKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDK
TGATK

Sequences:

>Translated_165_residues
MTRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVAEGSIKRGEGRTVSFTVTDGE
AKVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVLAKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDK
TGATK
>Mature_164_residues
TRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVAEGSIKRGEGRTVSFTVTDGEA
KVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVLAKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDKT
GATK

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=137, Percent_Identity=43.7956204379562, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_AGRT5 (Q8UGR1)

Other databases:

- EMBL:   AE007869
- PIR:   AF2696
- PIR:   F97478
- RefSeq:   NP_353998.1
- ProteinModelPortal:   Q8UGR1
- SMR:   Q8UGR1
- STRING:   Q8UGR1
- GeneID:   1133012
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0974
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- PhylomeDB:   Q8UGR1
- ProtClustDB:   PRK13254
- BioCyc:   ATUM176299-1:ATU0974-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 17426; Mature: 17295

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: BINDING 123-123

Signals:

None

Transmembrane regions:

HASH(0xcfe8e6c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVA
CCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEEEE
EGSIKRGEGRTVSFTVTDGEAKVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVL
CCCCCCCCCCEEEEEEECCCEECCEEECCCCHHHHHCCCCCEECCHHHHHHCCHHHHHHH
AKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDKTGATK
HHCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
TRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVA
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEEEE
EGSIKRGEGRTVSFTVTDGEAKVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVL
CCCCCCCCCCEEEEEEECCCEECCEEECCCCHHHHHCCCCCEECCHHHHHHCCHHHHHHH
AKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDKTGATK
HHCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194