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The map label for this gene is ywbI [H]

Identifier: 39995376

GI number: 39995376

Start: 273393

End: 274316

Strand: Direct

Name: ywbI [H]

Synonym: GSU0266

Alternate gene names: 39995376

Gene position: 273393-274316 (Clockwise)

Preceding gene: 39995366

Following gene: 39995377

Centisome position: 7.17

GC content: 58.66

Gene sequence:

>924_bases
ATGGATATCCGCCAGTTGCAGTTTTTCGTCGCAATCGTCAGGTTCGGCAGCTTCACCAAGGCCGCGGAGCGGCTGCGCGT
GGCTCAGCCGGCCGTGAGCATGGCCATGAAGAGGCTTGAGGAGGAGCTTGACCTTGTGCTCTTCAACCGGCAGGAGCGGA
AAGTGTCTCTGACCGCCGAAGGCGAGATCTTTCTGCGGCATGCGGAGAAGATCCTGGAGGAAGTGGCGTCGACGGAAACG
GAAATGGAGGAGTTGCGCGGTCTTGCCAAGGGCGAGGTGCGGGTGGGGATACCCCCCATGATGAGCGCCTACTTTTTTCC
GCAGATCATCCGGGACTTCTCCAACCGCTATCCGGAGCTGCACCTGAGCGTGTCCGGCGAAGGAGCTTCAAAGATCCAGA
AGATGATCCTCGATGGGGAACTCGACATGGGTGTCATTGCTGGCGCGAGTTTTCCCGACACGCTCGAGTTGCGGAGATTC
CTGCGGGAAGAGGTGATCGTCTGCGTACCCAAGAACCACCACCTGGCGGAGATGGAACGTCTTCCGCTGCAGGAATTCGC
CCGCCATCCCCTGATTTTCTACAAGGAAGGGTACTACCTGCGGGAGCTCGTTTTCGACGTCATGAGAGGGGCGGGGCTCA
ATCCGGCCATCAGGTTCGAGACCAATCTCTACACCCTGGTCAAGTCGCTCATCCGGAAAGGGATGGGCATTTCGGTTTTC
TTGAGAATGGTGGTTGAGGAAGACGACGATCTGGAGGCGATTCCCCTGGACCCGCCCCTGTACCTGGATCTCCAGATCGC
CTGGAAAAAATACGGTTATCTGTCGCGGGCAAACCGTGCGTTTGTTGATTTTCTGCTGGAGCAGAGCGCCAGGGCGCATC
AACCGGTCGGCTCGTGTCCCGCGCGGTTGGTTCCTGCTGGTTGA

Upstream 100 bases:

>100_bases
CGACATTGTCAGATATAATCAAGATAGCAGTGGTCGAAATATAAATAAAATATATTATAGTTATGAATTGCATAACTTAT
GTTTATTCAAGGGCCCGGCT

Downstream 100 bases:

>100_bases
AGATGGCTTCCCGCGTACACCCCTCTTGCCTTTTCGGCCCATTTCCTCTTTGGCCCGGCCCCTTGGTAGGCGGCCATCGA
CACGATGCGCGGCGCCGTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDIRQLQFFVAIVRFGSFTKAAERLRVAQPAVSMAMKRLEEELDLVLFNRQERKVSLTAEGEIFLRHAEKILEEVASTET
EMEELRGLAKGEVRVGIPPMMSAYFFPQIIRDFSNRYPELHLSVSGEGASKIQKMILDGELDMGVIAGASFPDTLELRRF
LREEVIVCVPKNHHLAEMERLPLQEFARHPLIFYKEGYYLRELVFDVMRGAGLNPAIRFETNLYTLVKSLIRKGMGISVF
LRMVVEEDDDLEAIPLDPPLYLDLQIAWKKYGYLSRANRAFVDFLLEQSARAHQPVGSCPARLVPAG

Sequences:

>Translated_307_residues
MDIRQLQFFVAIVRFGSFTKAAERLRVAQPAVSMAMKRLEEELDLVLFNRQERKVSLTAEGEIFLRHAEKILEEVASTET
EMEELRGLAKGEVRVGIPPMMSAYFFPQIIRDFSNRYPELHLSVSGEGASKIQKMILDGELDMGVIAGASFPDTLELRRF
LREEVIVCVPKNHHLAEMERLPLQEFARHPLIFYKEGYYLRELVFDVMRGAGLNPAIRFETNLYTLVKSLIRKGMGISVF
LRMVVEEDDDLEAIPLDPPLYLDLQIAWKKYGYLSRANRAFVDFLLEQSARAHQPVGSCPARLVPAG
>Mature_307_residues
MDIRQLQFFVAIVRFGSFTKAAERLRVAQPAVSMAMKRLEEELDLVLFNRQERKVSLTAEGEIFLRHAEKILEEVASTET
EMEELRGLAKGEVRVGIPPMMSAYFFPQIIRDFSNRYPELHLSVSGEGASKIQKMILDGELDMGVIAGASFPDTLELRRF
LREEVIVCVPKNHHLAEMERLPLQEFARHPLIFYKEGYYLRELVFDVMRGAGLNPAIRFETNLYTLVKSLIRKGMGISVF
LRMVVEEDDDLEAIPLDPPLYLDLQIAWKKYGYLSRANRAFVDFLLEQSARAHQPVGSCPARLVPAG

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=29.8611111111111, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=28.1879194630872, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=26.0536398467433, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=28.1786941580756, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=26.8965517241379, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=24.7967479674797, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=24.2214532871972, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=25.3472222222222, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788296, Length=282, Percent_Identity=26.241134751773, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=176, Percent_Identity=28.9772727272727, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789204, Length=239, Percent_Identity=24.6861924686192, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081904, Length=202, Percent_Identity=28.7128712871287, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787806, Length=301, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=32.1917808219178, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=31.2925170068027, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789639, Length=172, Percent_Identity=28.4883720930233, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=23.75, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786508, Length=148, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082132, Length=169, Percent_Identity=31.3609467455621, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=21.8623481781377, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787949, Length=172, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786713, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=142, Percent_Identity=28.8732394366197, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787589, Length=159, Percent_Identity=28.9308176100629, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787128, Length=129, Percent_Identity=25.5813953488372, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1789440, Length=193, Percent_Identity=25.9067357512953, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35064; Mature: 35064

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRQLQFFVAIVRFGSFTKAAERLRVAQPAVSMAMKRLEEELDLVLFNRQERKVSLTAE
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEC
GEIFLRHAEKILEEVASTETEMEELRGLAKGEVRVGIPPMMSAYFFPQIIRDFSNRYPEL
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCEE
HLSVSGEGASKIQKMILDGELDMGVIAGASFPDTLELRRFLREEVIVCVPKNHHLAEMER
EEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHHHC
LPLQEFARHPLIFYKEGYYLRELVFDVMRGAGLNPAIRFETNLYTLVKSLIRKGMGISVF
CCHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCHHHH
LRMVVEEDDDLEAIPLDPPLYLDLQIAWKKYGYLSRANRAFVDFLLEQSARAHQPVGSCP
HHHHHCCCCCCEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARLVPAG
CCCCCCC
>Mature Secondary Structure
MDIRQLQFFVAIVRFGSFTKAAERLRVAQPAVSMAMKRLEEELDLVLFNRQERKVSLTAE
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEC
GEIFLRHAEKILEEVASTETEMEELRGLAKGEVRVGIPPMMSAYFFPQIIRDFSNRYPEL
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCEE
HLSVSGEGASKIQKMILDGELDMGVIAGASFPDTLELRRFLREEVIVCVPKNHHLAEMER
EEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHHHC
LPLQEFARHPLIFYKEGYYLRELVFDVMRGAGLNPAIRFETNLYTLVKSLIRKGMGISVF
CCHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCHHHH
LRMVVEEDDDLEAIPLDPPLYLDLQIAWKKYGYLSRANRAFVDFLLEQSARAHQPVGSCP
HHHHHCCCCCCEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARLVPAG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]