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The map label for this gene is nreC [H]

Identifier: 39995364

GI number: 39995364

Start: 262990

End: 263637

Strand: Direct

Name: nreC [H]

Synonym: GSU0254

Alternate gene names: 39995364

Gene position: 262990-263637 (Clockwise)

Preceding gene: 39995363

Following gene: 39995365

Centisome position: 6.9

GC content: 59.1

Gene sequence:

>648_bases
ATGGTGATCAAGGTTCTCATTGCCGATGACCATGCCGTCGTAAGGGACGGACTGACCATGATTCTCGAATCCCAGAGCGA
TATTGCCGTGATCGGTCAGGCCGGCGACGGGCGCGAGGCGATAGCGATGGCCGAGTCGCTTAAGCCCAACGTGGTGGTTA
TGGACATTACCATGCCGGAACTGAACGGCATCGAAGCCGCCCGCCTGATTGCCAGAGAGCAGCCGGCGACAAAAATCGTC
ATTCTTTCCATGCACGACACCCTTGAGCACGTCTACCGCGCGCTCCAGGCCGGCGCGCGGGGGTATCTCCTGAAGGAATC
GGCAGGTGCCGAGGTCACCGATGCAGTGCGAACGGTCATGCGGGGGCACCGCTATTTCGGCAGAGGGAGTCGGCTGCCGT
CCGACATGCACCGCTCCGCCTGCGCCGATCTCCCGAAAAGTCCCCTCGACAGCCTGAGCCAGCGGGAGCGGGAGGTCCTG
CAGCTGGTAGTCGAGGGGAAGAAAAGCTCTGAGATTGCTGAAATCCTTTCCCTTTCACCCAAAAGCATCGAAACCTACCG
CAGCAGGCTGATGATTAAGCTCGGTATCACCAATATCCCTTCGCTGGTCAAATTTGCCCTTCTACACGGCGTTACCCCCG
CAAAATAG

Upstream 100 bases:

>100_bases
CATGCGCGAGCGGGCTGAACTGATCGGCGGGACGTTCCGGCTGAATACCGCGCCGGGCAAAGGTACGGTACTGACTGTTG
AAATTGACGAGGGTTCGTAG

Downstream 100 bases:

>100_bases
TCTTTTCACTGTTTGAGTCAAACATTCCTGACAGACTGACGACGTTATTTCGGATATTTACTGTCGTTGGGCGCCTATCC
TTTTGTTCATACCGCGGGAA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MVIKVLIADDHAVVRDGLTMILESQSDIAVIGQAGDGREAIAMAESLKPNVVVMDITMPELNGIEAARLIAREQPATKIV
ILSMHDTLEHVYRALQAGARGYLLKESAGAEVTDAVRTVMRGHRYFGRGSRLPSDMHRSACADLPKSPLDSLSQREREVL
QLVVEGKKSSEIAEILSLSPKSIETYRSRLMIKLGITNIPSLVKFALLHGVTPAK

Sequences:

>Translated_215_residues
MVIKVLIADDHAVVRDGLTMILESQSDIAVIGQAGDGREAIAMAESLKPNVVVMDITMPELNGIEAARLIAREQPATKIV
ILSMHDTLEHVYRALQAGARGYLLKESAGAEVTDAVRTVMRGHRYFGRGSRLPSDMHRSACADLPKSPLDSLSQREREVL
QLVVEGKKSSEIAEILSLSPKSIETYRSRLMIKLGITNIPSLVKFALLHGVTPAK
>Mature_215_residues
MVIKVLIADDHAVVRDGLTMILESQSDIAVIGQAGDGREAIAMAESLKPNVVVMDITMPELNGIEAARLIAREQPATKIV
ILSMHDTLEHVYRALQAGARGYLLKESAGAEVTDAVRTVMRGHRYFGRGSRLPSDMHRSACADLPKSPLDSLSQREREVL
QLVVEGKKSSEIAEILSLSPKSIETYRSRLMIKLGITNIPSLVKFALLHGVTPAK

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=38.6046511627907, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=36.0406091370558, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=30.9859154929577, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=28.8659793814433, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=27.8048780487805, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=28.7037037037037, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=29.3478260869565, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=36.5384615384615, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23433; Mature: 23433

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKVLIADDHAVVRDGLTMILESQSDIAVIGQAGDGREAIAMAESLKPNVVVMDITMPE
CEEEEEEECCHHHHHHCHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCC
LNGIEAARLIAREQPATKIVILSMHDTLEHVYRALQAGARGYLLKESAGAEVTDAVRTVM
CCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RGHRYFGRGSRLPSDMHRSACADLPKSPLDSLSQREREVLQLVVEGKKSSEIAEILSLSP
HHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
KSIETYRSRLMIKLGITNIPSLVKFALLHGVTPAK
HHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVIKVLIADDHAVVRDGLTMILESQSDIAVIGQAGDGREAIAMAESLKPNVVVMDITMPE
CEEEEEEECCHHHHHHCHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCC
LNGIEAARLIAREQPATKIVILSMHDTLEHVYRALQAGARGYLLKESAGAEVTDAVRTVM
CCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RGHRYFGRGSRLPSDMHRSACADLPKSPLDSLSQREREVLQLVVEGKKSSEIAEILSLSP
HHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
KSIETYRSRLMIKLGITNIPSLVKFALLHGVTPAK
HHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA