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The map label for this gene is pimB [H]

Identifier: 38234721

GI number: 38234721

Start: 2254468

End: 2255622

Strand: Reverse

Name: pimB [H]

Synonym: DIP2178

Alternate gene names: 38234721

Gene position: 2255622-2254468 (Counterclockwise)

Preceding gene: 38234723

Following gene: 38234718

Centisome position: 90.64

GC content: 59.13

Gene sequence:

>1155_bases
GTGGGGCGAGCGCCTACGATGGAGGCTGATATGAGGATTTTGTTACTCTGCTGGCGCGACACCACCCACCCCCAAGGCGG
TGGCAGTGAGCGCTACTTGGAGCACATTGCAAAGTATTTGGTGGCGTCGGGGCATGAGGTGATTTTTCGGACGGCGCGCC
ATACGGATGCGTCGCGACGCGCCGTGCGTGACGGGGTGGAGTACCAGTACGCGGGCGGCAAGTATTCGGTTTATGTTCGG
GCTGCGGTGGCGCAGCTTATGGGGCGGCTGGGGGTTGGTCGGCTGCGTGGGGTGGATGTGGCGGTGGATACCCAAAATGG
TATTCCGTTTTTTGCGCGGGTGTTTTCGGGCGTGCCGACGATCCTGCTTACCCACCATTGTCATCGCCGGCAGTGGGATG
TGGCTGGTCCGCTTATTGCGCGCTTGGGCTGGTTTATTGAGTCGAAGGTGTCCCCGTGGGTGCATCGGGGTGTGCGGTAT
GTGACGGTGTCGGAGCCGAGTCGCGACGAGCTGGTTGAACTGGGCGTTCCTGCAGGCAACATTACTATTGTGCGCAATGG
AATTGATGATCCTCCGGCTCCAATGAATCTGCCGCCGGTAACGCGACCCCACCTTGTCACCTTGTCGCGGTTAGTGCCGC
ATAAGCAGATCGAGCATGCCATCGATGTAGTGCGCGAACTCGATGGGGTGGTGCTCGACATCATTGGTTCAGGTTGGTGG
GAGCCGCAACTACGAGAATATGCACGTGATGTGGCCGATCGTGTGATTTTCCATGGTCAGGTGGCAGAAGATCACAAGCA
TGCGTTGTTGGCGCAGGCTGCCGTACATGTGATGCCCTCGCGGAAAGAGGGGTGGGGGCTCGCCGTAATTGAGGCTGGTC
AGCACGGGGTGCCTACTGTTGGCTATTCCCATTCTGGTGGCCTTAGGGATTCGGTGCGTGGCGGTGGGGTGTTGGTGGAA
ACTCCCGCTCAGCTTACGTGCGCTATCCGCCAGTTGCTCGCGGACCAACGCTATCGCGATGAGTTGGGGCGACGTGCTTA
TGGTTTCGCTTCAACGTTTTCGTGGGAAGATACTGGTCGCGAGTTTCTGCGCGTGATTGCGCAGCCGCAGATTCCAGCCG
CAGCCCACAGTACTAAGCAGCCCAATCCGAGATAA

Upstream 100 bases:

>100_bases
TGCTCGTACTTGAAGCTGCGCAGGAGGCGGAGGGATCGGCGCAAAGTGGCGAAATGCATGCCCTTTATCTTGGCACAATC
CCTGCAAAAACGGGCTGGTT

Downstream 100 bases:

>100_bases
AAACCAGCGGTTCGCTGGGGCGTGGAATCGGCGATGGGGGTGAACTTGCCGTGGTCGATCACAGCTGTGATTCCTTGTTC
CCGCAGGTAGTTATGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MGRAPTMEADMRILLLCWRDTTHPQGGGSERYLEHIAKYLVASGHEVIFRTARHTDASRRAVRDGVEYQYAGGKYSVYVR
AAVAQLMGRLGVGRLRGVDVAVDTQNGIPFFARVFSGVPTILLTHHCHRRQWDVAGPLIARLGWFIESKVSPWVHRGVRY
VTVSEPSRDELVELGVPAGNITIVRNGIDDPPAPMNLPPVTRPHLVTLSRLVPHKQIEHAIDVVRELDGVVLDIIGSGWW
EPQLREYARDVADRVIFHGQVAEDHKHALLAQAAVHVMPSRKEGWGLAVIEAGQHGVPTVGYSHSGGLRDSVRGGGVLVE
TPAQLTCAIRQLLADQRYRDELGRRAYGFASTFSWEDTGREFLRVIAQPQIPAAAHSTKQPNPR

Sequences:

>Translated_384_residues
MGRAPTMEADMRILLLCWRDTTHPQGGGSERYLEHIAKYLVASGHEVIFRTARHTDASRRAVRDGVEYQYAGGKYSVYVR
AAVAQLMGRLGVGRLRGVDVAVDTQNGIPFFARVFSGVPTILLTHHCHRRQWDVAGPLIARLGWFIESKVSPWVHRGVRY
VTVSEPSRDELVELGVPAGNITIVRNGIDDPPAPMNLPPVTRPHLVTLSRLVPHKQIEHAIDVVRELDGVVLDIIGSGWW
EPQLREYARDVADRVIFHGQVAEDHKHALLAQAAVHVMPSRKEGWGLAVIEAGQHGVPTVGYSHSGGLRDSVRGGGVLVE
TPAQLTCAIRQLLADQRYRDELGRRAYGFASTFSWEDTGREFLRVIAQPQIPAAAHSTKQPNPR
>Mature_383_residues
GRAPTMEADMRILLLCWRDTTHPQGGGSERYLEHIAKYLVASGHEVIFRTARHTDASRRAVRDGVEYQYAGGKYSVYVRA
AVAQLMGRLGVGRLRGVDVAVDTQNGIPFFARVFSGVPTILLTHHCHRRQWDVAGPLIARLGWFIESKVSPWVHRGVRYV
TVSEPSRDELVELGVPAGNITIVRNGIDDPPAPMNLPPVTRPHLVTLSRLVPHKQIEHAIDVVRELDGVVLDIIGSGWWE
PQLREYARDVADRVIFHGQVAEDHKHALLAQAAVHVMPSRKEGWGLAVIEAGQHGVPTVGYSHSGGLRDSVRGGGVLVET
PAQLTCAIRQLLADQRYRDELGRRAYGFASTFSWEDTGREFLRVIAQPQIPAAAHSTKQPNPR

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 42543; Mature: 42412

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAPTMEADMRILLLCWRDTTHPQGGGSERYLEHIAKYLVASGHEVIFRTARHTDASRR
CCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEEEHHCCCHHHH
AVRDGVEYQYAGGKYSVYVRAAVAQLMGRLGVGRLRGVDVAVDTQNGIPFFARVFSGVPT
HHHCCCCEEECCCEEEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHCCCCH
ILLTHHCHRRQWDVAGPLIARLGWFIESKVSPWVHRGVRYVTVSEPSRDELVELGVPAGN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCHHHHHEECCCCCC
ITIVRNGIDDPPAPMNLPPVTRPHLVTLSRLVPHKQIEHAIDVVRELDGVVLDIIGSGWW
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCC
EPQLREYARDVADRVIFHGQVAEDHKHALLAQAAVHVMPSRKEGWGLAVIEAGQHGVPTV
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC
GYSHSGGLRDSVRGGGVLVETPAQLTCAIRQLLADQRYRDELGRRAYGFASTFSWEDTGR
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHH
EFLRVIAQPQIPAAAHSTKQPNPR
HHHHHHCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
GRAPTMEADMRILLLCWRDTTHPQGGGSERYLEHIAKYLVASGHEVIFRTARHTDASRR
CCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEEEHHCCCHHHH
AVRDGVEYQYAGGKYSVYVRAAVAQLMGRLGVGRLRGVDVAVDTQNGIPFFARVFSGVPT
HHHCCCCEEECCCEEEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHCCCCH
ILLTHHCHRRQWDVAGPLIARLGWFIESKVSPWVHRGVRYVTVSEPSRDELVELGVPAGN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCHHHHHEECCCCCC
ITIVRNGIDDPPAPMNLPPVTRPHLVTLSRLVPHKQIEHAIDVVRELDGVVLDIIGSGWW
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCC
EPQLREYARDVADRVIFHGQVAEDHKHALLAQAAVHVMPSRKEGWGLAVIEAGQHGVPTV
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC
GYSHSGGLRDSVRGGGVLVETPAQLTCAIRQLLADQRYRDELGRRAYGFASTFSWEDTGR
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHH
EFLRVIAQPQIPAAAHSTKQPNPR
HHHHHHCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]