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The map label for this gene is irp2 [H]

Identifier: 38234704

GI number: 38234704

Start: 2229393

End: 2234573

Strand: Reverse

Name: irp2 [H]

Synonym: DIP2161

Alternate gene names: 38234704

Gene position: 2234573-2229393 (Counterclockwise)

Preceding gene: 38234712

Following gene: 38234703

Centisome position: 89.79

GC content: 59.22

Gene sequence:

>5181_bases
ATGAACACCACCACCACAACCGACACCATTACCGAAATTCTCACCGCCATATACGGCCCCGTCGACCCCCAGCAATCCCT
CTCGCACCTCGGCATCGACTCCATGACCGCGGTACGCCTCCAAAGAGAAATCCACCACGCCACCGGCATATACCTCCCAC
TTATCACCTTTCTTGGTGATGCCACCGTGGCCACACTCGTCCGCGCAGTCGACAACGCCGAACCAGCCGCGCTGGAAACG
TCGACACGCACAATCCCCACCAACGGGCGCACCATGACCCCCGTCCAAGCAACCTACTGGGTAGGGCGACAACCCGACTA
CGCCCTCGGCGGAATCGCCACGCGCTTTTACATGGAACACGACATCACCATCGACGGCCCCATGGACGAATGGATCGACG
CCCTACGCCGCAGCTGGAACACAGTGGTCCAACGCCACGGGATGCTTCGCGCCACCGTCGACCGCGACGGCAAAATCTCC
ATCGCCGATACCGTCACCGAACATCCCCTCCCCGTCCACAACGCCGATCACGCGGCGGAAGTGCGAGAACGCCTCGCCCA
CCGCACCGCCGACCTTGGCACATGGCCTGTCCATGACATAGAACTCACCACGATAACCGCCACCACCGTGCGCATTCACT
GCGGATTCGACGTTATCCTGATCGACTACCCCAGCATTATGCGCGTCCTCAACGACTGGGGGCGAGCACTCGCCGGCTAC
GACCTCGGCACCGAAGACACAAGCTTTAGCGACCTCATCGCCCAAGGAATAGCCGAACCATGCCCCAGCGACGAAGCCTA
CTGGCGCGAACGCGCCCCACGCCTGCTACCAGGGCCCCTCGACCTAGCCGAGATGACTTACGACGCCGCCACGACCCCAG
AATTCCACCGGCACACCCGCACCATCGCGGCTCAGCAGTGGAAGCAGTTCGTCGATAATGCGCACGCACACGGCACCAAC
GCCTCCAGCGCACTACTGGCAGTTGCCGCCCACAGTCTGCGGCATGTTGGCCCACGGCGCTCCTTCACCCTCGGCGCTAC
CTTCTTTTCCCCCGACGTGCTCGAACACGGCCCCGTTGGCGATTTCACCCGCACCGGTGTCGTGGAACTGCCCGACACCG
CAGACACCTTTGCCCAGCAAGCCAGCGCAGCGCAGCACGAACTTTGGGAAGCCTTCGACCATGCCTCGGTGACCTCTGCT
GACATCATGCGCTGGCGCAATAGCGACACAACGGGGCAGGCATTGCCGGACTATCCCGTGGTGTTTACCTCCGCCTTAGG
TCACGGCGACAGTACCGACTGGCCAGGTGTGATGACGTGGGGTGTGAGCCAAACCCCGCAAGTGCTCATGGACTTATTGC
ACTGGGAATCAGATGGTGACTTAGTACTCGCCTGGGATTGCGTCGACGCTGCACTACCGGAGAACTTCGCTGACAATGCC
ATCGATATTGCCTATGCGGTGATCCAGCAGCTCACCAACCCCGCGGTGTGGACAGACCCAACTGTGGTGGCTGACCCCTG
GTTGCGCATGCCTGGACCAATGGAACGCATCGGCGAAAGCGAGCTTATCGACGCCCCACTGCGCGCCCAATACGAGGCAG
CACCCGAGGCTCGCGCTGTTATTGCAGGGGAGCAATCGTGGACTCGCGCCGAACTAGACCACCATAGTGAACGCCTTGCT
GCGGCTGTGGCCCGTGCTGCCCATGACCATGATGTAGTCCGTGCGGATGCGCCGGTTCTTGTGATGATGCAGAAATCCTG
CATGCAGGTCGCTGCGGTCTGTGCGGTTGTTCGTGCAGGTTTTGCCTATATTCCGGTGGACCCCAGCTGGCCTATGGAAC
GCGTGCAATCAGTCATGCAGCGATCGGGTGCCGTTGTGTGCTTAGCGGATGAGGGCGTGGCGATCCCCGAGGGATTGCAC
CGAATCCCACTATCTGAGCAAGGCGCGGAGGCTACCGGTTATACGGGCCGGCAATCACAGCCCGAAGATCTTGCCTACGT
GATTTTTACCTCCGGTTCTACGGGGCAACCCAAGGGTGTGGCGATCGAGCACCGCGCCGCACGGACCACCATTGATGATA
TCAACCAGCGCTTTGAGATCACCGATACCGATGTGGTTCTTGGTTTATCAGCGCTGAGCTTTGATCTATCAGTGTGGGAC
ATTTTCGGTGGTCTTGGCGCTGGCGCTACGGTGGTGCTGCCGGAAGAAGATCGGCTTCGTGATCCTTCCTATTGGCTTGA
TCTGTGTGATCGTCACGAGATTACCGTGTGGAATTCCGCGCCACCGTTGTTAGAAATGCTCGTGGATTATGCGGAGATTG
ATCCCGAAGCTGCTGCGCATGCGCTGCGTAACCTGCGGATGGTCATGCTGTCTGGCGACTGGATTCCGGTGACCTTGCCT
CGTCGGCTTAAAGAGCTTGCGCCCAACGCCACCGTGATGAGCTTGGGTGGTGCCACCGAGGCGTCGATCTGGTCTATCTG
TCACCGCACAAGCGATGCAGACGAACATGGGCCATCGATCCCTTATGGGCGTGCGCTGCGGGGTCAGTGGTTCCGCATCC
TCGATACCGAGGGCGTACCAGTTCCACTAGGAACACCTGGTATTTTGCACATCGGTGGTCACGGTGTTGCCCGCGGCTAT
CTGGGGGATCCGGAGCGTACCGCCGAGCGTTTTTGCGAGCATCCCCGTTTGGGTGAGCGGCTTTATAACACGGGCGATGA
AGGCATGTGGTTGCCTAATGGTGAGATCCGATTCTTGGGGCGCGTGGACCGACAGGTAAAAATCAATGGTTTTCGTATTG
AGTTAGGTGAGGTCGACGCAGCTCTGGCACGGTGTGCCAGTGTGAAATCCGCGATTTCGGCAGCGCCGCAGGATGCCTCG
GGGCGCAAGCGCCTCCTCGGACATGTGGTTCCTACGCAGCCGGAGCGTTTCGACGACTCCGTGTTGCGTCGCGAGTTAGC
AGAGCACTTGCCGTCTTATATGATTCCTTCTCGTTTTGTGGTGCACGATCATCTGCCGGTCACCGATAACGGCAAGGTGG
ATCATAAAGCGTTGCCTAATCCGTGGTGTGCTGAAACCGCACCGGAACCGCAGGTGGAGCCAGAACCCGAAGTGCTGCCC
GAGCCTGATCGCGGTAGCGCTACCCCTGCAGAGCTGGGGATTAACTCCTTAGATATTGTGCGGTTGGCCAACCGGATTGA
AGATGCCACGGGTACGCGGCCGTCGTTAGCCACCTTGTTGAATCAGCCGTGGCAGGAGTCACTGGCGATGGTGGAGGTGC
TAGAACCGCGGCCGGCGCTAGCGTCTGAGCAGAAACCGGAATTGGTTCCAGATCGTGATCGGGAGGTCATTGATGTTGTC
GGTGCCGGAATGGCGTTAGGTGCGCGAATTCGTGCGGAGGTTCCGATAAGTGAGGAGCCGGTAGAGGATCAGTTTGTGCA
GGTGGGGCAGTGGCTTAAGCAGCTGCGTGCGGTGGTAGAGCCTGCCGGATGTATGCAGGTTACCCCGCCATCGGGAAATA
TATTGTGTGCAATTGACATCACTCCTGGTGAGAAAGCGGACGTGTCTGACCATGCACCGTTGACCCCGCTGCAGTTGGGA
TATTTGGTGGGGCGCGCGGATACCTGGCTTGGTGAGCCGGTGGCGCCGCACTATTACACCGAAGTTGAGGTGGCAGACCT
TGATGTGGTGGCGTTGCAACGAGCGCTCGATGAGGTGGTGCGGGCGCATCCGGCGCTGATGTTAGGTGTGCATGACGACG
GCAACCAAGGCTTGTCCGAGGCCCTACGGCCGCGCTTGGTGGTCACTGATCTACGGGATCATCCCGATCCAGATGGCGAG
CTGGAGCGCATTCGTGCTGTGGGGTGCGCTGGCGTTTCGGATCCGTTGGGTACCGCATGGTTCCAATTGCGTGCAACCTT
ATTACCTACAGCTGTGCGGCTGCATCTTTCCATCGATATGCTGTTTTGTGATGTCGTCGGCGCTGGGGTGTTGGTATCTG
ATCTGCAGCGTGCCTACAACGGGGAAACTCTTGAACCCGAACAGCGAGGTTTCTTGGAGTTTGCGCAGCGTGTGGCACAA
AATTTCGGTGCGCAGGTTACGGCAGGTGCCAGCGATGCCCAGCCGTTACCCTCAGTGATTGGCCCGTGGCAGCAGCCCAC
CTCGGCGCGGTTTGAGCGGATTCGTACGGAGATAACTTCGGATGTGGCTGATGAGCTTTCTCGTGCTGCAGCGACGATGG
GGGTCACCCTTGATGCGTTGATGGCGACGATCATTTCTACAACAGCCGGTGCGATTACAGGTTCTCCTGCGCAGCCTATT
GTGGCCACGGTGCTTGCGCGTCCGCGGGGTTTTGAGCGCACGGTGGGTGAGTTCACCTCGACGGTGCGTGTTGTCCCAGA
TCAAGGCGATTTTGTGGCGCGTGCGAAGTCCGCTACGCACACCTTGGTGACGGCTACTGATCGTGCTTTGCGGTGTGAGA
GTGAGCCTCGTCAGGGGTCTGCGGAGGTAACACCGATTGTGTATTCCTCGGGGCTTCATGCCGTGGGCGATCAGTCTGAG
GTTTTGGGCACGTGGGGTAAAACGATCGTTGCTCAGTCGTGGACGCCGCAGGTGCTTGTCGACGTCCAACTTTTTCGCAC
CGAGTCTGGTCTGGCACTCATCGTGGATTATGCCGTTGATGCGCTGCAGCCTGGTGCTGGTCGCGCGTTCGCCGATGGAA
TCGTTGCTGCGATGCGGCAGTGTGCGATGGGTGCTGGCATGGATTCGATATGGCCTCAGCTGCGTGTGCCTGGGCTTCGT
GCAGTGGATACGCGGTGGACTGCATTTGATGGTGATTCTGCGCCGAGTTCCACTAAGCCAGATCATCTTATCGAGGTGGA
CATTGTTGCCCATGAGCTAGGATCGGTGCTCGGAATAACGCTTGAGGCGCAGTCCTATGACAAGGGATTTTTCGATGTGG
GCGCAAGTTCCGTTGATCTGATTGCCATGCGCAATGCGCTGGTATCGCGGGGCTATTCGCTGACGCTTCTCGACGTGTTT
GCACACCCTAGTGTGCTGCAACTCGGTCGATTCATTGCCCCAGATACCCCGACTACCTCGCAGGTGACTACCGATTCTGC
TCATCAACGCGGCCACAGAAGGCGTCGTATAGCTCGTGCTTTGAATGGAGAACTCTCATGA

Upstream 100 bases:

>100_bases
CCCTCTGGAAAATATGCCCATTGTTGAAAATAATTACCACTTGCAGCGTGAGGTATATAAAAAGTGCTACATGGTAGCTG
GTTGTGGGAGGAAACATTAG

Downstream 100 bases:

>100_bases
CCACATTCGCATCAACAGACATCGCTGTGGTGGCTGCGGAATGCCGATTCCCAGGCATCCACACCATGGCTGAGCTGCAC
CAGCAACTATGTTCTGGAAC

Product: nonribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: HMWP2 [H]

Number of amino acids: Translated: 1726; Mature: 1726

Protein sequence:

>1726_residues
MNTTTTTDTITEILTAIYGPVDPQQSLSHLGIDSMTAVRLQREIHHATGIYLPLITFLGDATVATLVRAVDNAEPAALET
STRTIPTNGRTMTPVQATYWVGRQPDYALGGIATRFYMEHDITIDGPMDEWIDALRRSWNTVVQRHGMLRATVDRDGKIS
IADTVTEHPLPVHNADHAAEVRERLAHRTADLGTWPVHDIELTTITATTVRIHCGFDVILIDYPSIMRVLNDWGRALAGY
DLGTEDTSFSDLIAQGIAEPCPSDEAYWRERAPRLLPGPLDLAEMTYDAATTPEFHRHTRTIAAQQWKQFVDNAHAHGTN
ASSALLAVAAHSLRHVGPRRSFTLGATFFSPDVLEHGPVGDFTRTGVVELPDTADTFAQQASAAQHELWEAFDHASVTSA
DIMRWRNSDTTGQALPDYPVVFTSALGHGDSTDWPGVMTWGVSQTPQVLMDLLHWESDGDLVLAWDCVDAALPENFADNA
IDIAYAVIQQLTNPAVWTDPTVVADPWLRMPGPMERIGESELIDAPLRAQYEAAPEARAVIAGEQSWTRAELDHHSERLA
AAVARAAHDHDVVRADAPVLVMMQKSCMQVAAVCAVVRAGFAYIPVDPSWPMERVQSVMQRSGAVVCLADEGVAIPEGLH
RIPLSEQGAEATGYTGRQSQPEDLAYVIFTSGSTGQPKGVAIEHRAARTTIDDINQRFEITDTDVVLGLSALSFDLSVWD
IFGGLGAGATVVLPEEDRLRDPSYWLDLCDRHEITVWNSAPPLLEMLVDYAEIDPEAAAHALRNLRMVMLSGDWIPVTLP
RRLKELAPNATVMSLGGATEASIWSICHRTSDADEHGPSIPYGRALRGQWFRILDTEGVPVPLGTPGILHIGGHGVARGY
LGDPERTAERFCEHPRLGERLYNTGDEGMWLPNGEIRFLGRVDRQVKINGFRIELGEVDAALARCASVKSAISAAPQDAS
GRKRLLGHVVPTQPERFDDSVLRRELAEHLPSYMIPSRFVVHDHLPVTDNGKVDHKALPNPWCAETAPEPQVEPEPEVLP
EPDRGSATPAELGINSLDIVRLANRIEDATGTRPSLATLLNQPWQESLAMVEVLEPRPALASEQKPELVPDRDREVIDVV
GAGMALGARIRAEVPISEEPVEDQFVQVGQWLKQLRAVVEPAGCMQVTPPSGNILCAIDITPGEKADVSDHAPLTPLQLG
YLVGRADTWLGEPVAPHYYTEVEVADLDVVALQRALDEVVRAHPALMLGVHDDGNQGLSEALRPRLVVTDLRDHPDPDGE
LERIRAVGCAGVSDPLGTAWFQLRATLLPTAVRLHLSIDMLFCDVVGAGVLVSDLQRAYNGETLEPEQRGFLEFAQRVAQ
NFGAQVTAGASDAQPLPSVIGPWQQPTSARFERIRTEITSDVADELSRAAATMGVTLDALMATIISTTAGAITGSPAQPI
VATVLARPRGFERTVGEFTSTVRVVPDQGDFVARAKSATHTLVTATDRALRCESEPRQGSAEVTPIVYSSGLHAVGDQSE
VLGTWGKTIVAQSWTPQVLVDVQLFRTESGLALIVDYAVDALQPGAGRAFADGIVAAMRQCAMGAGMDSIWPQLRVPGLR
AVDTRWTAFDGDSAPSSTKPDHLIEVDIVAHELGSVLGITLEAQSYDKGFFDVGASSVDLIAMRNALVSRGYSLTLLDVF
AHPSVLQLGRFIAPDTPTTSQVTTDSAHQRGHRRRRIARALNGELS

Sequences:

>Translated_1726_residues
MNTTTTTDTITEILTAIYGPVDPQQSLSHLGIDSMTAVRLQREIHHATGIYLPLITFLGDATVATLVRAVDNAEPAALET
STRTIPTNGRTMTPVQATYWVGRQPDYALGGIATRFYMEHDITIDGPMDEWIDALRRSWNTVVQRHGMLRATVDRDGKIS
IADTVTEHPLPVHNADHAAEVRERLAHRTADLGTWPVHDIELTTITATTVRIHCGFDVILIDYPSIMRVLNDWGRALAGY
DLGTEDTSFSDLIAQGIAEPCPSDEAYWRERAPRLLPGPLDLAEMTYDAATTPEFHRHTRTIAAQQWKQFVDNAHAHGTN
ASSALLAVAAHSLRHVGPRRSFTLGATFFSPDVLEHGPVGDFTRTGVVELPDTADTFAQQASAAQHELWEAFDHASVTSA
DIMRWRNSDTTGQALPDYPVVFTSALGHGDSTDWPGVMTWGVSQTPQVLMDLLHWESDGDLVLAWDCVDAALPENFADNA
IDIAYAVIQQLTNPAVWTDPTVVADPWLRMPGPMERIGESELIDAPLRAQYEAAPEARAVIAGEQSWTRAELDHHSERLA
AAVARAAHDHDVVRADAPVLVMMQKSCMQVAAVCAVVRAGFAYIPVDPSWPMERVQSVMQRSGAVVCLADEGVAIPEGLH
RIPLSEQGAEATGYTGRQSQPEDLAYVIFTSGSTGQPKGVAIEHRAARTTIDDINQRFEITDTDVVLGLSALSFDLSVWD
IFGGLGAGATVVLPEEDRLRDPSYWLDLCDRHEITVWNSAPPLLEMLVDYAEIDPEAAAHALRNLRMVMLSGDWIPVTLP
RRLKELAPNATVMSLGGATEASIWSICHRTSDADEHGPSIPYGRALRGQWFRILDTEGVPVPLGTPGILHIGGHGVARGY
LGDPERTAERFCEHPRLGERLYNTGDEGMWLPNGEIRFLGRVDRQVKINGFRIELGEVDAALARCASVKSAISAAPQDAS
GRKRLLGHVVPTQPERFDDSVLRRELAEHLPSYMIPSRFVVHDHLPVTDNGKVDHKALPNPWCAETAPEPQVEPEPEVLP
EPDRGSATPAELGINSLDIVRLANRIEDATGTRPSLATLLNQPWQESLAMVEVLEPRPALASEQKPELVPDRDREVIDVV
GAGMALGARIRAEVPISEEPVEDQFVQVGQWLKQLRAVVEPAGCMQVTPPSGNILCAIDITPGEKADVSDHAPLTPLQLG
YLVGRADTWLGEPVAPHYYTEVEVADLDVVALQRALDEVVRAHPALMLGVHDDGNQGLSEALRPRLVVTDLRDHPDPDGE
LERIRAVGCAGVSDPLGTAWFQLRATLLPTAVRLHLSIDMLFCDVVGAGVLVSDLQRAYNGETLEPEQRGFLEFAQRVAQ
NFGAQVTAGASDAQPLPSVIGPWQQPTSARFERIRTEITSDVADELSRAAATMGVTLDALMATIISTTAGAITGSPAQPI
VATVLARPRGFERTVGEFTSTVRVVPDQGDFVARAKSATHTLVTATDRALRCESEPRQGSAEVTPIVYSSGLHAVGDQSE
VLGTWGKTIVAQSWTPQVLVDVQLFRTESGLALIVDYAVDALQPGAGRAFADGIVAAMRQCAMGAGMDSIWPQLRVPGLR
AVDTRWTAFDGDSAPSSTKPDHLIEVDIVAHELGSVLGITLEAQSYDKGFFDVGASSVDLIAMRNALVSRGYSLTLLDVF
AHPSVLQLGRFIAPDTPTTSQVTTDSAHQRGHRRRRIARALNGELS
>Mature_1726_residues
MNTTTTTDTITEILTAIYGPVDPQQSLSHLGIDSMTAVRLQREIHHATGIYLPLITFLGDATVATLVRAVDNAEPAALET
STRTIPTNGRTMTPVQATYWVGRQPDYALGGIATRFYMEHDITIDGPMDEWIDALRRSWNTVVQRHGMLRATVDRDGKIS
IADTVTEHPLPVHNADHAAEVRERLAHRTADLGTWPVHDIELTTITATTVRIHCGFDVILIDYPSIMRVLNDWGRALAGY
DLGTEDTSFSDLIAQGIAEPCPSDEAYWRERAPRLLPGPLDLAEMTYDAATTPEFHRHTRTIAAQQWKQFVDNAHAHGTN
ASSALLAVAAHSLRHVGPRRSFTLGATFFSPDVLEHGPVGDFTRTGVVELPDTADTFAQQASAAQHELWEAFDHASVTSA
DIMRWRNSDTTGQALPDYPVVFTSALGHGDSTDWPGVMTWGVSQTPQVLMDLLHWESDGDLVLAWDCVDAALPENFADNA
IDIAYAVIQQLTNPAVWTDPTVVADPWLRMPGPMERIGESELIDAPLRAQYEAAPEARAVIAGEQSWTRAELDHHSERLA
AAVARAAHDHDVVRADAPVLVMMQKSCMQVAAVCAVVRAGFAYIPVDPSWPMERVQSVMQRSGAVVCLADEGVAIPEGLH
RIPLSEQGAEATGYTGRQSQPEDLAYVIFTSGSTGQPKGVAIEHRAARTTIDDINQRFEITDTDVVLGLSALSFDLSVWD
IFGGLGAGATVVLPEEDRLRDPSYWLDLCDRHEITVWNSAPPLLEMLVDYAEIDPEAAAHALRNLRMVMLSGDWIPVTLP
RRLKELAPNATVMSLGGATEASIWSICHRTSDADEHGPSIPYGRALRGQWFRILDTEGVPVPLGTPGILHIGGHGVARGY
LGDPERTAERFCEHPRLGERLYNTGDEGMWLPNGEIRFLGRVDRQVKINGFRIELGEVDAALARCASVKSAISAAPQDAS
GRKRLLGHVVPTQPERFDDSVLRRELAEHLPSYMIPSRFVVHDHLPVTDNGKVDHKALPNPWCAETAPEPQVEPEPEVLP
EPDRGSATPAELGINSLDIVRLANRIEDATGTRPSLATLLNQPWQESLAMVEVLEPRPALASEQKPELVPDRDREVIDVV
GAGMALGARIRAEVPISEEPVEDQFVQVGQWLKQLRAVVEPAGCMQVTPPSGNILCAIDITPGEKADVSDHAPLTPLQLG
YLVGRADTWLGEPVAPHYYTEVEVADLDVVALQRALDEVVRAHPALMLGVHDDGNQGLSEALRPRLVVTDLRDHPDPDGE
LERIRAVGCAGVSDPLGTAWFQLRATLLPTAVRLHLSIDMLFCDVVGAGVLVSDLQRAYNGETLEPEQRGFLEFAQRVAQ
NFGAQVTAGASDAQPLPSVIGPWQQPTSARFERIRTEITSDVADELSRAAATMGVTLDALMATIISTTAGAITGSPAQPI
VATVLARPRGFERTVGEFTSTVRVVPDQGDFVARAKSATHTLVTATDRALRCESEPRQGSAEVTPIVYSSGLHAVGDQSE
VLGTWGKTIVAQSWTPQVLVDVQLFRTESGLALIVDYAVDALQPGAGRAFADGIVAAMRQCAMGAGMDSIWPQLRVPGLR
AVDTRWTAFDGDSAPSSTKPDHLIEVDIVAHELGSVLGITLEAQSYDKGFFDVGASSVDLIAMRNALVSRGYSLTLLDVF
AHPSVLQLGRFIAPDTPTTSQVTTDSAHQRGHRRRRIARALNGELS

Specific function: Unknown. May be involved in the nonribosomal synthesis of small peptides [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=362, Percent_Identity=29.8342541436464, Blast_Score=114, Evalue=1e-24,
Organism=Homo sapiens, GI115511026, Length=381, Percent_Identity=25.7217847769029, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI13236579, Length=398, Percent_Identity=26.6331658291457, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI28416953, Length=548, Percent_Identity=25, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI157311624, Length=518, Percent_Identity=22.3938223938224, Blast_Score=68, Evalue=6e-11,
Organism=Homo sapiens, GI157311622, Length=518, Percent_Identity=22.3938223938224, Blast_Score=68, Evalue=6e-11,
Organism=Escherichia coli, GI1786801, Length=474, Percent_Identity=33.9662447257384, Blast_Score=226, Evalue=7e-60,
Organism=Escherichia coli, GI145693145, Length=520, Percent_Identity=23.4615384615385, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=472, Percent_Identity=25, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=367, Percent_Identity=26.158038147139, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32564422, Length=367, Percent_Identity=26.158038147139, Blast_Score=93, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994690, Length=312, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71994694, Length=312, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994703, Length=312, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=430, Percent_Identity=22.093023255814, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=616, Percent_Identity=24.3506493506494, Blast_Score=149, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319699, Length=368, Percent_Identity=25.2717391304348, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648676, Length=511, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656500, Length=362, Percent_Identity=24.8618784530387, Blast_Score=71, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19922652, Length=367, Percent_Identity=23.9782016348774, Blast_Score=69, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581924, Length=370, Percent_Identity=22.4324324324324, Blast_Score=67, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013217
- InterPro:   IPR013624
- InterPro:   IPR006163
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF08242 Methyltransf_12; PF08415 NRPS; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 187548; Mature: 187548

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTTTTDTITEILTAIYGPVDPQQSLSHLGIDSMTAVRLQREIHHATGIYLPLITFLGD
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATVATLVRAVDNAEPAALETSTRTIPTNGRTMTPVQATYWVGRQPDYALGGIATRFYMEH
HHHHHHHHHHCCCCCCEEECCCCEECCCCCEECCCEEEEECCCCCCCHHHHHHEEEEEEE
DITIDGPMDEWIDALRRSWNTVVQRHGMLRATVDRDGKISIADTVTEHPLPVHNADHAAE
CCEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHH
VRERLAHRTADLGTWPVHDIELTTITATTVRIHCGFDVILIDYPSIMRVLNDWGRALAGY
HHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEEECEEEEEECCHHHHHHHHHHHHHHHCC
DLGTEDTSFSDLIAQGIAEPCPSDEAYWRERAPRLLPGPLDLAEMTYDAATTPEFHRHTR
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHH
TIAAQQWKQFVDNAHAHGTNASSALLAVAAHSLRHVGPRRSFTLGATFFSPDVLEHGPVG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHCCCCCC
DFTRTGVVELPDTADTFAQQASAAQHELWEAFDHASVTSADIMRWRNSDTTGQALPDYPV
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCC
VFTSALGHGDSTDWPGVMTWGVSQTPQVLMDLLHWESDGDLVLAWDCVDAALPENFADNA
HHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHCCCCCCCCH
IDIAYAVIQQLTNPAVWTDPTVVADPWLRMPGPMERIGESELIDAPLRAQYEAAPEARAV
HHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHCCCHHHCCCCHHHHHCCCCCCEEE
IAGEQSWTRAELDHHSERLAAAVARAAHDHDVVRADAPVLVMMQKSCMQVAAVCAVVRAG
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHCC
FAYIPVDPSWPMERVQSVMQRSGAVVCLADEGVAIPEGLHRIPLSEQGAEATGYTGRQSQ
CEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
PEDLAYVIFTSGSTGQPKGVAIEHRAARTTIDDINQRFEITDTDVVLGLSALSFDLSVWD
CCCEEEEEEECCCCCCCCCEEEECHHHHCCHHHHHCEEECCCCHHHHHHHHHHHHHHHHH
IFGGLGAGATVVLPEEDRLRDPSYWLDLCDRHEITVWNSAPPLLEMLVDYAEIDPEAAAH
HHHCCCCCCEEEECCHHHCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHH
ALRNLRMVMLSGDWIPVTLPRRLKELAPNATVMSLGGATEASIWSICHRTSDADEHGPSI
HHHHCEEEEEECCEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCHHCCCCC
PYGRALRGQWFRILDTEGVPVPLGTPGILHIGGHGVARGYLGDPERTAERFCEHPRLGER
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHHHCCCCHHHH
LYNTGDEGMWLPNGEIRFLGRVDRQVKINGFRIELGEVDAALARCASVKSAISAAPQDAS
HHCCCCCCEECCCCCEEEEEECCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
GRKRLLGHVVPTQPERFDDSVLRRELAEHLPSYMIPSRFVVHDHLPVTDNGKVDHKALPN
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
PWCAETAPEPQVEPEPEVLPEPDRGSATPAELGINSLDIVRLANRIEDATGTRPSLATLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
NQPWQESLAMVEVLEPRPALASEQKPELVPDRDREVIDVVGAGMALGARIRAEVPISEEP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCEEEEECCCCCCC
VEDQFVQVGQWLKQLRAVVEPAGCMQVTPPSGNILCAIDITPGEKADVSDHAPLTPLQLG
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
YLVGRADTWLGEPVAPHYYTEVEVADLDVVALQRALDEVVRAHPALMLGVHDDGNQGLSE
HHHCCCHHCCCCCCCCCEECEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
ALRPRLVVTDLRDHPDPDGELERIRAVGCAGVSDPLGTAWFQLRATLLPTAVRLHLSIDM
HHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHHH
LFCDVVGAGVLVSDLQRAYNGETLEPEQRGFLEFAQRVAQNFGAQVTAGASDAQPLPSVI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
GPWQQPTSARFERIRTEITSDVADELSRAAATMGVTLDALMATIISTTAGAITGSPAQPI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VATVLARPRGFERTVGEFTSTVRVVPDQGDFVARAKSATHTLVTATDRALRCESEPRQGS
HHHHHHCCCCCHHHHHHHHCEEEEECCCCCHHHHHCCCCEEEEEECCHHHCCCCCCCCCC
AEVTPIVYSSGLHAVGDQSEVLGTWGKTIVAQSWTPQVLVDVQLFRTESGLALIVDYAVD
CCCCEEEEECCCCCCCCCHHHHHHCCCHHEECCCCCCEEEEEEEEECCCCCEEEEEHHHH
ALQPGAGRAFADGIVAAMRQCAMGAGMDSIWPQLRVPGLRAVDTRWTAFDGDSAPSSTKP
HCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCHHHCCCCCEEECCEEEEECCCCCCCCCCC
DHLIEVDIVAHELGSVLGITLEAQSYDKGFFDVGASSVDLIAMRNALVSRGYSLTLLDVF
CCEEEEHHHHHHHHHHHEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEEHHH
AHPSVLQLGRFIAPDTPTTSQVTTDSAHQRGHRRRRIARALNGELS
CCCCHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNTTTTTDTITEILTAIYGPVDPQQSLSHLGIDSMTAVRLQREIHHATGIYLPLITFLGD
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATVATLVRAVDNAEPAALETSTRTIPTNGRTMTPVQATYWVGRQPDYALGGIATRFYMEH
HHHHHHHHHHCCCCCCEEECCCCEECCCCCEECCCEEEEECCCCCCCHHHHHHEEEEEEE
DITIDGPMDEWIDALRRSWNTVVQRHGMLRATVDRDGKISIADTVTEHPLPVHNADHAAE
CCEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCHHHH
VRERLAHRTADLGTWPVHDIELTTITATTVRIHCGFDVILIDYPSIMRVLNDWGRALAGY
HHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEEEECEEEEEECCHHHHHHHHHHHHHHHCC
DLGTEDTSFSDLIAQGIAEPCPSDEAYWRERAPRLLPGPLDLAEMTYDAATTPEFHRHTR
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHH
TIAAQQWKQFVDNAHAHGTNASSALLAVAAHSLRHVGPRRSFTLGATFFSPDVLEHGPVG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHCCCCCC
DFTRTGVVELPDTADTFAQQASAAQHELWEAFDHASVTSADIMRWRNSDTTGQALPDYPV
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCC
VFTSALGHGDSTDWPGVMTWGVSQTPQVLMDLLHWESDGDLVLAWDCVDAALPENFADNA
HHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHCCCCCCCCH
IDIAYAVIQQLTNPAVWTDPTVVADPWLRMPGPMERIGESELIDAPLRAQYEAAPEARAV
HHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHCCCHHHCCCCHHHHHCCCCCCEEE
IAGEQSWTRAELDHHSERLAAAVARAAHDHDVVRADAPVLVMMQKSCMQVAAVCAVVRAG
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHCC
FAYIPVDPSWPMERVQSVMQRSGAVVCLADEGVAIPEGLHRIPLSEQGAEATGYTGRQSQ
CEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
PEDLAYVIFTSGSTGQPKGVAIEHRAARTTIDDINQRFEITDTDVVLGLSALSFDLSVWD
CCCEEEEEEECCCCCCCCCEEEECHHHHCCHHHHHCEEECCCCHHHHHHHHHHHHHHHHH
IFGGLGAGATVVLPEEDRLRDPSYWLDLCDRHEITVWNSAPPLLEMLVDYAEIDPEAAAH
HHHCCCCCCEEEECCHHHCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHH
ALRNLRMVMLSGDWIPVTLPRRLKELAPNATVMSLGGATEASIWSICHRTSDADEHGPSI
HHHHCEEEEEECCEEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCHHCCCCC
PYGRALRGQWFRILDTEGVPVPLGTPGILHIGGHGVARGYLGDPERTAERFCEHPRLGER
CCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCEECCCCCCHHHHHHHHHCCCCHHHH
LYNTGDEGMWLPNGEIRFLGRVDRQVKINGFRIELGEVDAALARCASVKSAISAAPQDAS
HHCCCCCCEECCCCCEEEEEECCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
GRKRLLGHVVPTQPERFDDSVLRRELAEHLPSYMIPSRFVVHDHLPVTDNGKVDHKALPN
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
PWCAETAPEPQVEPEPEVLPEPDRGSATPAELGINSLDIVRLANRIEDATGTRPSLATLL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
NQPWQESLAMVEVLEPRPALASEQKPELVPDRDREVIDVVGAGMALGARIRAEVPISEEP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCEEEEECCCCCCC
VEDQFVQVGQWLKQLRAVVEPAGCMQVTPPSGNILCAIDITPGEKADVSDHAPLTPLQLG
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
YLVGRADTWLGEPVAPHYYTEVEVADLDVVALQRALDEVVRAHPALMLGVHDDGNQGLSE
HHHCCCHHCCCCCCCCCEECEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHH
ALRPRLVVTDLRDHPDPDGELERIRAVGCAGVSDPLGTAWFQLRATLLPTAVRLHLSIDM
HHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEHHHH
LFCDVVGAGVLVSDLQRAYNGETLEPEQRGFLEFAQRVAQNFGAQVTAGASDAQPLPSVI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
GPWQQPTSARFERIRTEITSDVADELSRAAATMGVTLDALMATIISTTAGAITGSPAQPI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VATVLARPRGFERTVGEFTSTVRVVPDQGDFVARAKSATHTLVTATDRALRCESEPRQGS
HHHHHHCCCCCHHHHHHHHCEEEEECCCCCHHHHHCCCCEEEEEECCHHHCCCCCCCCCC
AEVTPIVYSSGLHAVGDQSEVLGTWGKTIVAQSWTPQVLVDVQLFRTESGLALIVDYAVD
CCCCEEEEECCCCCCCCCHHHHHHCCCHHEECCCCCCEEEEEEEEECCCCCEEEEEHHHH
ALQPGAGRAFADGIVAAMRQCAMGAGMDSIWPQLRVPGLRAVDTRWTAFDGDSAPSSTKP
HCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCHHHCCCCCEEECCEEEEECCCCCCCCCCC
DHLIEVDIVAHELGSVLGITLEAQSYDKGFFDVGASSVDLIAMRNALVSRGYSLTLLDVF
CCEEEEHHHHHHHHHHHEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEEHHH
AHPSVLQLGRFIAPDTPTTSQVTTDSAHQRGHRRRRIARALNGELS
CCCCHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366034 [H]