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The map label for this gene is dcd

Identifier: 38234691

GI number: 38234691

Start: 2208692

End: 2209255

Strand: Reverse

Name: dcd

Synonym: DIP2142

Alternate gene names: 38234691

Gene position: 2209255-2208692 (Counterclockwise)

Preceding gene: 38234692

Following gene: 38234690

Centisome position: 88.77

GC content: 52.13

Gene sequence:

>564_bases
GTGTTGTATTCCGACAAAGACATTCGTGTCGCTATTGATGCTGGCGAGTTAGGCATTGAGCCTTTCGACGCCGACCTGAT
TCAGCCGTCGTCGATTGATGTTCGTATGGATCGACTCTTCCGTGTATTTAATAACTCTAAGTACACGCATATCGATCCGA
AGCAGCAGCAGGATGAGCTAACGAGTTTGGTTGAGGTTCCAGAAGGGGAGCCGTTTGTTCTTCACCCAGGTGAGTTTGTG
CTGGGTTCTACGTTGGAGAAGTTCACTCTTCCTGCGCATATTGCTGGCCGTTTGGAAGGTAAGTCGTCGTTGGGCCGGTT
GGGTTTGCTCACGCACTCCACTGCGGGCTTTATTGATCCAGGTTTTTCCGGCTACATCACGTTGGAGCTTTCTAACGTTG
CTAATCTGCCGATCACGCTGTGGCCAGGGATGAAGGTGGGCCAATTGGCGTTGTTTAAGATGACGTCGCCGGCGCAGGCT
CCTTATGGTTCAAATGTGCTGGGCTCGAAGTATCAGGGTCAGCGCGGACCTACTCCGTCGAAGGCGTATCTCAACTTCCG
GTAG

Upstream 100 bases:

>100_bases
CAGCTTGGGAAGCTGATGTTCTACCATTGAACTACATCGGCAGTGCTATTTTTCAGTAGCGTCATTATGATAGCACTTCC
CATCGCGTACACTAAACGGC

Downstream 100 bases:

>100_bases
TCCTCATGCGGATTGGGGTTTTCGGTGCGGGTTACCTAGGTATTACGCATGCTGCGTGTATGTCGCACCTTGGCCACGAG
GTGGTGGCTGTTGATACTGA

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MLYSDKDIRVAIDAGELGIEPFDADLIQPSSIDVRMDRLFRVFNNSKYTHIDPKQQQDELTSLVEVPEGEPFVLHPGEFV
LGSTLEKFTLPAHIAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGYITLELSNVANLPITLWPGMKVGQLALFKMTSPAQA
PYGSNVLGSKYQGQRGPTPSKAYLNFR

Sequences:

>Translated_187_residues
MLYSDKDIRVAIDAGELGIEPFDADLIQPSSIDVRMDRLFRVFNNSKYTHIDPKQQQDELTSLVEVPEGEPFVLHPGEFV
LGSTLEKFTLPAHIAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGYITLELSNVANLPITLWPGMKVGQLALFKMTSPAQA
PYGSNVLGSKYQGQRGPTPSKAYLNFR
>Mature_187_residues
MLYSDKDIRVAIDAGELGIEPFDADLIQPSSIDVRMDRLFRVFNNSKYTHIDPKQQQDELTSLVEVPEGEPFVLHPGEFV
LGSTLEKFTLPAHIAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGYITLELSNVANLPITLWPGMKVGQLALFKMTSPAQA
PYGSNVLGSKYQGQRGPTPSKAYLNFR

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=190, Percent_Identity=40.5263157894737, Blast_Score=136, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_CORDI (Q6NEW7)

Other databases:

- EMBL:   BX248360
- RefSeq:   NP_940458.1
- HSSP:   P28248
- ProteinModelPortal:   Q6NEW7
- SMR:   Q6NEW7
- GeneID:   2649612
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP2142
- NMPDR:   fig|257309.1.peg.2049
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   Q6NEW7
- ProtClustDB:   PRK00416
- BioCyc:   CDIP257309:DIP2142-MONOMER
- BRENDA:   3.5.4.13
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20495; Mature: 20495

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYSDKDIRVAIDAGELGIEPFDADLIQPSSIDVRMDRLFRVFNNSKYTHIDPKQQQDEL
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHH
TSLVEVPEGEPFVLHPGEFVLGSTLEKFTLPAHIAGRLEGKSSLGRLGLLTHSTAGFIDP
HHHHCCCCCCEEEECCCCEEECCCHHHHCCCHHHEEEECCCCCCCEEEEEEECCCCCCCC
GFSGYITLELSNVANLPITLWPGMKVGQLALFKMTSPAQAPYGSNVLGSKYQGQRGPTPS
CCCEEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
KAYLNFR
CEEEECC
>Mature Secondary Structure
MLYSDKDIRVAIDAGELGIEPFDADLIQPSSIDVRMDRLFRVFNNSKYTHIDPKQQQDEL
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHH
TSLVEVPEGEPFVLHPGEFVLGSTLEKFTLPAHIAGRLEGKSSLGRLGLLTHSTAGFIDP
HHHHCCCCCCEEEECCCCEEECCCHHHHCCCHHHEEEECCCCCCCEEEEEEECCCCCCCC
GFSGYITLELSNVANLPITLWPGMKVGQLALFKMTSPAQAPYGSNVLGSKYQGQRGPTPS
CCCEEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
KAYLNFR
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910