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The map label for this gene is aspC [H]

Identifier: 38234685

GI number: 38234685

Start: 2200331

End: 2201602

Strand: Direct

Name: aspC [H]

Synonym: DIP2136

Alternate gene names: 38234685

Gene position: 2200331-2201602 (Clockwise)

Preceding gene: 38234683

Following gene: 38234686

Centisome position: 88.42

GC content: 53.62

Gene sequence:

>1272_bases
ATGAATAACAAAAAAGAGACTCCACAAGCAGCCCCTGCCCAACGCAAGCGCACACGGCGGATATTTGATCAGTCGGACAA
GTTGAAAAATGTGCTGTATGAAATCCGTGGGCCGGTGACGGCTGAAGCAGAGGCCATGGAGCTCGACGGGCACCGGATTC
TCAAGCTCAACACGGGCAACCCTGCGATCTTTGGGTTCGAGGCCCCTGATGTGATCATGCGTGACATGATTGCGTCCTTG
CCTACGTCGCAAGGCTATTCCACGTCGAAAGGCATCATTCCGGCACGTCGTGCGATCGTAACACGCTACGAGGTCATTCC
AGGTTTTCCTGCTTTTGACGTAGATGATGTTTACATCGGCAATGGTGTATCCGAGCTGATTACCATGACCACCCAAGCGT
TGCTGAACAACGGCGACGAAGTGCTCATTCCGATGCCGGATTATCCGCTGTGGACTGCGGCGACGTCTCTTGCGGGCGGC
AAACCGGTGCACTATCTGTGCGATGAGGAAGACGATTGGAACCCGTCGATCGAAGACATCAAGTCCAAGATCACCGAGCG
CACCAAAGCCATTGTGGTGATTAACCCTAATAACCCCACCGGTGCGGTGTATTCCAAGGAAGTCTTGCAAAAGATCGTTG
ATGTTGCCCGTGAACATGATCTGCTGATTTTGGCCGATGAGATCTACGATCGCATTCTTTACGATGGCGCCGTGCACACC
AACATCGCAGCTCTTGCACCTGATCTTTTGTGCATCACTTTCAATGGTTTGTCTAAGGCTTATCGTGTGGCGGGTTATCG
TGCCGGCTGGATGATCGTCACCGGCCCGAAGAATAATGCTCGCGGTTTTATCGAGGGTCTCGATTTGCTGTCGGGCACCC
GTCTTTGCGCTAATGTGCCAGGCCAGCACGCAATCCAGGTGGCGTTGGGTGGCCGCCAGTCGATTTACGATCTCACAGGT
CAAGGTGGCCGTTTGCTGGAGCAGCGCAATGTGACGTGGGAGAAGCTCAACGCTATTCCTGGCGTGAGCTGCGTGAAGCC
GATGGGTGCGTTGTATGCCTTCCCGAAGCTCGACTTGGAGTACTACGACATCAAGGATGATGCCCAGCTGATGCTTGATT
TGCTGCGCCAGGAAAAAATCTTGATGGTACAGGGTACGGGCTTTAACTGGGATAAGCCGGATCATTTCCGTGTGGTTACG
TTGCCGTGGGCTTCACAGTTGTCGGAGGCCATGGACCGGTTGGGTAACTTCCTAGCCAGCTATAAGCAGTAA

Upstream 100 bases:

>100_bases
CTGCGGGAAACAGCGTTCAGTGCTAGATACTCAAAATTAGTCGTGACTGATGGTGGGGTAATTAATGCCGGTGGGGTAAA
AAAGTGGCAACATTGGGGCG

Downstream 100 bases:

>100_bases
TTACAGGGAAAGGGTTTTCTACGTGGGTCGCCATAGTTCAGCTCCGCAGTCCCGGTCGCAGCGTCTGCCACGTGCACCGC
GCGTATCGACGCCTCCTCGC

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MNNKKETPQAAPAQRKRTRRIFDQSDKLKNVLYEIRGPVTAEAEAMELDGHRILKLNTGNPAIFGFEAPDVIMRDMIASL
PTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVDDVYIGNGVSELITMTTQALLNNGDEVLIPMPDYPLWTAATSLAGG
KPVHYLCDEEDDWNPSIEDIKSKITERTKAIVVINPNNPTGAVYSKEVLQKIVDVAREHDLLILADEIYDRILYDGAVHT
NIAALAPDLLCITFNGLSKAYRVAGYRAGWMIVTGPKNNARGFIEGLDLLSGTRLCANVPGQHAIQVALGGRQSIYDLTG
QGGRLLEQRNVTWEKLNAIPGVSCVKPMGALYAFPKLDLEYYDIKDDAQLMLDLLRQEKILMVQGTGFNWDKPDHFRVVT
LPWASQLSEAMDRLGNFLASYKQ

Sequences:

>Translated_423_residues
MNNKKETPQAAPAQRKRTRRIFDQSDKLKNVLYEIRGPVTAEAEAMELDGHRILKLNTGNPAIFGFEAPDVIMRDMIASL
PTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVDDVYIGNGVSELITMTTQALLNNGDEVLIPMPDYPLWTAATSLAGG
KPVHYLCDEEDDWNPSIEDIKSKITERTKAIVVINPNNPTGAVYSKEVLQKIVDVAREHDLLILADEIYDRILYDGAVHT
NIAALAPDLLCITFNGLSKAYRVAGYRAGWMIVTGPKNNARGFIEGLDLLSGTRLCANVPGQHAIQVALGGRQSIYDLTG
QGGRLLEQRNVTWEKLNAIPGVSCVKPMGALYAFPKLDLEYYDIKDDAQLMLDLLRQEKILMVQGTGFNWDKPDHFRVVT
LPWASQLSEAMDRLGNFLASYKQ
>Mature_423_residues
MNNKKETPQAAPAQRKRTRRIFDQSDKLKNVLYEIRGPVTAEAEAMELDGHRILKLNTGNPAIFGFEAPDVIMRDMIASL
PTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVDDVYIGNGVSELITMTTQALLNNGDEVLIPMPDYPLWTAATSLAGG
KPVHYLCDEEDDWNPSIEDIKSKITERTKAIVVINPNNPTGAVYSKEVLQKIVDVAREHDLLILADEIYDRILYDGAVHT
NIAALAPDLLCITFNGLSKAYRVAGYRAGWMIVTGPKNNARGFIEGLDLLSGTRLCANVPGQHAIQVALGGRQSIYDLTG
QGGRLLEQRNVTWEKLNAIPGVSCVKPMGALYAFPKLDLEYYDIKDDAQLMLDLLRQEKILMVQGTGFNWDKPDHFRVVT
LPWASQLSEAMDRLGNFLASYKQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=486, Percent_Identity=26.7489711934156, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI215599424, Length=375, Percent_Identity=28.8, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=28.5340314136126, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4885351, Length=445, Percent_Identity=25.8426966292135, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI95147551, Length=243, Percent_Identity=27.1604938271605, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=243, Percent_Identity=27.1604938271605, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56713254, Length=160, Percent_Identity=34.375, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI56713256, Length=160, Percent_Identity=34.375, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881281, Length=150, Percent_Identity=31.3333333333333, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=61.5960099750624, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1788722, Length=405, Percent_Identity=27.4074074074074, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786816, Length=238, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=420, Percent_Identity=30.2380952380952, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71981209, Length=475, Percent_Identity=24.4210526315789, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=213, Percent_Identity=30.9859154929577, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=213, Percent_Identity=30.9859154929577, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=219, Percent_Identity=30.5936073059361, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=23.8095238095238, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=356, Percent_Identity=28.0898876404494, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=379, Percent_Identity=26.9129287598945, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=25.3164556962025, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=27.3458445040214, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI45551451, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641770, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641760, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641768, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641766, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24641764, Length=396, Percent_Identity=28.030303030303, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI28573069, Length=200, Percent_Identity=26.5, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646114, Length=200, Percent_Identity=26.5, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573067, Length=200, Percent_Identity=26.5, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573065, Length=200, Percent_Identity=26.5, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 46909; Mature: 46909

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKKETPQAAPAQRKRTRRIFDQSDKLKNVLYEIRGPVTAEAEAMELDGHRILKLNTGN
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCC
PAIFGFEAPDVIMRDMIASLPTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVDDVYIG
CEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
NGVSELITMTTQALLNNGDEVLIPMPDYPLWTAATSLAGGKPVHYLCDEEDDWNPSIEDI
CCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCHHHH
KSKITERTKAIVVINPNNPTGAVYSKEVLQKIVDVAREHDLLILADEIYDRILYDGAVHT
HHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHC
NIAALAPDLLCITFNGLSKAYRVAGYRAGWMIVTGPKNNARGFIEGLDLLSGTRLCANVP
CHHHHCCCEEEEEECCHHHHHHHHCEECCEEEEECCCCCCCHHHHHHHHHCCCHHHHCCC
GQHAIQVALGGRQSIYDLTGQGGRLLEQRNVTWEKLNAIPGVSCVKPMGALYAFPKLDLE
CCCEEEEEECCCCCEEECCCCCCCCHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCE
YYDIKDDAQLMLDLLRQEKILMVQGTGFNWDKPDHFRVVTLPWASQLSEAMDRLGNFLAS
EEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
YKQ
HCC
>Mature Secondary Structure
MNNKKETPQAAPAQRKRTRRIFDQSDKLKNVLYEIRGPVTAEAEAMELDGHRILKLNTGN
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCC
PAIFGFEAPDVIMRDMIASLPTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVDDVYIG
CEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
NGVSELITMTTQALLNNGDEVLIPMPDYPLWTAATSLAGGKPVHYLCDEEDDWNPSIEDI
CCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCHHHH
KSKITERTKAIVVINPNNPTGAVYSKEVLQKIVDVAREHDLLILADEIYDRILYDGAVHT
HHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHC
NIAALAPDLLCITFNGLSKAYRVAGYRAGWMIVTGPKNNARGFIEGLDLLSGTRLCANVP
CHHHHCCCEEEEEECCHHHHHHHHCEECCEEEEECCCCCCCHHHHHHHHHCCCHHHHCCC
GQHAIQVALGGRQSIYDLTGQGGRLLEQRNVTWEKLNAIPGVSCVKPMGALYAFPKLDLE
CCCEEEEEECCCCCEEECCCCCCCCHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCE
YYDIKDDAQLMLDLLRQEKILMVQGTGFNWDKPDHFRVVTLPWASQLSEAMDRLGNFLAS
EEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
YKQ
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]