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The map label for this gene is insK [H]

Identifier: 38234672

GI number: 38234672

Start: 2175813

End: 2176625

Strand: Reverse

Name: insK [H]

Synonym: DIP2123

Alternate gene names: 38234672

Gene position: 2176625-2175813 (Counterclockwise)

Preceding gene: 38234673

Following gene: 38234669

Centisome position: 87.46

GC content: 51.91

Gene sequence:

>813_bases
TTGCTTGCCGTCTCTGGCCTGGCTAGGTCAACGTTTTTTGATCACCAGCGCCGCCTTGACAAGCCAGATAAGTACGCCGA
CCTCAAGGAACAGATTACGACGATCTTTCACGACTCCAACGCCACGTTTGGCTATCGCCGTATCTGGCGTGCGCTGCGCA
ACAACAACACGATCGTCAACAAGAAGGTGGTTCAAAGGCTCATGCGCGAGCAAGGATTGGTATCGAAGATCAGGCGTAAG
AAGTACAACTCCTACCGTGGCACTGTCAGCCACATTGCTGACAACGTGCTTGGCCGACGCTTCATCCAAGACGCACCGAA
CAAAGTGTGGGTTAGTGACGTCACAGAGTTCCGGGTAGCCGGCACCAAAGTGTACTTGTCGCCGATTATGGATCTGTTTG
ACCGAACCATCTTGGCGCATACTCTGTCTACGTCACCGAATACTCAGCTCACATCACGCTCGTTGGCGGACGCCATTGCC
ATGTTTAGCCCGGGTAAAGGACTGATTGTGCACACTGACCAAGGCTTCCAGTACCAGCACGCAAGCTGGCGCAACCTAAT
TGAAAGCGTTGGCGGTGTGCAATCGATGTCGCGCAAAGGCAATTGCTACGACAACGCGGTGATGGAAAATTTCTTCGGAC
ACTTGAAATCAGAGATGTACCACGATGTTTACTTCACCAGTGTCGATGAGCTTTGCCAAGCTATCGATGAGTACATACTG
TGGTACAACACGTACCGACTCCAAGAACGATTCAAGGGTCTGGCTCCGATGCAATATCGGAACCAGACCCTTGCAAAGAC
CCTAACCGTTTAG

Upstream 100 bases:

>100_bases
AAGTGGCGTACCTAAAAAAATTGAGGGACTTGAGGGATCAACGACGAGGCTGAAAGTTGCGGCCATCATCACCCTCAAGT
CCGATCACCGCCTGGATGAC

Downstream 100 bases:

>100_bases
AATTAACCCAGTCCGGAAAACGGGGAGCAGTTCACCCCTCGAAAACTCGCGGTTTCTCGAGAGGGTTGGTGTGGATTTTT
TGTTGGTGGGGGACTAAGCG

Product: putative transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLAVSGLARSTFFDHQRRLDKPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPIMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRNLIESVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYHDVYFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV

Sequences:

>Translated_270_residues
MLAVSGLARSTFFDHQRRLDKPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPIMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRNLIESVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYHDVYFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV
>Mature_270_residues
MLAVSGLARSTFFDHQRRLDKPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPIMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRNLIESVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYHDVYFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=225, Percent_Identity=30.2222222222222, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1789981, Length=263, Percent_Identity=44.8669201520913, Blast_Score=247, Evalue=5e-67,
Organism=Escherichia coli, GI1788405, Length=271, Percent_Identity=30.9963099630996, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787263, Length=271, Percent_Identity=30.9963099630996, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786753, Length=271, Percent_Identity=30.9963099630996, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786570, Length=271, Percent_Identity=30.9963099630996, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786490, Length=271, Percent_Identity=30.9963099630996, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31254; Mature: 31254

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]