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The map label for this gene is fre [C]

Identifier: 38234659

GI number: 38234659

Start: 2160416

End: 2161519

Strand: Direct

Name: fre [C]

Synonym: DIP2110

Alternate gene names: 38234659

Gene position: 2160416-2161519 (Clockwise)

Preceding gene: 38234656

Following gene: 38234662

Centisome position: 86.81

GC content: 59.6

Gene sequence:

>1104_bases
TTGGTAACCGTGACCGCTCAATCAATCCAGGCCGTTGCCGACAAACTTCGCGCCCACCGCGCGGAGTTCACTCAGGCAGC
CAATCAAAAGCCGGACTCCCCTCTCGCGGACGCCATCGCGCAGCTCGTCGATCATACCGATCTAGACGGACACGTTCCGG
AATCGATCGCTACTTCATGGCTACAGCACGCAGCCGCCGCCGAAAGCCTCGGGGTATCACGTGACTACTACCTCACGCTT
GCCGACGCCTCCCGCAGCGCCCTGCGCCACATTTGCGCAGACCTCCCCTTCGCCGAGGTCCTCGGTGCCGAACGCGCTAT
CACGTCGATAGCCAACACACTGAGCAGCGCGCCCCTGCCCAACGCAGCAGTACCCGCACAAGTCGTGCAAGTAGAAAAGC
GCAGCAGCGCTATCTCCGTGGTACGACTGCAAGCAGAAACAGCTATCAACTACACCACCACCCAGTACGTCACCGTCACC
GCCGACTATTTACGTGGAGCGCGTCGTGAGCTCTTTCCCACCATCCCACCCAACGAGTACGGCCAAATCGAATTCCATAT
CCGCCATGAAGGTATGATCTCTACATTGCTCGCCGGCGCACATGTAGGCGACACGTGGTGGATCAGCACAGGCCAAGGCG
GTTTTGATTACGTAGAAAACCAAGACATGGTGTTTATCGCCCACGGGGTAGGACTTGCAGCACTACGCCCCATCATCGTC
GATTTCCTCCGCCTAGCCGAGCCCCCTCGAGTCCACCTCTTCCTCGCAGCCGACTACCCAGGCGAACTCTACGAGCTCGC
TGGCCTATGGAGCCTAGCGTCGACCGCACCTTGGCTGTCCGTCACCCCTGTTGTTGCCCATGAAGAAGACGCCTGGTGGG
TAGCCCCCACCCAGCATTCTCACCCACCGCGCGGGCTACACATCACCCAAGTCGGACAAGCCGGAGAAATAGTCGCAGGT
TATGGCACGTGGGAAGATCGTCGCATCTTGATCGCCGGTCCCTCCCACGACGTGGCAGCCTCCCGCAAGGCACTTATTCG
CCGCGGAACGCCACCCACCATCATCCACACGCAAACCTTCGATTACTCACCGTTTTGGTTATAA

Upstream 100 bases:

>100_bases
AGCAGCATTTTGGCTACGGGAACGTTGAGGGCGTACAACGCCGCGGCGAGGATAGCCAGCAGGCTCGCTTGAGTTTTCAT
AATGCGAAAATACACTACGA

Downstream 100 bases:

>100_bases
CCCGCATCTGCTAACACAGGGATAGCCTCGCGGGTACGCCTAACGAGGTCACGGTTGACGTTCACCATGAACAACTCCTC
CCCCGTACCGGCCTCGGCAA

Product: hypothetical protein

Products: NAD(P); FMNH2; 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: Oxidoreductase; Monooxygenase; 2-Polyprenylphenol Hydroxylase-Like Oxidoreductase; 2-Polyprenylphenol Hydroxylase-Like Protein; Globin

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVTVTAQSIQAVADKLRAHRAEFTQAANQKPDSPLADAIAQLVDHTDLDGHVPESIATSWLQHAAAAESLGVSRDYYLTL
ADASRSALRHICADLPFAEVLGAERAITSIANTLSSAPLPNAAVPAQVVQVEKRSSAISVVRLQAETAINYTTTQYVTVT
ADYLRGARRELFPTIPPNEYGQIEFHIRHEGMISTLLAGAHVGDTWWISTGQGGFDYVENQDMVFIAHGVGLAALRPIIV
DFLRLAEPPRVHLFLAADYPGELYELAGLWSLASTAPWLSVTPVVAHEEDAWWVAPTQHSHPPRGLHITQVGQAGEIVAG
YGTWEDRRILIAGPSHDVAASRKALIRRGTPPTIIHTQTFDYSPFWL

Sequences:

>Translated_367_residues
MVTVTAQSIQAVADKLRAHRAEFTQAANQKPDSPLADAIAQLVDHTDLDGHVPESIATSWLQHAAAAESLGVSRDYYLTL
ADASRSALRHICADLPFAEVLGAERAITSIANTLSSAPLPNAAVPAQVVQVEKRSSAISVVRLQAETAINYTTTQYVTVT
ADYLRGARRELFPTIPPNEYGQIEFHIRHEGMISTLLAGAHVGDTWWISTGQGGFDYVENQDMVFIAHGVGLAALRPIIV
DFLRLAEPPRVHLFLAADYPGELYELAGLWSLASTAPWLSVTPVVAHEEDAWWVAPTQHSHPPRGLHITQVGQAGEIVAG
YGTWEDRRILIAGPSHDVAASRKALIRRGTPPTIIHTQTFDYSPFWL
>Mature_367_residues
MVTVTAQSIQAVADKLRAHRAEFTQAANQKPDSPLADAIAQLVDHTDLDGHVPESIATSWLQHAAAAESLGVSRDYYLTL
ADASRSALRHICADLPFAEVLGAERAITSIANTLSSAPLPNAAVPAQVVQVEKRSSAISVVRLQAETAINYTTTQYVTVT
ADYLRGARRELFPTIPPNEYGQIEFHIRHEGMISTLLAGAHVGDTWWISTGQGGFDYVENQDMVFIAHGVGLAALRPIIV
DFLRLAEPPRVHLFLAADYPGELYELAGLWSLASTAPWLSVTPVVAHEEDAWWVAPTQHSHPPRGLHITQVGQAGEIVAG
YGTWEDRRILIAGPSHDVAASRKALIRRGTPPTIIHTQTFDYSPFWL

Specific function: Catalyzes The Reduction Of Soluble Flavins By Reduced Pyridine Nucleotides. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.29 [C]

Molecular weight: Translated: 39977; Mature: 39977

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVTAQSIQAVADKLRAHRAEFTQAANQKPDSPLADAIAQLVDHTDLDGHVPESIATSW
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
LQHAAAAESLGVSRDYYLTLADASRSALRHICADLPFAEVLGAERAITSIANTLSSAPLP
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
NAAVPAQVVQVEKRSSAISVVRLQAETAINYTTTQYVTVTADYLRGARRELFPTIPPNEY
CCCCCHHHHHHHHHCCEEEEEEEEEHHEEEEEEEEEEEEEHHHHHCHHHHHCCCCCCCCC
GQIEFHIRHEGMISTLLAGAHVGDTWWISTGQGGFDYVENQDMVFIAHGVGLAALRPIIV
CEEEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
DFLRLAEPPRVHLFLAADYPGELYELAGLWSLASTAPWLSVTPVVAHEEDAWWVAPTQHS
HHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEECEEEEECCCCEEECCCCCC
HPPRGLHITQVGQAGEIVAGYGTWEDRRILIAGPSHDVAASRKALIRRGTPPTIIHTQTF
CCCCCEEEEECCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECC
DYSPFWL
CCCCCCC
>Mature Secondary Structure
MVTVTAQSIQAVADKLRAHRAEFTQAANQKPDSPLADAIAQLVDHTDLDGHVPESIATSW
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
LQHAAAAESLGVSRDYYLTLADASRSALRHICADLPFAEVLGAERAITSIANTLSSAPLP
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
NAAVPAQVVQVEKRSSAISVVRLQAETAINYTTTQYVTVTADYLRGARRELFPTIPPNEY
CCCCCHHHHHHHHHCCEEEEEEEEEHHEEEEEEEEEEEEEHHHHHCHHHHHCCCCCCCCC
GQIEFHIRHEGMISTLLAGAHVGDTWWISTGQGGFDYVENQDMVFIAHGVGLAALRPIIV
CEEEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
DFLRLAEPPRVHLFLAADYPGELYELAGLWSLASTAPWLSVTPVVAHEEDAWWVAPTQHS
HHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEECEEEEECCCCEEECCCCCC
HPPRGLHITQVGQAGEIVAGYGTWEDRRILIAGPSHDVAASRKALIRRGTPPTIIHTQTF
CCCCCEEEEECCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECC
DYSPFWL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD(P)H2; FMN [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; FMN; 2 2-octaprenylphenol; O2 [C]

Specific reaction: NAD(P)H2 + FMN = NAD(P) + FMNH2 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA