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The map label for this gene is rtcB [H]

Identifier: 38234589

GI number: 38234589

Start: 2077594

End: 2078898

Strand: Reverse

Name: rtcB [H]

Synonym: DIP2025

Alternate gene names: 38234589

Gene position: 2078898-2077594 (Counterclockwise)

Preceding gene: 38234590

Following gene: 38234588

Centisome position: 83.54

GC content: 63.83

Gene sequence:

>1305_bases
TTGACCATTTCCCGGGAAAGCGGCCCTGCTTATCCCGGACGTTGGTGCGAGCCGCGCGACCCGCGCGCACAACTCACAAG
TCAGCCGCCCAAGCAGGCCCTTTCTCACGAACTGCGTTACGTAAACGCAGAGAAAGGCTCTCTTATGCGCCTGCACAACT
TCGCCTCCATTGTTGAAGACAAGACGGTGGCGCAGGCACAACTCGTCGCTGACCTGCCCTTCGTCTACCCACACGTGGCG
CTCATGCCTGATGCCCACTTTGGCAAAGGCTCTTCGGTCGGCACCGTCTTCGGCACGCTGCGCGCCGTCATCCCGGCGGC
TGTCGGCGTGGACATCGGCTGCGGCATGATCGCCGTGCGGACCCACCTCACGCACGCGGATATCCAGGACTTCGCTCTCG
AGGACCTGCGCACCGCGGTCGAAGATTCCATTCCGCTCTCGCCCGGAAACTACAACGGCTGGATCATGGACCCGCGTACC
GAGGCCCGCACGCGCGAGCTCGCGCAGTTGGCTCAGGACACCGGCGTGGATCTCGGTCACTCCAAAAATTGGCGTCAGCA
GCTGGGCAGCTTGGGCGGCGGCAACCACTTCATCGAGCTGTGTCTCGACGAAGATGACCGCGTCTGGCTGTTCCTGCATT
CTGGCTCGCGCGGCGTGGGTAACAAGATTGCACAGAAGCACATCAAGGCCGCGCAGCGCCACTGCGAGAAGCACTGGATC
CAGCTCGCGGACAAGGACCTGGCCTACCTCGTCGAGGGTACGCCCGAGTTCGACTCCTACATTGCGGATCTCCACTGGGC
ACAGCACTTTGCGCTGCTCAACCGCGATGAGATGATGGACCGATTCCTCGACTGCGTCGCCACCTGGTCCGGCGCGGATC
GCGAGACCCTCGAGCTCGAGCGCATCAACTGCCACCACAACTACACCCAGCGTGAGAACCACTACGGTAAGAACGTGTGG
CTCACACGCAAGGGCGCCATCAAGGCGGACGAAGGCGACCGCGGCCTCATCCCCGGCTCGATGGGCACCGCTAGCTACGT
CGTGGAGGGCAAGGGCTACGCGCCGGGCCTCAAGTCTGCGCCGCACGGCGCGGGTCGCGTCATGTCGCGTACCCAGGCCA
AGGCCCGCTTCACCGAGGCGGACCTTGCCGCACGCATGGAAGGCATCGTCTATCGTCCCGGCGCCGAGTTCGTCGATGAG
ATTCCGGACGCCTACAAGGACATCGACCGCGTGATGGCCGATGCCGCCCAGCTCGTCGAGGTCAAGCACACCCTGCGCCA
GATCCTCAACGTCAAGGGCACCTAA

Upstream 100 bases:

>100_bases
AAAGAAGAACAAGAAAGCATAAAGGAGGCGAATCGCGATGATGACCCATAACAATCAGCCGCTAGGACGCCTCTTTAAGC
AACTCTTCTAACAGGCTGAC

Downstream 100 bases:

>100_bases
CCTGCGCCATGATGGGACCGCCACTTTTAGTGGCGGTCCCTTGTGAGCTTTGCGACGCCCCTTCCTGCAGCGTCGCACCA
GCACGACGCTTTGCCTTATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTISRESGPAYPGRWCEPRDPRAQLTSQPPKQALSHELRYVNAEKGSLMRLHNFASIVEDKTVAQAQLVADLPFVYPHVA
LMPDAHFGKGSSVGTVFGTLRAVIPAAVGVDIGCGMIAVRTHLTHADIQDFALEDLRTAVEDSIPLSPGNYNGWIMDPRT
EARTRELAQLAQDTGVDLGHSKNWRQQLGSLGGGNHFIELCLDEDDRVWLFLHSGSRGVGNKIAQKHIKAAQRHCEKHWI
QLADKDLAYLVEGTPEFDSYIADLHWAQHFALLNRDEMMDRFLDCVATWSGADRETLELERINCHHNYTQRENHYGKNVW
LTRKGAIKADEGDRGLIPGSMGTASYVVEGKGYAPGLKSAPHGAGRVMSRTQAKARFTEADLAARMEGIVYRPGAEFVDE
IPDAYKDIDRVMADAAQLVEVKHTLRQILNVKGT

Sequences:

>Translated_434_residues
MTISRESGPAYPGRWCEPRDPRAQLTSQPPKQALSHELRYVNAEKGSLMRLHNFASIVEDKTVAQAQLVADLPFVYPHVA
LMPDAHFGKGSSVGTVFGTLRAVIPAAVGVDIGCGMIAVRTHLTHADIQDFALEDLRTAVEDSIPLSPGNYNGWIMDPRT
EARTRELAQLAQDTGVDLGHSKNWRQQLGSLGGGNHFIELCLDEDDRVWLFLHSGSRGVGNKIAQKHIKAAQRHCEKHWI
QLADKDLAYLVEGTPEFDSYIADLHWAQHFALLNRDEMMDRFLDCVATWSGADRETLELERINCHHNYTQRENHYGKNVW
LTRKGAIKADEGDRGLIPGSMGTASYVVEGKGYAPGLKSAPHGAGRVMSRTQAKARFTEADLAARMEGIVYRPGAEFVDE
IPDAYKDIDRVMADAAQLVEVKHTLRQILNVKGT
>Mature_433_residues
TISRESGPAYPGRWCEPRDPRAQLTSQPPKQALSHELRYVNAEKGSLMRLHNFASIVEDKTVAQAQLVADLPFVYPHVAL
MPDAHFGKGSSVGTVFGTLRAVIPAAVGVDIGCGMIAVRTHLTHADIQDFALEDLRTAVEDSIPLSPGNYNGWIMDPRTE
ARTRELAQLAQDTGVDLGHSKNWRQQLGSLGGGNHFIELCLDEDDRVWLFLHSGSRGVGNKIAQKHIKAAQRHCEKHWIQ
LADKDLAYLVEGTPEFDSYIADLHWAQHFALLNRDEMMDRFLDCVATWSGADRETLELERINCHHNYTQRENHYGKNVWL
TRKGAIKADEGDRGLIPGSMGTASYVVEGKGYAPGLKSAPHGAGRVMSRTQAKARFTEADLAARMEGIVYRPGAEFVDEI
PDAYKDIDRVMADAAQLVEVKHTLRQILNVKGT

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=435, Percent_Identity=27.1264367816092, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI2367224, Length=385, Percent_Identity=46.4935064935065, Blast_Score=332, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17506665, Length=441, Percent_Identity=26.984126984127, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585217, Length=441, Percent_Identity=26.530612244898, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 48165; Mature: 48034

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISRESGPAYPGRWCEPRDPRAQLTSQPPKQALSHELRYVNAEKGSLMRLHNFASIVED
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
KTVAQAQLVADLPFVYPHVALMPDAHFGKGSSVGTVFGTLRAVIPAAVGVDIGCGMIAVR
HHHHHHHHHHHCCHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
THLTHADIQDFALEDLRTAVEDSIPLSPGNYNGWIMDPRTEARTRELAQLAQDTGVDLGH
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCC
SKNWRQQLGSLGGGNHFIELCLDEDDRVWLFLHSGSRGVGNKIAQKHIKAAQRHCEKHWI
CCHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QLADKDLAYLVEGTPEFDSYIADLHWAQHFALLNRDEMMDRFLDCVATWSGADRETLELE
HHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEE
RINCHHNYTQRENHYGKNVWLTRKGAIKADEGDRGLIPGSMGTASYVVEGKGYAPGLKSA
EECCCCCCHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
PHGAGRVMSRTQAKARFTEADLAARMEGIVYRPGAEFVDEIPDAYKDIDRVMADAAQLVE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKHTLRQILNVKGT
HHHHHHHHHCCCCC
>Mature Secondary Structure 
TISRESGPAYPGRWCEPRDPRAQLTSQPPKQALSHELRYVNAEKGSLMRLHNFASIVED
CCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
KTVAQAQLVADLPFVYPHVALMPDAHFGKGSSVGTVFGTLRAVIPAAVGVDIGCGMIAVR
HHHHHHHHHHHCCHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
THLTHADIQDFALEDLRTAVEDSIPLSPGNYNGWIMDPRTEARTRELAQLAQDTGVDLGH
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCC
SKNWRQQLGSLGGGNHFIELCLDEDDRVWLFLHSGSRGVGNKIAQKHIKAAQRHCEKHWI
CCHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QLADKDLAYLVEGTPEFDSYIADLHWAQHFALLNRDEMMDRFLDCVATWSGADRETLELE
HHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEE
RINCHHNYTQRENHYGKNVWLTRKGAIKADEGDRGLIPGSMGTASYVVEGKGYAPGLKSA
EECCCCCCHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
PHGAGRVMSRTQAKARFTEADLAARMEGIVYRPGAEFVDEIPDAYKDIDRVMADAAQLVE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKHTLRQILNVKGT
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]