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The map label for this gene is lgrC [H]

Identifier: 38234573

GI number: 38234573

Start: 2055872

End: 2059675

Strand: Direct

Name: lgrC [H]

Synonym: DIP2009

Alternate gene names: 38234573

Gene position: 2055872-2059675 (Clockwise)

Preceding gene: 38234572

Following gene: 38234578

Centisome position: 82.61

GC content: 61.3

Gene sequence:

>3804_bases
ATGGTGGTTCCTGAGCAGTTTCTTCGTTCTGATAAGGCTCCTCGTCCGCGCACGTTGGTGGATATTTTTCGCTCATCGGT
GGCCGCCTTCCCAGAGGCTGCGGCCTTAGATTGCGGCGATGTGTTGACCTATGCGGATCTTGCAGAGTTGGTCGATGATC
GTGTTGCGCAGTTGCATGCTGCTGGGGTGGGTGCTGGTTGTCGGGTGGGTGTTCGGTTGCCCTCCGGGCAGCCGGATTTG
TATGTGACGATTTTGGCGGTGTTGTGTGCGGGGGCGGCTTATGTGCCAGTGGATGCAGATGATCCGGATGAGCGTGCGGA
GTTGGTGTTCGGGGAGGCCCACGTTGATGCGGTGTGGTCTGTTTCAGGGTTAAGGGTGACCACTGCGCAGGCGCAGCCGC
TGACCGCGGGGCCGCGTTTGGAGGATACGGCGTGGATTATTTTTACTTCCGGTTCGACGGGTAAGCCGAAGGGTGTTGCG
GTGTCGCATCGCAGCGCTGCTGCTTTTGTGGATGCTGAGCGTGAGTTGTTTGTGCGCGATCAGCCGATTGGCCCTGATGA
TCGCGTGTTGGCGGGGTTGTCGGTGGCGTTTGATGCCTCCTGTGAGGAGATGTGGCTAGCGTGGGGGCATGGGGCGTGTT
TGGTTCCAGCTCCGCGGTCGTTGGTGCGTACCGGGTTGGATTTGGGCCCGTGGTTGATTAGTCGTGATATTTCGATTGTG
TCGACGGTTCCCACTCTTGCGGGCATGTGGCCTGCGGAGGCGTTGGATAATGTGCGCTTGTTGATTTTGGGCGGTGAGGC
TTGTTCGGCGGAGTTGGTGGCCAGGGTGGCGTCGTCACGCCGCGAGGTGTGGAATACCTATGGTCCGACGGAGGCTACGG
TGGTCACGTGTGCTGCACGTTTGGAGGCTGGCCAACCGGTGGCGATTGGGTTGCCGCTGGCGGGGTGGGATACCGCGGTC
GTAGGTGCTGATGGTCAGCCGGTGGCTATGGGGGACGTTGGCGAGCTGGTTATTGGCGGGGTGGGTCTTGCTCGGTATCT
GGATCCGGTGAAGGATCGGGAGAAGTTTTCGGCGGAGCTTGGCTGGGAGCGGGCGTATCGTTCGGGGGATCATGTGCGCT
TGTGCGAGGACGGCTTGTATTTTGTGGGGCGTATCGACGACCAAGTCAAGATCGGTGGCCGCCGGATCGAGTTGGGCGAG
GTGGAGGCCCATGTGGCCGCGTTGCCCAATGTGGCGCAGTATGCGGTGGTGGTTCGTGAAACTGCCGCTGGTGAGAAGGT
GCTGGTGGCGTATGTGTCGCCGCAGGTTCCAGACGTTGATATTGATACTTCTGCTTTAGATGAGTTGCCTCGGGCGATGG
TGCCACGGCTTGTGGTGCTGCCGGAGATCCCGACGACTACGTCGGGTAAGGCGGATAAGAAGGCGTTGCCGTGGCCGTTG
GAGTCGGCGCAGGTCACGGGCTCGGATTTCACTCCAACGCAGCAGTGGTTGGCCCAGTTGTGGGTGGATGTGTTGGGGGT
TCCGGTTGGTGATGTGGATGCGGACTTTTTTGTTTTAGGTGGGACGTCGTTGGCGGCGGCTGGGGTGGTGTCGCGGATTC
GGCAGAAGGCTCCCACAATGTCGGTGCGGGATTTGTATGATCATCCGCGGTTGGGGGCGTTGGCTGAGGTGGTAGAGCAG
TTACCTGGTGCGGCGGTGACTAAGCGGCGTGAGTTGAGGCCGGTGCCGTGGGTTACGCGGGTGGCACAGGCGACCATTAT
TTGGTTGTGTGCAACCATTCGGGCGGCTAGTTGGGTGGCGTGGTTGTTGGTGCTCAACAATGTTGCTGCTGGTTGGGGTG
CTAGTTGGGCGCGCCCGCTGCCGTGGTTGTTCGTGGTGTTATTCACGGTGCTGGTGGCAACGCCTGTGGGGCGGTTGCCG
TTGGGGGCGTGGAGTGCGCGGCTTATCACAGCACGGATTTCGCCTGGGGATTATCCGCGCGGCGGTGTCACCCATGTGCG
CTTGTGGGCGGCACAGCGGCTTTTCGACGCCTTCGGTGCGGGTGATATTGCTGGCGCGACGTGGGTAAATTATTGCGCCC
GTGCATTGGGCGCCCAGGTTGGCCGTGGGGTGGATTTGCACACGATGCCACCGGTGACGGGCCTTTTGCGTTTGGGGGAT
CATTGCGCGGTGGAACCCGAGGTGGATCTTAGTGGCGTGTGGGTGGATGGCGATGTGGTCCATGTGGGTGCTATTGAGAT
TGCTGAGGATGCCCGCGTGGGTGCGCGTTCCACGTTGTTACCTGGCACGGTCATTGGTGCTGGTGCCCATATTGAGGCTG
GTTCGACGGTGACGGGTGCGGTGGTTAAAGCTGGTGCGCGGTGGTCGGGTTCGCCGGCGGCGAAGGTGGGGCGTTCCAAG
CATCGTTTCCCCAATGCACATCCGCCGCGTAGGTCGCGCTGGGTGCCGGTGTACGGGGTGTCGTCGTTAGTGTTGGCGCT
GCTGCCGTTGCTGGCGATAGCTGTCGGAATGGTGGTGGTGTGGCGTTGGCAGGAGCGTACCCATACTGCGTTGTGGTGGT
GGGTGCCGCTGGGTGTGGTGGCGGCCATGGGGTTGTATGCCCTGTTGGTGTTGGTGTTGGTTCGGTTGTTGGGTTGGCGG
CTTGCCCCTGGGATTACGGCGGTACGTTCGGCGCGAGGTTGGCGGGTGTGGTGCATTGAGCGCCTGCTTGACGACGCCCG
CACCTACCTGTTCCCGATGTATGCCTCGCTTATCACCCCGTGGTGGTTCCGCCTCCTAGGGGCGAAGGTAGGCAAGGATG
TGGAGATTTCTACGGCGGTGATGGTGCCCTCGTTATCCGAGATCCGCGATCGCGCTTTCTTGGCCGACGACACCCTCATC
GGTGGCTACGAGCTCGGCGGTGGCTGGATGCGCTTGGGGCGCACGATCATTGGCAAGCGCTCCTTCGTGGGTAACTCTGG
TATTGCGCTCCAAGGCCGCAAGCTAGCCAAAAATTCGCTGGTAGCGGTGCTCTCGCAGGTGCCTAAAAAAGCTCGTTCTG
GTTCTAACTGGTGGGGTTCGCCACCAGAACGGATGCGACGCGTCACCGTGAACAGTTGCGCCTCCGACACCAGTACCTTC
TACCCCACCGTGGGCAAAAAATTCCTACGCGCCATGGTAGAAATCCTTCGGCTAACAGCACCTATGACCAGTGGTTTCCT
CTTGGCCGCAGTGCTCGTTTCCGCGCAGTGGCTTCTAGGATTTGGGGTGGTGGCCGCACTATTTGGCACCGGCCTAGCCT
TGTGTGTCGCAGGCGCACTAGCCATCACGATCACCGCGGCGGTGAAATGGTGTACGGTGGGCCGTCACCGCCCAGGCAAC
CACCCTCTGTGGAGCTGGTTCGTGTGGCTCAACGAACTCCAAGACACCTTCGTCGAAGTCGTAGCAGCCCCCTGGTTCTT
CCATCACTGCACCGGCAGCGGCCTCATCAACTCAGGTCTTCGCCTCCTCGGCGTCCGCATCGGCCCCGGCGCGTGGATCG
ACAGCTACTGGTTCCCCGAAACCGACCTGTGCAACGTCGGTACAGCAGCCACCGTAGGCCCTGGAACAGTCGTACAAACC
CACCTGTTCCACGACCGCGTGATGAGCCTCGACCACGTCCACATAGGCGCAGGGGCAACCCTTGCCGCTCACTCCGTCAT
GCTGCCAGCCTCCCGCATCGGAGAGGCCACCACCGTAGGGCCAGGCTCACTAGTCATGCGTGGCGACGACGTCCCCGCCT
ACTCTCACTGGCAAGGAAACCCCATCGCCACCACAACGACCTAA

Upstream 100 bases:

>100_bases
AGCGCAGTCGGAGGCCCAAGTGTTGGCGGCTGCGGGTGATGTGGCGACAGCGCAGGCAATGTTGCGTCGGTTGGCTAACC
AGTTGGTTTTTGGGGTGTAG

Downstream 100 bases:

>100_bases
CGCTTACGACGCGCCACTAACCACAATGCTGCAGCCACCAACAGGCCCGCAGCACCGGCCAACAGCCACCGCAAGTAACC
ATTCGAACCAGTCAACGGCA

Product: putative peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1267; Mature: 1267

Protein sequence:

>1267_residues
MVVPEQFLRSDKAPRPRTLVDIFRSSVAAFPEAAALDCGDVLTYADLAELVDDRVAQLHAAGVGAGCRVGVRLPSGQPDL
YVTILAVLCAGAAYVPVDADDPDERAELVFGEAHVDAVWSVSGLRVTTAQAQPLTAGPRLEDTAWIIFTSGSTGKPKGVA
VSHRSAAAFVDAERELFVRDQPIGPDDRVLAGLSVAFDASCEEMWLAWGHGACLVPAPRSLVRTGLDLGPWLISRDISIV
STVPTLAGMWPAEALDNVRLLILGGEACSAELVARVASSRREVWNTYGPTEATVVTCAARLEAGQPVAIGLPLAGWDTAV
VGADGQPVAMGDVGELVIGGVGLARYLDPVKDREKFSAELGWERAYRSGDHVRLCEDGLYFVGRIDDQVKIGGRRIELGE
VEAHVAALPNVAQYAVVVRETAAGEKVLVAYVSPQVPDVDIDTSALDELPRAMVPRLVVLPEIPTTTSGKADKKALPWPL
ESAQVTGSDFTPTQQWLAQLWVDVLGVPVGDVDADFFVLGGTSLAAAGVVSRIRQKAPTMSVRDLYDHPRLGALAEVVEQ
LPGAAVTKRRELRPVPWVTRVAQATIIWLCATIRAASWVAWLLVLNNVAAGWGASWARPLPWLFVVLFTVLVATPVGRLP
LGAWSARLITARISPGDYPRGGVTHVRLWAAQRLFDAFGAGDIAGATWVNYCARALGAQVGRGVDLHTMPPVTGLLRLGD
HCAVEPEVDLSGVWVDGDVVHVGAIEIAEDARVGARSTLLPGTVIGAGAHIEAGSTVTGAVVKAGARWSGSPAAKVGRSK
HRFPNAHPPRRSRWVPVYGVSSLVLALLPLLAIAVGMVVVWRWQERTHTALWWWVPLGVVAAMGLYALLVLVLVRLLGWR
LAPGITAVRSARGWRVWCIERLLDDARTYLFPMYASLITPWWFRLLGAKVGKDVEISTAVMVPSLSEIRDRAFLADDTLI
GGYELGGGWMRLGRTIIGKRSFVGNSGIALQGRKLAKNSLVAVLSQVPKKARSGSNWWGSPPERMRRVTVNSCASDTSTF
YPTVGKKFLRAMVEILRLTAPMTSGFLLAAVLVSAQWLLGFGVVAALFGTGLALCVAGALAITITAAVKWCTVGRHRPGN
HPLWSWFVWLNELQDTFVEVVAAPWFFHHCTGSGLINSGLRLLGVRIGPGAWIDSYWFPETDLCNVGTAATVGPGTVVQT
HLFHDRVMSLDHVHIGAGATLAAHSVMLPASRIGEATTVGPGSLVMRGDDVPAYSHWQGNPIATTTT

Sequences:

>Translated_1267_residues
MVVPEQFLRSDKAPRPRTLVDIFRSSVAAFPEAAALDCGDVLTYADLAELVDDRVAQLHAAGVGAGCRVGVRLPSGQPDL
YVTILAVLCAGAAYVPVDADDPDERAELVFGEAHVDAVWSVSGLRVTTAQAQPLTAGPRLEDTAWIIFTSGSTGKPKGVA
VSHRSAAAFVDAERELFVRDQPIGPDDRVLAGLSVAFDASCEEMWLAWGHGACLVPAPRSLVRTGLDLGPWLISRDISIV
STVPTLAGMWPAEALDNVRLLILGGEACSAELVARVASSRREVWNTYGPTEATVVTCAARLEAGQPVAIGLPLAGWDTAV
VGADGQPVAMGDVGELVIGGVGLARYLDPVKDREKFSAELGWERAYRSGDHVRLCEDGLYFVGRIDDQVKIGGRRIELGE
VEAHVAALPNVAQYAVVVRETAAGEKVLVAYVSPQVPDVDIDTSALDELPRAMVPRLVVLPEIPTTTSGKADKKALPWPL
ESAQVTGSDFTPTQQWLAQLWVDVLGVPVGDVDADFFVLGGTSLAAAGVVSRIRQKAPTMSVRDLYDHPRLGALAEVVEQ
LPGAAVTKRRELRPVPWVTRVAQATIIWLCATIRAASWVAWLLVLNNVAAGWGASWARPLPWLFVVLFTVLVATPVGRLP
LGAWSARLITARISPGDYPRGGVTHVRLWAAQRLFDAFGAGDIAGATWVNYCARALGAQVGRGVDLHTMPPVTGLLRLGD
HCAVEPEVDLSGVWVDGDVVHVGAIEIAEDARVGARSTLLPGTVIGAGAHIEAGSTVTGAVVKAGARWSGSPAAKVGRSK
HRFPNAHPPRRSRWVPVYGVSSLVLALLPLLAIAVGMVVVWRWQERTHTALWWWVPLGVVAAMGLYALLVLVLVRLLGWR
LAPGITAVRSARGWRVWCIERLLDDARTYLFPMYASLITPWWFRLLGAKVGKDVEISTAVMVPSLSEIRDRAFLADDTLI
GGYELGGGWMRLGRTIIGKRSFVGNSGIALQGRKLAKNSLVAVLSQVPKKARSGSNWWGSPPERMRRVTVNSCASDTSTF
YPTVGKKFLRAMVEILRLTAPMTSGFLLAAVLVSAQWLLGFGVVAALFGTGLALCVAGALAITITAAVKWCTVGRHRPGN
HPLWSWFVWLNELQDTFVEVVAAPWFFHHCTGSGLINSGLRLLGVRIGPGAWIDSYWFPETDLCNVGTAATVGPGTVVQT
HLFHDRVMSLDHVHIGAGATLAAHSVMLPASRIGEATTVGPGSLVMRGDDVPAYSHWQGNPIATTTT
>Mature_1267_residues
MVVPEQFLRSDKAPRPRTLVDIFRSSVAAFPEAAALDCGDVLTYADLAELVDDRVAQLHAAGVGAGCRVGVRLPSGQPDL
YVTILAVLCAGAAYVPVDADDPDERAELVFGEAHVDAVWSVSGLRVTTAQAQPLTAGPRLEDTAWIIFTSGSTGKPKGVA
VSHRSAAAFVDAERELFVRDQPIGPDDRVLAGLSVAFDASCEEMWLAWGHGACLVPAPRSLVRTGLDLGPWLISRDISIV
STVPTLAGMWPAEALDNVRLLILGGEACSAELVARVASSRREVWNTYGPTEATVVTCAARLEAGQPVAIGLPLAGWDTAV
VGADGQPVAMGDVGELVIGGVGLARYLDPVKDREKFSAELGWERAYRSGDHVRLCEDGLYFVGRIDDQVKIGGRRIELGE
VEAHVAALPNVAQYAVVVRETAAGEKVLVAYVSPQVPDVDIDTSALDELPRAMVPRLVVLPEIPTTTSGKADKKALPWPL
ESAQVTGSDFTPTQQWLAQLWVDVLGVPVGDVDADFFVLGGTSLAAAGVVSRIRQKAPTMSVRDLYDHPRLGALAEVVEQ
LPGAAVTKRRELRPVPWVTRVAQATIIWLCATIRAASWVAWLLVLNNVAAGWGASWARPLPWLFVVLFTVLVATPVGRLP
LGAWSARLITARISPGDYPRGGVTHVRLWAAQRLFDAFGAGDIAGATWVNYCARALGAQVGRGVDLHTMPPVTGLLRLGD
HCAVEPEVDLSGVWVDGDVVHVGAIEIAEDARVGARSTLLPGTVIGAGAHIEAGSTVTGAVVKAGARWSGSPAAKVGRSK
HRFPNAHPPRRSRWVPVYGVSSLVLALLPLLAIAVGMVVVWRWQERTHTALWWWVPLGVVAAMGLYALLVLVLVRLLGWR
LAPGITAVRSARGWRVWCIERLLDDARTYLFPMYASLITPWWFRLLGAKVGKDVEISTAVMVPSLSEIRDRAFLADDTLI
GGYELGGGWMRLGRTIIGKRSFVGNSGIALQGRKLAKNSLVAVLSQVPKKARSGSNWWGSPPERMRRVTVNSCASDTSTF
YPTVGKKFLRAMVEILRLTAPMTSGFLLAAVLVSAQWLLGFGVVAALFGTGLALCVAGALAITITAAVKWCTVGRHRPGN
HPLWSWFVWLNELQDTFVEVVAAPWFFHHCTGSGLINSGLRLLGVRIGPGAWIDSYWFPETDLCNVGTAATVGPGTVVQT
HLFHDRVMSLDHVHIGAGATLAAHSVMLPASRIGEATTVGPGSLVMRGDDVPAYSHWQGNPIATTTT

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=474, Percent_Identity=26.7932489451477, Blast_Score=111, Evalue=6e-24,
Organism=Escherichia coli, GI1786801, Length=575, Percent_Identity=31.8260869565217, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17556356, Length=458, Percent_Identity=25.9825327510917, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564422, Length=497, Percent_Identity=27.1629778672032, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=497, Percent_Identity=27.1629778672032, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=536, Percent_Identity=23.6940298507463, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648676, Length=575, Percent_Identity=26.4347826086956, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24582852, Length=543, Percent_Identity=23.2044198895028, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581924, Length=364, Percent_Identity=28.2967032967033, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 135545; Mature: 135545

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVPEQFLRSDKAPRPRTLVDIFRSSVAAFPEAAALDCGDVLTYADLAELVDDRVAQLHA
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AGVGAGCRVGVRLPSGQPDLYVTILAVLCAGAAYVPVDADDPDERAELVFGEAHVDAVWS
CCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHEEECCHHHCCEEE
VSGLRVTTAQAQPLTAGPRLEDTAWIIFTSGSTGKPKGVAVSHRSAAAFVDAERELFVRD
CCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCCEEEEC
QPIGPDDRVLAGLSVAFDASCEEMWLAWGHGACLVPAPRSLVRTGLDLGPWLISRDISIV
CCCCCCCHHHCCCCEEECCCHHHHHHEECCCEEECCCCHHHHHCCCCCCCHHHHCCCHHH
STVPTLAGMWPAEALDNVRLLILGGEACSAELVARVASSRREVWNTYGPTEATVVTCAAR
HHHHHHHCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEAGQPVAIGLPLAGWDTAVVGADGQPVAMGDVGELVIGGVGLARYLDPVKDREKFSAEL
HCCCCCEEEEEEECCCCEEEECCCCCEEEECCHHHHHHCCHHHHHHHCCHHHHHHHHHHH
GWERAYRSGDHVRLCEDGLYFVGRIDDQVKIGGRRIELGEVEAHVAALPNVAQYAVVVRE
CHHHHHCCCCCEEEECCCCEEEEECCCEEEECCEEEEECHHHHHHHHCCCHHHHHHHHHH
TAAGEKVLVAYVSPQVPDVDIDTSALDELPRAMVPRLVVLPEIPTTTSGKADKKALPWPL
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
ESAQVTGSDFTPTQQWLAQLWVDVLGVPVGDVDADFFVLGGTSLAAAGVVSRIRQKAPTM
CCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
SVRDLYDHPRLGALAEVVEQLPGAAVTKRRELRPVPWVTRVAQATIIWLCATIRAASWVA
CHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLLVLNNVAAGWGASWARPLPWLFVVLFTVLVATPVGRLPLGAWSARLITARISPGDYPR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
GGVTHVRLWAAQRLFDAFGAGDIAGATWVNYCARALGAQVGRGVDLHTMPPVTGLLRLGD
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
HCAVEPEVDLSGVWVDGDVVHVGAIEIAEDARVGARSTLLPGTVIGAGAHIEAGSTVTGA
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCCHHHH
VVKAGARWSGSPAAKVGRSKHRFPNAHPPRRSRWVPVYGVSSLVLALLPLLAIAVGMVVV
HHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHEE
WRWQERTHTALWWWVPLGVVAAMGLYALLVLVLVRLLGWRLAPGITAVRSARGWRVWCIE
EEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHH
RLLDDARTYLFPMYASLITPWWFRLLGAKVGKDVEISTAVMVPSLSEIRDRAFLADDTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHEECCCCEE
GGYELGGGWMRLGRTIIGKRSFVGNSGIALQGRKLAKNSLVAVLSQVPKKARSGSNWWGS
CCEEECCHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPERMRRVTVNSCASDTSTFYPTVGKKFLRAMVEILRLTAPMTSGFLLAAVLVSAQWLLG
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FGVVAALFGTGLALCVAGALAITITAAVKWCTVGRHRPGNHPLWSWFVWLNELQDTFVEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAAPWFFHHCTGSGLINSGLRLLGVRIGPGAWIDSYWFPETDLCNVGTAATVGPGTVVQT
HHHHHHHHHCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
HLFHDRVMSLDHVHIGAGATLAAHSVMLPASRIGEATTVGPGSLVMRGDDVPAYSHWQGN
HHHHHHHHCCCEEEECCCCHHHHHHHCCCHHHCCCCEECCCCCEEEECCCCCCCCCCCCC
PIATTTT
EEEECCC
>Mature Secondary Structure
MVVPEQFLRSDKAPRPRTLVDIFRSSVAAFPEAAALDCGDVLTYADLAELVDDRVAQLHA
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AGVGAGCRVGVRLPSGQPDLYVTILAVLCAGAAYVPVDADDPDERAELVFGEAHVDAVWS
CCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHEEECCHHHCCEEE
VSGLRVTTAQAQPLTAGPRLEDTAWIIFTSGSTGKPKGVAVSHRSAAAFVDAERELFVRD
CCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCCEEEEC
QPIGPDDRVLAGLSVAFDASCEEMWLAWGHGACLVPAPRSLVRTGLDLGPWLISRDISIV
CCCCCCCHHHCCCCEEECCCHHHHHHEECCCEEECCCCHHHHHCCCCCCCHHHHCCCHHH
STVPTLAGMWPAEALDNVRLLILGGEACSAELVARVASSRREVWNTYGPTEATVVTCAAR
HHHHHHHCCCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEAGQPVAIGLPLAGWDTAVVGADGQPVAMGDVGELVIGGVGLARYLDPVKDREKFSAEL
HCCCCCEEEEEEECCCCEEEECCCCCEEEECCHHHHHHCCHHHHHHHCCHHHHHHHHHHH
GWERAYRSGDHVRLCEDGLYFVGRIDDQVKIGGRRIELGEVEAHVAALPNVAQYAVVVRE
CHHHHHCCCCCEEEECCCCEEEEECCCEEEECCEEEEECHHHHHHHHCCCHHHHHHHHHH
TAAGEKVLVAYVSPQVPDVDIDTSALDELPRAMVPRLVVLPEIPTTTSGKADKKALPWPL
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
ESAQVTGSDFTPTQQWLAQLWVDVLGVPVGDVDADFFVLGGTSLAAAGVVSRIRQKAPTM
CCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
SVRDLYDHPRLGALAEVVEQLPGAAVTKRRELRPVPWVTRVAQATIIWLCATIRAASWVA
CHHHHHCCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLLVLNNVAAGWGASWARPLPWLFVVLFTVLVATPVGRLPLGAWSARLITARISPGDYPR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
GGVTHVRLWAAQRLFDAFGAGDIAGATWVNYCARALGAQVGRGVDLHTMPPVTGLLRLGD
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
HCAVEPEVDLSGVWVDGDVVHVGAIEIAEDARVGARSTLLPGTVIGAGAHIEAGSTVTGA
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCCHHHH
VVKAGARWSGSPAAKVGRSKHRFPNAHPPRRSRWVPVYGVSSLVLALLPLLAIAVGMVVV
HHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHEE
WRWQERTHTALWWWVPLGVVAAMGLYALLVLVLVRLLGWRLAPGITAVRSARGWRVWCIE
EEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHH
RLLDDARTYLFPMYASLITPWWFRLLGAKVGKDVEISTAVMVPSLSEIRDRAFLADDTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHEECCCCEE
GGYELGGGWMRLGRTIIGKRSFVGNSGIALQGRKLAKNSLVAVLSQVPKKARSGSNWWGS
CCEEECCHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPERMRRVTVNSCASDTSTFYPTVGKKFLRAMVEILRLTAPMTSGFLLAAVLVSAQWLLG
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FGVVAALFGTGLALCVAGALAITITAAVKWCTVGRHRPGNHPLWSWFVWLNELQDTFVEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAAPWFFHHCTGSGLINSGLRLLGVRIGPGAWIDSYWFPETDLCNVGTAATVGPGTVVQT
HHHHHHHHHCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
HLFHDRVMSLDHVHIGAGATLAAHSVMLPASRIGEATTVGPGSLVMRGDDVPAYSHWQGN
HHHHHHHHCCCEEEECCCCHHHHHHHCCCHHHCCCCEECCCCCEEEECCCCCCCCCCCCC
PIATTTT
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA