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The map label for this gene is panC [H]

Identifier: 38234557

GI number: 38234557

Start: 2043495

End: 2044274

Strand: Reverse

Name: panC [H]

Synonym: DIP1993

Alternate gene names: 38234557

Gene position: 2044274-2043495 (Counterclockwise)

Preceding gene: 38234558

Following gene: 38234554

Centisome position: 82.14

GC content: 55.9

Gene sequence:

>780_bases
GTGTTTGAATACCGTGCTGCCACACTTTTCGACGCAGCAAAAATCGCCATGGTGGCACGCGCCTTTAAAAAACAAGGAAA
GCCCGTCGTATTCGTCCCACTCGGCAGTGGAGTACATGCCGGACACCGCGCATTGCTGCGCGCCGCACGACGAATCCCCG
GTGGCATTGTGATCGTGGCCAGCCAGCACGATGATCCTGCCTTTGCAGAAGAAGGCGTTGATGCAGTGTTCTTGTACGAG
CCGGAAGAACTGCGCACCCTTATTCAGGTGCCGAGCATCGGGATGCAGCCAGCTCAAGAACTCTCAGAGGCAGTCACCCG
TCGAATCACCCTAATGAACCTCGTTGGTCCCAGCGATGTGATCTTTGGTGAAAAAGACTACGAGCTACTGGTGCGCACCC
AGCAAGCTCTCAACGACCTCAACATTCACGTCACCGTGCACTCCGTACCTACTGTGCGCATGCCGGACGGAATCGCCATT
TCTTTGCGCAACGCCACCGTTCCTGAACAAGATCGCGAACACGCACTCGCACTATCGGCAGCCATCACCGCCGGAGCGCA
TGCGGCAGAAGATGGCAAAGAAGCCGTGCTGCGAGTTGCCCATCAAGTGCTGGAATCGGCTGGTGTGACTCCTGACTATG
TGGAACTTCGTGCCATGAATCTTGGTGAAGCGCCAAAAACCGGCGACGCTAGGTTATTTGTAGCCGCAACCTTTGGGGAT
GTGCAGCTAACAGATAACGCCGGTGTGCCGGTGGGAGTGGGATTTAAAAACCTCGACTAG

Upstream 100 bases:

>100_bases
CGCCCAGCTTGCCCGTCGAAGCGGGGAAGTGTTCCGCAACAACGACGTGGAGTTGTGGGCAATGAATCAAGAACAAAACA
ACACATAAGGAATACAACGA

Downstream 100 bases:

>100_bases
GAGGACACTAGGAGGACTAGGAGGCGGTGATACGGGCTTCGGCGTCCTCGCGGGAGGCGTCGAAAAGCGTGCGATCCAAG
ATCTTTTCCTGGCGGGCCAC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MFEYRAATLFDAAKIAMVARAFKKQGKPVVFVPLGSGVHAGHRALLRAARRIPGGIVIVASQHDDPAFAEEGVDAVFLYE
PEELRTLIQVPSIGMQPAQELSEAVTRRITLMNLVGPSDVIFGEKDYELLVRTQQALNDLNIHVTVHSVPTVRMPDGIAI
SLRNATVPEQDREHALALSAAITAGAHAAEDGKEAVLRVAHQVLESAGVTPDYVELRAMNLGEAPKTGDARLFVAATFGD
VQLTDNAGVPVGVGFKNLD

Sequences:

>Translated_259_residues
MFEYRAATLFDAAKIAMVARAFKKQGKPVVFVPLGSGVHAGHRALLRAARRIPGGIVIVASQHDDPAFAEEGVDAVFLYE
PEELRTLIQVPSIGMQPAQELSEAVTRRITLMNLVGPSDVIFGEKDYELLVRTQQALNDLNIHVTVHSVPTVRMPDGIAI
SLRNATVPEQDREHALALSAAITAGAHAAEDGKEAVLRVAHQVLESAGVTPDYVELRAMNLGEAPKTGDARLFVAATFGD
VQLTDNAGVPVGVGFKNLD
>Mature_259_residues
MFEYRAATLFDAAKIAMVARAFKKQGKPVVFVPLGSGVHAGHRALLRAARRIPGGIVIVASQHDDPAFAEEGVDAVFLYE
PEELRTLIQVPSIGMQPAQELSEAVTRRITLMNLVGPSDVIFGEKDYELLVRTQQALNDLNIHVTVHSVPTVRMPDGIAI
SLRNATVPEQDREHALALSAAITAGAHAAEDGKEAVLRVAHQVLESAGVTPDYVELRAMNLGEAPKTGDARLFVAATFGD
VQLTDNAGVPVGVGFKNLD

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=270, Percent_Identity=27.037037037037, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 27730; Mature: 27730

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYRAATLFDAAKIAMVARAFKKQGKPVVFVPLGSGVHAGHRALLRAARRIPGGIVIVA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEE
SQHDDPAFAEEGVDAVFLYEPEELRTLIQVPSIGMQPAQELSEAVTRRITLMNLVGPSDV
ECCCCCCHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCE
IFGEKDYELLVRTQQALNDLNIHVTVHSVPTVRMPDGIAISLRNATVPEQDREHALALSA
EECCCCHHHHHHHHHHHCCCEEEEEEECCCEEECCCCEEEEEECCCCCCCHHHHHHHHHH
AITAGAHAAEDGKEAVLRVAHQVLESAGVTPDYVELRAMNLGEAPKTGDARLFVAATFGD
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECC
VQLTDNAGVPVGVGFKNLD
EEEECCCCCEEECCCCCCC
>Mature Secondary Structure
MFEYRAATLFDAAKIAMVARAFKKQGKPVVFVPLGSGVHAGHRALLRAARRIPGGIVIVA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEE
SQHDDPAFAEEGVDAVFLYEPEELRTLIQVPSIGMQPAQELSEAVTRRITLMNLVGPSDV
ECCCCCCHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCE
IFGEKDYELLVRTQQALNDLNIHVTVHSVPTVRMPDGIAISLRNATVPEQDREHALALSA
EECCCCHHHHHHHHHHHCCCEEEEEEECCCEEECCCCEEEEEECCCCCCCHHHHHHHHHH
AITAGAHAAEDGKEAVLRVAHQVLESAGVTPDYVELRAMNLGEAPKTGDARLFVAATFGD
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECC
VQLTDNAGVPVGVGFKNLD
EEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA