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The map label for this gene is clpC [H]

Identifier: 38234547

GI number: 38234547

Start: 2030233

End: 2032884

Strand: Reverse

Name: clpC [H]

Synonym: DIP1983

Alternate gene names: 38234547

Gene position: 2032884-2030233 (Counterclockwise)

Preceding gene: 38234548

Following gene: 38234546

Centisome position: 81.69

GC content: 57.77

Gene sequence:

>2652_bases
TTGAAGGGTGTGAACATGTTCGAGCGGTTTACCGATCGTGCACGTCGCGTTATCGTTCTGGCACAGGAAGAAGCGCGCGG
CCTCAATCACAATTACATCGGCACCGAGCACATCCTGCTCGGACTTATTCACGAGGGTGAGGGCGTGGCCGCTAAGGCGC
TCGAGTCCATGGGCATCTCCCTTGAAGCAGTACGCCAAGAGGTAGAAGAAATCATCGGCCACGGCTCCGAGCCACCAGCT
GGCCACATTCCTTTTACTCCACGTGCCAAGAAGGTACTTGAGCTCTCCTTGCGTGAGGGTCTGCAGATGGGACATAAGTA
CATCGGTACTGAGTTCCTGCTGCTCGGCCTTATCCGTGAGGGCGACGGCGTAGCCGCACAAGTTTTGGTCAAGCTCGGCG
CTGACCTGCCCCGTGTACGCCAGCAGGTTATCCAGCTTCTTTCCGGCTATGAGGGGGGCGAAAGCCCAGAAAACAATAAC
GAGGGCGAGGCTGTGGGTGCTGGTACTGGCGCTGGCCGTGCTGGCCGCGGTGGTGGCGCAGGCGAGCGCTCCAACTCCTT
GGTTTTGGACCAGTTTGGTCGCAACCTCACCCAGGCTGCTAAGGAAGGCAAGCTGGATCCTGTGGTGGGTCGTGAGCAGG
AAATTGAGCGCATCATGCAGGTGCTCTCACGTCGTACCAAGAACAACCCAGTTCTTATCGGTGAGCCAGGTGTTGGTAAG
ACCGCTGTTGTAGAAGGCCTAGCTCTAGACATCGTTAACGGCAAGGTGCCAGAAACGCTGAAAGACAAGCAGGTTTACTC
TCTTGACCTCGGCTCCTTGGTGGCAGGTTCGCGCTACCGTGGTGACTTCGAAGAGCGCCTGAAGAAGGTTCTCAAGGAGA
TCAACCAGCGTGGCGACATCATCTTGTTCATCGATGAGATCCACACCCTCGTCGGTGCCGGTGCCGCAGAAGGCGCTATC
GACGCTGCCAGCTTGCTCAAACCTAAACTGGCTCGTGGTGAGCTACAGACCATCGGTGCTACCACTTTGGACGAGTACCG
CAAGCACATCGAAAAGGACGCCGCACTTGAGCGTCGTTTCCAGCCAGTGCAGGTTCCAGAGCCTTCCGTCGATATGACCA
TCGAGATCCTCAAGGGGCTACGCGACCGCTACGAGGCACACCACCGCGTCTCCATCACCGATGGGGCTCTCGCAGCAGCA
GCACAGCTGTCCGATCGCTACATCAACGATCGCTTCTTGCCAGATAAGGCTGTTGACCTTATCGACGAAGCCGGCGCACG
CATGCGTATCAAGCGCATGACCGCACCGGAATCCATCCGCAAGGTAGACGATCAGATCGCGGAAGTCCGTCGTGAGAAGG
AAGCCGCAATCGATGCCCAAGACTTTGAAAAGGCCGCTGGCCTGCGCGACACCGAGCGCAAGTTAGGTGAAGAGCGCGCT
GAGAAAGAAAAGCAGTGGCGCTCCGGCGACCTAGAAGACATCGCCGAGGTCGGCGAGGAGCAAATCGCTGAGGTGCTGGG
CAACTGGACTGGTATCCCAGTGTTCAAGCTGACCGAGGAAGAATCCTCCCGTCTGCTGCACATGGAAGAGGAGCTACACA
AGCGCATCATCGGCCAAGACGATGCCGTCAAGAGTGTTTCTCGCGCCATCCGCCGCACCCGCGCTGGCCTCAAGGACCCA
CGCCGTCCTTCCGGCTCCTTCATCTTCGCCGGCCCATCTGGCGTGGGTAAGACCGAGCTATCCAAGTCACTGGCCAACTT
CCTGTTCGGCGACGACGACGCCCTAATCCAGATCGACATGGGCGAGTTCCACGACCGCTTCACCGCGTCCCGTCTGTTCG
GTGCCCCTCCAGGATATGTGGGCTACGACGAGGGCGGTCAGCTCACCGAGAAGGTCCGCCGCAAGCCATTCTCCGTGGTG
CTTTTCGACGAAATCGAAAAGGCGCACAAGGAGATCTACAACACCTTGCTGCAGGTCCTCGAAGAAGGTCGCCTCACCGA
CGGCCAAGGCCGCGTGGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCCAACCTGGGTACCCAAGACATCTCTAAGG
CTGTGGGCATGGGCTTTAGCTCTGTCGGCGAGCACGATGCCGATGGCCAGTACGACCGCATGAAGCAGAAGGTCAACGAC
GAGCTAAAGAAGCACTTCCGCCCTGAGTTCCTCAACCGTATCGACGAAATCGTGGTATTCCACCAGCTCACCCAAGAGCA
GATCGTCGAAATGGTGGACCTGCTCATCGGACGCGTATCCAAGGCACTTGCTCAAAAAGACATGGGCATCGAGCTCACCG
AAAAGGCCAAGAACCTGCTGGCAAAGCGTGGATTCGATCCAGTACTGGGTGCACGACCATTGCGTCGCACCATCCAGCGC
GAGATCGAAGACGTACTCTCCGAGAAGATCCTCTTCGGTGAGGTCGGCGCTGGTGAGATCGTCACCGTGGATGTTGAAGG
CTGGGACGGCGAATCCAAGGAAACCGACAAGGCTTCCTTCACCTTCACCCCACGCGTGAAGCCGCTGCCAGACGAGTTCG
AAGAGGCAACCCCATCTGAGGAAGCTCAAGAAGCAGTGATTAACGCTGCTGAGACTGAGGTTCCAGAAGAAGAAGTCAAC
ATCGAAAACTAA

Upstream 100 bases:

>100_bases
TGCTTGATGTTCGAATTTTTACAGGGGTGGGCCAGAAAATGGGAAATCAATGTCACGCATGGGCGTTACAGTGGGTGCAA
CTACTTAACAAAAGCCAACT

Downstream 100 bases:

>100_bases
TAGCGGCACTATTTCACCCGAGGGAGCACCATGGGAATCCAATATCGCAAGCGCAAAAAGCTGGGCAAAAACAGTTGGCT
CAACCTGTCCGGCTCCGGTG

Product: ATP-dependent Clp protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 883; Mature: 883

Protein sequence:

>883_residues
MKGVNMFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPA
GHIPFTPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNN
EGEAVGAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGK
TAVVEGLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAI
DAASLLKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAA
AQLSDRYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERA
EKEKQWRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQDDAVKSVSRAIRRTRAGLKDP
RRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVV
LFDEIEKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVND
ELKKHFRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQR
EIEDVLSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEVN
IEN

Sequences:

>Translated_883_residues
MKGVNMFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPA
GHIPFTPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNN
EGEAVGAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGK
TAVVEGLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAI
DAASLLKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAA
AQLSDRYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERA
EKEKQWRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQDDAVKSVSRAIRRTRAGLKDP
RRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVV
LFDEIEKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVND
ELKKHFRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQR
EIEDVLSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEVN
IEN
>Mature_883_residues
MKGVNMFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPA
GHIPFTPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNN
EGEAVGAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGK
TAVVEGLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAI
DAASLLKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAA
AQLSDRYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERA
EKEKQWRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQDDAVKSVSRAIRRTRAGLKDP
RRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVV
LFDEIEKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVND
ELKKHFRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQR
EIEDVLSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEVN
IEN

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=35.5704697986577, Blast_Score=189, Evalue=1e-47,
Organism=Escherichia coli, GI1788943, Length=883, Percent_Identity=44.960362400906, Blast_Score=715, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=838, Percent_Identity=38.1861575178998, Blast_Score=513, Evalue=1e-146,
Organism=Saccharomyces cerevisiae, GI6320464, Length=702, Percent_Identity=47.2934472934473, Blast_Score=616, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6323002, Length=944, Percent_Identity=36.864406779661, Blast_Score=548, Evalue=1e-156,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 97573; Mature: 97573

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGVNMFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGIS
CCCHHHHHHHHHHCCEEEEEECHHHCCCCCCCCCHHHHHEEEHCCCCCHHHHHHHHHCCC
LEAVRQEVEEIIGHGSEPPAGHIPFTPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNNEGEAVGAGTGAGRAGRGGGA
CCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
GERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGK
CCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCH
TAVVEGLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDI
HHHHHHHHHEECCCCCCCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
ILFIDEIHTLVGAGAAEGAIDAASLLKPKLARGELQTIGATTLDEYRKHIEKDAALERRF
EEEHHHHHHHHCCCCCCCHHHHHHHHCCHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCC
QPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAAAQLSDRYINDRFLPDKAVDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHH
IDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERA
HHHCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHH
EKEKQWRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQD
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
DAVKSVSRAIRRTRAGLKDPRRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDM
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEC
GEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEKAHKEIYNTLLQVL
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
EEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVND
HHCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHH
ELKKHFRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AKRGFDPVLGARPLRRTIQREIEDVLSEKILFGEVGAGEIVTVDVEGWDGESKETDKASF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCEE
TFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEVNIEN
EECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MKGVNMFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGIS
CCCHHHHHHHHHHCCEEEEEECHHHCCCCCCCCCHHHHHEEEHCCCCCHHHHHHHHHCCC
LEAVRQEVEEIIGHGSEPPAGHIPFTPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIRE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNNEGEAVGAGTGAGRAGRGGGA
CCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
GERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGK
CCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCH
TAVVEGLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDI
HHHHHHHHHEECCCCCCCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
ILFIDEIHTLVGAGAAEGAIDAASLLKPKLARGELQTIGATTLDEYRKHIEKDAALERRF
EEEHHHHHHHHCCCCCCCHHHHHHHHCCHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCC
QPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAAAQLSDRYINDRFLPDKAVDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHH
IDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERA
HHHCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHH
EKEKQWRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQD
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
DAVKSVSRAIRRTRAGLKDPRRPSGSFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDM
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEC
GEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEKAHKEIYNTLLQVL
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
EEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVND
HHCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHH
ELKKHFRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AKRGFDPVLGARPLRRTIQREIEDVLSEKILFGEVGAGEIVTVDVEGWDGESKETDKASF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCEE
TFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEVNIEN
EECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]