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The map label for this gene is insK [C]

Identifier: 38234527

GI number: 38234527

Start: 2010331

End: 2011782

Strand: Direct

Name: insK [C]

Synonym: DIP1963

Alternate gene names: 38234527

Gene position: 2010331-2011782 (Clockwise)

Preceding gene: 38234525

Following gene: 38234528

Centisome position: 80.78

GC content: 48.97

Gene sequence:

>1452_bases
TTGATTCGCCAAGCCCAAAATTCTGTCCGCTGCTTTACGGGGGATGCGGACGGAATCTTGGAGGATTCCATTATGAACCG
TTCCTACACCAACACGCAGAAGCGCACAGCACTGCGGGTCTACAAACGCACACAATCAGTGACTAAAACAGTCCGCGAAC
TCGGCTACCCAGGCAGATGGACCCTGTATAAATGGCTACGCGAGCCCAAAACCCCACCACAACCACGTAAACAAGCCAAA
ACCCTGACCCACTACCCATACGAAGTCAAACTTCGCGCAGTAGAACTTTTCCACAATGGTTGGCGACCAGCTGATATTGC
CCAGGAATGCTGCCTACACACTCACGCCAGCGTCTATGCTTGGGCGCAACGCTACCGTAAGGAAGGACAATGGGGCTTGA
TGTCGAAAAAAGAACGCGCAGGCCATGGCCGCATCCCTACTAAAGCAGCACTAGAAAAATCATTGCCGGATAATCCAACA
CAGTTAAAACAGCAGATGGCCACGCTGCTGGTAGAAAAAGCCGTGTTGGAAAAGGAGCTGGAAATTATAAAAAAAGACGT
AAGCGTCATCCCCGGTCAGCTGAGTAATAAGCACAAAACCGACGTGGTTGACGCTTTGCGTAGCACGTTTCCATTAGCAA
TGCTGCTCGCTGCTAGTGGTCTTGCTGCATCCAGTTTCTATTACCACCTGAAAAAACGACGCATGCCTGATAAGCACGCA
GCTATTCGCAGCATGGTGCACCGCATCAGTTCTGATTCACATAATACCTATGGTTATCGCCGTATCTGGTGGCAGTTACG
ACATTTAGGCATAACTATCAGTGAAAAAGTAGTTCGCAGGCTCATGCGCGAAGAAGCAATTACGGTGCGGTTTCCGAAGC
GGAAGGTGAAATATTCCAGTTATCAAGGAGAAATTTCTCCGGCTCCGCCGAACCTGGTCAACCGTTGTTTTCATGCCACT
GCTGCGAATACGTTGTGGCTGACTGATATTAGTGTTTTCGCTGTGAATGAGGGGCGGGTGTATTTGTCTGTGATTATTGA
TTGTTTCGATGGCAAAGTCGTTGCTGCTAAGACGAGTGTGAATCCCACTATGGAGTTAGCAGAATCTACGCTGCAGGCCG
CTATTGATGCTGAGGGTCTTCCACCGGATGGTTCATTAGTGATTCATTCAGATCGTGGTGTGCATTACCGTGGTCGGAGT
TGGCATAGTCTGACTGCGAAATATGGCATCGTTCGTTCGATGTCGAAAAAGGGGTGTAGTCCTGACAATGCGGCATGCGA
GGGGTTTTTCGGGCGGATGAAAAATGAGATGTATTACGGCAAGAGGTGGCAGACAATCCAAGAGCTTGACGATGCCATTG
CTGCTTATATCGAGTTTTATAACAATCATCGCATTAAAGTTAGTCTCAATGGTATGAGTATCGCGCGTTATCGCATGGCT
GCGGTAGCGTGA

Upstream 100 bases:

>100_bases
CCACTGAACTGCCGGAATAATCGATATAGGTAAAGTTAATTACGCCTTGGTTGCGAACCAAAGGGTCAACAACTTTCTTA
ACCGAATCAACAAACTGGGG

Downstream 100 bases:

>100_bases
GGTTGAAAGTGTCTAACAAAACGTCCGCATCCCCAAATGTCCCTTAAGCCGGATTCCGTGGGTAGTGCGTTGGGTGAGAT
TTTGTCGGATGTCGTGGAAA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MIRQAQNSVRCFTGDADGILEDSIMNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAK
TLTHYPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYRKEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPT
QLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHA
AIRSMVHRISSDSHNTYGYRRIWWQLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHAT
AANTLWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRS
WHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMA
AVA

Sequences:

>Translated_483_residues
MIRQAQNSVRCFTGDADGILEDSIMNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAK
TLTHYPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYRKEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPT
QLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHA
AIRSMVHRISSDSHNTYGYRRIWWQLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHAT
AANTLWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRS
WHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMA
AVA
>Mature_483_residues
MIRQAQNSVRCFTGDADGILEDSIMNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAK
TLTHYPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYRKEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPT
QLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHA
AIRSMVHRISSDSHNTYGYRRIWWQLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSSYQGEISPAPPNLVNRCFHAT
AANTLWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRS
WHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMA
AVA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=262, Percent_Identity=27.4809160305344, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789981, Length=277, Percent_Identity=38.9891696750903, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788405, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787263, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786753, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786570, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786490, Length=277, Percent_Identity=27.0758122743682, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 55065; Mature: 55065

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQAQNSVRCFTGDADGILEDSIMNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRW
CCCCCCCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYA
HHHHHHHCCCCCCCHHHHHHHHHCCCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHH
WAQRYRKEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKEL
HHHHHHHCCCCCCCCCHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EIIKKDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
AIRSMVHRISSDSHNTYGYRRIWWQLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCHHCCCCC
YQGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSV
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCC
NPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCS
CHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCC
PDNAACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHH
AVA
HCC
>Mature Secondary Structure
MIRQAQNSVRCFTGDADGILEDSIMNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRW
CCCCCCCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYA
HHHHHHHCCCCCCCHHHHHHHHHCCCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHH
WAQRYRKEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKEL
HHHHHHHCCCCCCCCCHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EIIKKDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
AIRSMVHRISSDSHNTYGYRRIWWQLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCHHCCCCC
YQGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSV
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCC
NPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCS
CHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCC
PDNAACEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHH
AVA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]